Neural induction: old problem, new findings, yet more questions

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The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

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Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

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Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

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Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

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HNF-3β is essential for node and notochord formation in mouse development

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Vertebrate neurogenesis is counteracted by Sox1–3 activity

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Induction of epidermis and inhibition of neural fate by Bmp-4

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Neural Induction by the Secreted Polypeptide Noggin

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The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

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Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation

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Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

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Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

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Axis Development and Early Asymmetry in Mammals

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Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

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DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN <i>XENOPUS</i> EMBRYOS

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The Xenopus Dorsalizing Factor Gremlin Identifies a Novel Family of Secreted Proteins that Antagonize BMP Activities

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Twenty Pairs of Sox

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Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

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Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages

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Initiation of neural induction by FGF signalling before gastrulation

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SIP1, a Novel Zinc Finger/Homeodomain Repressor, Interacts with Smad Proteins and Binds to 5′-CACCT Sequences in Candidate Target Genes

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Inhibition of activin receptor signaling promotes neuralization in Xenopus

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Cerberus-like is a secreted factor with neuralizing activity expressed in the anterior primitive endoderm of the mouse gastrula

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Early Steps in the Development of the Forebrain

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Ventral and Lateral Regions of the Zebrafish Gastrula, Including the Neural Crest Progenitors, Are Established by abmp2b/swirlPathway of Genes

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Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural inductionPreprint

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Gastrulation: from cells to embryo

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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.

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On the function of BMP‐4 in patterning the marginal zone of the Xenopus embryo.

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Functional Analysis of Chicken Sox2 Enhancers Highlights an Array of Diverse Regulatory Elements that Are Conserved in Mammals

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Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development

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Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

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The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4

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nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

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Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

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Embryonic induction - molecular prospects

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The zebrafish organizer requires chordino

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Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.Preprint

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Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

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Vertebrate Embryonic Cells Will Become Nerve Cells Unless Told Otherwise

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Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

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Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1

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Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo

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Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus

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Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural developmentPreprint

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The transcription factor HNF3β is required in visceral endoderm for normal primitive streak morphogenesis

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