Alexander Disease

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., Jin, L., Dykes Hoberg, M., Vidensky, S., Chung, D. S., et al. (2005) · Nature · doi:10.1038/nature03180 · Cited by 1,518

New roles for astrocytes: redefining the functional architecture of the brain.

Nedergaard, M., Ransom, B., & Goldman, S. A. (2003) · Trends in Neurosciences · doi:10.1016/j.tins.2003.08.008 · Cited by 1,334 · cited 1×

A Structural Scaffolding of Intermediate Filaments in Health and Disease

Fuchs, E. V., & Cleveland, D. W. (1998) · Science · doi:10.1126/science.279.5350.514 · Cited by 1,013

Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease

Brenner, M., Johnson, T., Boespflug‐Tanguy, O., Rodriguez, D., Goldman, J. E., & Messing, A. (2001) · Nature Genetics · doi:10.1038/83679 · Cited by 698

The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention

Sheldon, A. L., & Robinson, M. B. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.03.012 · Cited by 593

αB-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

Iwaki, T., Kume-Iwaki, A., Liem, R. K. H., & Goldman, J. E. (1989) · Cell · doi:10.1016/0092-8674(89)90173-6 · Cited by 549

Vesicular release of glutamate from unmyelinated axons in white matter

Ziskin, J. L., Nishiyama, A., Rubio, M. E., Fukaya, M., & Bergles, D. E. (2007) · Nature Neuroscience · doi:10.1038/nn1854 · Cited by 488

Role of plectin in cytoskeleton organization and dynamics

Wiche, G. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.17.2477 · Cited by 423

Astrocytes in the damaged brain: Molecular and cellular insights into their reactive response and healing potential

Buffo, A., Rolando, C., & Ceruti, S. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.09.014 · Cited by 338

Alexander disease: diagnosis with MR imaging.

van der Knaap, M. S., Naidu, S., Breiter, S. N., Blasér, S., Stroink, H., Springer, S., Begeer, J. C., Coster, R. V., Barth, P. G., Thomas, N. H., et al. (2001) · PubMed Central · Cited by 338

Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes

Suga, M., Kondo, T., & Inoue, H. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163862 · Cited by 27

STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease

Hagemann, T. L., Coyne, S., Levin, A., Wang, L., Feany, M. Β., & Messing, A. (2023) · Cells · doi:10.3390/cells12070978 · Cited by 24

Adult-onset Alexander disease, associated with a mutation in an alternative GFAP transcript, may be phenotypically modulated by a non-neutral HDAC6 variant

Melchionda, L., Fang, M., Wang, H., Fugnanesi, V., Morbin, M., Liu, X., Li, W., Ceccherini, I., Farina, L., Savoiardo, M., et al. (2013) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-8-66 · Cited by 24

Glial progenitor cell-based treatment of the childhood leukodystrophies

Osório, M. J., & Goldman, S. A. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.05.010 · Cited by 21

The nature of early astroglial protection—Fast activation and signaling

Kardos, J., Héja, L., Jemnitz, K., Kovács, R., & Palkovits, M. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.03.005 · Cited by 23

Elevated MeCP2 in Mice Causes Neurodegeneration Involving Tau Dysregulation and Excitotoxicity: Implications for the Understanding and Treatment of MeCP2 Triplication Syndrome

Montgomery, K. R., Titus, A. S. C. L. S., Wang, L., & D’Mello, S. R. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1046-4 · Cited by 23

When glia meet induced pluripotent stem cells (iPSCs)

Li, L., & Shi, Y. (2020) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2020.103565 · Cited by 24

Connexins as therapeutic targets in neurological and neuropsychiatric disorders

Charvériat, M., Mouthon, F., Rein, W., & Verkhratsky, A. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166098 · Cited by 22

Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities

Zhang, J., Jinan, Z., & Chen, Y. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-024-06063-0 · Cited by 24

Animal models of leukodystrophy: a new perspective for the development of therapies

Rutherford, H. A., & Hamilton, N. (2019) · FEBS Journal · doi:10.1111/febs.15060 · Cited by 22

Principles of Astrogliopathology

Verkhratsky, A., Li, B., Scuderi, C., & Parpura, V. (2021) · Advances in Neurobiology · doi:10.1007/978-3-030-77375-5_3 · Cited by 21

Astroglial signalling in health and disease

Verkhratsky, A., & Zorec, R. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.07.026 · Cited by 22

GFAP expression is influenced by astrocytoma grade and rs2070935 polymorphism

Sereika, M., Urbanavičiūtė, R., Tamašauskas, A., Skiriutė, D., & Vaitkienė, P. (2018) · Journal of Cancer · doi:10.7150/jca.26769 · Cited by 20

Follow-up study of 22 Chinese children with Alexander disease and analysis of parental origin of de novo GFAP mutations

Zang, L., Wang, J., Jiang, Y., Gu, Q., Gao, Z., Yang, Y., Xiao, J., & Wu, Y. (2013) · Journal of Human Genetics · doi:10.1038/jhg.2012.152 · Cited by 20

Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy

Thompson, J. A., Miralles, R. M., Wengert, E. R., Wagley, P. K., Yu, W., Wenker, I. C., & Patel, M. K. (2021) · Epilepsia Open · doi:10.1002/epi4.12564 · Cited by 19

Proteome of brain glia: The molecular basis of diverse glial phenotypes

Jha, M. K., Kim, J., & Suk, K. (2013) · PROTEOMICS · doi:10.1002/pmic.201300236 · Cited by 19

Discovery of a Small Molecule that Enhances Astrocytogenesis by Activation of STAT3, SMAD1/5/8, and ERK1/2 via Induction of Cytokines in Neural Stem Cells

Lee, H., Farhanullah, Lee, J., Jajoo, R., Kong, S.-Y., Shin, J.-Y., Kim, J., Lee, J., Lee, J., & Kim, H. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00243 · Cited by 20

Neuroglia in Psychiatric Disorders

Scuderi, C., Verkhratsky, A., Parpura, V., & Li, B. (2021) · Advances in neurobiology · doi:10.1007/978-3-030-77375-5_1 · Cited by 19

Neurological and psychiatric disorders as a neuroglial failure.

Verkhratsky, A., & Parpura, V. (2014) · PubMed · Cited by 19

Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

Daniels, C. M. L., Paffenroth, E., Austin, E. V., Glebov, K., Lewis, D., Walter, J., & Messing, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0138132 · Cited by 18

Leukodystrophy imaging: Insights for diagnostic dilemmas.

Thakkar, R. N., Patel, D., Kioutchoukova, I. P., Al-Bahou, R., Reddy, P., Foster, D. T., & Lucke-Wold, B. (2024) · Medical Sciences · doi:10.3390/medsci12010007 · Cited by 17

Familial adult-onset Alexander disease with a novel mutation (D78N) in the glial fibrillary acidic protein gene with unusual bilateral basal ganglia involvement

Wada, Y., Yanagihara, C., Nishimura, Y., & Namekawa, M. (2013) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2013.05.019 · Cited by 17

Type 1 equilibrative nucleoside transporter regulates astrocyte‐specific glial fibrillary acidic protein expression in the striatum

Hinton, D. J., Lee, M. R., Jang, J. S., & Choi, D. (2014) · Brain and Behavior · doi:10.1002/brb3.283 · Cited by 17

Astrocyte Dysfunction in Developmental Neurometabolic Diseases

Olivera‐Bravo, S., Isasi, E., Fernández, A. S., Casanova, G., Rosillo, J. C., & Barbeito, L. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-40764-7_11 · Cited by 15

Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis

Heaven, M. R., Herren, A. W., Flint, D., Pacheco, N. L., Li, J., Tang, A., Khan, F., Goldman, J. E., Phinney, B. S., & Olsen, M. L. (2021) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2021.100180 · Cited by 17

A canine orthologue of the human GFAP c.716G>A (p.Arg239His) variant causes Alexander disease in a Labrador retriever

Poucke, M. V., Martlé, V., Brantegem, L. V., Ducatelle, R., Ham, L. V., Bhatti, S. F. M., & Peelman, L. J. (2015) · European Journal of Human Genetics · doi:10.1038/ejhg.2015.223 · Cited by 16

Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease

Cotrina, M. L., Chen, M. J., Han, X., Iliff, J. J., Ren, Z., Sun, W., Hagemann, T. L., Goldman, J. E., Messing, A., & Nedergaard, M. (2014) · Brain Research · doi:10.1016/j.brainres.2014.07.029 · Cited by 16

Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders

Ahmad, S. R., Zeyaullah, M., AlShahrani, A. M., Dawria, A., Ali, H., Mohieldin, A., Altijani, A. A. G., Razi, U., Mehdi, M., Akram, S., et al. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2904142 · Cited by 15

Astrocytes in the pathophysiology of neuroinfection

Zorec, R., & Verkhratsky, A. (2022) · Essays in Biochemistry · doi:10.1042/ebc20220082 · Cited by 16

A role of astrocytes in mediating postnatal neurodegeneration in Glutaric acidemia‐type 1

Olivera‐Bravo, S., & Barbeito, L. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.09.010 · Cited by 15

Leukodystrophy: Basic and Clinical

Raymond, G. V. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-57193-5_14 · Cited by 15

Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno‐Associated Viral Vector rAAV9P1

Bauer, A., Puglisi, M., Nagl, D., Schick, J., Werner, T. A., Klingl, A., Andari, J. E., Hornung, V., Kessler, H., Götz, M., et al. (2022) · Advanced Science · doi:10.1002/advs.202104979 · Cited by 14

Astrocyte signaling and synaptic homeostasis

Benarroch, E. E. (2016) · Neurology · doi:10.1212/wnl.0000000000003019 · Cited by 14

A mutation in the canine gene encoding folliculin‐interacting protein 2 (FNIP2) associated with a unique disruption in spinal cord myelination

Pemberton, T. J., Choi, S., Mayer, J. A., Li, F., Gokey, N. G., Svaren, J. P., Safra, N., Bannasch, D. L., Sullivan, K., Breuhaus, B. A., et al. (2013) · Glia · doi:10.1002/glia.22582 · Cited by 14

Identification of a novel nonsense mutation in the rod domain of GFAP that is associated with Alexander disease

Nam, T., Kim, J. H., Chang, C.-H., Yoon, W., Jung, Y. S., Kang, S., Shin, B. A., Perng, M., Choi, S., & Kim, M.-K. (2014) · European Journal of Human Genetics · doi:10.1038/ejhg.2014.68 · Cited by 14

Gene and Cellular Therapies for Leukodystrophies

Aerts‐Kaya, F., & van Til, N. P. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15112522 · Cited by 14

Function and regulation of nitric oxide signaling in Drosophila

Jeong, S. (2023) · Molecules and Cells · doi:10.1016/j.mocell.2023.12.004 · Cited by 12

Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer’s disease

Gammie, S. C., Messing, A., Hill, M. A., Kelm‐Nelson, C. A., & Hagemann, T. L. (2024) · PLoS ONE · doi:10.1371/journal.pone.0291995 · Cited by 11

A Putative Role of Teneurin-2 and Its Related Proteins in Astrocytes

Tessarin, G. W. L., Michalec, O. M., Torres-da-Silva, K. R., da Silva, A. V., Cruz-Rizzolo, R. J., Gonçalves, A., Gasparini, D. C., Horta‐Júnior, J. D. A. C., Ervolino, E., Bittencourt, J. C., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00655 · Cited by 10

Anastasis Drives Senescence and Non-Cell Autonomous Neurodegeneration in the Astrogliopathy Alexander Disease

Wang, L., Bukhari, H., Kong, L., Hagemann, T. L., Zhang, S.-C., Messing, A., & Feany, M. Β. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1659-21.2021 · Cited by 11

The Healthy and Diseased Microenvironments Regulate Oligodendrocyte Properties

Leferink, P. S., & Heine, V. M. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.08.030 · Cited by 11

A novel mutation in the GFAP gene expands the phenotype of Alexander disease

Casasnovas, C., Verdura, E., Vélez-Santamaría, V., Schlüter, A., Pons‐Escoda, A., Homedes, C., Ruíz, M., Fourcade, S., Launay, N., & Pujol, A. (2019) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2018-105959 · Cited by 11

Pathological Human Astroglia in Alzheimer's Disease: Opening New Horizons with Stem Cell Technology

Mohamet, L., Jones, V. C., Dayanithi, G., & Verkhratsky, A. (2018) · Future Neurology · doi:10.2217/fnl-2017-0029 · Cited by 11

Genetics behind Cerebral Disease with Ocular Comorbidity: Finding Parallels between the Brain and Eye Molecular Pathology

Chang, K.-J., Wu, H.-Y., Yarmishyn, A. A., Li, C.-Y., Hsiao, Y., Chi, Y., Lo, T.-C., Dai, H.-J., Yang, Y., Liu, D.-H., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179707 · Cited by 9

Transcriptional and Chromatin Accessibility Profiling of Neural Stem Cells Differentiating into Astrocytes Reveal Dynamic Signatures Affected under Inflammatory Conditions

Pavlou, M. A. S., Singh, K., Ravichandran, S., Halder, R., Nicot, N., Birck, C., Grandbarbe, L., del Sol, A., & Michelucci, A. (2023) · Cells · doi:10.3390/cells12060948 · Cited by 11

Astroglia in Leukodystrophies

Jorge, M. S., & Bugiani, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-9913-8_9 · Cited by 11

A Destruction Model of the Vascular and Lymphatic Systems in the Emergence of Psychiatric Symptoms

Segawa, K., Blumenthal, Y., Yamawaki, Y., & Ohtsuki, G. (2021) · Biology · doi:10.3390/biology10010034 · Cited by 11

Atypical MRI features in familial adult onset Alexander disease: case report

Liu, Y., Zhou, H., Wang, H., Gong, X., Zhou, A., Zhao, L., Li, X., & Zhang, X. (2016) · BMC Neurology · doi:10.1186/s12883-016-0734-9 · Cited by 10

Antisense oligonucleotides: A promising advancement in neurodegenerative disease treatment

Dudzisz, K., & Wandzik, I. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177644 · Cited by 9

The spectrum of adult-onset heritable white-matter disorders

Helman, G., Venkateswaran, S., & Vanderver, A. L. (2018) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64076-5.00043-0 · Cited by 9

Modeling and Targeting Neuroglial Interactions with Human Pluripotent Stem Cell Models

Bigarreau, J., Rouach, N., Perrier, A. L., Mouthon, F., & Charvériat, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031684 · Cited by 10

Alexander Disease

Bonthius, D. J., & Karaçay, B. (2015) · Journal of Child Neurology · doi:10.1177/0883073815624762 · Cited by 9

Gfap Mutation and Astrocyte Dysfunction Lead to a Neurodegenerative Profile with Impaired Synaptic Plasticity and Cognitive Deficits in a Rat Model of Alexander Disease

Berman, R. F., Matson, M. R., Bachman, A. M., Lin, N., Coyne, S., Frelka, A., Pearce, R. A., Messing, A., & Hagemann, T. L. (2025) · eNeuro · doi:10.1523/eneuro.0504-24.2025 · Cited by 10

Alexander Disease Modeling in Zebrafish: An In Vivo System Suitable to Perform Drug Screening

Candiani, S., Carestiato, S., Mack, A. F., Bani, D., Bozzo, M., Obino, V., Ori, M., Rosamilia, F., Sarlo, M. D., Pestarino, M., et al. (2020) · Genes · doi:10.3390/genes11121490 · Cited by 8

GFAP variants leading to infantile Alexander disease: Phenotype and genotype analysis of 135 cases and report of a de novo variant

Heshmatzad, K., Panah, M. H., Tavasoli, A. R., Ashrafi, M. R., Mahdieh, N., & Rabbani, B. (2021) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2021.106754 · Cited by 7

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Hagemann, T. L., Sonsalla, M. M., Luzinski, C., Zacahua, F., Harris, D. A., Lamming, D. W., & Messing, A. (2025) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.70209 · Cited by 6

A report of two cases of bulbospinal form Alexander disease and preliminary exploration of the disease

Song, X., Jiang, J., Tian, W., Zhan, F., Zhu, Z., Li, B., Tang, H., & Cao, L. H. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.12211 · Cited by 6

Neuropsychological Functioning in Alexander Disease: A Case Series

Kirsch, A. C., McCall, D. M., Lange, H., Renaud, D. L., Brown, T. M., & Zaccariello, M. J. (2021) · Child Neurology Open · doi:10.1177/2329048x211048614 · Cited by 6

Isolated macrocerebellum: description of six cases and literature review

D’Arco, F., Ugga, L., Caranci, F., Riccio, M. P., Figliuolo, C., Mankad, K., & D’Amico, A. (2016) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims.2016.06.10 · Cited by 6

Type II (adult onset) Alexander disease in a paraplegic male with a rare D128N mutation in the GFAP gene

Chang, K., Pratt, D. W., Mishra, B. B., Edwards, N. A., Hallett, M., & Ray‐Chaudhury, A. (2015) · Clinical Neuropathology · doi:10.5414/np300863 · Cited by 6

Analysis of GFAP variants in UK Biobank suggests underdiagnosis or incomplete penetrance of adult-onset Alexander disease

Gagliardi, D., Wade, C., Tucci, A., Houlden, H., Chataway, J., Barkhof, F., & Lynch, D. S. (2024) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2024-335089 · Cited by 5

General pathophysiology of neuroglia

Verkhratsky, A., Hol, E. M., de Witte, L. D., & Aronica, E. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19102-2.00013-2 · Cited by 6

Glial Fibrillary Acidic Protein as a Marker of Disease in Relapsing Multiple Sclerosis: Post Hoc Analysis of Phase 3 Ozanimod Trials

Harris, S., Comi, G., Cree, B., Arnold, D. L., Steinman, L., Sheffield, J. K., Maddux, R., Southworth, H., Kappos, L., & Cohen, J. A. (2025) · European Journal of Neurology · doi:10.1111/ene.70222 · Cited by 5

A novel in-frame GFAP p.E138_L148del mutation in Type II Alexander disease with atypical phenotypes

Kang, Y., Lee, S., Lin, N., Lee, S., Yang, A., Chandrasekaran, G., Kang, K. W., Jin, M. S., Kim, M., Perng, M., et al. (2022) · European Journal of Human Genetics · doi:10.1038/s41431-022-01073-2 · Cited by 5

Adult-onset Alexander disease among patients of Jewish Syrian descent

Anis, S., Fay‐Karmon, T., Lassman, S., Shbat, F., Lesman‐Segev, O. H., Mor, N., Barel, O., Dominissini, D., Chorin, O., Pras, E., et al. (2023) · Neurogenetics · doi:10.1007/s10048-023-00732-w · Cited by 5

The prion protein is not required for peripheral nerve de- and remyelination after crush injury

Henzi, A., & Aguzzi, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245944 · Cited by 6

Neuroglia in Neurological Diseases

Verkhratsky, A., & Butt, A. M. (2013) · Wiley eBooks · doi:10.1002/9781118402061.ch10 · Cited by 5

Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation

Harit, K., Yi, W., Jeron, A., Schmidt, J., Beckervordersandforth, R., Wyler, E., Manukyan, A., Deckert, M., Radbruch, H., Conrad, T., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65093-4 · Cited by 5

Curing the brain: in search for new astrocyte-specific therapies

Verkhratsky, A., Lee, C. J., Chun, H., Göritz, C., Harkany, T., Lee, J., Lee, S., Lindskog, M., Koh, W., Mulder, J., et al. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-026-01712-4 · Cited by 8

Adult‐onset Alexander disease with unusual inflammatory features and a novel GFAP mutation in two patients

Ziad, F., Cypers, G., Phillips, M. C. L., Vanhoenacker, P. K., Hostens, A., Yadavraj, S., Lamont, D. L., & Robertson, T. (2023) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12927 · Cited by 4

Formes cavitaires de sclérose en plaques : étude multicentrique sur vingt patients

Corlobé, A., Renard, D., Goizet, C., Berger, É., Rumbach, L., Robinson, A. R., Dupuy, D., Touzé, E., Zéphir, H., Vermersch, P., et al. (2013) · Revue Neurologique · doi:10.1016/j.neurol.2013.02.010 · Cited by 4

Identification of association fibers using ex vivo diffusion tractography in Alexander disease brains

Shiohama, T., Stewart, N., Nangaku, M., van der Kouwe, A. J. W., & Takahashi, E. (2022) · Journal of Neuroimaging · doi:10.1111/jon.13040 · Cited by 4

Alexander’s disease and the story of Louise

Wilson, B. A., Vargha‐Khadem, F., & Florschutz, G. (2016) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2016.1222945 · Cited by 4

Cell type-specific isolation and transcriptomic profiling informs glial pathology in human temporal lobe epilepsyPreprint

Tomé-García, J., Nudelman, G., Mussa, Z. M., Caballero, E., Jiang, Y. Y., Beaumont, K. G., Wang, Y., Sebra, R., Akbarian, S., Pinto, D., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.11.421370 · Cited by 4

Iconography of abnormal non-neuronal cells in pediatric focal cortical dysplasia type IIb and tuberous sclerosis complex

Zhang, J., Argueta, D., Tong, X., Vinters, H. V., Mathern, G. W., & Cepeda, C. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1486315 · Cited by 3

Alexander Disease and Astrotherapeutics

Brenner, M., & Messing, A. (2014) · Springer eBooks · doi:10.1007/978-1-4939-0974-2_5 · Cited by 3

A case of Alexander disease presented with dystonia of lower limb and decreased dopaminergic uptake in dopamine transporter scintigraphy

Hayano, E., Shimizu, M., Baba, K., Shimamura, M., Yoshida, T., & Mochizuki, H. (2020) · Rinsho Shinkeigaku · doi:10.5692/clinicalneurol.cn-001445 · Cited by 3

Diagnostic features of type II fibrinoid leukodystrophy (Alexander disease) in a juvenile Beagle dog

Vandenberghe, H., Baiker, K., Nye, G., Escauriaza, L., Roberts, E., Granger, N. P., & Reeve, L. (2023) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.16655 · Cited by 3

Alexander Disease: A Guide for Patients and Families

Messing, A. (2017) · Colloquium Series on Neuroglia in Biology and Medicine From Physiology to Disease · doi:10.4199/c00156ed1v01y201708ngl010 · Cited by 3

Role of Agmatine on Neuroglia in Central Nervous System Injury

Barua, S., Kim, J. Y., & Lee, J. E. (2019) · Brain & Neurorehabilitation · doi:10.12786/bn.2019.12.e2 · Cited by 3

A case of adult onset of Alexander disease with nocturnal painless burns, autonomic dysfunction, and peripheral nerve impairment

Sun, Y., Wang, Z., Li, F., Wei, L., Sun, W. M., Jin, H., Yuan, Y., & Huang, Y. (2020) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2020.106350 · Cited by 3

Neuroglia in leukodystrophies

Hol, E. M., Dykstra, W., Chevalier, J., Cuadrado, E., Bugiani, M., Aronica, E., & Verkhratsky, A. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19102-2.00032-6 · Cited by 3

Pathologic Alexander Disease with Normal GFAP Sequencing: An Autopsy Case Report and Literature Review

Alexander, A. L., Lim, S. Y., Massingham, L. J., Phillips, O. W., Chambers, M., & Donahue, J. E. (2022) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlac086 · Cited by 2

Teaching Neuro Images : Late-onset Alexander disease

Lee, K., Moon, J., & Lee, S. (2014) · Neurology · doi:10.1212/wnl.0000000000001032 · Cited by 2

Degenerative Disorders of the Newborn

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