Perceptual systems controlling speech production
Open accessAbstract
It is proposed that the acquisition and maintenance of fluent speech depend on the rapid temporal integration of motor feedforward and polysensory (auditory and somatosensory) feedback signals. In a functional magnetic resonance imaging study on 21 healthy right-handed, English-speaking volunteers, we investigated activity within these motor and sensory pathways and their integration during speech. Four motor conditions were studied: two speech conditions (propositional and nonpropositional speech) and two silent conditions requiring repetitive movement of the principal articulators (jaw and tongue movements). The scanning technique was adapted to minimize artifact associated with overt speech production. Our result indicates that this multimodal convergence occurs within the left and right supratemporal planes (STPs), with peaks of activity at their posteromedial extents, in regions classically considered as unimodal auditory association cortex. This cortical specialization contrasted sharply with the response of somatosensory association cortex (SII), in which activity was suppressed during speech but not during the silent repetitive movement of the principal articulators. It was also clearly distinct from the response of lateral auditory association cortex, which responded to auditory feedback alone, and from that within a left lateralized ventrolateral temporal and inferior frontal system, which served lexical- and sentence-level language retrieval. This response of cortical regions related to speech production is not predicted by the classical model of hierarchical cortical processing, providing new insights into the role of the STP in polysensory integration and into the modulation of activity in SII during normal speech production. These findings have novel implications for the acquisition and maintenance of fluent speech.
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Posterior medial dorsal surface of superior temporal gyri, including planum temporale, is activated during repetitive (silent) movements of jaw and tongue as well as during auditory feedback and nonspeech vocal tract movements.
“Fifth, the posterior medial dorsal surface of the superior temporal gyri, including the planum temporale, were found to be activated during repetitive (silent) movements of the jaw and tongue as well as during auditory feedback (Dhanjal et al., 2008) and nonspeech vocal tract movements (Loucks et al., 2007).”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Dhanjal et al., 2008
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Cites
Fast robust automated brain extraction
Smith, S. M. (2002) · Human Brain Mapping · doi:10.1002/hbm.10062 · Cited by 10,496 · see citing works
The cortical organization of speech processing
Hickok, G., & Poeppel, D. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2113 · Cited by 5,495 · see citing works
Thresholding of statistical maps in functional neuroimaging using the false discovery rate
Genovese, C. R., Lazar, N. A., & Nichols, T. (2002) · NeuroImage · doi:10.1006/nimg.2001.1037 · Cited by 4,923 · see citing works
A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data
Eickhoff, S. B., Stephan, K. E., Mohlberg, H., Grefkes, C., Fink, G. R., Amunts, K., & Zilles, K. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.12.034 · Cited by 4,033 · see citing works
Hearing Sounds, Understanding Actions: Action Representation in Mirror Neurons
Kohler, E., Keysers, C., Umiltà, M. A., Fogassi, L., Gallese, V., & Rizzolatti, G. (2002) · Science · doi:10.1126/science.1070311 · Cited by 1,801 · see citing works
Birdsong and human speech: common themes and mechanisms
Doupe, A. J., & Kuhl, P. K. (1999) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.22.1.567 · Cited by 1,633 · see citing works
Mechanisms and streams for processing of “what” and “where” in auditory cortex
Rauschecker, J. P., & Tian, B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.22.11800 · Cited by 1,399 · see citing works
MRC psycholinguistic database: Machine-usable dictionary, version 2.00
Wilson, M. (1988) · Behavior Research Methods, Instruments, & Computers · doi:10.3758/bf03202594 · Cited by 1,191 · see citing works
Functional anatomy of a common semantic system for words and pictures
Vandenberghe, R. R., Price, C. J., Wise, R., Josephs, O., & Frackowiak, R. S. J. (1996) · Nature · doi:10.1038/383254a0 · Cited by 1,172 · see citing works
Self-citationNeural modeling and imaging of the cortical interactions underlying syllable production
Guenther, F. H., Ghosh, S. S., & Tourville, J. A. (2006) · Brain and Language · doi:10.1016/j.bandl.2005.06.001 · Cited by 879 · see citing works
Three-Dimensional MRI Atlas of the Human Cerebellum in Proportional Stereotaxic Space
Schmahmann, J. D., Doyon, J., McDonald, D., Holmes, C. J., Lavoie, K., Hurwitz, A. S., Kabani, N. J., Toga, A. W., Evans, A. C., & Petrides, M. (1999) · NeuroImage · doi:10.1006/nimg.1999.0459 · Cited by 782 · see citing works
Auditory-motor interaction revealed by fMRI: speech, music, and working memory in area Spt
Hickok, G., Buchsbaum, B., Humphries, C., & Muftuler, T. (2003) · Journal of Cognitive Neuroscience · doi:10.1162/089892903322307393 · Cited by 700 · see citing works
Functional connectivity in the human language system: a cortico-cortical evoked potential study
Matsumoto, R., Nair, D. R., LaPresto, E., Najm, I., Bingaman, W. E., Shibasaki, H., & Lüders, H. O. (2004) · Brain · doi:10.1093/brain/awh246 · Cited by 677 · see citing works
Separate neural subsystems within ‘Wernicke's area’
Wise, R. J. S., Scott, S. K., Blank, S. C., Mummery, C. J., Murphy, K., & Warburton, E. A. (2001) · Brain · doi:10.1093/brain/124.1.83 · Cited by 572 · see citing works
Self-citationAn fMRI investigation of syllable sequence production
Bohland, J. W., & Guenther, F. H. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2006.04.173 · Cited by 545 · see citing works
Brain regions involved in articulation
Wise, R., Greene, J., Büchel, C., & Scott, S. (1999) · The Lancet · doi:10.1016/s0140-6736(98)07491-1 · Cited by 517 · see citing works
Self-citationNeural substrates of vocalization feedback monitoring in primate auditory cortex
Eliades, S. J., & Wang, X. (2008) · Nature · doi:10.1038/nature06910 · Cited by 479 · see citing works
Buchsbaum, B. R., Hickok, G. S., & Humphries, C. (2001) · Cognitive Science · doi:10.1207/s15516709cog2505_2 · Cited by 469 · see citing works
Modulation of the Auditory Cortex during Speech: An MEG Study
Houde, J. F., Nagarajan, S. S., Sekihara, K., & Merzenich, M. M. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807140 · Cited by 458 · see citing works
Somatosensory input to auditory association cortex in the macaque monkey.
Schroeder, C., Lindsley, R., Specht, C., Marcovici, A., Smiley, J., & Javitt, D. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.3.1322 · Cited by 428 · see citing works
Audiovisual mirror neurons and action recognition
Keysers, C., Kohler, E., Umilt�, M. A., Nanetti, L., Fogassi, L., & Gallese, V. (2003) · Experimental Brain Research · doi:10.1007/s00221-003-1603-5 · Cited by 420 · see citing works
Auditory-Somatosensory Multisensory Processing in Auditory Association Cortex: An fMRI Study
Foxe, J. J., Wylie, G. R., Martı́nez, A., Schroeder, C. E., Javitt, D. C., Guilfoyle, D. N., Ritter, W., & Murray, M. M. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.1.540 · Cited by 419 · see citing works
The Human Parietal Operculum. II. Stereotaxic Maps and Correlation with Functional Imaging Results
Eickhoff, S. B., Amunts, K., Mohlberg, H., & Zilles, K. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhi106 · Cited by 411 · see citing works
Integration of touch and sound in auditory cortex.
Kayser, C., Petkov, C., Augath, M., & Logothetis, N. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.018 · Cited by 404 · see citing works
Foxe, J. J., Mórocz, I. Á., Murray, M. M., Higgins, B. A., Javitt, D. C., & Schroeder, C. E. (2000) · Cognitive Brain Research · doi:10.1016/s0926-6410(00)00024-0 · Cited by 391 · see citing works
Auditory Cortical Neurons Respond to Somatosensory Stimulation
Fu, K., Johnston, T. A., Shah, A., Arnold, L. L., Smiley, J., Hackett, T., Garraghty, P., & Schroeder, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-20-07510.2003 · Cited by 348 · see citing works
Speech production: Wernicke, Broca and beyond
Blank, S. C. (2002) · Brain · doi:10.1093/brain/awf191 · Cited by 342 · see citing works
fMRI reveals two distinct cerebral networks subserving speech motor control
Riecker, A., Mathiak, K., Wildgruber, D., Erb, M., Hertrich, I., Grodd, W., & Ackermann, H. (2005) · Neurology · doi:10.1212/01.wnl.0000152156.90779.89 · Cited by 327 · see citing works
Nonauditory Events of a Behavioral Procedure Activate Auditory Cortex of Highly Trained Monkeys
Brosch, M., Selezneva, E., & Scheich, H. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1571-05.2005 · Cited by 279 · see citing works
Anatomy of the insula functional and clinical correlates
Flynn, F. G. (1999) · Aphasiology · doi:10.1080/026870399402325 · Cited by 271 · see citing works
Neural regions essential for distinct cognitive processes underlying picture naming
Deleon, J., Gottesman, R. F., Kleinman, J. T., Newhart, M., Davis, C. L., Heidler‐Gary, J., Lee, A. H., & Hillis, A. E. (2007) · Brain · doi:10.1093/brain/awm011 · Cited by 263 · see citing works
Paus, T., Perry, D. W., Zatorre, R. J., Worsley, K. J., & Evans, A. C. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01187.x · Cited by 262 · see citing works
Hashimoto, Y., & Sakai, K. L. (2003) · Human Brain Mapping · doi:10.1002/hbm.10119 · Cited by 186 · see citing works
Imaging speech production using fMRI
Gracco, V. L., Tremblay, P., & Pike, G. B. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.01.033 · Cited by 185 · see citing works
Smiley, J. F., Hackett, T. A., Ulbert, I., Karmas, G., Lakatos, P., Javitt, D. C., & Schroeder, C. E. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21325 · Cited by 181 · see citing works
Bayesian inference applied to the electromagnetic inverse problem
Schmidt, D. M., George, J. S., & Wood, C. C. (1999) · Human Brain Mapping · doi:10.1002/(sici)1097-0193(1999)7:3 · Cited by 159 · see citing works
Hackett, T. A., de la Mothe, L. A., Ulbert, I., Karmos, G., Smiley, J. F., & Schroeder, C. E. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21326 · Cited by 152 · see citing works
Cerebral areas associated with motor control of speech in humans
Murphy, K., Corfield, D. R., Guz, A., Fink, G. R., Wise, R. J. S., Harrison, J., & Adams, L. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.5.1438 · Cited by 149 · see citing works
Self-citationEffect of word and syllable frequency on activation during lexical decision and reading aloud
Carreiras, M., Mechelli, A., & Price, C. J. (2006) · Human Brain Mapping · doi:10.1002/hbm.20236 · Cited by 148 · see citing works
Draper, M. H., Ladefoged, P., & Whitteridge, D. (1959) · Journal of Speech and Hearing Research · doi:10.1044/jshr.0201.16 · Cited by 144 · see citing works
A Common System for the Comprehension and Production of Narrative Speech
Awad, M., Warren, J. E., Scott, S. K., Turkheimer, F., & Wise, R. J. S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.5257-06.2007 · Cited by 141 · see citing works
Self-citationRiecker, A., Kassubek, J., Gröschel, K., Grodd, W., & Ackermann, H. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.046 · Cited by 116 · see citing works
Reading, hearing, and the planum temporale
Buchsbaum, B. R., Olsen, R. K., Koch, P. F., Kohn, P. D., Kippenhan, J. S., & Berman, K. F. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.08.025 · Cited by 84 · see citing works
Blakemore, S. (2003) · Consciousness and Cognition · doi:10.1016/j.concog.2003.07.001 · Cited by 72 · see citing works
Afferent cortical connections of the motor cortical larynx area in the rhesus monkey
Simonyan, K., & Jürgens, U. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.08.031 · Cited by 62 · see citing works
Mehta, S., Grabowski, T. J., Razavi, M., Eaton, B., & Bolinger, L. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.039 · Cited by 35 · see citing works
Curio (2000) · doi:10.1002/(sici)1097-0193(200004)9:4
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Research works printed but not linked: 1
- Brett M, Anton JL, Valabregue R, Poline JB (2003) Region of interest anal- ysis using an SPM toolbox [abstract]. Presented at the 8th International Conference on Functional Mapping of the Human Brain, June 2-6, 2002, Sendai, Japan. Available on CD-ROM in Neuroimage, Vol. 16, No. 2, abstract 497.
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Price, C. J. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.04.062 · Cited by 2,159 · see citing works
Beyond the arcuate fasciculus: consensus and controversy in the connectional anatomy of language
Dick, A. S., & Tremblay, P. (2012) · Brain · doi:10.1093/brain/aws222 · Cited by 470 · see citing works
Parker Jones, O., Green, D. W., Grogan, A., Pliatsikas, C., Filippopolitis, K., Ali, N., Lee, H. L., Ramsden, S., Gazarian, K., Prejawa, S., et al. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr161 · Cited by 221 · see citing works
Zheng, Z. Z., Munhall, K. G., & Johnsrude, I. S. (2010) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21324 · Cited by 177 · see citing works
Common neural substrates support speech and non-speech vocal tract gestures
Chang, S.-E., Kenney, M. K., Loucks, T. M. J., Poletto, C. J., & Ludlow, C. L. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.03.032 · Cited by 76 · see citing works
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Agnew, Z. K., McGettigan, C., & Scott, S. K. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00106 · Cited by 59 · see citing works
A comparison of sensory-motor activity during speech in first and second languages
Simmonds, A. J., Wise, R. J. S., Dhanjal, N. S., & Leech, R. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00343.2011 · Cited by 56 · see citing works
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Simmonds, A. J., Wise, R. J. S., & Leech, R. (2011) · Frontiers in Psychology · doi:10.3389/fpsyg.2011.00166 · Cited by 55 · see citing works
Self-citationThe functional specialization of the planum temporale
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Upton, E., Doogan, C., Fleming, V., Leyton, P. Q., Barbera, D., Zeidman, P., Hope, T., Latham, W., Coley-Fisher, H., Price, C., et al. (2024) · eClinicalMedicine · doi:10.1016/j.eclinm.2024.102483 · Cited by 12 · see citing works
- Authors
- Dhanjal, N. S., Handunnetthi, L., Patel, M. C., & Wise, R. J. S.
- Affiliations
- Imperial College London (GB)
- Hammersmith Hospital (GB)
- ORCID
- Handunnetthi, Lahiru
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2008-10-01
- Volume
- 28
- Issue
- 40
- Pages
- 9969-9975
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6671273
- OpenAlex
- W2005513409
- Cited by
- 99
- References
- 47
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 11 · 2014: 11 · 2013: 8 · 2012: 17
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Dunhill Medical Trust
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Phonetics and Phonology Research
- Keywords
- speech production, auditory feedback, somatosensory feedback, somatosensory association cortex, auditory association cortex, articulatory movements, inferior frontal cortex, language acquisition, speech fluency
- MeSH terms
- Adult, Auditory Perception, Brain Mapping, Female, Humans, Jaw, Magnetic Resonance Imaging, Male, Parietal Lobe, Perception, Photic Stimulation, Psychomotor Performance, Speech, Speech Perception, Speech Production Measurement, Temporal Lobe, Tongue
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