The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Exosomes in developmental signalling
Open accessAbstract
In order to achieve coordinated growth and patterning during development, cells must communicate with one another, sending and receiving signals that regulate their activities. Such developmental signals can be soluble, bound to the extracellular matrix, or tethered to the surface of adjacent cells. Cells can also signal by releasing exosomes – extracellular vesicles containing bioactive molecules such as RNA, DNA and enzymes. Recent work has suggested that exosomes can also carry signalling proteins, including ligands of the Notch receptor and secreted proteins of the Hedgehog and WNT families. Here, we describe the various types of exosomes and their biogenesis. We then survey the experimental strategies used so far to interfere with exosome formation and critically assess the role of exosomes in developmental signalling.
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Citations
Cites
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Background
Cited by
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
Nusse, R., & Clevers, H. (2017) · Cell · doi:10.1016/j.cell.2017.05.016 · Cited by 4,342
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Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
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Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Mashouri, L., Yousefi, H., Aref, A. R., Ahadi, A. M., Molaei, F., & Alahari, S. K. (2019) · Molecular Cancer · doi:10.1186/s12943-019-0991-5 · Cited by 1,363
ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes
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Metadata
- Authors
- McGough, I. J., & Vincent, J.-P.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2016-07-15
- Volume
- 143
- Issue
- 14
- Pages
- 2482-2493
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2502341044
- Cited by
- 208
- References
- 21
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- hybrid
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