Cell biology of the mitochondrion

Oxyl radicals, redox-sensitive signalling cascades and antioxidants

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Mitochondrial Fission, Fusion, and Stress

Youle, R. J., & van der Bliek, A. M. (2012) · Science · doi:10.1126/science.1219855 · Cited by 3,674 · see citing works

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082 · see citing works

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Egan, D. F., Shackelford, D. B., Mihaylova, M. M., Gelino, S., Kohnz, R. A., Mair, W., Vasquez, D. S., Joshi, A., Gwinn, D. M., Taylor, R., et al. (2011) · Science · doi:10.1126/science.1196371 · Cited by 2,600 · see citing works

Assessing mitochondrial dysfunction in cells

Brand, M. D., & Nicholls, D. G. (2011) · Biochemical Journal · doi:10.1042/bj20110162 · Cited by 2,436 · see citing works

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

Pickrell, A. M., & Youle, R. J. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.007 · Cited by 2,310 · see citing works

Mitochondrial form and function

Friedman, J. R., & Nunnari, J. (2014) · Nature · doi:10.1038/nature12985 · Cited by 1,803 · see citing works

Production of Reactive Oxygen Species by Mitochondria

Chen, Q., Vazquez, E. J., Moghaddas, S., Hoppel, C. L., & Lesnefsky, E. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304854200 · Cited by 1,616 · see citing works

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

Liesa, M., & Shirihai, O. S. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.002 · Cited by 1,341 · see citing works

RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

Chance, B., & Williams, G. R. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57191-5 · Cited by 1,125 · see citing works

Rates of Behavior and Aging Specified by Mitochondrial Function During Development

Dillin, A., Hsu, A.-L., Arantes-Oliveira, N., Lehrer-Graiwer, J., Hsin, H., Fraser, A. G., Kamath, R. S., Ahringer, J., & Kenyon, C. (2002) · Science · doi:10.1126/science.1077780 · Cited by 1,121 · see citing works

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

Otera, H., Wang, C., Cleland, M. M., Setoguchi, K., Yokota, S., Youle, R. J., & Mihara, K. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201007152 · Cited by 1,110 · see citing works

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

Ryu, D., Mouchiroud, L., Andreux, P. A., Katsyuba, E., Moullan, N., Nicolet-dit-Félix, A. A., Williams, E. G., Jha, P., Lo Sasso, G., Huzard, D., et al. (2016) · Nature Medicine · doi:10.1038/nm.4132 · Cited by 1,105 · see citing works

Metabolic regulation of mitochondrial dynamics

Mishra, P., & Chan, D. C. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201511036 · Cited by 1,096 · see citing works

The Cell Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

Durieux, J., Wolff, S., & Dillin, A. (2011) · Cell · doi:10.1016/j.cell.2010.12.016 · Cited by 1,059 · see citing works

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

Nargund, A. M., Pellegrino, M., Fiorese, C. J., Baker, B. M., & Haynes, C. M. (2012) · Science · doi:10.1126/science.1223560 · Cited by 1,027 · see citing works

Endoplasmic reticulum-mitochondria contacts: Function of the junction

Rowland, A. A., & Voeltz, G. K. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3440 · Cited by 1,018 · see citing works

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

Lee, S. S., Lee, R. Y. N., Fraser, A. G., Kamath, R. S., Ahringer, J., & Ruvkun, G. (2003) · Nature Genetics · doi:10.1038/ng1056 · Cited by 969 · see citing works

Mitochondrial Machineries for Protein Import and Assembly

Wiedemann, N., & Pfanner, N. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060815-014352 · Cited by 894 · see citing works

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor

Wei, Y., Chiang, W., Sumpter, R., Mishra, P., & Levine, B. (2016) · Cell · doi:10.1016/j.cell.2016.11.042 · Cited by 853 · see citing works

Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular Function

Pernas, L. F., & Scorrano, L. (2015) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105011 · Cited by 814 · see citing works

Crystal structure of the entire respiratory complex I

Baradaran, R., Berrisford, J. M., Minhas, G. S., & Sazanov, L. A. (2013) · Nature · doi:10.1038/nature11871 · Cited by 797 · see citing works

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

Palikaras, K., Lionaki, E., & Tavernarakis, N. (2015) · Nature · doi:10.1038/nature14300 · Cited by 770 · see citing works

Dnm1p Gtpase-Mediated Mitochondrial Fission Is a Multi-Step Process Requiring the Novel Integral Membrane Component Fis1p

Mozdy, A. D., McCaffery, J. M., & Shaw, J. M. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.2.367 · Cited by 725 · see citing works

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

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Mitochondrial Electron Transport Is a Key Determinant of Life Span in Caenorhabditis elegans

Feng, J., Bussière, F., & Hekimi, S. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00071-5 · Cited by 675 · see citing works

C. elegans Dynamin-Related Protein DRP-1 Controls Severing of the Mitochondrial Outer Membrane

Labrousse, A. M., Zappaterra, M. D., Rube, D. A., & van der Bliek, A. M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80391-3 · Cited by 670 · see citing works

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

Yang, W., & Hekimi, S. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000556 · Cited by 630 · see citing works

ClpP Mediates Activation of a Mitochondrial Unfolded Protein Response in C. elegans

Haynes, C. M., Petrova, K., Benedetti, C., Yang, Y., & Ron, D. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.07.016 · Cited by 595 · see citing works

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

Van Raamsdonk, J. M., & Hekimi, S. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000361 · Cited by 511 · see citing works

Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission

Rawi, S. A., Louvet‐Vallée, S., Djeddi, A., Sachse, M., Culetto, E., Hajjar, C., Boyd, L., Legouis, R., & Galy, V. (2011) · Science · doi:10.1126/science.1211878 · Cited by 505 · see citing works

Inhibition of mitochondrial fusion by α‐synuclein is rescued by PINK1, Parkin and DJ‐1

Kamp, F., Exner, N., Lutz, A., Wender, N., Hegermann, J., Brunner, B., Nuscher, B., Bartels, T., Giese, A., Beyer, K., et al. (2010) · EMBO Journal · doi:10.1038/emboj.2010.223 · Cited by 505 · see citing works

The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum.

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The matrix peptide exporter HAF-1 signals a mitochondrial unfolded protein response by activating the transcription factor ZC376.7 in C. elegans

Haynes, C. M., Yang, Y., Blais, S., Neubert, T., & Ron, D. (2010) · Molecules and Cells · doi:10.1016/j.molcel.2010.01.015 · Cited by 480 · see citing works

Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos

Sato, M., & Sato, K. (2011) · Science · doi:10.1126/science.1210333 · Cited by 469 · see citing works

Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

Nargund, A. M., Fiorese, C. J., Pellegrino, M. W., Deng, P., & Haynes, C. M. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.02.008 · Cited by 463 · see citing works

Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease

Hsieh, C.-H., Shaltouki, A., Gonzalez, A. E., da Cruz, A. B., Burbulla, L. F., Lawrence, E. S., Schüle, B., Krainc, D., Palmer, T. D., & Wang, X. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.08.002 · Cited by 459 · see citing works

C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

Melentijevic, I., Toth, M. L., Arnold, M. L., Guasp, R. J., Harinath, G., Nguyen, K. C., Taub, D., Parker, J. A., Neri, C., Gabel, C. V., et al. (2017) · Nature · doi:10.1038/nature21362 · Cited by 454 · see citing works

Mitochondrial endonuclease G is important for apoptosis in C. elegans

Parrish, J., Li, L., Klotz, K., Ledwich, D., Wang, X., & Xue, D. (2001) · Nature · doi:10.1038/35083608 · Cited by 427 · see citing works

OPA1 processing in cell death and disease – the long and short of it

MacVicar, T., & Langer, T. (2016) · Journal of Cell Science · doi:10.1242/jcs.159186 · Cited by 420 · see citing works

Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing

Wong, A., Boutis, P., & Hekimi, S. (1995) · Genetics · doi:10.1093/genetics/139.3.1247 · Cited by 416 · see citing works

Role of ANC-1 in Tethering Nuclei to the Actin Cytoskeleton

Starr, D. A., & Han, M. (2002) · Science · doi:10.1126/science.1075119 · Cited by 405 · see citing works

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

Latorre-Pellicer, A., Moreno‐Loshuertos, R., Lechuga‐Vieco, A. V., Sánchez‐Cabo, F., Torroja, C., Acín‐Pérez, R., Calvo, E., Aix, E., González-Guerra, A., Logan, A., et al. (2016) · Nature · doi:10.1038/nature18618 · Cited by 396 · see citing works

C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span

Berdichevsky, A., Viswanathan, M., Horvitz, H. R., & Guarente, L. (2006) · Cell · doi:10.1016/j.cell.2006.04.036 · Cited by 393 · see citing works

Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

Rea, S. L., Ventura, N., & Johnson, T. E. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050259 · Cited by 383 · see citing works

The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

Harbauer, A. B., Zahedi, R. P., Sickmann, A., Pfanner, N., & Meisinger, C. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.01.010 · Cited by 382 · see citing works

Mitochondrial stress induces chromatin reorganization to promote longevity and UPR(mt)

Tian, Y., Garcia, G., Bian, Q., Steffen, K. K., Joe, L., Wolff, S., Meyer, B. J., & Dillin, A. (2016) · Cell · doi:10.1016/j.cell.2016.04.011 · Cited by 370 · see citing works

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

Pellegrino, M. W., Nargund, A. M., Kirienko, N. V., Gillis, R., Fiorese, C. J., & Haynes, C. M. (2014) · Nature · doi:10.1038/nature13818 · Cited by 369 · see citing works

Two conserved histone demethylases regulate mitochondrial stress-induced longevity

Merkwirth, C., Jovaisaite, V., Durieux, J., Matilainen, O., Jordan, S. D., Quiros, P. M., Steffen, K. K., Williams, E. G., Mouchiroud, L., Tronnes, S. U., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.012 · Cited by 363 · see citing works

FUNDC1 regulates mitochondrial dynamics at the ER–mitochondrial contact site under hypoxic conditions

Wu, W., Lin, C., Wu, K., Jiang, L., Wang, X., Li, W., Zhuang, H., Zhang, X., Chen, H. H., Li, S., et al. (2016) · The EMBO Journal · doi:10.15252/embj.201593102 · Cited by 362 · see citing works

The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans

Yee, C., Yang, W., & Hekimi, S. (2014) · Cell · doi:10.1016/j.cell.2014.02.055 · Cited by 356 · see citing works

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells

Suen, D., Narendra, D. P., Tanaka, A., Manfredi, G., & Youle, R. J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914569107 · Cited by 335 · see citing works

Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2

Baker, B. M., Nargund, A. M., Sun, T., & Haynes, C. M. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002760 · Cited by 326 · see citing works

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

Yun, J., Puri, R., Yang, H. M., Lizzio, M. A., Wu, C., Sheng, Z., & Guo, M. (2014) · eLife · doi:10.7554/elife.01958 · Cited by 325 · see citing works

piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling

Huang, H., Gao, Q., Peng, X., Choi, S., Sarma, K., Ren, H., Morris, A. J., & Frohman, M. A. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.01.004 · Cited by 323 · see citing works

Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX

Ney, P. A. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.02.022 · Cited by 319 · see citing works

Structural and Functional Conservation of the Caenorhabditis elegans Timing Gene clk-1

Ewbank, J. J., Barnes, T. M., Lakowski, B., Lussier, M., Bussey, H., & Hekimi, S. (1997) · Science · doi:10.1126/science.275.5302.980 · Cited by 319 · see citing works

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

Jagasia, R., Grote, P., Westermann, B., & Conradt, B. (2005) · Nature · doi:10.1038/nature03316 · Cited by 319 · see citing works

Caenorhabditis elegans pathways that surveil and defend mitochondria

Liu, Y., Samuel, B. S., Breen, P. C., & Ruvkun, G. (2014) · Nature · doi:10.1038/nature13204 · Cited by 309 · see citing works

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

Yamano, K., Fogel, A. I., Wang, C., van der Bliek, A. M., & Youle, R. J. (2014) · eLife · doi:10.7554/elife.01612 · Cited by 307 · see citing works

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

Lin, Y., Schulz, A. M., Pellegrino, M. W., Lu, Y., Shaham, S., & Haynes, C. M. (2016) · Nature · doi:10.1038/nature17989 · Cited by 302 · see citing works

Discovery of Genes Activated by the Mitochondrial Unfolded Protein Response (mtUPR) and Cognate Promoter Elements

Aldridge, J. E., Horibe, T., & Hoogenraad, N. J. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000874 · Cited by 299 · see citing works

Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e / g

Rabl, R., Soubannier, V., Scholz, R., Vogel, F., Mendl, N., Vasiljev, A., Körner, C., Jagasia, R., Keil, T. A., Baumeister, W. P., et al. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200811099 · Cited by 299 · see citing works

Architecture of the mitochondrial calcium uniporter

Oxenoid, K., Dong, Y., Cao, C., Cui, T., Sancak, Y., Markhard, A. L., Grabarek, Z., Kong, L., Liu, Z., OuYang, B., et al. (2016) · Nature · doi:10.1038/nature17656 · Cited by 295 · see citing works

CLK‐1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

Felkai, S., Ewbank, J. J., Lemieux, J., Labbé, J. ‐., Brown, G. G., & Hekimi, S. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.1783 · Cited by 291 · see citing works

Architecture of Active Mammalian Respiratory Chain Supercomplexes

Schäfer, E., Seelert, H., Reifschneider, N. H., Krause, F., Dencher, N. A., & Vonck, J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513525200 · Cited by 289 · see citing works

Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

Hahn, A. S., Parey, K., Bublitz, M., Mills, D. J., Zickermann, V., Vonck, J., Kühlbrandt, W., & Meier, T. W. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.05.037 · Cited by 272 · see citing works

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

Senoo-Matsuda, N., Yasuda, K., Tsuda, M., Ohkubo, T., Yoshimura, S., Nakazawa, H., Hartman, P. S., & Ishii, N. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104718200 · Cited by 271 · see citing works

VDAC isoforms in mammals

Messina, A. A., Reina, S., Guarino, F., & Pinto, V. D. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2011.10.005 · Cited by 269 · see citing works

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

Pfanner, N., van der Laan, M., Amati, P., Capaldi, R., Caudy, A. A., Chacińska, A., Darshi, M., Deckers, M., Hoppins, S. C., Icho, T., et al. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201401006 · Cited by 253 · see citing works

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

Yang, W., & Hekimi, S. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00571.x · Cited by 251 · see citing works

Extension of Life-Span in Caenorhabditis elegans by a Diet Lacking Coenzyme Q

Larsen, P. L., & Clarke, C. F. (2002) · Science · doi:10.1126/science.1064653 · Cited by 249 · see citing works

Mitochondrial dysfunction and longevity in animals: Untangling the knot

Wang, Y., & Hekimi, S. (2015) · Science · doi:10.1126/science.aac4357 · Cited by 248 · see citing works

Cytochrome c Oxidase and the Regulation of Oxidative Phosphorylation

Ludwig, B., Bender, E., Arnold, S., Hüttemann, M., Lee, I., & Kadenbach, B. (2001) · ChemBioChem · doi:10.1002/1439-7633(20010601)2:6 · Cited by 246 · see citing works

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

Kim, H., Scimia, M. C., Wilkinson, D., Dı́az-Trelles, R., Wood, M. R., Bowtell, D. D. L., Dillin, A. G., Mercola, M. A., & Ronai, Z. A. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.045 · Cited by 244 · see citing works

LRRK2 Modulates Vulnerability to Mitochondrial Dysfunction in Caenorhabditis elegans

Saha, S., Guillily, M. D., Ferree, A. W., Lanceta, J., Chan, D., Ghosh, J. G., Hsu, C. H., Segal, L., Raghavan, K., Matsumoto, K., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2281-09.2009 · Cited by 243 · see citing works

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis

Berendzen, K. M., Durieux, J., Shao, L.-W., Tian, Y., Kim, H.-E., Wolff, S., Liu, Y., & Dillin, A. G. (2016) · Cell · doi:10.1016/j.cell.2016.08.042 · Cited by 239 · see citing works

Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response

Kim, H.-E., Grant, A. R., Simic, M., Kohnz, R. A., Nomura, D. K., Durieux, J., Riera, C. E., Sanchez, M., Kapernick, E. A., Wolff, S., et al. (2016) · Cell · doi:10.1016/j.cell.2016.08.027 · Cited by 227 · see citing works

Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor

Herlan, M., Bornhövd, C., Hell, K., Neupert, W., & Reichert, A. S. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200403022 · Cited by 223 · see citing works

A methyl viologen-sensitive mutant of the nematode Caenorhabditis elegans

Ishii, N., Takahashi, K., Tomita, S., Keino, T., Honda, S., Yoshino, K., & Suzuki, K. (1990) · Mutation Research/DNAging · doi:10.1016/0921-8734(90)90022-j · Cited by 213 · see citing works

Mitochondria localize to injured axons to support regeneration

Han, S., Baig, H. S., & Hammarlund, M. (2016) · Neuron · doi:10.1016/j.neuron.2016.11.025 · Cited by 210 · see citing works

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

Shen, Q., Yamano, K., Head, B. P., Kawajiri, S., Cheung, J. T. M., Wang, C., Cho, J.-H., Hattori, N., Youle, R. J., & van der Bliek, A. M. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-09-0525 · Cited by 209 · see citing works

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

Schaar, C. E., Dues, D. J., Spielbauer, K. K., Machiela, E., Cooper, J. F., Senchuk, M., Hekimi, S., & Van Raamsdonk, J. M. (2015) · PLOS Genetics · doi:10.1371/journal.pgen.1004972 · Cited by 203 · see citing works

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

Zhou, Q., Li, H., Li, H., Nakagawa, A., Lin, J. L. J., Lee, E.-S., Harry, B. L., Skeen-Gaar, R. R., Suehiro, Y., William, D., et al. (2016) · Science · doi:10.1126/science.aaf4777 · Cited by 201 · see citing works

Altered Quinone Biosynthesis in the Long-lived clk-1Mutants of Caenorhabditis elegans

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Insight into mitochondrial structure and function from electron tomography

Frey, T., Renken, C. W., & Perkins, G. A. (2002) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(02)00278-5 · Cited by 199 · see citing works

A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants

Jonassen, T., Larsen, P. L., & Clarke, C. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.421 · Cited by 197 · see citing works

Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis

Singhapol, C., Pal, D., Czapiewski, R., Porika, M., Nelson, G., & Saretzki, G. C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0052989 · Cited by 195 · see citing works

Caenorhabditits elegans LRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth

Sämann, J., Hegermann, J., von Gromoff, E. D., Eimer, S., Baumeister, R., & Schmidt, E. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808255200 · Cited by 192 · see citing works

Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response

Runkel, E. D., Liu, S., Baumeister, R., & Schulze, E. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003346 · Cited by 192 · see citing works

Barriers to Male Transmission of Mitochondrial DNA in Sperm Development

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Mitochondrial Genome Content Is Regulated during Nematode Development

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