Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency

Jami, Elie; White, Bryan A.; Mizrahi, Itzhak

doi:10.1371/journal.pone.0085423

Cited by 592Ruminant Nutrition and Digestive PhysiologyGut microbiota and healthAnimal Nutrition and Physiology

Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency

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Jami, Elie, White, Bryan A., Mizrahi, Itzhak·2014·PLoS ONE

DOI 10.1371/journal.pone.0085423PMC PMC3899005

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Abstract

Ruminants are completely dependent on their microbiota for feed digestion and consequently, their viability. It is therefore tempting to hypothesize a connection between the composition and abundance of resident rumen bacterial taxa and the physiological parameters of the host. Using a pyrosequencing approach, we characterized the rumen bacterial community composition in 15 dairy cows and their physiological parameters. We analyzed the degree of divergence between the different animals and found that some physiological parameters, such as milk yield and composition, are highly correlated with the abundance of various bacterial members of the rumen microbiome. One apparent finding was a strong correlation between the ratio of the phyla Firmicutes to Bacteroidetes and milk-fat yield. These findings paralleled human studies showing similar trends of increased adiposity with an increase in Bacteroidetes. This correlation remained evident at the genus level, where several genera showed correlations with the animals' physiological parameters. This suggests that the bacterial community has a role in shaping host physiological parameters. A deeper understanding of this process may allow us to modulate the rumen microbiome for better agricultural yield through bacterial community design.

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A positive correlation between RFI and the uncultured rumen bacterium RF39 was reported.
“Jami et al. (2014) also reported a positive correlation between RFI and the uncultured rumen bacterium RF39,”
From Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future (2018) · cites this paper as Jami et al., 2014

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I.Mizrahi, “Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency
Jami, E. (2014)
Potential role of rumen bacteria in modulating milk production and composition of admixed dairy cows
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5 Rumen microbiome and metabolome in dairy cattle performance
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Ruminal Bacterial Community Composition in Dairy Cows Is Dynamic over the Course of Two Lactations and Correlates with Feed Efficiency
Jewell, K. A., McCormick, C. A., Odt, C. L., Weimer, P. J., & Suen, G. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.00720-15 · Cited by 281 · see citing works

Authors: Jami, E., White, B. A., & Mizrahi, I.
Affiliations: Tel Aviv University (IL)
University of Illinois Urbana-Champaign (US)
Agricultural Research Organization (IL)
Corresponding author: Mizrahi, Itzhak
ORCID: Jami, Elie
White, Bryan A.
Mizrahi, Itzhak
Venue: PLoS ONE
Publisher: Public Library of Science (PLoS)
Published: 2014-01-22
Volume: 9
Issue: 1
Pages: e85423
ISSN: 1932-6203 (ISSN-L)
DOI: 10.1371/journal.pone.0085423
PMC: PMC3899005
OpenAlex: W2042473229
Cited by: 588
References: 29
Citations by year: 2026: 26 · 2025: 46 · 2024: 78 · 2023: 54 · 2022: 67 · 2021: 82 · 2020: 55 · 2019: 46 · 2018: 38 · 2017: 47 · 2016: 22 · 2015: 20 · 2014: 7
FWCI: 63.79
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: PLoS ONE (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Figshare (submittedVersion, cc-by)
Topics: Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Ruminant Nutrition and Digestive Physiology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
Keywords: rumen microbiome, dairy cattle, milk composition, milk yield, feed efficiency, rumen bacterial community, Firmicutes/Bacteroidetes ratio, milk fat yield, host-microbe interactions, rumen bacteria
MeSH terms: Animals, Animal Feed, Animal Nutritional Physiological Phenomena, Bacteria, Cattle, DNA, Bacterial, Fats, Female, Milk, Phylogeny, RNA, Ribosomal, 16S, Rumen, Sequence Analysis, DNA, Bacteroidetes, Host-Pathogen Interactions, Microbiota

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Potential role of the bovine rumen microbiome in modulating milk composition and feed efficiency

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