In Vivo Positron Emission Tomographic Imaging of Glial Responses to Amyloid-β and Tau Pathologies in Mouse Models of Alzheimer's Disease and Related Disorders

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Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements

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A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss <i>In Vivo</i>

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19F and 1H MRI detection of amyloid β plaques in vivo

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Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography

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Increased Binding of Peripheral Benzodiazepine Receptor in Alzheimer's Disease Measured by Positron Emission Tomography with [11C]DAA1106

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Induction of Inflammatory Mediators and Microglial Activation in Mice Transgenic for Mutant Human P301S Tau Protein

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Quinoline and Benzimidazole Derivatives: Candidate Probes forIn VivoImaging of Tau Pathology in Alzheimer's Disease

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Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies

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Carbon 11–Labeled Pittsburgh Compound B and Carbon 11–Labeled (R)-PK11195 Positron Emission Tomographic Imaging in Alzheimer Disease

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Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: An imaging tool for glial cells in the brain

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Transgenic Mouse Model of Tauopathies with Glial Pathology and Nervous System Degeneration

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Development of a New Radioligand, N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for PET Imaging of Peripheral Benzodiazepine Receptor in Primate Brain

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Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

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The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

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The Positron Emission Tomography Ligand DAA1106 Binds With High Affinity to Activated Microglia in Human Neurological Disorders

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Immunotherapy for Alzheimer's disease

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11C-AC-5216: A Novel PET Ligand for Peripheral Benzodiazepine Receptors in the Primate Brain

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A comparison of the high‐affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)‐PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

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The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: Implications for PET imaging

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Quantitative Analysis of Peripheral Benzodiazepine Receptor in the Human Brain Using PET with11C-AC-5216

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In-vivo visualization of key molecular processes involved in Alzheimer's disease pathogenesis: Insights from neuroimaging research in humans and rodent models

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In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats

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PENN Neurodegenerative Disease Research – In the Spirit of Benjamin Franklin

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Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

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Neuroinflammation as a common feature of neurodegenerative disorders

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Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer’s Disease

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Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

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Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study

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Glial contributions to neurodegeneration in tauopathies

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Tau-targeting therapies for Alzheimer disease: Current status and future directions

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Microglia Function in Alzheimer’s Disease

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Neuroinflammation in Neurodegenerative Disorders-a Review

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High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s and Non-Alzheimer’s Disease Tauopathies

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PET Imaging of Neuroinflammation in Neurological Disorders

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PET Imaging of Inflammation Biomarkers

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Cellular sources of TSPO expression in healthy and diseased brain

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Molecular imaging of microglia/macrophages in the brain

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TSPO in diverse CNS pathologies and psychiatric disease: a critical review and a way forward

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A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

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Neurodegeneration severity can be predicted from early microglia alterations monitoredin vivoin a mouse model of chronic glaucoma

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PET Imaging of Neuroinflammation in Alzheimer’s Disease

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Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study

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Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment–dementia converters measured by positron emission tomography with [11C]DAA1106

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A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

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In-vivo imaging of grey and white matter neuroinflammation in Alzheimer’s disease: a positron emission tomography study with a novel radioligand, [18F]-FEPPA

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Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imaging

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