Well-Being and the Risk of Depression under Stress
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Improving our ability to accurately predict individual risk for depression would have profound public health benefits. While there has been growing interest in understanding the relation between measures of positive emotion, such as well-being, and depression, it is not clear whether low well-being is an independent predictor of short term depression risk. We assessed whether low well-being is a risk factor for depressive symptoms. Medical internship is a well-established period of stress when levels of depressive symptoms increase dramatically. 1621 individuals beginning medical internship were assessed for well-being, depressive symptoms, and a set of psychological and demographic traits prior to starting internship year and again for depressive symptoms at 3 month intervals during the year. Low subjective well-being significantly predicted increased depression symptom scores during the stress of medical internship and accounted for individual level inter-variability in depression symptom trends across time. Assessing well-being may have utility in predicting future depression risk.
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Low levels of wellbeing may increase the risk of experiencing mental ill-health over time.
“as evidence suggests that low levels of wellbeing may increase the risk of experiencing mental ill-health over time [116–118].”
From The Mental Health of Elite-Level Coaches: A Systematic Scoping Review (2024) · cites this paper as [117]
Higher levels of psychological well-being buffer against future disorders.
“Higher levels of psychological well-being are associated with better physical health [15] and buffer against future disorders [16, 65], suggesting that people with higher levels are potentially more resilient [66, 67].”
From Can We Increase Psychological Well-Being? The Effects of Interventions on Psychological Well-Being: A Meta-Analysis of Randomized Controlled Trials (2016) · cites this paper as [65]
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- Authors
- Grant, F., Guille, C., & Sen, S.
- Affiliations
- University of Maryland, Baltimore County (US)
- Medical University of South Carolina (US)
- University of Michigan (US)
- Corresponding author
- Sen, Srijan
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2013-07-01
- Volume
- 8
- Issue
- 7
- Pages
- e67395
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3698120
- OpenAlex
- W2059436066
- Cited by
- 189
- References
- 32
- Citations by year
- 2026: 13 · 2025: 13 · 2024: 32 · 2023: 22 · 2022: 23 · 2021: 22 · 2020: 15 · 2019: 14 · 2018: 6 · 2017: 8 · 2016: 13 · 2015: 7 · 2014: 1
- FWCI
- 10.51
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institute of Mental Health (K23MH095109, R01MH101459, MH095109)
- National Institute of General Medical Sciences (R25GM055036)
- National Center for Research Resources (UL1RR024986)
- Topics
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Health Sciences › Health Professions › General Health Professions › Healthcare professionals’ stress and burnout
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- subjective well-being, depression risk, depressive symptoms, stress, medical internship, positive emotions, depression prediction
- MeSH terms
- Adult, Depression, Female, Humans, Male, Personal Satisfaction, Surveys and Questionnaires, Risk Factors, Stress, Psychological
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