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The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients

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Single-cell transcriptional diversity is a hallmark of developmental potential

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A large-scale binding and functional map of human RNA-binding proteins

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RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

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CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

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Decoding myofibroblast origins in human kidney fibrosis

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Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

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Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

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Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

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Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy

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Aged skeletal stem cells generate an inflammatory degenerative niche

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CHESS: a new human gene catalog curated from thousands of large-scale RNA sequencing experiments reveals extensive transcriptional noise

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The enteric nervous system relays psychological stress to intestinal inflammation

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Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics

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Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

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Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies

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The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

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In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

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Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions

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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

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A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

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The maternal vaginal microbiome partially mediates the effects of prenatal stress on offspring gut and hypothalamus

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Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

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Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

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Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects

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Interferon signaling is diminished with age and is associated with immune checkpoint blockade efficacy in triple-negative breast cancer

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Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning

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Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis

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Molecular hallmarks of heterochronic parabiosis at single-cell resolution

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Molecular characterization of colorectal cancer related peritoneal metastatic disease

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Aging clocks based on accumulating stochastic variation

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LRPPRC-mediated folding of the mitochondrial transcriptome

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HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations

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A tissue injury sensing and repair pathway distinct from host pathogen defense

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Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline

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TEAD Inhibition Overcomes YAP1/TAZ-Driven Primary and Acquired Resistance to KRASG12C Inhibitors

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Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer

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Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin

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CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis

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Medulloblastoma group 3 and 4 tumors comprise a clinically and biologically significant expression continuum reflecting human cerebellar development

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Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy

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Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer

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A mixed community of skin microbiome representatives influences cutaneous processes more than individual members

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Dedifferentiation and neuronal repression define familial Alzheimer’s disease

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A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury

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Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

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Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway

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Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide

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Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

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Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency

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Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells

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LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer

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Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis

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Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

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Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes

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TDP1 splice-site mutation causes HAP1 cell hypersensitivity to topoisomerase I inhibition

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A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation

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Transcriptomic Network Analysis Reveals Trauma Type– and Ancestry-Related Heterogeneity in Posttraumatic Stress Disorder

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Additional file 2 of RNA-Seq transcriptome reveals different molecular responses during human and mouse oocyte maturation and fertilization

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Supplementary Table 4 from Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq

Beane, J., Vick, J. L., Schembri, F. M., et al. (2023) · doi:10.1158/1940-6207.22524410

Supplementary Table 3 from Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq

Beane, J., Vick, J. L., Schembri, F. M., et al. (2023) · doi:10.1158/1940-6207.22524413

Supplementary Table 1 from Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq

Beane, J., Vick, J. L., Schembri, F. M., et al. (2023) · doi:10.1158/1940-6207.22524422.v1

Supplementary Table 10 from Characterizing the Impact of Smoking and Lung Cancer on the Airway Transcriptome Using RNA-Seq

Beane, J., Vick, J. L., Schembri, F. M., et al. (2023) · doi:10.1158/1940-6207.22524419.v1