Ambient ozone pollution and daily mortality: a nationwide study in 272 Chinese cities
Open accessAbstract
BACKGROUND: Few large multicity studies have been conducted in developing countries to address the acute health effects of atmospheric ozone pollution. OBJECTIVE: We explored the associations between ozone and daily cause-specific mortality in China. METHODS: We performed a nationwide time-series analysis in 272 representative Chinese cities between 2013 and 2015. We used distributed lag models and over-dispersed generalized linear models to estimate the cumulative effects of ozone (lagged over 0-3 d) on mortality in each city, and we used hierarchical Bayesian models to combine the city-specific estimates. Regional, seasonal, and demographic heterogeneity were evaluated by meta-regression. RESULTS: increase in 8-h maximum ozone concentration was associated with 0.24% [95% posterior interval (PI): 0.13%, 0.35%], 0.27% (95% PI: 0.10%, 0.44%), 0.60% (95% PI: 0.08%, 1.11%), 0.24% (95% PI: 0.02%, 0.46%), and 0.29% (95% PI: 0.07%, 0.50%) higher daily mortality from all nonaccidental causes, cardiovascular diseases, hypertension, coronary diseases, and stroke, respectively. Associations between ozone and daily mortality due to respiratory and chronic obstructive pulmonary disease specifically were positive but imprecise and nonsignificant. There were no statistically significant differences in associations between ozone and nonaccidental mortality according to region, season, age, sex, or educational attainment. CONCLUSIONS: Our findings provide robust evidence of higher nonaccidental and cardiovascular mortality in association with short-term exposure to ambient ozone in China. https://doi.org/10.1289/EHP1849.
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Short-term exposure to ambient ozone was associated with higher non-accidental and cardiovascular mortality in a large multicity study in China.
“A large multicity study in China showed that short-term exposure to ambient ozone was associated with higher non-accidental and cardiovascular mortality (20).”
From Ozone pollution: A Major health hazard worldwide (2019) · cites this paper as [20]
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- Authors
- Yin, P., Chen, R., Wang, L., Meng, X., Liu, C., Niu, Y., Lin, Z., Liu, Y., Liu, J., Qi, J., You, J., Zhou, M., & Kan, H.
- Affiliations
- Chinese Center For Disease Control and Prevention (CN)
- Fudan University (CN)
- Emory University (US)
- Corresponding author
- Zhou, Maigeng
- Kan, Haidong
- ORCID
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-11
- Volume
- 125
- Issue
- 11
- Pages
- 117006-117006
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC5947936
- OpenAlex
- W2773236687
- Cited by
- 403
- References
- 37
- Citations by year
- 2026: 25 · 2025: 45 · 2024: 60 · 2023: 56 · 2022: 57 · 2021: 53 · 2020: 54 · 2019: 34 · 2018: 18 · 2013: 1
- FWCI
- 15.63
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- Natural Science Foundation of Tibet Autonomous Region
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Keywords
- ambient ozone, air pollution, daily mortality, cardiovascular mortality, stroke, hypertension, coronary artery disease, respiratory mortality, chronic obstructive pulmonary disease, non-accidental mortality, short-term exposure, Chinese cities, developing countries
- MeSH terms
- Air Pollutants, Air Pollution, Cardiovascular Diseases, China, Environmental Exposure, Humans, Mortality, Nitrogen Dioxide, Ozone, Particulate Matter
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