Vitamin E, Turmeric and Saffron in Treatment of Alzheimer’s Disease

Glutamate neurotoxicity and diseases of the nervous system

Choi, D. W. (1988) · Neuron · doi:10.1016/0896-6273(88)90162-6 · Cited by 8,152 · see citing works

Forecasting the global burden of Alzheimer's disease

Brookmeyer, R., Johnson, E., Ziegler‐Graham, K., & Arrighi, H. M. (2007) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2007.04.381 · Cited by 3,370 · see citing works

Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality

Miller, E. R., Pastor-Barriuso, R., Dalal, D., Riemersma, R. A., Appel, L. J., & Guallar, E. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-1-200501040-00110 · Cited by 2,577 · see citing works

A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease

Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C. W., Pfeiffer, E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704243361704 · Cited by 2,380 · see citing works

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Yang, F., Lim, G. P., Begum, A. N., Ubeda, O. J., Simmons, M. R., Ambegaokar, S. S., Chen, P. P., Kayed, R., Glabe, C. G., Frautschy, S. A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m404751200 · Cited by 2,336 · see citing works

Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention: Systematic Review and Meta-analysis

Bjelakovic, G., Nikolova, D., Gluud, L. L., Simonetti, R. G., & Gluud, C. (2007) · JAMA · doi:10.1001/jama.297.8.842 · Cited by 2,275 · see citing works

Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment

Petersen, R. C., Thomas, R. G., Grundman, M., Bennett, D., Doody, R., Ferris, S., Galasko, D., Jin, S., Kaye, J., Levey, A., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050151 · Cited by 1,844 · see citing works

Alzheimer's Disease and the Amyloid-β Peptide

Murphy, M. P., & LeVine, H. (2010) · Journal of Alzheimer's Disease · doi:10.3233/jad-2010-1221 · Cited by 1,750 · see citing works

Vitamin E: function and metabolism

Brigelius‐Flohé, R., & Traber, M. G. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.10.1145 · Cited by 1,593 · see citing works

The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse

Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., & Cole, G. M. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-21-08370.2001 · Cited by 1,530 · see citing works

Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro

Ono, K., Hasegawa, K., Naiki, H., & Yamada, M. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20025 · Cited by 1,254 · see citing works

Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress

Butterfield, D. A., & Lauderback, C. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00794-3 · Cited by 999 · see citing works

Linking lipids to Alzheimer's disease: cholesterol and beyond

Di Paolo, G., & Kim, T.-W. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3012 · Cited by 972 · see citing works

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

Zhao, Y., & Zhao, B. (2013) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2013/316523 · Cited by 855 · see citing works

Tocotrienols: Vitamin E beyond tocopherols

Sen, C. K., Khanna, S., & Roy, S. (2006) · Life Sciences · doi:10.1016/j.lfs.2005.12.001 · Cited by 730 · see citing works

Curcumin labels amyloid pathology in vivo , disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model

Garcı́a-Alloza, M., Borrelli, L. A., Rozkalne, A., Hyman, B. T., & Bacskai, B. J. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04613.x · Cited by 663 · see citing works

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial

Dysken, M. W., Sano, M., Asthana, S., Vertrees, J. E., Pallaki, M., Llorente, M., Love, S., Schellenberg, G. D., McCarten, J. R., Malphurs, J., et al. (2014) · JAMA · doi:10.1001/jama.2013.282834 · Cited by 628 · see citing works

Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification

Morris, M. S., Jacques, P. F., Rosenberg, I. H., & Selhub, J. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.1.193 · Cited by 607 · see citing works

Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice

Hosseinzadeh, H., & Younesi, H. M. (2002) · BMC Pharmacology · doi:10.1186/1471-2210-2-7 · Cited by 606 · see citing works

Oxidative stress in the progression of Alzheimer disease in the frontal cortex

Ansari, M. A., & Scheff, S. W. (2010) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3181cb5af4 · Cited by 605 · see citing works

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer’s Disease

Begum, A. N., Jones, M. R., Lim, G. P., Morihara, T., Kim, P., Heath, D. D., Rock, C. L., Pruitt, M. A., Yang, F., Hudspeth, B., et al. (2008) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.137455 · Cited by 604 · see citing works

The effect of curcumin (turmeric) on Alzheimer’s disease: An overview

Mishra, S., & Palanivelu, K. (2008) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.40220 · Cited by 599 · see citing works

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

Aisen, P. S. S. (2008) · JAMA · doi:10.1001/jama.300.15.1774 · Cited by 557 · see citing works

A Potential Role of the Curry Spice Curcumin in Alzheimers Disease

Ringman, J. M., Frautschy, S. A., Cole, G. M., Masterman, D. L., & Cummings, J. L. (2005) · Current Alzheimer Research · doi:10.2174/1567205053585882 · Cited by 519 · see citing works

Homocysteine and folate as risk factors for dementia and Alzheimer disease

Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Porcellini, E., & Licastro, F. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.3.636 · Cited by 500 · see citing works

Homocysteine and folate as risk factors for dementia and Alzheimer disease

Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Porcellini, E., & Licastro, F. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.3.636 · Cited by 500 · see citing works

Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer’s disease animal models

Baum, L., & Ng, A. (2004) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6403 · Cited by 483 · see citing works

Oxidative stress in Alzheimer disease

Gella, A., & Durany, N. (2009) · Cell Adhesion & Migration · doi:10.4161/cam.3.1.7402 · Cited by 459 · see citing works

Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes

(1992) · doi:10.1007/bf00229582 · Cited by 458 · see citing works

Alzheimer Disease and Oxidative Stress

Perry, G., Cash, A. D., & Smith, M. A. (2002) · BioMed Research International · doi:10.1155/s1110724302203010 · Cited by 455 · see citing works

Vitamin E for Alzheimer's dementia and mild cognitive impairment

Farina, N., Llewellyn, D. J., Isaac, M. G. E. K. N., & Tabet, N. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002854.pub5 · Cited by 421 · see citing works

Neuroprotective strategies involving ROS in Alzheimer disease

Dumont, M., & Beal, M. F. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.11.026 · Cited by 402 · see citing works

The Role of Insulin Resistance in the Pathogenesis of Alzheimer??s Disease

Watson, G. S., & Craft, S. (2003) · CNS Drugs · doi:10.2165/00023210-200317010-00003 · Cited by 396 · see citing works

The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E

Wefers, H., & Sies, H. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14105.x · Cited by 389 · see citing works

Antioxidant Therapies for Alzheimer's Disease

Feng, Y., & Wang, X. (2012) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2012/472932 · Cited by 382 · see citing works

Curry Consumption and Cognitive Function in the Elderly

Ng, T. P., Chiam, P., Lee, T. M., Chua, H.-C., Lim, L. E. C., & Kua, E. H. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj267 · Cited by 353 · see citing works

High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study

Tucker, K. L., Qiao, N., Scott, T. M., Rosenberg, I. H., & Spiro, A. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.3.627 · Cited by 351 · see citing works

High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study

Tucker, K. L., Qiao, N., Scott, T., Rosenberg, I., & Spiro, A. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.3.627 · Cited by 351 · see citing works

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis

Schrag, M., Mueller, C., Zabel, M. K., Crofton, A. R., Kirsch, W. M., Ghribi, O., Squitti, R., & Perry, G. L. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.07.005 · Cited by 335 · see citing works

Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease

Baranello, R., Bharani, K., Padmaraju, V., Chopra, N., Lahiri, D., Greig, N., Pappolla, M., & Sambamurti, K. (2015) · Current Alzheimer Research · doi:10.2174/1567205012666141218140953 · Cited by 331 · see citing works

Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?

Persson, T., Popescu, B. O., & Cedazo-Mı́nguez, Á. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/427318 · Cited by 318 · see citing works

Curcumin Suppresses Janus Kinase-STAT Inflammatory Signaling through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia

Kim, H. Y., Park, E. J., Joe, E.-H., & Jou, I. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.11.6072 · Cited by 313 · see citing works

Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change

Morris, M. C., Evans, D. A., Tangney, C. C., Bienias, J. L., Wilson, R. S., Aggarwal, N. T., & Scherr, P. A. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn.81.2.508 · Cited by 302 · see citing works

Protective effects of saffron extract and its active constituent crocin against oxidative stress and spatial learning and memory deficits induced by chronic stress in rats

Ghadrdoost, B., Vafaei, A. A., Rashidy‐Pour, A., Hajisoltani, R., Bandegi, A. R., Motamedi, F., Haghighi, S., Sameni, H. R., & Pahlvan, S. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.05.012 · Cited by 295 · see citing works

Incidence of Alzheimer’s disease in a rural community in India

Chandra, V., Pandav, R. S., Dodge, H. H., Johnston, J. M., Belle, S. H., DeKosky, S. T., & Ganguli, M. (2001) · Neurology · doi:10.1212/wnl.57.6.985 · Cited by 283 · see citing works

Dietary Antioxidants and Long-term Risk of Dementia

Devore, E. E., Grodstein, F., van Rooij, F. J. A., Albert Hofman, D., Stampfer, M. J., Witteman, J. C. M., & Breteler, M. M. B. (2010) · Archives of Neurology · doi:10.1001/archneurol.2010.144 · Cited by 277 · see citing works

Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers.

Soni, K. B., & Kuttan, R. (1992) · PubMed · Cited by 276 · see citing works

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment

Markesbery, W. R., Kryscio, R. J., Lovell, M. A., & Morrow, J. D. (2005) · Annals of Neurology · doi:10.1002/ana.20629 · Cited by 272 · see citing works

Importance of Iron Chelation in Free Radical-Induced Oxidative Stress and Human Disease

Jomová, K., & Valko, M. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211798072463 · Cited by 271 · see citing works

Aβ and Tau Toxicities in Alzheimer's Are Linked via Oxidative Stress-Induced P38 Activation: Protective Role of Vitamin E

Giraldo, E., Lloret, A., Fuchsberger, T., & Viña, J. (2014) · Redox Biology · doi:10.1016/j.redox.2014.03.002 · Cited by 268 · cited 2× · see citing works

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

Akhondzadeh, S., Shafiee Sabet, M., Harirchian, M. H., Togha, M., Cheraghmakani, H., Razeghi, S., Hejazi, S. S., Yousefi, M. H., Alimardani, R., Jamshidi, A., et al. (2010) · Psychopharmacology · doi:10.1007/s00213-009-1706-1 · Cited by 268 · see citing works

Associations Between Serum Cholesterol Levels and Cerebral Amyloidosis

Reed, B., Villeneuve, S., Mack, W., DeCarli, C., Chui, H. C., & Jagust, W. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2013.5390 · Cited by 267 · see citing works

The Antioxidant Functions of Tocopherol and Tocotrienol Homologues in Oils, Fats, and Food Systems

Seppanen, C. M., Song, Q., & Csallany, A. S. (2010) · Journal of the American Oil Chemists Society · doi:10.1007/s11746-009-1526-9 · Cited by 251 · see citing works

Diverse effects of a low dose supplement of lipidated curcumin in healthy middle aged people

DiSilvestro, R. A., Joseph, E., Zhao, S., & Bomser, J. A. (2012) · Nutrition Journal · doi:10.1186/1475-2891-11-79 · Cited by 244 · see citing works

Vitamin E Prevents Alzheimer's Amyloid ß-Peptide (1-42)-Induced Neuronal Protein Oxidation and Reactive Oxygen Species Production

Yatin, S. M., Varadarajan, S., & Butterfield, D. A. (2000) · Journal of Alzheimer s Disease · doi:10.3233/jad-2000-2212 · Cited by 239 · see citing works

Peripheral Oxidative Stress Biomarkers in Mild Cognitive Impairment and Alzheimer's Disease

Torres, L. H., Quaglio, N. B., de Souza, G. T., Garcia, R. C. T., Dati, L. M. M., Moreira, W. L., Loureiro, A. P. D. M., Souza‐Talarico, J. N., Smid, J., Porto, C. S., et al. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-110284 · Cited by 235 · see citing works

Antioxidants as therapeutic agents for liver disease

Singal, A. K., Jampana, S. C., & Weinman, S. A. (2011) · Liver International · doi:10.1111/j.1478-3231.2011.02604.x · Cited by 234 · see citing works

Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin

Fiala, M., Liu, P. T., Monteros, A. E. D. L., Rosenthal, M. J., Bernard, G. W., Ringman, J. M., Sayre, J. W., Zhang, L., Zaghi, J., Dejbakhsh, S., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701267104 · Cited by 233 · see citing works

A Randomized Trial of Vitamin E Supplementation and Cognitive Function in Women

Kang, J. H. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.22.2462 · Cited by 226 · see citing works

Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women

Princen, H. M. G., van Duyvenvoorde, W., Buytenhek, R., van der Laarse, A., van Poppel, G., Leuven, J. A. G., & van Hinsbergh, V. W. M. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.3.325 · Cited by 222 · see citing works

Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood–brain barrier damage

Jiang, J., Wang, W., Sun, Y. J., Hu, M. Y., Li, F., & Zhu, D. Y. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.12.028 · Cited by 222 · see citing works

Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation

Bast, A., & Haenen, G. R. M. M. (1988) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(88)90326-8 · Cited by 217 · see citing works

Metal Chelation as a Potential Therapy for Alzheimer's Disease

Cuajungco, M. P., Faget, K. Y., Huang, X., Tanzi, R. E., & Bush, A. I. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06938.x · Cited by 215 · see citing works

Iron chelation in the biological activity of curcumin

Jiao, Y., Wilkinson, J. C., Pietsch, E. C., Buss, J. L., Wang, W., Planalp, R. P., Torti, F. M., & Torti, S. V. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.11.003 · Cited by 211 · see citing works

Vitamin E and All-Cause Mortality: A Meta-Analysis

L. Abner, E., A. Schmitt, F., S. Mendiondo, M., L. Marcum, J., & J. Kryscio, R. (2011) · Current Aging Sciencee · doi:10.2174/1874609811104020158 · Cited by 209 · see citing works

Vitamin B 12 status and rate of brain volume loss in community-dwelling elderly

Vogiatzoglou, A., Refsum, H., Johnston, C., Smith, S. M., Bradley, K. M., de Jager, C., Budge, M. M., & Smith, A. D. (2008) · Neurology · doi:10.1212/01.wnl.0000325581.26991.f2 · Cited by 192 · see citing works

Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies

Swomley, A. M., Förster, S., Keeney, J. T. R., Triplett, J. C., Zhang, Z., Rukhsana Sultana, A., & Butterfield, D. A. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.09.015 · Cited by 190 · see citing works

Saffron as a Source of Novel Acetylcholinesterase Inhibitors: Molecular Docking and in Vitro Enzymatic Studies

Geromichalos, G. D., Lamari, F. N., Papandreou, M. A., Trafalis, D. T., Margarity, M., Papageorgiou, T., & Sinakos, Z. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf300589c · Cited by 189 · see citing works

β ‐Amyloid Degradation and Alzheimer′s Disease

Wang, D.-S., Dickson, D. W., & Malter, J. S. (2006) · BioMed Research International · doi:10.1155/jbb/2006/58406 · Cited by 185 · see citing works

Curcuminoids enhance amyloid-β uptake by macrophages of Alzheimer's disease patients

Zhang, L., Fiala, M., Cashman, J. R., Sayre, J. W., Monteros, A. E. D. L., Mahanian, M., Zaghi, J., Badmaev, V., Graves, M. C., Bernard, G. W., et al. (2006) · Journal of Alzheimer s Disease · doi:10.3233/jad-2006-10101 · Cited by 183 · see citing works

Effects of Vitamin E on Cognitive Performance during Ageing and in Alzheimer’s Disease

Fata, G. L., Weber, P., & Mohajeri, M. H. (2014) · Nutrients · doi:10.3390/nu6125453 · Cited by 174 · see citing works

High Plasma Levels of Vitamin E Forms and Reduced Alzheimer's Disease Risk in Advanced Age

Mangialasche, F., Kivipelto, M., Mecocci, P., Rizzuto, D., Palmer, K., Winblad, B. G., & Fratiglioni, L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091450 · Cited by 172 · see citing works

Modulation of signal transduction by vitamin E

Zingg, J.-M. A. (2007) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2006.12.009 · Cited by 170 · see citing works

Alzheimer's disease: the pros and cons of pharmaceutical, nutritional, botanical, and stimulatory therapies, with a discussion of treatment strategies from the perspective of patients and practitioners.

Wollen, K. A. (2010) · PubMed · Cited by 168 · see citing works

Vitamin E and Cardiovascular Disease

Saremi, A., & Arora, R. R. (2010) · American Journal of Therapeutics · doi:10.1097/mjt.0b013e31819cdc9a · Cited by 166 · see citing works

Cholesterol as a risk factor for Alzheimer's disease - epidemiological evidence

Kivipelto, M., & Solomon, A. (2006) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2006.00685.x · Cited by 165 · see citing works

Iron dysregulation in Alzheimer's disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents

Mandel, S., Amit, T., Bar-Am, O., & Youdim, M. B. H. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.06.001 · Cited by 164 · see citing works

Peripheral Oxidative Damage in Mild Cognitive Impairment and Mild Alzheimer's Disease

Baldeiras, I., Santana, I. J., Proença, M. T., Garrucho, M. H., Pascoal, R., Rodrigues, A. P., Duro, D., & Oliveira, C. R. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-15110 · Cited by 157 · see citing works

Bioavailability of vitamin E in humans: an update

Borel, P., Prévéraud, D. P., & Desmarchelier, C. (2013) · Nutrition Reviews · doi:10.1111/nure.12026 · Cited by 157 · see citing works

Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients

Wood, P. L., Mankidy, R., Ritchie, S. A., Heath, D., Wood, J. A., Flax, J., & Goodenowe, D. B. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090059 · Cited by 157 · see citing works

Curcumin, the active constituent of turmeric, inhibits amyloid peptide‐induced cytochemokine gene expression and CCR5‐mediated chemotaxis of THP‐1 monocytes by modulating early growth response‐1 transcription factor

Giri, R. K., Rajagopal, V., & Kalra, V. K. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02800.x · Cited by 143 · see citing works

The Roles of Biomarkers of Oxidative Stress and Antioxidant in Alzheimer’s Disease: A Systematic Review

Chang, Y., Chang, W., Tsai, N., Huang, C., Kung, C., Su, Y., Lin, W.-C., Cheng, B., Su, C.-M., Chiang, Y.-F., et al. (2014) · BioMed Research International · doi:10.1155/2014/182303 · Cited by 143 · see citing works

Therapeutic Potential of Turmeric in Alzheimer's Disease: Curcumin or Curcuminoids?

Ahmed, T., & Gilani, A. H. (2013) · Phytotherapy Research · doi:10.1002/ptr.5030 · Cited by 141 · see citing works

Cholesterol in Alzheimers Disease: Unresolved Questions

Stefani, M., & Liguri, G. (2009) · Current Alzheimer Research · doi:10.2174/156720509787313899 · Cited by 134 · see citing works

Vitamin E for Alzheimer's disease and mild cognitive impairment

Isaac, M. G. E. K. N., Quinn, R., & Tabet, N. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002854.pub2 · Cited by 131 · see citing works

Protective role of supplemental vitamin E on lipid peroxidation, vitamins E, A and some mineral concentrations of broilers reared under heat stress

Şahin, K., Şahin, N., Önderci, M., et al. (2001) · Veterinární Medicína · doi:10.17221/7870-vetmed · Cited by 124 · see citing works

Alzheimer's Disease is Incurable but Preventable

de la Torre, J. C. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-091579 · Cited by 123 · see citing works

Curcumin Attenuates Iron Accumulation and Oxidative Stress in the Liver and Spleen of Chronic Iron-Overloaded Rats

Badria, F., Ibrahim, A., Badria, A., & Elmarakby, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0134156 · Cited by 121 · see citing works

Antioxidant activity of aqueous and ethanolic extracts of Crocus sativus L. stigma and its bioactive constituents, crocin and safranal

Hosseinzadeh, H., Shamsaie, F., & Mehri, S. (2009) · Pharmacognosy Magazine · Cited by 116 · see citing works

Plasmalogen synthesis is regulated via alkyl‐dihydroxyacetonephosphate‐synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease

Grimm, M. O. W., Kuchenbecker, J., Rothhaar, T. L., Grösgen, S., Hundsdörfer, B., Burg, V. K., Frieß, P., Müller, U., Grimm, H. S., Riemenschneider, M. J., et al. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07070.x · Cited by 115 · see citing works

Effects of turmeric on Alzheimer′s disease with behavioral and psychological symptoms of dementia

Hishikawa, N., Takahashi, Y., Amakusa, Y., Tanno, Y., Tuji, Y., Niwa, H., Murakami, N., & Krishna, U. (2012) · AYU (An International Quarterly Journal of Research in Ayurveda) · doi:10.4103/0974-8520.110524 · Cited by 115 · see citing works

Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat.

Suryanarayana, P., Satyanarayana, A., Balakrishna, N., Kumar, P. U., & Reddy, G. B. (2007) · PubMed · Cited by 114 · see citing works

Curcumin as a Therapeutic Agent in Dementia: A Mini Systematic Review of Human Studies

Brondino, N., Re, S., Boldrini, A., Cuccomarino, A. F., Lanati, N., Barale, F., & Politi, P. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/174282 · Cited by 99 · see citing works

Is High Homocysteine Level a Risk Factor for Cognitive Decline in Elderly? A Systematic Review, Meta-Analysis, and Meta-Regression

Ho, R. C. M., Cheung, M. W. L., Fu, E., Win, H. H., Zaw, M. H., Ng, A., & Mak, A. (2011) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181f17eed · Cited by 99 · see citing works

Effect of One-Year Vitamin C- and E-Supplementation on Cerebrospinal Fluid Oxidation Parameters and Clinical Course in Alzheimer’s Disease

Arlt, S., Müller‐Thomsen, T., Beisiegel†, U., & Kontush, A. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0860-8 · Cited by 98 · see citing works

Do free radicals play causal role in atherosclerosis? Low density lipoprotein oxidation and vitamin E revisited

Niki, E. (2010) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.11-007fr · Cited by 94 · see citing works

Vitamin E in aging, dementia, and Alzheimer's disease

Joshi, Y. B., & Praticò, D. (2012) · BioFactors · doi:10.1002/biof.195 · Cited by 92 · see citing works

Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression

Bradley‐Whitman, M. A., Xiong, S., Markesbery, W. R., & Lovell, M. A. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.08.016 · Cited by 90 · see citing works

Saffron as an antidote or a protective agent against natural or chemical toxicities

Razavi, B. M., & Hosseinzadeh, H. (2015) · DARU Journal of Pharmaceutical Sciences · doi:10.1186/s40199-015-0112-y · Cited by 89 · see citing works

Blood markers of oxidative stress in A lzheimer's disease

Skoumalová, A., & Hort, J. (2012) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2012.01585.x · Cited by 87 · see citing works

Effects of Local Curcumin on Oxidative Stress and Total Antioxidant Capacity in vivo Study

Al-Rubaei, Z. M. M., Mohammad, T. U., & Ali, L. K. (2014) · Pakistan Journal of Biological Sciences · doi:10.3923/pjbs.2014.1237.1241 · Cited by 80 · see citing works

Brain tocopherols related to Alzheimer's disease neuropathology in humans

Morris, M. C., Schneider, J. A., Li, H., Tangney, C., Nag, S., Bennett, D. A., Honer, W. G., & Barnes, L. L. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2013.12.015 · Cited by 79 · see citing works

Plasmalogens Inhibit APP Processing by Directly Affectingγ-Secretase Activity in Alzheimer’s Disease

Rothhaar, T. L., Grösgen, S., Haupenthal, V. J., Burg, V. K., Hundsdörfer, B., Mett, J., Riemenschneider, M. J., Grimm, H. S., Hartmann, T., & Grimm, M. O. W. (2012) · The Scientific World JOURNAL · doi:10.1100/2012/141240 · Cited by 74 · see citing works

Deferiprone Reduces Amyloid-β and Tau Phosphorylation Levels but not Reactive Oxygen Species Generation in Hippocampus of Rabbits Fed a Cholesterol-Enriched Diet

Prasanthi, J. R. P., Schrag, M., Dasari, B., Marwarha, G., Dickson, A., Kirsch, W. M., & Ghribi, O. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-111346 · Cited by 68 · see citing works

APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer’s disease

Abdul, H. M., Wenk, G. L., Gramling, M., Hauss‐Wegrzyniak, B., & Butterfield, D. A. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.06.077 · Cited by 68 · see citing works

Reduced amyloid‐β degradation in early A lzheimer's disease but not in the APP swe PS 1dE9 and 3x T g‐ AD mouse models

Stargardt, A., Gillis, J., Kamphuis, W., Wiemhoefer, A., Kooijman, L., Raspe, M. A., Benckhuijsen, W. E., Drijfhout, J. W., Hol, E. M., & Reits, E. A. (2013) · Aging Cell · doi:10.1111/acel.12074 · Cited by 66 · see citing works

Optimized Turmeric Extracts have Potent Anti-Amyloidogenic Effects

Shytle, R. D., Bickford, P. C., Rezai-Zadeh, K. P., Hou, L., Zeng, J., Tan, J., Sanberg, P. R., Sanberg, C. D., Roschek, B., Fink, R. C., et al. (2009) · Current Alzheimer Research · doi:10.2174/156720509790147115 · Cited by 59 · see citing works

Risk of Mortality with Vitamin E Supplements: The Cache County Study

Hayden, K. M., Welsh-Bohmer, K. A., Wengreen, H. J., Zandi, P. P., Lyketsos, C. G., & Breitner, J. C. S. (2007) · The American Journal of Medicine · doi:10.1016/j.amjmed.2006.03.039 · Cited by 58 · see citing works

Lipid Oxidation and Cardiovascular Disease: Introduction to a Review Series

McIntyre, T. M., & Hazen, S. L. (2010) · Circulation Research · doi:10.1161/circresaha.110.224618 · Cited by 58 · see citing works

Antioxidant Pathways in Alzheimers Disease: Possibilities of Intervention

Viña, J., Lloret, A., Giraldo, E., Badía, M., & Alonso, M. D. R. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211798357755 · Cited by 58 · see citing works

Effect of Vitamin E Administration on the Elevated Oxygen Stress and the Telomeric and Subtelomeric Status in Alzheimer’s Disease

Guan, J.-Z., Guan, W.-P., Maeda, T., & Makino, N. (2011) · Gerontology · doi:10.1159/000327821 · Cited by 57 · see citing works

The link between cholesterol and Alzheimer's disease

Sjögren, M., & Blennow, K. (2005) · World Journal of Biological Psychiatry · doi:10.1080/15622970510029795 · Cited by 57 · see citing works

Pro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial.

Winterbone, M. S., Sampson, M., Saha, S., Hughes, J. C., & Hughes, D. A. (2007) · Cardiovascular Diabetology · doi:10.1186/1475-2840-6-8 · Cited by 55 · see citing works

PROTECTIVE EFFECTS OF ANTIOXIDANT SUPPLEMENTATION ON PLASMA LIPID PEROXIDATION IN SMOKERS

Kim, H. S., & Lee, B. M. (2001) · Journal of Toxicology and Environmental Health · doi:10.1080/152873901316857761 · Cited by 54 · see citing works

Saffron ethanolic extract attenuates oxidative stress, spatial learning, and memory impairments induced by local injection of ethidium bromide.

Ghaffari, S. M., Hatami, H., & Dehghan, G. (2015) · PubMed Central · Cited by 46 · see citing works

Vitamin E Use Is Associated with Improved Survival in an Alzheimer’s Disease Cohort

Pavlik, V., Doody, R. S., Rountree, S. D., & Darby, E. J. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000255105 · Cited by 45 · see citing works

A turning point for Alzheimer's disease?

de la Torre, J. C. (2012) · BioFactors · doi:10.1002/biof.200 · Cited by 44 · see citing works

The conflicting role of brain cholesterol in Alzheimer's disease: lessons from the brain plasminogen system.

Ledesma, M. D., & Dotti, C. G. (2005) · Biochemical Society Symposia · doi:10.1042/bss0720129 · Cited by 41 · see citing works

Effects of vitamin E supplementation on exercise-induced oxidative stress: a meta-analysis

Stepanyan, V., Crowe, M., Haleagrahara, N., & Bowden, B. F. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0566 · Cited by 41 · see citing works

Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus

Hansen, S. L., Nielsen, A. H., Knudsen, K. E., Artmann, A., Petersen, G. L., Kristiansen, U., Hansen, S. H., & Hansen, H. S. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.10.012 · Cited by 39 · see citing works

Modulatory effects of vitamin E, acetyl-l-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model

Ahmed, H. H. (2010) · Experimental and Toxicologic Pathology · doi:10.1016/j.etp.2010.11.012 · Cited by 37 · see citing works

Vitamin E Inhibits Oxidative Stress-Induced Denaturation of Nerve Terminal Proteins Involved in Neurotransmission

Kaneai, N., Arai, M., Takatsu, H., Fukui, K., & Urano, S. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2011-111133 · Cited by 34 · see citing works

Vitamin E: Curse or benefit in Alzheimer's disease? A systematic investigation of the impact of α-, γ- and δ-tocopherol on Aβ generation and degradation in neuroblastoma cells

Grimm, M. O. W., Stahlmann, C. P., Mett, J., Haupenthal, V. J., Zimmer, V. C., Lehmann, J., Hundsdörfer, B., Endres, K., Grimm, H. S., & Hartmann, T. (2015) · The journal of nutrition health & aging · doi:10.1007/s12603-015-0506-z · Cited by 29 · see citing works

Insulin to treat Alzheimer’s disease: just follow your nose?

Schiöth, H. B., Frey, W. H., Brooks, S. J., & Benedict, C. (2011) · Expert Review of Clinical Pharmacology · doi:10.1586/ecp.11.70 · Cited by 27 · see citing works

Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer’s disease: a stochastic modelling approach

Proctor, C. J., Pienaar, I. S., Elson, J. L., & Kirkwood, T. B. L. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-32 · Cited by 26 · see citing works

Prooxidant Activity of Oxidized α‐Tocopherol in Vegetable Oils

Chapman, T. M., Kim, H. J., & MIN, D. B. S. (2009) · Journal of Food Science · doi:10.1111/j.1750-3841.2009.01262.x · Cited by 24 · see citing works

The two faces of α- and γ-tocopherols: an in vitro and ex vivo investigation into VLDL, LDL and HDL oxidation

Nadeem, N., Woodside, J. V., Kelly, S. M., Allister, R., Young, I. S., & McEneny, J. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2011.04.009 · Cited by 23 · see citing works

Vitamin E slows the progression of hypercholesterolemia-induced oxidative stress in heart, liver and kidney

Prasad, K., McNair, E. D., Qureshi, A. M., & Caspar‐Bell, G. (2012) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-012-1358-z · Cited by 22 · see citing works

Therapeutic Effects of Curcumin on Alzheimer’s Disease

Yao, E. C., & Xue, L. (2014) · Advances in Alzheimer s Disease · doi:10.4236/aad.2014.34014 · Cited by 19 · see citing works

Combination Therapy of Acetylcholinesterase Inhibitor and Vitamin E in Alzheimer Disease

Bittner, D. (2009) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e3181b54961 · Cited by 9 · see citing works

Lipid peroxidation and Alzheimer’s disease: Key role of Amyloid-β

Kontush, A. (2006) · Oléagineux Corps gras Lipides · doi:10.1051/ocl.2006.2222 · Cited by 8 · see citing works

Drugs for alzheimer’s disease

Cranwell-Bruce, L. A. (1990) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.28.11.42 · Cited by 8 · see citing works

Protection against cephalosporin-induced lipid peroxidation and nephrotoxicity by (+)-cyanidanol-3 and vitamin E

Cojocel, C., Tolle, K.-L., El-Hajj, H., et al. (2007) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2007000600017 · Cited by 5 · see citing works

An Ultrastructural Study of the Antioxidant Effects of Vitamin E and Fennel Extract on Zona Pellucida Cell Changes of Rat Ovaries under Non-Ionizing 50Hz Electromagnetic Fields

Asghari, A., Montaseri, A., & Khaki, A. A. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2 · see citing works

Phytotherapy: A promising approach for the treatment of Alzheimer's disease

John, O. O., Amarachi, I. S., Chinazom, A. P., Adaeze, E., Kale, M. B., Umare, M. D., & Upaganlawar, A. B. (2022) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2021.100030 · Cited by 69 · see citing works

The Multifaceted Role of Neuroprotective Plants in Alzheimer’s Disease Treatment

Zieneldien, T., Kim, J., & Cao, C. (2022) · Geriatrics · doi:10.3390/geriatrics7020024 · Cited by 29 · see citing works

Whole-plant foods and their macromolecules: untapped approaches to modulate neuroinflammation in Alzheimer’s disease

Huang, R., Zhu, Z., Wu, Q., Bekhit, A. E.-D. A., Wu, S., Chen, M., Wang, J., & Ding, Y. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1975093 · Cited by 23 · see citing works

Metabolic Fate of Curcumin in the Gastrointestinal Tract in Mice

Li, Z., Sun, Y., Song, M., et al. (2016) · The FASEB Journal · doi:10.1096/fasebj.30.1_supplement.690.9 · Cited by 1 · see citing works

Anti Oxidant Potential of “Cureit”- A Novel BioAvailable Curcumin Formulation

Gopia, S., Georgea, R., & .Sriraamb, V. T. (2014) · Asian Journal of Pharmaceutical Technology and Innovation · Cited by 5 · see citing works

Evaluation of Curcumin Nanoparticles against Rabbit Skin Infection

Fatthi, D. A. (2023) · E3S Web of Conferences · doi:10.1051/e3sconf/202339101119

Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment

Bondı̀, M. L., Emma, M. R., Botto, C., Augello, G., Azzolina, A., Gaudio, F. D., Craparo, E. F., Cavallaro, G., Bachvarov, D. R., & Cervello, M. (2017) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6b04409 · Cited by 65 · see citing works

Analysis of the anticancer activity of curcuminoids, thiotryptophan and 4-phenoxyphenol derivatives

Parsai, S., Keck, R. W., Skrzypczak‐Jankun, E., & Jankun, J. (2013) · Oncology Letters · doi:10.3892/ol.2013.1679 · Cited by 24 · see citing works