The Efficacy of Web-Based Cognitive Behavioral Interventions for Chronic Pain: A Systematic Review and Meta-Analysis
Open accessAbstract
Unlabelled Our objective was to conduct a systematic review and meta-analysis to quantify the efficacy of web-based cognitive behavioral interventions for the treatment of patients with chronic pain. MEDLINE and other databases were searched as data sources. Reference lists were examined for other relevant articles. We included 11 studies that evaluated the effects of web-based interventions on chronic pain using specific scales of pain. The pooled effect size (standardized mean difference between intervention versus waiting-list group means) from a random effects model was .285 (95% confidence interval: .145-.424), favoring the web-based intervention compared with the waiting-list group, although the effect was small. In addition, these results were not driven by any particular study, as shown by sensitivity analysis. Results from funnel plot argue against publication bias. Finally, the average dropout rate was 26.6%. In our meta-analysis, we demonstrate a small effect of web-based interventions, when using pain scale as the main outcome. Despite the minor effects and high dropout rates, the decreased costs and minor risk of adverse effects compared with pharmacological treatments support additional studies in chronic pain patients using web-based interventions. Further studies will be important to confirm the effects and determine the best responders to this intervention.Perspective Our findings suggest that web-based interventions for chronic pain result in small pain reductions in the intervention group compared with waiting-list control groups. These results advance the field of web-based cognitive behavioral interventions as a potential therapeutic tool for chronic pain and can potentially help clinicians and patients with chronic pain by decreasing treatment costs and side effects.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Internet-delivered psychological interventions have the potential to overcome environmental and economic barriers to the provision of evidence-based psychological treatment in the Irish health service context.
“Internet-delivered psychological interventions among people with chronic pain have the potential to overcome environmental and economic barriers to the provision of evidence-based psychological treatment in the Irish health service context.”
From Comparing the clinical-effectiveness and cost-effectiveness of an internet-delivered Acceptance and Commitment Therapy (ACT) intervention with a waiting list control among adults with chronic pain: study protocol for a randomised controlled trial (2014) · cites this paper as [30]
The Discussion says internet delivery can expand access for chronic-pain patients whose location prevents them from receiving care. The paper also describes the high cost of conventional CBT and the potential for lower-cost web-based treatment, while noting that cost-effectiveness remains uncertain. It does not assess these barriers in the Irish health service context. (LLM, conf=0.86)
Experimental — accuracy not yet measuredBehavioral modification techniques, such as cognitive behavioral therapy, do not necessarily require the therapist to be physically present with the patient.
“Behavioral modification techniques (BMTs), such as cognitive behavioral therapy, do not necessarily require the therapist to be physically present with the patient [12].”
From Behavior Modification Techniques on Patients with Chronic Pain in the Context of COVID-19 Telerehabilitation: An Umbrella Review (2022) · cites this paper as [12]
Internet-delivered psychological therapy aims to increase access to psychological intervention.
“One approach that aims to increase access to psychological intervention which has received increased attention in recent years is internet-delivered psychological therapy.22 24 26–30”
Internet-based interventions using cognitive behavioral approaches can be effective in promoting self-management of chronic pain conditions.
“Internet-based interventions using cognitive behavioral approaches can be effective in promoting self-management of chronic pain conditions [14-16].”
Previous systematic reviews on Web-based interventions for pain concluded that results were promising in terms of pain reduction and improvement of functional and emotional well-being.
“Overall, their authors concluded that results were promising in terms of pain reduction, and improvement of functional and emotional well-being.”
From Tailored web-based interventions for pain: Systematic review and meta-analysis (2017) · cites this paper as [15]
Other systematic reviews and meta-analyses on Web-based CBT, as well as traditional CBT, also reported small effects in the reduction of pain posttreatment compared with standard care or waiting list.
“Other systematic reviews and meta-analyses on Web-based CBT [15,18,19], as well as traditional CBT [65], also reported small effects in the reduction of pain posttreatment compared with standard care or waiting list.”
From Tailored web-based interventions for pain: Systematic review and meta-analysis (2017) · cites this paper as [15]
The withdrawal rate is similar to those reported in many iCBT, where an average dropout rate of 27% has been reported.
“The withdrawal rate is similar to those reported in many iCBT, where an average dropout rate of 27% has been reported [40].”
A sample size of 70 participants per group was needed to detect a moderate effect size in the primary outcome variable with a 2-sided 5% significance level and 80% power.
“A sample size of 70 participants per group was needed to detect a moderate effect size in the primary outcome variable with a 2-sided 5% significance level and 80% power.”
Reviews of Internet-based interventions for patients with various chronic pain conditions indicate a positive effect on pain, but results on psychological outcomes have been inconsistent.
“Reviews of Internet-based interventions for patients with various chronic pain conditions indicate a positive effect on pain, but results on psychological outcomes have been inconsistent [14,15,62].”
Many studies involved treatment programs delivered via the internet or through smartphone apps, with the aim of self-management by patients (no intervention by the therapist).
“Moreover, many studies involved treatment programs delivered via the internet or through smartphone apps, with the aim of self-management by patients (no intervention by the therapist) [21-23].”
Online cognitive-behavioral therapy for chronic pain results in small improvements in pain, disability, depression, and anxiety at post-treatment, with improvements in disability maintained at follow-up.
“Regarding chronic pain management, systematic reviews and meta-analyses have reported, similar to the findings of reviews of traditional face-to-face therapies, that online CBT for chronic pain results in small improvements in pain, disability, depression, and anxiety at post-treatment, with improvements in disability maintained at follow-up assessments.3,12,29”
From Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Fibromyalgia (2018) · cites this paper as [29]
Adapting empirically supported treatments into online delivery platforms makes them more accessible, particularly to those living in remote areas, with outcomes often rivaling those for in-clinic treatment.
“However, one increasingly used approach to overcoming these obstacles has been to adapt empirically supported treatments into online delivery platforms that make them more accessible, particularly to those living in remote areas,29,43,47 with outcomes often rivaling those for in-clinic treatment.10,14”
From Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Fibromyalgia (2018) · cites this paper as [29]
This study adds to a growing list of ACT RCTs for chronic pain and to the body of literature supporting the ongoing development and evaluation of online cognitive and behavioral treatments for chronic pain.
“Thus, this study adds to a growing list of ACT RCTs for chronic pain,18,23 and the body of literature supporting the ongoing development and evaluation of online cognitive and behavioral treatments for chronic pain.3,12,29”
From Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Fibromyalgia (2018) · cites this paper as [29]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Eccleston, C., & Morley, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub3 · Cited by 1,634 · see citing works
Morley, S., Eccleston, C., & Williams, A. (1999) · Pain · doi:10.1016/s0304-3959(98)00255-3 · Cited by 1,597 · see citing works
Treating anxiety disorders in children: Results of a randomized clinical trial.
Kendall, P. C. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.62.1.100 · Cited by 1,376 · see citing works
Wantland, D. J., Portillo, C. J., Holzemer, W. L., Slaughter, R., & McGhee, E. M. (2004) · Journal of Medical Internet Research · doi:10.2196/jmir.6.4.e40 · Cited by 966 · see citing works
Sirey, J. A., Bruce, M. L., Alexopoulos, G. S., Perlick, D. A., Friedman, S. J., & Meyers, B. S. (2001) · Psychiatric Services · doi:10.1176/appi.ps.52.12.1615 · Cited by 796 · see citing works
Griffiths, K. M., Christensen, H., Jorm, A. F., Evans, K., & Groves, C. (2004) · British Journal of Psychiatry · doi:10.1192/bjp.185.4.342 · Cited by 789 · see citing works
Chronic pain and depression: Does the evidence support a relationship?
Romano, J. M., & Turner, J. A. (1985) · Psychological Bulletin · doi:10.1037/0033-2909.97.1.18 · Cited by 732 · see citing works
Enduring Effects for Cognitive Behavior Therapy in the Treatment of Depression and Anxiety
Hollon, S. D., Stewart, M. O., & Strunk, D. (2006) · Annual Review of Psychology · doi:10.1146/annurev.psych.57.102904.190044 · Cited by 466 · see citing works
Internet-Based Chronic Disease Self-Management: A Randomized Trial
Lorig, K. R., Ritter, P. L., Laurent, D. D., & Plant, K. (2006) · Medical Care · doi:10.1097/01.mlr.0000233678.80203.c1 · Cited by 450 · see citing works
Lorig, K. R., Ritter, P. L., Laurent, D. D., & Plant, K. (2008) · Arthritis Care & Research · doi:10.1002/art.23817 · Cited by 440 · see citing works
Population based intervention to change back pain beliefs and disability: three part evaluation
Buchbinder, R., Jolley, D., & Wyatt, M. (2001) · BMJ · doi:10.1136/bmj.322.7301.1516 · Cited by 426 · see citing works
Long-term follow-up of a cognitive-behavioral therapy for anxiety-disordered youth.
Kendall, P. C., & Southam‐Gerow, M. A. (1996) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.64.4.724 · Cited by 345 · see citing works
Hollon, S. D., Muñoz, R. F., Barlow, D. H., Beardslee, W. R., Bell, C. C., Bernal, G., Clarke, G. N., Franciosi, L. P., Kazdin, A. E., Kohn, L. P., et al. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01384-7 · Cited by 327 · see citing works
Wright, J. H., Wright, A. S., Albano, A. M., Basco, M. R., Goldsmith, L. J., Raffield, T., & Otto, M. W. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.6.1158 · Cited by 319 · see citing works
Is internet-based CBT for panic disorder and agoraphobia as effective as face-to-face CBT?
Kiropoulos, L. A., Klein, B., Austin, D. W., Gilson, K., Pier, C., Mitchell, J., & Ciechomski, L. (2008) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2008.01.008 · Cited by 290 · see citing works
A controlled trial of self-help treatment of recurrent headache conducted via the Internet.
Ström, L., Pettersson, R., & Andersson, G. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.4.722 · Cited by 267 · see citing works
Long-term follow-up of a cognitive–behavioral therapy for anxiety-disordered youth.
Kendall, P. C., & Southam‐Gerow, M. A. (1996) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.64.4.724 · Cited by 263 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Eccleston, C., Williams, A. C. D. C., & Morley, S. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub2 · Cited by 247 · see citing works
Some implications of learning in problems of chronic pain
Fordyce, W. E., Fowler, R. S., Lehmann, J. F., & Delateur, B. J. (1968) · Journal of Chronic Diseases · doi:10.1016/0021-9681(68)90015-5 · Cited by 239 · see citing works
Controlled trial of Internet-based treatment with telephone support for chronic back pain
Buhrman, M., Fältenhag, S., Ström, L., & Andersson, G. (2004) · Pain · doi:10.1016/j.pain.2004.07.021 · Cited by 232 · see citing works
Online psychological treatment for pediatric recurrent pain: A randomized evaluation
Hicks, C. L., von Baeyer, C. L., & McGrath, P. J. (2006) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsj065 · Cited by 217 · see citing works
Lorig, K. R., Laurent, D. D., Deyo, R. A., Marnell, M. E., Minor, M. A., & Ritter, P. L. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.7.792 · Cited by 206 · see citing works
A randomized controlled trial of an internet-based treatment for chronic headache
Devineni, T., & Blanchard, E. B. (2005) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.01.008 · Cited by 203 · see citing works
Barriers to initiating depression treatment in primary care practice
Nutting, P. A., ROST, K. M., Dickinson, M., Werner, J. J., Dickinson, W. P., Smith, J. L., & Gallovic, B. (2002) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2002.10128.x · Cited by 191 · see citing works
Psychotherapy mediated by remote communication technologies: a meta-analytic review
Bee, P. E., Bower, P., Lovell, K., Gilbody, S., Richards, D., Gask, L., & Roach, P. (2008) · BMC Psychiatry · doi:10.1186/1471-244x-8-60 · Cited by 189 · see citing works
Lorig, K. R., Ritter, P. L., Dost, A., Plant, K., Laurent, D. D., & Mcneil, I. (2008) · Chronic Illness · doi:10.1177/1742395308098886 · Cited by 182 · see citing works
Mackinnon, A. J., Griffiths, K. M., & Christensen, H. M. (2008) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.106.032078 · Cited by 182 · see citing works
Gega, L., Marks, I., & Mataix‐Cols, D. (2004) · Journal of Clinical Psychology · doi:10.1002/jclp.10241 · Cited by 150 · see citing works
The Effectiveness of an Online Mind-Body Intervention for Older Adults With Chronic Pain
Berman, R. L. H., Iris, M. A., Bode, R. K., & Drengenberg, C. (2008) · Journal of Pain · doi:10.1016/j.jpain.2008.07.006 · Cited by 140 · see citing works
Internet‐Based Treatment of Headache: Does Telephone Contact Add Anything?
Andersson, G., Lundström, P., & Ström, L. (2003) · Headache: The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2003.03070.x · Cited by 136 · see citing works
Headstrong: A Pilot Study of a CD-ROM Intervention for Recurrent Pediatric Headache
Connelly, M. A., Rapoff, M. A., Thompson, N., & Connelly, W. (2005) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsj003 · Cited by 103 · see citing works
New Insights Into Neuromodulatory Approaches for the Treatment of Pain
Jensen, M. P., Hakimian, S., Sherlin, L. H., & Fregni, F. (2007) · Journal of Pain · doi:10.1016/j.jpain.2007.11.003 · Cited by 97 · see citing works
Self-citationInternet-based rehabilitation for individuals with chronic pain and burnout: a randomized trial
Brattberg, G. (2006) · International Journal of Rehabilitation Research · doi:10.1097/01.mrr.0000210055.17291.f5 · Cited by 69 · see citing works
Loh, P., Flicker, L. A., & Horner, B. (2009) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2009.02.012 · Cited by 52 · see citing works
Schulz, P. J., Rubinell, S., & Hartung, U. (2007) · International Journal of Public Health · doi:10.1007/s00038-007-5127-9 · Cited by 43 · see citing works
Warmerdam, L., van Straten, A., & Cuijpers, P. J. (2007) · BMC Psychiatry · doi:10.1186/1471-244x-7-72 · Cited by 30 · see citing works
Brattberg, G. (2007) · International Journal of Rehabilitation Research · doi:10.1097/mrr.0b013e32829fa545 · Cited by 29 · see citing works
Hubbard, P. A., Broome, M. E., & Antia, L. A. (2005) · PubMed · Cited by 26 · see citing works
Applying World Wide Web Technology to the Study of Patients with Rare Diseases
de Groen, P. C., Barry, J. A., & Schaller, W. J. (1998) · Annals of Internal Medicine · doi:10.7326/0003-4819-129-2-199807150-00009 · Cited by 21 · see citing works
Web-based Training for Implementing Evidence-Based Management of Postpartum Depression
Baker, C. D., Kamke, H. E., O'Hara, M. W., & Stuart, S. P. (2009) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2009.05.080265 · Cited by 18 · see citing works
Chronic pain: clinical features, assessment and treatment
Mackintosh, C., & Elson, S. (2008) · Nursing Standard · doi:10.7748/ns2008.10.23.5.48.c6680 · Cited by 13 · see citing works
Chronic pain: clinical features, assessment and treatment
Mackintosh, C., & Elson, S. (2008) · Nursing Standard · doi:10.7748/ns.23.5.48.s54 · Cited by 6 · see citing works
The new telecare: emerging Internet-based models for home healthcare.
Harris, G. (1999) · PubMed · Cited by 4 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- American Academy of Orthopaedic Surgeons: Musculo- skeletal conditions in the United States. Available at: http://www2.aaos.org/aaos/archives/bulletin/oct99/musculo. htm. Accessed July 10, 2009
- Cognitive Therapy of Depression, Beck AT, Rush AJ, Shaw BJ, Emery G (eds), 1st ed. New York, NY, Guilford Press, 1979
- National Headache Foundation: Migraine prevention summit proceedings. Available at http://www.headaches. org/pdf/Monograph12.pdf Accessed September 2, 2009
- National Institute of Neurological Disorders and Stroke: Second Annual Research Symposium for Advances in Pain Research. Available at http://www.ninds.nih.gov/news_and_ events/proceedings/Advances_Pain_Research_Second_Annual. htm. Accessed September 21, 2009
Cited by
Sorted by citations
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Eccleston, C., & Morley, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub3 · Cited by 1,634 · see citing works
Ehde, D. M., Dillworth, T. M., & Turner, J. A. (2014) · American Psychologist · doi:10.1037/a0035747 · Cited by 879 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Fisher, E., Hearn, L., & Eccleston, C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub4 · Cited by 605 · see citing works
Ebert, D. D., Van Daele, T., Nordgreen, T., Karekla, M., Compare, A., Zarbo, C., Brugnera, A., Øverland, S., Trebbi, G., Jensen, K. L., et al. (2018) · European Psychologist · doi:10.1027/1016-9040/a000318 · Cited by 437 · see citing works
Depression and chronic pain in the elderly: links and management challenges
Zis, P., Daskalaki, A., Bountouni, I., Sykioti, P., Varrassi, G., & Paladini, A. (2017) · Clinical Interventions in Aging · doi:10.2147/cia.s113576 · Cited by 458 · see citing works
Current and Future Trends in Internet-Supported Mental Health Interventions
Barak, A., & Grohol, J. M. (2011) · Journal of Technology in Human Services · doi:10.1080/15228835.2011.616939 · Cited by 373 · see citing works
Clinical Practice Guidelines for Pain Management in Acute Musculoskeletal Injury
Hsu, J. R., Mir, H. R., Wally, M. K., & Seymour, R. B. (2019) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0000000000001430 · Cited by 292 · see citing works
Buhrman, M., Skoglund, A., Husell, J., Bergström, K., Gordh, T., Hursti, T., Bendelin, N., Furmark, T., & Andersson, G. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2013.02.010 · Cited by 281 · see citing works
Kuester, A., Niemeyer, H., & Knaevelsrud, C. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.11.004 · Cited by 261 · see citing works
Psychological therapies (Internet-delivered) for the management of chronic pain in adults
Eccleston, C., Fisher, E., Craig, L., Duggan, G. B., Rosser, B. A., & Keogh, E. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010152.pub2 · Cited by 271 · see citing works
Psychological therapies for the management of chronic pain
Sturgeon, J. (2014) · Psychology Research and Behavior Management · doi:10.2147/prbm.s44762 · Cited by 259 · see citing works
Trompetter, H. R., Bohlmeijer, E. T., Veehof, M. M., & Schreurs, K. M. G. (2015) · Journal of Behavioral Medicine · doi:10.1007/s10865-014-9579-0 · Cited by 255 · see citing works
Fisher, E., Law, E. F., Palermo, T. M., & Eccleston, C. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011118.pub2 · Cited by 244 · see citing works
Internet interventions for chronic pain including headache: a systematic review
Buhrman, M., Gordh, T., & Andersson, G. (2016) · Internet Interventions · doi:10.1016/j.invent.2015.12.001 · Cited by 223 · see citing works
Establishing Guidelines for Executing and Reporting Internet Intervention Research
Proudfoot, J., Klein, B., Barak, A., Carlbring, P., Cuijpers, P., Lange, A., Ritterband, L., & Andersson, G. (2011) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2011.573807 · Cited by 202 · see citing works
Jensen, M. P., & Turk, D. C. (2014) · American Psychologist · doi:10.1037/a0035641 · Cited by 196 · see citing works
Chronic Pain and Cognitive Behavioral Therapy: An Integrative Review
Knoerl, R., Lavoie Smith, E. M., & Weisberg, J. (2016) · Western Journal of Nursing Research · doi:10.1177/0193945915615869 · Cited by 194 · see citing works
van Beugen, S., Ferwerda, M., Hoeve, D., Rovers, M. M., Spillekom-van Koulil, S., van Middendorp, H., & Evers, A. W. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.2777 · Cited by 189 · see citing works
Dear (2015) · doi:10.1097/j.pain.0000000000000251 · Cited by 187 · see citing works
Müller, R., Gertz, K. J., Molton, I. R., Terrill, A. L., Bombardier, C. H., Ehde, D. M., & Jensen, M. P. (2016) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000225 · Cited by 179 · see citing works
Kristjánsdóttir, Ó. B., Fors, E. A., Eide, E., Finset, A., Stensrud, T. L., van Dulmen, S., Wigers, S. H., & Eide, H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2249 · Cited by 176 · see citing works
Dear, B. F., Titov, N., Perry, K. N., Johnston, L., Wootton, B. M., Terides, M. D., Rapee, R. M., & Hudson, J. L. (2013) · Pain · doi:10.1016/j.pain.2013.03.005 · Cited by 182 · see citing works
A randomized controlled evaluation of an online chronic pain self management program
Ruehlman, L. S., Karoly, P., & Enders, C. (2012) · Pain · doi:10.1016/j.pain.2011.10.025 · Cited by 172 · see citing works
Fisher, E., Law, E., Dudeney, J., Eccleston, C., & Palermo, T. M. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011118.pub3 · Cited by 164 · see citing works
Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Fibromyalgia
Simister, H. D., Tkachuk, G. A., Shay, B. L., Vincent, N., Pear, J. J., & Skrabek, R. Q. (2018) · The Journal of Pain · doi:10.1016/j.jpain.2018.02.004 · Cited by 157 · see citing works
Automated Internet-based pain coping skills training to manage osteoarthritis pain
Rini, C. K., Porter, L. S., Somers, T. J., McKee, D. C., DeVellis, R. F., Smith, M. Y., Winkel, G. H., Ahern, D. K., Goldman, R. E., Stiller, J. L., et al. (2015) · Pain · doi:10.1097/j.pain.0000000000000121 · Cited by 150 · see citing works
Psychological factors and treatment opportunities in low back pain
Pincus, T., & McCracken, L. M. (2013) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2013.09.010 · Cited by 144 · see citing works
Stinson, J. N., Lalloo, C., Harris, L., Isaac, L., Campbell, F., Brown, S., Ruskin, D., Gordon, A., Galonski, M., Pink, L. R., et al. (2014) · Pain Research and Management · doi:10.1155/2014/935278 · Cited by 149 · see citing works
Baumeister, H., Seifferth, H., Lin, J., Nowoczin, L., Lüking, M., & Ebert, D. (2015) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000118 · Cited by 124 · see citing works
Karekla, M., Kasinopoulos, O., Neto, D. D., Ebert, D. D., Van Daele, T., Nordgreen, T., Höfer, S., Oeverland, S., & Jensen, K. L. (2019) · European Psychologist · doi:10.1027/1016-9040/a000349 · Cited by 117 · see citing works
Heapy, A. A., Higgins, D. M., Cervone, D., Wandner, L., Fenton, B. T., & Kerns, R. D. (2015) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000185 · Cited by 128 · see citing works
Boersma, K., Södermark, M., Hesser, H., Flink, I. K., Gerdle, B., & Linton, S. J. (2019) · Pain · doi:10.1097/j.pain.0000000000001575 · Cited by 123 · see citing works
Adamse, C., Dekker-Van Weering, M. G., van Etten-Jamaludin, F. S., & Stuiver, M. M. (2018) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x17716576 · Cited by 115 · see citing works
Dowd, H., Hogan, M. J., McGuire, B. E., Davis, M. C., Sarma, K. M., Fish, R. A., & Zautra, A. J. (2015) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000201 · Cited by 121 · see citing works
Krein, S. L., Kadri, R., Hughes, M. V., Kerr, E. A., Piette, J. D., Holleman, R. G., Kim, H. M., & Richardson, C. R. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2605 · Cited by 108 · see citing works
Moman, R. N., Dvorkin, J., Pollard, E. M., Wanderman, R., Murad, M. H., Warner, D. O., & Hooten, W. M. (2019) · Pain Medicine · doi:10.1093/pm/pnz164 · Cited by 93 · see citing works
Chen, T., Or, C. K., & Chen, J. (2020) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocaa282 · Cited by 98 · see citing works
Lin, J., Faust, B., Ebert, D. D., Krämer, L., & Baumeister, H. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9925 · Cited by 97 · see citing works
A quality review of smartphone applications for the management of pain
Portelli, P., & Eldred, C. (2016) · British Journal of Pain · doi:10.1177/2049463716638700 · Cited by 94 · see citing works
Friesen, L. N., Hadjistavropoulos, H. D., Schneider, L. H., Alberts, N. M., Titov, N., & Dear, B. F. (2017) · Pain · doi:10.1097/j.pain.0000000000000802 · Cited by 89 · see citing works
Patients’ Needs and Requirements for eHealth Pain Management Interventions: Qualitative Study
Ledel Solem, I. K., Varsi, C., Eide, H., Kristjansdottir, O. B., Mirkovic, J., Børøsund, E., Haaland-Øverby, M., Heldal, K., Schreurs, K. M., Waxenberg, L. B., et al. (2019) · Journal of Medical Internet Research · doi:10.2196/13205 · Cited by 80 · see citing works
Castelnuovo, G., Giusti, E. M., Manzoni, G. M., Saviola, D., Gatti, A., Gabrielli, S., Lacerenza, M., Pietrabissa, G., Cattivelli, R., Spatola, C. A. M., et al. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00115 · Cited by 91 · see citing works
Cranen, K., Groothuis‐Oudshoorn, C. G. M., Vollenbroek-Hutten, M. M. R., & IJzerman, M. J. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.5951 · Cited by 91 · see citing works
Tailored web-based interventions for pain: Systematic review and meta-analysis
Martorella, G., Boitor, M., Berube, M., Fredericks, S., Le May, S., & Gélinas, C. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.8826 · Cited by 88 · see citing works
Side effects in internet-based interventions for social anxiety disorder
Boettcher, J., Rozental, A., Andersson, G., & Carlbring, P. (2014) · Internet Interventions · doi:10.1016/j.invent.2014.02.002 · Cited by 88 · see citing works
Empowering Patients with Persistent Pain Using an Internet-based Self-Management Program
Wilson, M., Roll, J. M., Corbett, C., & Barbosa-Leiker, C. (2015) · Pain Management Nursing · doi:10.1016/j.pmn.2014.09.009 · Cited by 83 · see citing works
Kristjánsdóttir, Ó. B., Fors, E. A., Eide, E., Finset, A., van Dulmen, S., Wigers, S. H., & Eide, H. (2011) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-12-51 · Cited by 86 · see citing works
Stinson, J., White, M., Isaac, L., Campbell, F., Brown, S., Ruskin, D., Gordon, A., Galonski, M., Pink, L., Buckley, N., et al. (2013) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31826dce65 · Cited by 81 · see citing works
Vugts, M. A. P., Joosen, M. C. W., van der Geer, J. E., Zedlitz, A. M. E. E., & Vrijhoef, H. J. M. (2018) · PLOS ONE · doi:10.1371/journal.pone.0196467 · Cited by 85 · see citing works
Buhrman, M., Syk, M., Burvall, O., Hartig, T., Gordh, T., & Andersson, G. (2015) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000176 · Cited by 83 · see citing works
Wetherell, J. L., Petkus, A. J., Alonso‐Fernandez, M., Bower, E. S., Steiner, A. R. W., & Afari, N. (2016) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4330 · Cited by 78 · see citing works
Lin, J., Klatt, L.-I., McCracken, L. M., & Baumeister, H. (2018) · PAIN · doi:10.1097/j.pain.0000000000001134 · Cited by 76 · see citing works
Kristjánsdóttir, Ó. B., Fors, E. A., Eide, E., Finset, A., Stensrud, T. L., van Dulmen, S., Wigers, S. H., & Eide, H. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2442 · Cited by 78 · see citing works
Rini, C. K., Williams, D. A., Broderick, J. E., & Keefe, F. J. (2012) · Translational Behavioral Medicine · doi:10.1007/s13142-011-0107-2 · Cited by 76 · see citing works
Alonso-Fernández, M., López-López, A., Losada, A., González, J. L., & Wetherell, J. L. (2016) · Pain Medicine · doi:10.1111/pme.12885 · Cited by 73 · see citing works
Leading the Way to Solutions to the Opioid Epidemic: AOA Critical Issues
Seymour, R. B., Ring, D., Higgins, T., & Hsu, J. R. (2017) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.17.00066 · Cited by 74 · see citing works
Hypnosis and the Alleviation of Clinical Pain: A Comprehensive Meta-Analysis
Milling, L. S., Valentine, K. E., LoStimolo, L. M., Nett, A. M., & McCarley, H. S. (2021) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2021.1920330 · Cited by 74 · see citing works
Becker, W. C., DeBar, L. L., Heapy, A. A., Higgins, D., Krein, S. L., Lisi, A., Makris, U. E., & Allen, K. D. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4345-6 · Cited by 59 · see citing works
Malliaras, P., Cridland, K., Hopmans, R., Ashton, S., Littlewood, C., Page, R. S., Harris, I. A., Skouteris, H., & Haines, T. P. (2020) · JMIR mhealth and uhealth · doi:10.2196/24311 · Cited by 64 · see citing works
A randomized controlled trial of an online self-management program for adults with arthritis pain
Trudeau, K. J., Pujol, L. A. M., DasMahapatra, P., Wall, R., Black, R. A., & Zacharoff, K. L. (2015) · Journal of Behavioral Medicine · doi:10.1007/s10865-015-9622-9 · Cited by 60 · see citing works
Buhrman, M., Fredriksson, A., Edström, G., Shafiei, D., Tärnqvist, C., Ljótsson, B., Hursti, T., Gordh, T., & Andersson, G. (2013) · European Journal of Pain · doi:10.1002/j.1532-2149.2012.00244.x · Cited by 60 · see citing works
Dear, B. F., Gandy, M., Karin, E., Ricciardi, T., Fogliati, V. J., McDonald, S., Staples, L. G., Perry, K. N., Sharpe, L., Nicholas, M. K., et al. (2017) · Pain · doi:10.1097/j.pain.0000000000000916 · Cited by 57 · see citing works
Knoerl, R., Smith, E., Barton, D. L., Williams, D. A., Holden, J. E., Krauss, J. C., & Lavasseur, B. I. (2017) · Journal of Pain · doi:10.1016/j.jpain.2017.11.009 · Cited by 59 · see citing works
Markozannes, G., Aretouli, E., Rintou, E., Dragioti, E., Damigos, D., Ntzani, E., Εvangelou, Ε., & Tsilidis, K. K. (2017) · BMC Psychology · doi:10.1186/s40359-017-0200-5 · Cited by 58 · see citing works
Nevedal, D. C., Wang, C., Oberleitner, L., Schwartz, S., & Williams, A. M. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2296 · Cited by 57 · see citing works
Orofacial Pain: A Guide for the Headache Physician
Shephard, M. K., MacGregor, E. A., & Zakrzewska, J. M. (2013) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12272 · Cited by 56 · see citing works
Self-Help for Medically Unexplained Symptoms: A Systematic Review and Meta-Analysis
van Gils, A., Schoevers, R. A., Bonvanie, I. J., Gelauff, J. M., Roest, A. M., & Rosmalen, J. G. M. (2016) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000325 · Cited by 55 · see citing works
Cheng, J. O. S., & Cheng, S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0223367 · Cited by 57 · see citing works
Trompetter, H. R., Bohlmeijer, E. T., Lamers, S. M. A., & Schreurs, K. M. G. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00353 · Cited by 51 · see citing works
“At present, however, studies are lacking that specify for whom web-based cognitive behavioral interventions can be more or less profitable (Macea et al., 2010; Bender et al., 2011).”
BackgroundLin, J., Lüking, M., Ebert, D. D., Buhrman, M., Andersson, G., & Baumeister, H. (2015) · Internet Interventions · doi:10.1016/j.invent.2014.11.005 · Cited by 51 · see citing works
Fordham, B., Sugavanam, T., Edwards, K., Hemming, K., Howick, J., Copsey, B. J., Lee, H., Kaidesoja, M., Kirtley, S., Hopewell, S., et al. (2021) · Health Technology Assessment · doi:10.3310/hta25090 · Cited by 59 · see citing works
de Boer, M. J., Versteegen, G. J., Vermeulen, K. M., Sanderman, R., & Struys, M. M. R. F. (2014) · European Journal of Pain · doi:10.1002/ejp.509 · Cited by 51 · see citing works
van de Graaf, D. L., Trompetter, H. R., Smeets, T., & Mols, F. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100465 · Cited by 49 · see citing works
Sinha, C., Cheng, A. L., & Kadaba, M. (2022) · JMIR Formative Research · doi:10.2196/37302 · Cited by 47 · see citing works
Guarino, H., Fong, C., Marsch, L. A., Acosta, M. C., Syckes, C., Moore, S. K., Cruciani, R. A., Portenoy, R. K., Turk, D. C., & Rosenblum, A. (2017) · Pain Medicine · doi:10.1093/pm/pnx334 · Cited by 47 · see citing works
New Developments in the Psychological Management of Chronic Pain
Morley, S., & Williams, A. C. D. C. (2015) · The Canadian Journal of Psychiatry · doi:10.1177/070674371506000403 · Cited by 46 · see citing works
Shearer, H. M., Carroll, L., Wong, J. J., Côté, P., Varatharajan, S., Southerst, D., Sutton, D. A., Randhawa, K. A., Yu, H., Mior, S. A., et al. (2015) · The Spine Journal · doi:10.1016/j.spinee.2015.08.011 · Cited by 45 · see citing works
Optimizing Cognitive Function in Persons With Chronic Pain
Baker, K. S., Georgiou‐Karistianis, N., Gibson, S. J., & Giummarra, M. J. (2016) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000423 · Cited by 44 · see citing works
Herbert, M. S., Dochat, C., Wooldridge, J. S., Materna, K., Blanco, B. H., Tynan, M., Lee, M. W., Gasperi, M., Camodeca, A., Harris, D., et al. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2021.103995 · Cited by 44 · see citing works
Wilson, M., Finlay, M., Orr, M., Barbosa-Leiker, C., Sherazi, N., Roberts, M. L. A., Layton, M., & Roll, J. M. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.04.019 · Cited by 46 · see citing works
Mediators and moderators of chronic pain outcomes in an online self-management program.
DasMahapatra, P., Chiauzzi, E., Pujol, L. M., Los, C., & Trudeau, K. J. (2015) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000125 · Cited by 40 · see citing works
Dear, B. F., Gandy, M., Karin, E., Ricciardi, T., Langman, N., Staples, L. G., Fogliati, V. J., Sharpe, L., McLellan, L. F., & Titov, N. (2016) · Pain · doi:10.1097/j.pain.0000000000000639 · Cited by 40 · see citing works
Tan, G., Teo, I., Srivastava, D., Smith, D., Smith, S. L., Williams, W., & Jensen, M. P. (2013) · Pain Medicine · doi:10.1111/pme.12131 · Cited by 39 · see citing works
Nordin, C. A., Michaelson, P., Gard, G., & Eriksson, M. K. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5634 · Cited by 38 · see citing works
Ethical concerns for telemental health therapy amidst governmental surveillance.
Lustgarten, S. D., & Colbow, A. J. (2017) · American Psychologist · doi:10.1037/a0040321 · Cited by 39 · see citing works
Internet/smartphone-based applications for the treatment of tinnitus: a systematic review
Nagaraj, M. K., & Prabhu, P. (2019) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-019-05743-8 · Cited by 40 · see citing works
Preventing Chronic Pain: A Human Systems Approach—Results from a Massive Open Online Course
Fricton, J., Anderson, K., Clavel, A. L., Fricton, R., Hathaway, K. M., Kang, W., Jaeger, B. A., Maixner, W. D., Pesut, D. J., Russell, J., et al. (2015) · Global Advances in Health and Medicine · doi:10.7453/gahmj.2015.048 · Cited by 39 · see citing works
Gustafson, D. H., Kornfield, R., Mares, M., Johnston, D. C., Cody, O. J., Yang, E. F., Gustafson, D. H., Hwang, J., Mahoney, J., Curtin, J. J., et al. (2021) · Journal of General Internal Medicine · doi:10.1007/s11606-021-06888-1 · Cited by 41 · see citing works
Alkabbany, I. M., Ali, A., Foreman, C., Tretter, T. R., Hindy, N. C., & Farag, A. A. (2023) · Sensors · doi:10.3390/s23031614 · Cited by 37 · see citing works
Skinner, M. A., Wilson, H., & Turk, D. C. (2012) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.26.2.93 · Cited by 37 · see citing works
Karekla, M., Savvides, S. N., & Gloster, A. (2020) · Annals of Behavioral Medicine · doi:10.1093/abm/kaaa013 · Cited by 36 · see citing works
MacPherson, M., Bakker, A. M., Anderson, K., & Holtzman, S. (2022) · Canadian Journal of Pain · doi:10.1080/24740527.2022.2030212 · Cited by 36 · see citing works
Moore, S. K., Guarino, H., Acosta, M. C., Aronson, I. D., Marsch, L. A., Rosenblum, A., Grabinski, M. J., & Turk, D. C. (2013) · Pain Medicine · doi:10.1111/pme.12200 · Cited by 35 · see citing works
Rini, C. K., Porter, L. S., Somers, T. J., McKee, D. C., & Keefe, F. J. (2014) · Journal of Medical Internet Research · doi:10.2196/jmir.3374 · Cited by 35 · see citing works
A review of web-based chronic disease self-management for older adults
Portz, J. D. (2017) · Gerontechnology · doi:10.4017/gt.2017.16.1.002.00 · Cited by 35 · see citing works
Chronic prostatitis: current treatment options
Pirola, G. M., Verdacchi, T., Rosadi, S., Annino, F., & Angelis, M. D. (2019) · Research and Reports in Urology · doi:10.2147/rru.s194679 · Cited by 40 · see citing works
Taguchi, K., Numata, N., Takanashi, R., Takemura, R., Yoshida, T., Kutsuzawa, K., Yoshimura, K., Nozaki-Taguchi, N., Ohtori, S., & Shimizu, E. (2021) · Journal of Medical Internet Research · doi:10.2196/30690 · Cited by 34 · see citing works
Management of chronic pain through pain management programmes
Wilson, I. R. (2017) · British Medical Bulletin · doi:10.1093/bmb/ldx032 · Cited by 36 · see citing works
Greenwell, K., Sereda, M., Coulson, N., Refaie, A. E., & Hoare, D. J. (2016) · International Journal of Audiology · doi:10.3109/14992027.2015.1137363 · Cited by 34 · see citing works
Bendelin, N., Björkdahl, P., Risell, M., Nelson, K. Z., Gerdle, B., Andersson, G., & Buhrman, M. (2020) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-020-03198-1 · Cited by 33 · see citing works
“duration of symptoms are at risk for dropping out of internet delivered treatments [35, 36].”
Background
- Authors
- Macea, D. D., Gajos, K., Daglia Calil, Y. A., & Fregni, F.
- Affiliations
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Corresponding author
- Fregni, Felipe
- Venue
- The Journal of Pain
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 11
- Issue
- 10
- Pages
- 917-929
- ISSN
- 1526-5900 (ISSN-L)
- OpenAlex
- W2004931081
- Cited by
- 289
- References
- 42
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 14 · 2023: 12 · 2022: 16 · 2021: 26 · 2020: 16 · 2019: 25 · 2018: 18 · 2017: 30 · 2016: 22 · 2015: 25 · 2014: 27 · 2013: 20 · 2012: 10
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- chronic pain, online intervention, cognitive behavioral therapy, digital health, analgesia, waitlist control, dropout rates, treatment efficacy, cost-effectiveness
- MeSH terms
- Adult, Chronic Disease, Female, Humans, Male, Middle Aged, Pain, Cognitive Behavioral Therapy, Internet, Pain Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
