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Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice

Watari, K., Shibata, T., Nabeshima, H., Shinoda, A., Fukunaga, Y., Kawahara, A., Karasuyama, K., Fukushi, J.-I., Iwamoto, Y., Kuwano, M., et al. (2016) · Scientific Reports · doi:10.1038/srep19470 · Cited by 36

The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion

Sharma, A. R., Mendonca, J., Ying, J., Kim, H.-S., Verdone, J. E., Zarif, J. C., Carducci, M. A., Hammers, H. J., Pienta, K. J., & Kachhap, S. K. (2017) · Molecular Oncology · doi:10.1002/1878-0261.12059 · Cited by 39

Lipid metabolism alterations in peripheral neuropathies

Silva, A., Prior, R. C., D’Antonio, M., Swinnen, J. V., & Bosch, L. V. D. (2025) · Neuron · doi:10.1016/j.neuron.2025.04.006 · Cited by 33

Functional characterization of mutant genes associated with autosomal dominant familial hypercholesterolemia: Integration and evolution of genetic diagnosis

Taranto, M. D. D., D'Agostino, M. N., & Fortunato, G. (2015) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2015.06.007 · Cited by 33

Crystal and solution structure of NDRG1, a membrane‐binding protein linked to myelination and tumour suppression

Mustonen, V., Muruganandam, G., Loris, R., Kursula, P., & Ruskamo, S. (2020) · FEBS Journal · doi:10.1111/febs.15660 · Cited by 31

Phosphoproteomic identification of vasopressin V2 receptor-dependent signaling in the renal collecting duct

Deshpande, V., Kao, A. R., Raghuram, V., Datta, A., Chou, C., & Knepper, M. A. (2019) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00281.2019 · Cited by 30

Nerve Biopsy Is Still Useful in Some Inherited Neuropathies

Duchesne, M., Mathis, S., Richard, L., Magdelaine, C., Corcia, P., Nouioua, S., Tazir, M., Magy, L., & Vallat, J. (2017) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlx111 · Cited by 29

An altered lipid metabolism characterizes Charcot-Marie-Tooth type 2B peripheral neuropathy

Giudetti, A. M., Guerra, F., Longo, S., Beli, R., Romanò, R., Manganelli, F., Nolano, M., Mangini, V., Santoro, L., & Bucci, C. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158805 · Cited by 29

N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly

Schweitzer, C. J., Zhang, F., Boyer, A., Valdez, K., Cam, M., & Liang, T. J. (2017) · Journal of Virology · doi:10.1128/jvi.01166-17 · Cited by 28

Dysregulation of ErbB Receptor Trafficking and Signaling in Demyelinating Charcot-Marie-Tooth Disease

Lee, S. M., Chin, L., & Li, L. (2016) · Molecular Neurobiology · doi:10.1007/s12035-015-9668-2 · Cited by 27

A Unique TGFB1-Driven Genomic Program Links Astrocytosis, Low-Grade Inflammation and Partial Demyelination in Spinal Cord Periplaques from Progressive Multiple Sclerosis Patients

Nataf, S., Barritault, M., & Pays, L. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18102097 · Cited by 26

Identification and functional characterization of two missense mutations in NDRG1 associated with Charcot‐Marie‐Tooth disease type 4D

Li, L., Liu, G., Liu, Z., Lu, C., & Wu, Z. (2017) · Human Mutation · doi:10.1002/humu.23309 · Cited by 26

N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia

Park, J. S., Gabel, A. M., Kassir, P., Kang, L., Chowdhary, P. K., Osei-Ntansah, A., Tran, N. D., Viswanathan, S., Canales, B. I.-I., Ding, P., et al. (2022) · eLife · doi:10.7554/elife.74031 · Cited by 23

BRCA1/BRCA2‐containing complex subunit 3 controls oligodendrocyte differentiation by dynamically regulating lysine 63‐linked ubiquitination

Wang, C., Deneen, B., & Tzeng, S. (2019) · Glia · doi:10.1002/glia.23660 · Cited by 23

NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization

Sahni, S., Gillson, J., Park, K. C., Chiang, S., Leck, L. Y. W., Jansson, P. J., & Richardson, D. R. (2020) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2020.129625 · Cited by 23

The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes

Khan, T. G., Ginsburg, D., & Emmer, B. T. (2022) · Journal of Lipid Research · doi:10.1016/j.jlr.2022.100248 · Cited by 21

The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Feldt, M., Menard, J. A., Rosendahl, A. H., Lettiero, B., Bendahl, P., Belting, M., & Borgquist, S. (2020) · Cancer & Metabolism · doi:10.1186/s40170-020-00231-8 · Cited by 21

Differential expression and hypoxia‐mediated regulation of the N‐myc downstream regulated gene family

Le, N., Hufford, T. M., Park, J. S., & Brewster, R. M. (2021) · The FASEB Journal · doi:10.1096/fj.202100443r · Cited by 21

Characterization of the prognostic values of the NDRG family in gastric cancer

Yu, C., Hao, X., Zhang, S., Hu, W., Li, J., Sun, J. P., & Zheng, M. (2019) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756284819858507 · Cited by 20

Held Up in Traffic—Defects in the Trafficking Machinery in Charcot-Marie-Tooth Disease

Markworth, R., Bähr, M., & Burk, K. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.695294 · Cited by 19

The Role of Vesicle Trafficking and Release in Oligodendrocyte Biology

Reiter, C. R., & Bongarzone, E. R. (2019) · Neurochemical Research · doi:10.1007/s11064-019-02913-2 · Cited by 17

N‐myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination

Marechal, D., Dansu, D. K., Castro, K., Patzig, J., Magri, L., Inbar, B., Gacias, M., Moyon, S., & Casaccia, P. (2022) · Glia · doi:10.1002/glia.24108 · Cited by 17

Comparative Transcriptomics Unravels Prodigiosin's Potential Cancer-Specific Activity Between Human Small Airway Epithelial Cells and Lung Adenocarcinoma Cells

Davient, B., Ng, J. P. Z., Xiao, Q., Li, L., & Yang, L. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00573 · Cited by 17

Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism

Zhang, C., Xiang, D., Zhao, Q., Jiang, S., Wang, C., Hui-xian, Y., Huang, Y., Yuan, Y., Liu, X., Huang, Z., et al. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175195 · Cited by 14

NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazones

Azad, M. G., Russell, T. M., Gu, X., Zhao, X., Richardson, V., Wijesinghe, T. P., Babu, G., Guo, X., Kaya, B., Dharmasivam, M., et al. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.110230 · Cited by 13

Neurodegenerative Disorder Risk in Krabbe Disease Carriers

Vantaggiato, L., Shaba, E., Carleo, A., Bezzini, D., Pannuzzo, G., Luddi, A., Piomboni, P., Bini, L., & Bianchi, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113537 · Cited by 13

Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D

Skedsmo, F. S., Espenes, A., Tranulis, M. A., Matiasek, K., Gunnes, G., Bjerkås, I., Moe, L., Røed, S. S., Berendt, M., Fredholm, M., et al. (2021) · Neuromuscular Disorders · doi:10.1016/j.nmd.2020.11.010 · Cited by 11

Insight into the Regulation of NDRG1 Expression

Saponaro, C., Gammaldi, N., Cavallo, V., Ramírez‐Morales, M. A., Zito, F. A., Sonnessa, M., Vari, F., Serra, I., Summa, S. D., Giudetti, A. M., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083582 · Cited by 11

Deciphering the Genetic Crosstalk between Microglia and Oligodendrocyte Precursor Cells during Demyelination and Remyelination Using Transcriptomic Data

Enrich-Bengoa, J., Manich, G., Degano, I. R., & Perálvarez‐Marín, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314868 · Cited by 11

SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes

Moriwaki, Y., Yuho, O., Ishii, T., Takamura, Y., Kita, Y., Watabe, K., Sango, K., Tsuji, S., & Misawa, H. (2018) · PLoS ONE · doi:10.1371/journal.pone.0199829 · Cited by 10

Effects of NDRG1 family proteins on photoreceptor outer segment morphology in zebrafish

Takita, S., Wada, Y., & Kawamura, S. (2016) · Scientific Reports · doi:10.1038/srep36590 · Cited by 9

Ground zero—the airway epithelium

Reid, A. T., Sutanto, E. N., Veerati, P. C., Looi, K., Li, N. F., Iosifidis, T., Loo, S.-L., Garratt, L. W., & Kicic, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816417-4.00003-2 · Cited by 9

Lipoprotein-mediated delivery of BODIPY-labeled sterol and sphingolipid analogs reveals lipid transport mechanisms in mammalian cells

Ikonen, E., & Blom, T. (2015) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2015.08.013 · Cited by 9

Lysosome Associated Protein Transmembrane 4B-24 Is the Predominant Protein Isoform in Human Tissues and Undergoes Rapid, Nutrient-Regulated Turnover

Zhou, K., Dichlberger, A., Ikonen, E., & Blom, T. (2020) · American Journal Of Pathology · doi:10.1016/j.ajpath.2020.07.003 · Cited by 9

Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma

Macsek, P., Skoda, J., Krchniaková, M., Neradil, J., & Veselská, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010376 · Cited by 8

Disruption of Endosomal Sorting in Schwann Cells Leads to Defective Myelination and Endosomal Abnormalities Observed in Charcot-Marie-Tooth Disease

McLean, J. W., Wilson, J. A., Tian, T. M., Watson, J. A., VanHart, M., Bean, A. J., Scherer, S. S., Crossman, D. K., Ubogu, E. E., & Wilson, S. M. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2481-21.2022 · Cited by 8

Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients

Xu, S., Gao, R., Zhou, Y., Yang, Y., Zhang, Y., Li, Q., Luo, C., & Liu, S.-M. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.862216 · Cited by 8

The multiple facets of Rab proteins modulating the cellular distribution of cholesterol from the late endosomal compartment

Nguyen, M. K. L., Pinkenburg, C., Du, J. J., Bernaus‐Esqué, M., Enrich, C., Rentero, C., & Grewal, T. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.119896 · Cited by 7

A splice altering variant in NDRG1 gene causes Charcot-Marie-Tooth disease, type 4D

Pravinbabu, P., Holla, V. V., Phulpagar, P., Kamble, N. L., Netravathi, M., Yadav, R., Pal, P. K., & Muthusamy, B. (2022) · Neurological Sciences · doi:10.1007/s10072-022-05893-4 · Cited by 7

NDRG1 Regulates Iron Metabolism and Inhibits Pathologic Cardiac Hypertrophy

Yuan, J., Yin, C., Peng, H., Fang, G., Mo, B., Qin, X., Chen, Y., Wang, Z., Yu, Y.-C., Wang, Q., et al. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.10.011 · Cited by 6

Dicyclohexyl phthalate derails trophoblast function and lipid metabolism through NDRG1 by targeting PPARα:RXRα

Zhang, Y., Geng, Y., Zhang, Y., Ma, Y., Yin, X. H., Chen, Z., Mu, X., Gao, R., Chen, X., Li, F., et al. (2025) · Toxicology · doi:10.1016/j.tox.2025.154124 · Cited by 5

Re-Shaping the Pancreatic Cancer Tumor Microenvironment: A New Role for the Metastasis Suppressor NDRG1

Chang, J., Lo, Z. H. Y., Alenizi, S., & Kovačević, Ž. (2023) · Cancers · doi:10.3390/cancers15102779 · Cited by 5

Language-Agnostic Reproducible Data Analysis Using Literate Programming

Vassilev, B., Louhimo, R., Ikonen, E., & Hautaniemi, S. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164023 · Cited by 5

Cell and context-dependent sorting of neuropathy-associated protein NDRG1 – insights from canine tissues and primary Schwann cell cultures

Skedsmo, F. S., Tranulis, M. A., Espenes, A., Prydz, K., Matiasek, K., Gunnes, G., Hermansen, L. C., & Jäderlund, K. H. (2019) · BMC Veterinary Research · doi:10.1186/s12917-019-1872-2 · Cited by 5

A case of charcot–marie–Tooth (CMT) disease with hypercholesterolaemia and statin side-effects: A case report and literature review

Maghsoodi, N., & Crook, M. A. (2016) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2016.12.005 · Cited by 5

Aberrant Neuregulin 1/ErbB Signaling in Charcot-Marie-Tooth Type 4D Disease

Jiang, L., Chen, Y., Huang, J., Tong, W., Jin, L., & Li, L.-X. (2022) · Molecular and Cellular Biology · doi:10.1128/mcb.00559-21 · Cited by 4

Di-arginine and FFAT-like motifs retain a subpopulation of PRA1 at ER-mitochondria membrane contact sites

Irqeba, A. A., & Ogilvie, J. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243075 · Cited by 4

Silencing the Signal: The Metastasis Suppressor NDRG1 Disrupts Small Extracellular Vesicle‐Mediated Crosstalk in Pancreatic Cancer

Chang, J., Alenizi, S., Milioli, H. H., Lay, W., Pounraj, S., Li, Y., Sisay, M., Hosseini-Beheshti, E., & Kovačević, Ž. (2026) · Journal of Extracellular Vesicles · doi:10.1002/jev2.70334 · Cited by 2

Niemann-Pick Type C Disease: At the Nexus of Neurodegenerative and Neurodevelopmental Disorders

(2020) · Journal of Parkinson’s Disease and Alzheimer’s Disease · doi:10.13188/2376-922x.1000029 · Cited by 2

Phosphorylation disrupts the interaction between the intrinsically disordered region of the oncogenic NDRG1 and lipid vesicles

Carosella, N., Pastorello, C., Waeytens, J., Beniamino, Y., Roncassaglia, V., Serra, L., Raussens, V., Mileo, E., Ciurli, S., & Zambelli, B. (2026) · Protein Science · doi:10.1002/pro.70510 · Cited by 1

The life and work of Dr. Robert Bittman (1942–2014)

Pyne, N. J., & Kolesnick, R. N. (2014) · Biological Chemistry · doi:10.1515/hsz-2014-0275

A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research

Pyne, N. J., & Tigyi, G. (2015) · Progress in Lipid Research · doi:10.1016/j.plipres.2015.10.003

Studies on Proteins Influencing Cancer Progression and Regulating Endocytic Lipid Trafficking

Vassilev, B. (2017) · Työväentutkimus Vuosikirja

Signalling from Endosomes in Neurodevelopment and Neurodegenerative Disorders

Markworth, R. (2021) · doi:10.53846/goediss-8920

Extracellular vesicle therapeutics: from mechanism to application in cardiac repair

Roefs, M. T. H. F. (2022) · Utrecht University Repository (Utrecht University) · doi:10.33540/1547

Targeting of PYK2 synergizes with EGFR antagonists in basal-like TNBC and circumvents HER3-associated resistance via the NEDD4–NDRG1 axis

Li, T., Lei, C., & Hu, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-821584-5.00018-3

Biomarkers for the early detection and risk stratification in colorectal cancer

Massen, M. (2023) · doi:10.26481/dis.20231213mm

Gene-Based Targeting for Treatment of Hypercholesterolemia and Prevention of Atherosclerotic Cardiovascular Disease

Pollanen, S., & Syan, R. (2024) · Qapsule Queen s Undergraduate Health Sciences Journal · doi:10.24908/qap.v1i2.17347

N-Myc downstream regulated gene 1b is a regulator of cell adhesion during early muscle developmentPreprint

Chowdhary, P. K., & Brewster, R. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.08.652902

Mechanisms of Dysmyelination in Niemann-Pick Type C Disease

Kunkel, T. J. (2023) · Deep Blue (University of Michigan) · doi:10.7302/8224

Additional file 3 of The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Feldt, M., Menard, J. A., Rosendahl, A. H., Lettiero, B., Bendahl, P.-O., Belting, M., & Borgquist, S. (2020) · Figshare · doi:10.6084/m9.figshare.13279076

Additional file 5 of The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Feldt, M., Menard, J. A., Rosendahl, A. H., Lettiero, B., Bendahl, P.-O., Belting, M., & Borgquist, S. (2020) · Figshare · doi:10.6084/m9.figshare.13279082

Additional file 2 of The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Feldt, M., Menard, J. A., Rosendahl, A. H., Lettiero, B., Bendahl, P.-O., Belting, M., & Borgquist, S. (2020) · Figshare · doi:10.6084/m9.figshare.13279073

Additional file 4 of The effect of statin treatment on intratumoral cholesterol levels and LDL receptor expression: a window-of-opportunity breast cancer trial

Feldt, M., Menard, J. A., Rosendahl, A. H., Lettiero, B., Bendahl, P.-O., Belting, M., & Borgquist, S. (2020) · Figshare · doi:10.6084/m9.figshare.13279079

MOLECULAR ADAPTATIONS TO FLUCTUATIONS IN OXYGEN LEVELS

Hufford, T. M. (2023) · Maryland Shared Open Access Repository (USMAI Consortium)

Corrélations génotype/phénotype dans la maladie de Charcot-Marie-Tooth : l'exemple des mutations du gène INF2

Mathis, S. (2014) · theses.fr (ABES) · doi:10.70675/4aa76570z9953z4fcbzb363z8adc3e9ff182

Clinical and pathological findings in two Italian siblings of Romani ancestry with charcot-marie-tooth type 4D and review of the current literature

Abati, E., Aggradi, C. R. F., Magri, S., Pisciotta, C., Balistreri, F., Comi, G., Pareyson, D., Taroni, F., & Corti, S. P. (2026) · Journal of Neuromuscular Diseases · doi:10.1177/22143602261438536

EXPRESS: Reperfusion-sensitive induction of endothelial NDRG1 identifies a dynamic vascular stress response to thrombolysis in ischemic stroke

Furon, J., Etuzé, T., Fosset, L., Goulet, R., Lemarchand, E., Repessé, Y., Vivien, D., & Dubois, F. (2026) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x261501639

IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor

Scotti, E., Calamai, M., Goulbourne, C. N., Zhang, L., Hong, C., Lin, R. R., Choi, J., Pilch, P. F., Fong, L. G., Zou, P., et al. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01716-12 · Cited by 81

Studies on Proteins Influencing Cancer Progression and Regulating Endocytic Lipid Trafficking

Vassilev, B. (2017) · Työväentutkimus Vuosikirja

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

Sorrentino, V., Nelson, J. K., Maspero, E., Marques, A. R. A., Scheer, L., Polo, S., & Zelcer, N. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m037713 · Cited by 68

Ndrg1 in development and maintenance of the myelin sheath

King, R. H. M., Chandler, D., Lopaticki, S., Huang, D., Blake, J. C., Muddle, J. R., Kilpatrick, T. J., Nourallah, M., Miyata, T., Okuda, T., et al. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.01.030 · Cited by 73

Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1

Cianciola, N. L., Greene, D. J., Morton, R. E., & Carlin, C. R. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-10-0760 · Cited by 43