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<i>In Vivo</i>Detection of Age- and Disease-Related Increases in Neuroinflammation by¹⁸F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice

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In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: A PET and MRI study

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Comparative In Vitro and In Vivo Quantifications of Pathologic Tau Deposits and Their Association with Neurodegeneration in Tauopathy Mouse Models

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Evaluation of Microglial Activation in Multiple Sclerosis Patients Using Positron Emission Tomography

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Multimodal Imaging Reveals Temporal and Spatial Microglia and Matrix Metalloproteinase Activity after Experimental Stroke

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PET tracers for the peripheral benzodiazepine receptor and uses thereof

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Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

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Astrocytic TSPO upregulation appears before microglial TSPO in Alzheimer’s disease

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TSPO Finds NOX2 in Microglia for Redox Homeostasis

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TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease

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Characterization and Modeling of the Oligomeric State and Ligand Binding Behavior of Purified Translocator Protein 18 kDa from Rhodobacter sphaeroides

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The mitochondria permeability transition pore complex in the brain with interacting proteins – promising targets for protection in neurodegenerative diseases

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Retinal pigment epithelium cholesterol efflux mediated by the 18 kDa translocator protein, TSPO, a potential target for treating age-related macular degeneration

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Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer

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PET Imaging for Early Detection of Alzheimer’s Disease

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Translocator Protein (TSPO) Role in Aging and Alzheimer’s Disease

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TSPO Ligands Promote Cholesterol Efflux and Suppress Oxidative Stress and Inflammation in Choroidal Endothelial Cells

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PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [18F]PBR06

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Fluorescence-activated cell sorting to reveal the cell origin of radioligand binding

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Neuroinflammation Appears Early on PET Imaging and Then Plateaus in a Mouse Model of Alzheimer Disease

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Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity

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Thalamic neuroinflammation as a reproducible and discriminating signature for chronic low back pain

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Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis

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Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis

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Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors

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Central Nervous System Expression and PET Imaging of the Translocator Protein in Relapsing–Remitting Experimental Autoimmune Encephalomyelitis

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Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging

Shimojo, M., Higuchi, M., Suhara, T., & Sahara, N. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00482 · Cited by 37 · see citing works

Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

Fairley, L. H., Sahara, N., Aoki, I., Ji, B., Suhara, T., Higuchi, M., & Barron, A. M. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02122-1 · Cited by 37 · see citing works

Longitudinal investigation of neuroinflammation and metabolite profiles in the APP swe× PS 1Δe9 transgenic mouse model of Alzheimer's disease

Chaney, A. M., Bauer, M., Bochicchio, D., Smigova, A., Kassiou, M., Davies, K. E., Williams, S. R., & Boutin, H. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14251 · Cited by 37 · see citing works

Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET

Barron, A. M., Tokunaga, M., Zhang, M., Ji, B., Suhara, T., & Higuchi, M. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0700-x · Cited by 36 · see citing works

[18F]-DPA-714 PET as a specific in vivo marker of early microglial activation in a rat model of progressive dopaminergic degeneration

Rodríguez-Chinchilla, T., Quiroga‐Varela, A., Molinet-Dronda, F., Belloso-Iguerategui, A., Merino-Galán, L., Jiménez‐Urbieta, H., Gago, B., & Rodríguez‐Oroz, M. (2020) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-020-04772-4 · Cited by 35 · see citing works

Thalamic neurometabolite alterations in patients with knee osteoarthritis before and after total knee replacement

Weerasekera, A., Morrissey, E. J., Kim, M., Saha, A., Lin, Y., Alshelh, Z., Torrado-Carvajal, Á., Albrecht, D., Akeju, O., Kwon, Y., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002198 · Cited by 33 · see citing works

Molecular imaging of dementia

Mori, T., Maeda, J., Shimada, H., Higuchi, M., Shinotoh, H., Ueno, S., & Suhara, T. (2012) · Psychogeriatrics · doi:10.1111/j.1479-8301.2012.00409.x · Cited by 31 · see citing works

Visualization of Acute Liver Damage Induced by Cycloheximide in Rats Using PET with [18F]FEDAC, a Radiotracer for Translocator Protein (18 kDa)

Hatori, A., Yui, J., Xie, L., Yamasaki, T., Kumata, K., Fujinaga, M., Wakizaka, H., Ogawa, M., Nengaki, N., Kawamura, K., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086625 · Cited by 31 · see citing works

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

Maeda, J., Higuchi, M., Inaji, M., Ji, B., Haneda, E., Okauchi, T., Zhang, M., Suzuki, K., & Suhara, T. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.054 · Cited by 134 · see citing works

The lack of expression of the peripheral benzodiazepine receptor characterises microglial response in anaplastic astrocytomas

Takaya, S., Hashikawa, K., Turkheimer, F., Mottram, N., Deprez, M., Ishizu, K., Kawashima, H., Akiyama, H., Fukuyama, H., Banati, R. B., et al. (2007) · Journal of Neuro-Oncology · doi:10.1007/s11060-007-9396-1 · Cited by 26 · see citing works

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: From pathology to imaging

Venneti, S., Lopresti, B. J., & Wiley, C. A. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.10.002 · Cited by 373 · see citing works

P2–312: PET imaging of microglia in a mouse model of Alzheimer's disease

Venneti, S., Lopresti, B. J., Wang, G., Mathis, C. A., Klunk, W. E., Shmookler, A. D., Hamilton, R. L., Apte, U. M., & Wiley, C. A. (2006) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2006.05.1152

In this Issue - November 15th

(2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.024