Lewy Body Pathology in Alzheimer's Disease

α-Synuclein in Lewy bodies

Spillantini, M. G., Schmidt, M. L., Lee, V. M.-Y., Trojanowski, J. Q., Jakes, R., & Goedert, M. (1997) · Nature · doi:10.1038/42166 · Cited by 8,382 · see citing works

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., et al. (1997) · Science · doi:10.1126/science.276.5321.2045 · Cited by 8,240 · see citing works

Alzheimer's Disease: Genes, Proteins, and Therapy

Selkoe, D. J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.741 · Cited by 6,063 · see citing works

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

Langston, J. W., Ballard, P., Tetrud, J. W., & Irwin, I. (1983) · Science · doi:10.1126/science.6823561 · Cited by 4,914 · see citing works

AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease

Krüger, R., Kuhn, W., Müller, T., Woitalla, D., Graeber, M., Kösel, S., Przuntek, H., Epplen, J. T., Schols, L., & Riess, O. (1998) · Nature Genetics · doi:10.1038/ng0298-106 · Cited by 3,836 · see citing works

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Betarbet, R., Sherer, T., Mackenzie, G., Garcia-Osuna, M., Panov, A., & Greenamyre, J. (2000) · Nature Neuroscience · doi:10.1038/81834 · Cited by 3,797 · see citing works

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6448 · Cited by 3,506 · see citing works

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M., & Goedert, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6469 · Cited by 3,151 · see citing works

Mitochondrial Complex I Deficiency in Parkinson's Disease

Schapira, A. H. V., Cooper, J. M., Dexter, D., Clark, J. B., Jenner, P., & Marsden, C. D. (1990) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1990.tb02325.x · Cited by 2,283 · see citing works

A Drosophila model of Parkinson's disease

Feany, M., & Bender, W. (2000) · Nature · doi:10.1038/35006074 · Cited by 2,145 · see citing works

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

Schapira, A. H. V., Cooper, J. A. D., Dexter, D. T., Jenner, P. G., Clark, J. B., & MARSDEN, C. D. (1989) · The Lancet · doi:10.1016/s0140-6736(89)92366-0 · Cited by 1,757 · see citing works

Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

Masliah, E., Rockenstein, E. M., Veinbergs, I., Mallory, M. E., Hashimoto, M., Takeda, A., Sagara, Y., Sisk, A., & Mucke, L. (2000) · Science · doi:10.1126/science.287.5456.1265 · Cited by 1,752 · see citing works

Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

Abeliovich, A., Schmitz, Y., Fariñas, I., Choi-Lundberg, D., Ho, W.-H., Castillo, P. E., Shinsky, N., Verdugo, J. M. G., Armanini, M., Ryan, A., et al. (2000) · Neuron · doi:10.1016/s0896-6273(00)80886-7 · Cited by 1,722 · see citing works

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

(1998) · Europe PMC (PubMed Central) · Cited by 1,594 · see citing works

Neuropathology of Parkinson's Disease

Forno, L. (1996) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199603000-00001 · Cited by 1,556 · see citing works

Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

Giasson, B. I., Duda, J. E., Murray, I. V. J., Chen, Q., Souza, J. M., Hurtig, H. I., Ischiropoulos, H., Trojanowski, J. Q., & Lee, V. M. ‐. (2000) · Science · doi:10.1126/science.290.5493.985 · Cited by 1,551 · see citing works

NACP, A Protein Implicated in Alzheimer's Disease and Learning, Is Natively Unfolded

Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A., & Lansbury, P. T. (1996) · Biochemistry · doi:10.1021/bi961799n · Cited by 1,524 · see citing works

Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease

Conway, K. A., Harper, J. D., & Lansbury, P. T. (1998) · Nature Medicine · doi:10.1038/3311 · Cited by 1,501 · see citing works

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

Uéda, K., Fukushima, H., Masliah, E., Xia, Y., Iwai, A., Yoshimoto, M., Otero, D. A., Kondo, J. D. M., Ihara, Y., & Saitoh, T. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.23.11282 · Cited by 1,469 · see citing works

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

MCGEER, P., & MCGEER, E. (1995) · Brain Research Reviews · doi:10.1016/0165-0173(95)00011-9 · Cited by 1,287 · see citing works

The Lewy body variant of Alzheimer's disease: A clinical and pathologic entity

Hansen, L., Salmon, D., Galasko, D., Masliah, E., Katzman, R., DeTeresa, R., Thal, L., Pay, M. M., Hofstetter, R., Klauber, M., et al. (1990) · Neurology · doi:10.1212/wnl.40.1.1 · Cited by 1,068 · see citing works

Abnormalities of the electron transport chain in idiopathic parkinson's disease

Parker, W. D., Boyson, S. J., & Parks, J. K. (1989) · Annals of Neurology · doi:10.1002/ana.410260606 · Cited by 1,061 · see citing works

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

Liberatore, G. T., Jackson-Lewis, V., Vukosavic, S., Mandir, A. S., Vila, M., McAuliffe, W. G., Dawson, V. L., Dawson, T. M., & Przedborski, S. (1999) · Nature Medicine · doi:10.1038/70978 · Cited by 1,046 · see citing works

Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

Spillantini, M. G., Crowther, R. A., Jakes, R., Cairns, N. J., Lantos, P. L., & Goedert, M. (1998) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00504-7 · Cited by 1,026 · see citing works

Protofibrillar Intermediates of Amyloid β-Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons

Hartley, D. M., Walsh, D. M., Ye, C., Diehl, T. S., Vasquez, S., Vassilev, P., Teplow, D. B., & Selkoe, D. J. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-20-08876.1999 · Cited by 965 · see citing works

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

Clayton, D. F., & George, J. M. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01213-7 · Cited by 779 · see citing works

Lewy Bodies in Alzheimer's Disease: A Neuropathological Review of 145 Cases Using α‐Synuclein Immunohistochemistry

Hamilton, R. L. (2000) · Brain Pathology · doi:10.1111/j.1750-3639.2000.tb00269.x · Cited by 754 · see citing works

Synucleins Are Developmentally Expressed, and α-Synuclein Regulates the Size of the Presynaptic Vesicular Pool in Primary Hippocampal Neurons

Murphy, D. D., Rueter, S. M., Trojanowski, J. Q., & Lee, V. M. ‐. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-09-03214.2000 · Cited by 753 · see citing works

Review: Alzheimer's Amyloid β-Peptide-Associated Free Radical Oxidative Stress and Neurotoxicity

Varadarajan, S., Yatin, S., Aksenova, M., & Butterfield, D. A. (2000) · Journal of Structural Biology · doi:10.1006/jsbi.2000.4274 · Cited by 735 · see citing works

α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress

Hsu, L. J., Sagara, Y., Arroyo, A., Rockenstein, E. M., Sisk, A., Mallory, M. E., Wong, J., Takenouchi, T., Hashimoto, M., & Masliah, E. (2000) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64553-1 · Cited by 716 · see citing works

Both Familial Parkinson's Disease Mutations Accelerate α-Synuclein Aggregation

Narhi, L. O., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D., Kaufman, S. A., Martin, F. H., Sitney, K. C., Denis, P., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.14.9843 · Cited by 710 · see citing works

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

Tu, P., Galvin, J. E., Baba, M., Giasson, B., Tomita, T., Leight, S., Nakajo, S., Iwatsubo, T., Trojanowski, J. Q., & Lee, V. M. ‐. (1998) · Annals of Neurology · doi:10.1002/ana.410440324 · Cited by 686 · see citing works

Origin and functional consequences of the complex I defect in Parkinson's disease

Swerdlow, R. H., Parks, J. K., Miller, S. W., Davis, R. E., Tuttle, J. B., Trimmer, P. A., Sheehan, J. P., Bennett, J. P., & Parker, W. D. (1996) · Annals of Neurology · doi:10.1002/ana.410400417 · Cited by 638 · see citing works

Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease

Hurtig, H., Trojanowski, J., Galvin, J., Ewbank, D., Schmidt, M., Lee, V., Clark, C., Glosser, G., Stern, M., Gollomp, S., et al. (2000) · Neurology · doi:10.1212/wnl.54.10.1916 · Cited by 596 · see citing works

Dityrosine Cross-linking Promotes Formation of Stable α-Synuclein Polymers

Souza, J. M., Giasson, B. I., Chen, Q., Lee, V. M. ‐., & Ischiropoulos, H. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000206200 · Cited by 561 · see citing works

α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins

Ostrerova, N., Petrucelli, L., Farrer, M. J., Mehta, N., Choi, P., Hardy, J., & Wolozin, B. L. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-14-05782.1999 · Cited by 560 · see citing works

The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity

Golts, N., Petrucelli, L., Hardy, J., Lee, J. M., Farer, M., & Wolozin, B. L. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-16-06048.2000 · Cited by 544 · see citing works

Lewy Bodies Contain Altered α-Synuclein in Brains of Many Familial Alzheimer's Disease Patients with Mutations in Presenilin and Amyloid Precursor Protein Genes

Lippa, C. F., Fujiwara, H., Mann, D. M. A., Giasson, B., Baba, M., Schmidt, M. L., Nee, L. E., O'Connell, B., Pollen, D. A., St. George-Hyslop, P., et al. (1998) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)65722-7 · Cited by 533 · see citing works

β-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease

Mattson, M. P., Barger, S. W., Cheng, B., Lieberburg, I. M., Smith‐Swintosky, V. L., & Rydel, R. E. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90009-b · Cited by 516 · see citing works

Mutant and Wild Type Human α-Synucleins Assemble into Elongated Filaments with Distinct Morphologies in Vitro

Giasson, B. I., Uryu, K., Trojanowski, J. Q., & Lee, V. M. ‐. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.7619 · Cited by 505 · see citing works

Inflammation and Alzheimer's disease pathogenesis

Rogers, J., Webster, S. D., Lue, L., Brachova, L., CIVIN, W. H., Emmerling, M. R., Shivers, B. D., Walker, D. G., & McGeer, P. L. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00115-7 · Cited by 441 · see citing works

Regulation of Phospholipase D2: Selective Inhibition of Mammalian Phospholipase D Isoenzymes by α- and β-Synucleins

Jenco, J. M., Rawlingson, A., Daniels, B., & Morris, A. J. (1998) · Biochemistry · doi:10.1021/bi972776r · Cited by 431 · see citing works

Clinical-Neuropathological Correlations in Alzheimer's Disease and Related Dementias

Galasko, D., Hansen, L. A., Katzman, R., Wiederholt, W. C., Masliah, E., Terry, R. D., Hill, L. R., Lessin, P. J., & Thal, L. J. (1994) · Archives of Neurology · doi:10.1001/archneur.1994.00540210060013 · Cited by 407 · see citing works

Animal Models of Action Tremor

Elble, R. J. (2008) · Movement Disorders · doi:10.1002/mds.870131306 · Cited by 381 · see citing works

A 10-year study of the incidence of and factors predicting dementia in Parkinson’s disease

Hughes, T. A., Ross, H., Musa, S., Bhattacherjee, S., Nathan, R. N., Mindham, R. H. S., & SPOKES, E. G. S. (2000) · Neurology · doi:10.1212/wnl.54.8.1596 · Cited by 368 · see citing works

Ubiquitin carboxyl‐terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases

Lowe, J. S., McDermott, H., Landon, M., Mayer, R. J., & Wilkinson, K. D. (1990) · The Journal of Pathology · doi:10.1002/path.1711610210 · Cited by 359 · see citing works

The Synuclein FamilyPreprint

Lavedan, C. N. (1998) · Genome Research · doi:10.1101/gr.8.9.871 · Cited by 321 · see citing works

Lewy Bodies of Parkinson's Disease Contain Neurofilament Antigens

Goldman, J. E., Yen, S.-H. C., Chiu, F., & Peress, N. S. (1983) · Science · doi:10.1126/science.6308771 · Cited by 260 · see citing works

Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of α‐synuclein protein implicated in Parkinson's disease

El‐Agnaf, O. M. A., Jakes, R., Curran, M. D., & Wallace, A. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)01419-7 · Cited by 258 · see citing works

Membrane Association and Protein Conformation of α-Synuclein in Intact Neurons

McLean, P. J., Kawamata, H., Ribich, S. A., & Hyman, B. T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.8812 · Cited by 243 · see citing works

Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons

Withers, G. S., George, J. M., Banker, G. A., & Clayton, D. F. (1997) · Developmental Brain Research · doi:10.1016/s0165-3806(96)00210-6 · Cited by 235 · see citing works

Effect of the overexpression of wild‐type or mutant α‐synuclein on cell susceptibility to insult

Lee, M., Hyun, D., Halliwell, B. B., & Jenner, P. G. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00149.x · Cited by 232 · see citing works

[Dementia with Lewy bodies].

Martí-Massó, J. F., & Martínez, J. R. (2000) · PubMed · Cited by 231 · see citing works

Plaque-Only Alzheimer Disease is Usually the Lewy Body Variant, and Vice Versa

Hansen, L. A., Masliah, E., Galasko, D., & Terry, R. D. (1993) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199311000-00012 · Cited by 227 · see citing works

The Lewy-Body Variant of Alzheimer's Disease

Förstl, H., Burns, A. S., Luthert, P. J., Cairns, N. J., & Levy, R. (1993) · The British Journal of Psychiatry · doi:10.1192/bjp.162.3.385 · Cited by 221 · see citing works

Immunocytochemical Co-localization of the Proteasome in Ubiquitinated Structures in Neurodegenerative Diseases and the Elderly

Ii, K., Ito, H., Tanaka, K., & Hirano, A. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199702000-00002 · Cited by 215 · see citing works

Wild-type but Not Parkinson's Disease-related Ala-53 → Thr Mutant α-Synuclein Protects Neuronal Cells from Apoptotic Stimuli

da Costa, C. A., Ancolio, K., & Checler, F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002413200 · Cited by 212 · see citing works

Overexpression of human α-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells

Zhou, W., Hurlbert, M. S., Schaack, J. B., Prasad, K. N., & Freed, C. R. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02215-0 · Cited by 204 · see citing works

Enhanced vulnerability to oxidative stress by α-synuclein mutations and C-terminal truncation

Kanda, S., Bishop, J. F., Eglitis, M. A., Yang, Y., & Mouradian, M. M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00077-4 · Cited by 192 · see citing works

Non-Aβ Component of Alzheimer's Disease Amyloid (NAC) Revisited

Culvenor, J. G., McLean, C., Cutt, S., Campbell, B. C. V., Maher, F., Jäkälä, P., Hartmann, T., Beyreuther, K. T., Masters, C. L., & Li, Q. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65220-0 · Cited by 176 · see citing works

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for α-synuclein

Arawaka, S., Saito, Y., Murayama, S., & Mori, H. (1998) · Neurology · doi:10.1212/wnl.51.3.887 · Cited by 172 · see citing works

Expression Pattern of Synucleins (Non‐Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α‐Synuclein) During Murine Brain Development

Hsu, L. J., Mallory, M. E., Xia, Y., Veinbergs, I., Hashimoto, M., Yoshimoto, M., Thal, L. J., Saitoh, T., & Masliah, E. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.71010338.x · Cited by 170 · see citing works

The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases

Schulz, J. B., Matthews, R. T., Klockgether, T., DICHGANS, J., & Beal, M. F. (1997) · Springer eBooks · doi:10.1007/978-1-4615-6111-8_30 · Cited by 170 · see citing works

Induction of neuronal death by α‐synuclein

Saha, R. A., Ninkina, N. N., Hanger, D. P., Anderton, B. H., Davies, A. M., & Buchman, V. L. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00210.x · Cited by 169 · see citing works

Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease.

Iwatsubo, T., Yamaguchi, H., Fujimuro, M., Yokosawa, H., Ihara, Y., Trojanowski, J. Q., & Lee, V. M. (1996) · Europe PMC (PubMed Central) · Cited by 165 · see citing works

Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders

Schmidt, M. L., Martin, J. A., Lee, V. M. ‐., & Trojanowski, J. Q. (1996) · Acta Neuropathologica · doi:10.1007/s004010050454 · Cited by 140 · see citing works

α-Synuclein Immunoreactivity Is Present in Axonal Swellings in Neuroaxonal Dystrophy and Acute Traumatic Brain Injury

Newell, K. L., Boyer, P., Gomez-Tortosa, E., Hobbs, W., Hedley-Whyte, E. T., Vonsattel, J. P., & Hyman, B. T. (1999) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199912000-00007 · Cited by 128 · see citing works

Accumulation of alpha-synuclein in autonomic nerves in pure autonomic failure

Kaufmann, H., Hague, K., & Perl, D. P. (2001) · Neurology · doi:10.1212/wnl.56.7.980 · Cited by 122 · see citing works

Comparison of Lewy body variant of Alzheimer’s disease with pure Alzheimer’s disease

Heyman, A., Fillenbaum, G. G., Gearing, M., Mirra, S. S., Welsh-Bohmer, K. A., Peterson, B. L., & Pieper, C. F. (1999) · Neurology · doi:10.1212/wnl.52.9.1839 · Cited by 109 · see citing works

Pure autonomic failure in association with human α-synucleinopathy

Arai, K., Kato, N., Kashiwado, K., & Hattori, T. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01623-2 · Cited by 108 · see citing works

α-Synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease β-amyloid plaque cores

Bayer, T. A., Jäkälä, P., Hartmann, T., Havas, L., McLean, C., Culvenor, J. G., Li, Q.-X., Masters, C. L., Falkai, P., & Beyreuther, K. T. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00311-0 · Cited by 89 · see citing works

Quantitative neuropathological study of Alzheimer-type pathology in the hippocampus: Comparison of senile dementia of Alzheimer type, senile dementia of Lewy body type, Parkinson's disease and non-demented elderly control patients

Ince, P. G., Irving, D., MacArthur, F., & Perry, R. H. (1991) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(91)90251-2 · Cited by 87 · see citing works

Sensitization of Neuronal Cells to Oxidative Stress with Mutated Human α‐Synuclein

Ko, L., Mehta, N. D., Farrer, M. J., Easson, C., Hussey, J., Yen, S. H., Hardy, J., & Yen, S.-H. C. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0752546.x · Cited by 86 · see citing works

Neuropathological Diagnoses in Elderly Patients in Oslo: Alzheimers Disease, Lewy Body Disease, Vascular Lesions

Ince, P. G., McArthur, F. K., Bjertness, E., TORVIK, A., Candy, J. M., & Edwardson, J. A. (1995) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000106940 · Cited by 78 · see citing works

Predictors of progression in patients with AD and Lewy bodies

López, O. L., Wisniewski, S. R., Hamilton, R. L., Becker, J. T., Kaufer, D., & DeKosky, S. T. (2000) · Neurology · doi:10.1212/wnl.54.9.1774 · Cited by 71 · see citing works

Neural expression profile of α-synuclein in developing human cortex

Bayer, T. A., Jäkälä, P. A., Hartmann, T., et al. (1999) · Neuroreport · doi:10.1097/00001756-199909090-00019 · Cited by 61 · see citing works

Widespread occurrence of α‐synuclein/NACP‐immunoreactive neuronal inclusions in juvenileand adult‐onset Hallervorden–Spatz diseasewith Lewy bodies

Wakabayashi, Yoshimoto, Fukushima, Koide, R., Horikawa, Morita, & Takahashi, Y. (1999) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.1999.00193.x · Cited by 61 · see citing works

Clinical and Neuropathological Correlates of Dementia with Lewy Bodies

Gómez‐Tortosa, E., Irizarry, M. C., Gómez‐Isla, T., & Hyman, B. T. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06899.x · Cited by 59 · see citing works

Dementia with Lewy Bodies

Gómez‐Tortosa, E., Ingraham, A. O., Irizarry, M. C., & Hyman, B. T. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb06016.x · Cited by 44 · see citing works

Intraneuronal filamentous tau protein and α-synuclein deposits in neurodegenerative diseases

Goedert, M., Jakes, R., Crowther, R. A., Hasegawa, M., Smith, M. J., & Spillantini, M. G. (1998) · Biochemical Society Transactions · doi:10.1042/bst0260463 · Cited by 38 · see citing works

The frequency of Lewy bodies in a consecutive autopsy series.

Cf, L., & Hb, H. (1998) · PubMed · Cited by 29 · see citing works

Untitled work

Price (1999) · doi:10.1002/1531-8249(199903)45:3

PROTAC targeted protein degraders: the past is prologue

Békés, M., Langley, D. R., & Crews, C. M. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00371-6 · Cited by 3,395 · see citing works

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

Blennow, K., Hampel, H., Weiner, M., & Zetterberg, H. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.4 · Cited by 1,863 · see citing works

100 years of Lewy pathology

Goedert, M., Spillantini, M. G., Del Tredici, K., & Braak, H. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2012.242 · Cited by 1,190 · see citing works

Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer’s Disease Detected in vivo with Magnetic Resonance Imaging

Raven, E. P., Lu, P. H., Tishler, T. A., Heydari, P., & Bartzokis, G. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-130209 · Cited by 270 · see citing works

Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies

Chang, C.-W., Shao, E., & Mucke, L. (2021) · Science · doi:10.1126/science.abb8255 · Cited by 263 · see citing works

Fluid Biomarkers in Alzheimer Disease

Blennow, K., Zetterberg, H., & Fagan, A. M. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006221 · Cited by 208 · see citing works

Biomarkers used in Alzheimer’s disease diagnosis, treatment, and prevention

Mahaman, Y. A. R., Embaye, K. S., Huang, F., Li, L., Zhu, F., Wang, J.-Z., Liu, R., Feng, J., & Wang, X. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101544 · Cited by 149 · see citing works

Aging and cerebrovascular lesions in pure and in mixed neurodegenerative and vascular dementia brains: a neuropathological study

De Reuck, J., Maurage, C.-A., Deramecourt, V., Pasquier, F., Cordonnier, C., Leys, D., & Bordet, R. (2018) · Folia Neuropathologica · doi:10.5114/fn.2018.76610 · Cited by 84 · see citing works

Cycles of Aberrant Synaptic Sprouting and Neurodegeneration in Alzheimer's and Dementia with Lewy Bodies

Hashimoto, M., & Masliah, E. (2003) · Neurochemical Research · doi:10.1023/a:1026073324672 · Cited by 78 · see citing works

Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels

Deng, P.-Y., & Lei, S. (2008) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2008.07.005 · Cited by 71 · see citing works

Measurements of auto‐antibodies to α‐synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease

Akhtar, R. S., Licata, J. P., Luk, K. C., Shaw, L. M., Trojanowski, J. Q., & Lee, V. M. ‐. (2018) · Journal of Neurochemistry · doi:10.1111/jnc.14330 · Cited by 60 · see citing works

Unsupervised deep learning of electronic health records to characterize heterogeneity across Alzheimer disease and related dementias: cross-sectional study

West, M., Cheng, Y., He, Y., Leng, Y., Magdamo, C., Hyman, B. T., Dickson, J. R., Serrano-Pozo, A., Blacker, D., & Das, S. (2025) · JMIR Aging · doi:10.2196/65178 · Cited by 8 · see citing works

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

(1998) · Europe PMC (PubMed Central) · Cited by 1,594 · see citing works

Differences and similarities between Lewy body dementia and Parkinson's disease dementia

Laar, V. T. (2006) · University of Groningen research database (University of Groningen / Centre for Information Technology)

Quality of Life and the Effect of Memantine in Dementia with Lewy Bodies and Parkinson’s Disease Dementia

Larsson, V., Engedal, K., Aarsland, D., Wattmo, C., Minthon, L., & Londos, E. (2011) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000334523 · Cited by 50 · see citing works

Role of Inflammation in Lewy Body Dementia

Surendranathan, A., & O'Brien, J. T. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.011

Clinical and biochemical correlates of insoluble α-synuclein in dementia with Lewy bodies

Klucken, J., Ingelsson, M., Shin, Y., Irizarry, M. C., Hedley‐Whyte, E. T., Frosch, M. P., Growdon, J. H., McLean, P. J., & Hyman, B. T. (2006) · Acta Neuropathologica · doi:10.1007/s00401-005-0027-7 · Cited by 60 · see citing works