Genetics of familial and sporadic Alzheimer s disease

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Goate, A., Chartier-Harlin, M.-C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., et al. (1991) · Nature · doi:10.1038/349704a0 · Cited by 4,659 · see citing works

Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

Oddo, S., Caccamo, A., Shepherd, J. D., Murphy, M. P., Golde, T. E., Kayed, R., Metherate, R., Mattson, M. P., Akbari, Y., & LaFerla, F. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00434-3 · Cited by 4,126 · see citing works

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326 · see citing works

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

the European Alzheimer's Disease Initiative Investigators, Lambert, J.-C., Heath, S., Even, G., Campion, D., Sleegers, K., Hiltunen, M., Combarros, O., Zelenika, D., Bullido, M. J., et al. (2009) · Nature Genetics · doi:10.1038/ng.439 · Cited by 2,234 · see citing works

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

Rogaev, E. I., Sherrington, R., Rogaeva, E. A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T., et al. (1995) · Nature · doi:10.1038/376775a0 · Cited by 2,052 · see citing works

Siglecs and their roles in the immune system

Crocker, P. R., Paulson, J. C., & Varki, A. P. (2007) · Nature reviews. Immunology · doi:10.1038/nri2056 · Cited by 2,032 · see citing works

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Initiative, T. A. D. N., Hollingworth, P., CHARGE consortium, EADI1 consortium, Harold, D., Sims, R., Gerrish, A., Lambert, J.-C., Carrasquillo, M. M., Abraham, R., et al. (2011) · Nature Genetics · doi:10.1038/ng.803 · Cited by 1,997 · see citing works

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

Tanzi, R. E., & Bertram, L. (2005) · Cell · doi:10.1016/j.cell.2005.02.008 · Cited by 1,849 · see citing works

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

Glenner, G. G., & Wong, C. W. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(84)91209-9 · Cited by 1,693 · see citing works

The Alzheimer's Disease Neuroimaging Initiative

Mueller, S. G., Weiner, M. W., Thal, L. J., Petersen, R. C., Jack, C., Jagust, W., Trojanowski, J. Q., Toga, A. W., & Beckett, L. (2005) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2005.09.008 · Cited by 1,525 · see citing works

Apolipoprotein E in Alzheimer’s disease and other neurological disorders

Verghese, P. B., Castellano, J. M., & Holtzman, D. M. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70325-2 · Cited by 857 · see citing works

The Genetics of Alzheimer Disease: Back to the Future

Bertram, L., Lill, C. M., & Tanzi, R. E. (2010) · Neuron · doi:10.1016/j.neuron.2010.10.013 · Cited by 834 · see citing works

The genetics of Alzheimer disease

Tanzi, R. E. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006296 · Cited by 727 · see citing works

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

Genin, E., Hannequin, D., Wallon, D., Sleegers, K., Hiltunen, M., Combarros, O., Bullido, M. J., Engelborghs, S., De Deyn, P., Berr, C., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.52 · Cited by 714 · see citing works

A High-Density Whole-Genome Association Study Reveals That APOE Is the Major Susceptibility Gene for Sporadic Late-Onset Alzheimer's Disease

Coon, K. D., Myers, A. J., Craig, D. W., Webster, J. A., Pearson, J. V., Lince, D. H., Zismann, V. L., Beach, T. G., Leung, D., Bryden, L., et al. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0419 · Cited by 569 · see citing works

Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

Bertram, L., Lange, C., Mullin, K., Parkinson, M., Hsiao, M., Hogan, M. F., Schjeide, B. M. M., Hooli, B., DiVito, J., Ionita, I., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.10.008 · Cited by 511 · see citing works

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

Li, H., Wetten, S., Li, L., St. Jean, P. L., Upmanyu, R., Surh, L., Hosford, D., Barnes, M. R., Briley, J. D., Borrie, M., et al. (2008) · Archives of Neurology · doi:10.1001/archneurol.2007.3 · Cited by 499 · see citing works

A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

Fede, G. D., Catania, M., Morbin, M., Rossi, G., Suardi, S., Mazzoleni, G., Merlin, M., Gıovagnolı, A. R., Prioni, S., Erbetta, A., et al. (2009) · Science · doi:10.1126/science.1168979 · Cited by 415 · see citing works

Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease

Martins, I. J., Hone, E., Foster, J. K., Sünram-Lea, S. I., Gnjec, A., Fuller, S. J., Nolan, D., Gandy, S. E., & Martins, R. N. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001854 · Cited by 388 · see citing works

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

Potkin, S. G., Guffanti, G., Lakatos, A., Turner, J. A., Kruggel, F., Fallon, J. H., Saykin, A. J., Orro, A., Lupoli, S., Salvi, E., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006501 · Cited by 376 · see citing works

Clathrin Assembly Lymphoid Myeloid Leukemia (CALM) Protein: Localization in Endocytic-coated Pits, Interactions with Clathrin, and the Impact of Overexpression on Clathrin-mediated Traffic

Tebar, F., Bohlander, S. K., & Sorkin, A. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.8.2687 · Cited by 320 · see citing works

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer’s disease

Carrasquillo, M. M., Zou, F., Pankratz, V. S., Wilcox, S. L., Ma, L., Walker, L. P., Younkin, S. G., Younkin, C. S., Younkin, L. H., Bisceglio, G. D., et al. (2009) · Nature Genetics · doi:10.1038/ng.305 · Cited by 296 · see citing works

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

Grupe, A., Abraham, R., Li, Y., Rowland, C., Hollingworth, P., Morgan, A., Jehu, L., Segurado, R., Stone, D., Schadt, E., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm031 · Cited by 289 · see citing works

Epigenetic regulation in the pathophysiology of Alzheimer's disease

Chouliaras, L., Rutten, B. P. F., Kenis, G., Peerbooms, O., Visser, P. J., Verhey, F., van Os, J., Steinbusch, H. W. M., & van den Hove, D. L. A. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.01.002 · Cited by 262 · see citing works

Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

Beecham, G. W., Martin, E. R., Li, Y.-J., Slifer, M. A., Gilbert, J. R., Haines, J. L., & Pericak-Vance, M. A. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.12.008 · Cited by 260 · see citing works

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin–1 gene

Larner, A. J., & Doran, M. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0019-5 · Cited by 256 · see citing works

Alzheimer’s disease phenotypes and genotypes associated with mutations in presenilin 2

Jayadev, S., Leverenz, J. B., Steinbart, E. J., Stahl, J. H., Klunk, W. E., Yu, C.-E., & Bird, T. D. (2010) · Brain · doi:10.1093/brain/awq033 · Cited by 246 · see citing works

Role of ATP‐binding cassette transporters in brain lipid transport and neurological disease

Kim, W. S., Weickert, C. S., & Garner, B. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05099.x · Cited by 237 · see citing works

A Cortactin-CD2-associated Protein (CD2AP) Complex Provides a Novel Link between Epidermal Growth Factor Receptor Endocytosis and the Actin Cytoskeleton

Lynch, D. K., Winata, S. C., Lyons, R. J., Hughes, W. E., Lehrbach, G. M., Wasinger, V. C., Corthals, G. L., Cordwell, S. J., & Daly, R. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211407200 · Cited by 227 · see citing works

Complement Receptor 1: Disease associations and therapeutic implications

Khera, R., & Das, N. (2008) · Molecular Immunology · doi:10.1016/j.molimm.2008.09.026 · Cited by 213 · see citing works

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

Jehle, A. W., Gardai, S. J., Li, S., Linsel‐Nitschke, P., Morimoto, K., Janssen, W. J., Vandivier, R. W., Wang, N., Greenberg, S., Dale, B. M., et al. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200601030 · Cited by 213 · see citing works

Distribution of clusterin in Alzheimer brain tissue

McGeer, P. L., Kawamata, T., & Walker, D. G. (1992) · Brain Research · doi:10.1016/0006-8993(92)90071-g · Cited by 212 · see citing works

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

Abraham, R., Moskvina, V., Sims, R., Hollingworth, P., Morgan, A., Georgieva, L., Dowzell, K., Cichon, S., Hillmer, A. M., O'Donovan, M. C., et al. (2008) · BMC Medical Genomics · doi:10.1186/1755-8794-1-44 · Cited by 195 · see citing works

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

Lai, K., & Ip, N. Y. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.04.009 · Cited by 191 · see citing works

Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals

Lee, J. H., Cheng, R., Barral, S., Reitz, C., Medrano, M., Lantigua, R., Jiménez-Velazquez, I. Z., Rogaeva, E., St. George-Hyslop, P. H., & Mayeux, R. (2011) · Archives of Neurology · doi:10.1001/archneurol.2010.292 · Cited by 190 · see citing works

Functions and malfunctions of the tau proteins

Shahani, N., & Brandt, R. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/pl00012495 · Cited by 171 · see citing works

Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells

Kim, W., Guillemin, G., Glaros, E., Lim, C. K., & Garner, B. (2006) · NeuroReport · doi:10.1097/01.wnr.0000221833.41340.cd · Cited by 158 · see citing works

Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: Patterns of linkage disequilibrium and disease/marker association

Yu, C., Seltman, H. J., Peskind, E. R., Galloway, N. M., Zhou, P. X., Rosenthal, E. A., Wijsman, E. M., Tsuang, D. W., Devlin, B., & Schellenberg, G. D. (2007) · Genomics · doi:10.1016/j.ygeno.2007.02.002 · Cited by 155 · see citing works

Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities

Naj, A. C., Beecham, G. W., Martin, E. R., Gallins, P. J., Powell, E. H., Konidari, I., Whitehead, P. L., Cai, G., Haroutunian, V. H., Scott, W. K., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001130 · Cited by 147 · see citing works

Evidence for CALM in Directing VAMP2 Trafficking

Harel, A., Wu, F., Mattson, M. P., Morris, C. M., & Yao, P. J. (2008) · Traffic · doi:10.1111/j.1600-0854.2007.00694.x · Cited by 144 · see citing works

Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

Smith, S. M., Renden, R., & von Gersdorff, H. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.08.005 · Cited by 143 · see citing works

Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease

Varvel, N. H., Bhaskar, K., Patil, A. R., Pimplikar, S. W., Herrup, K., & Lamb, B. T. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2441-08.2008 · Cited by 138 · see citing works

Abca7 Null Mice Retain Normal Macrophage Phosphatidylcholine and Cholesterol Efflux Activity despite Alterations in Adipose Mass and Serum Cholesterol Levels

Kim, W. S., Fitzgerald, M. L., Kang, K., Okuhira, K., Bell, S. A., Manning, J. J., Koehn, S. L., Lu, N., Moore, K. J., & Freeman, M. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412602200 · Cited by 137 · see citing works

Multiple Receptors Mediate apoJ-Dependent Clearance of Cellular Debris into Nonprofessional Phagocytes

Bartl, M. M., Luckenbach, T., Bergner, O., Ullrich, O., & Koch-Brandt, C. (2001) · Experimental Cell Research · doi:10.1006/excr.2001.5358 · Cited by 132 · see citing works

Genome-Wide Scan of Copy Number Variation in Late-Onset Alzheimer's Disease

Heinzen, E. L., Need, A. C., Hayden, K. M., Chiba‐Falek, O., Roses, A. D., Strittmatter, W. J., Burke, J. R., Hulette, C. M., Welsh-Bohmer, K. A., & Goldstein, D. B. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1212 · Cited by 129 · see citing works

Examination of the current top candidate genes for AD in a genome-wide association study

Feulner, T. M., Laws, S. M., Friedrich, P., Wagenpfeil, S., Wurst, S. H. R., Riehle, C., Kuhn, K. A., Krawczak, M., Schreiber, S., Nikolaus, S., et al. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.141 · Cited by 128 · see citing works

Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity

Tateno, H., Li, H., Schur, M. J., Bovin, N. V., Crocker, P. R., Wakarchuk, W. W., & Paulson, J. C. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00383-07 · Cited by 123 · see citing works

Cerebral glucose metabolism in patients with AD and different <i>APOE</i> genotypes

Drzezga, A., Riemenschneider, M., Strassner, B., Grimmer, T., Peller, M., Knoll, A., Wagenpfeil, S., Minoshima, S., Schwaiger, M., & Kurz, A. (2005) · Neurology · doi:10.1212/01.wnl.0000148478.39691.d3 · Cited by 116 · see citing works

The three new pathways leading to Alzheimer's disease

Morgan, K. (2011) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.2011.01181.x · Cited by 112 · see citing works

Functions of ephrin/Eph interactions in the development of the nervous system: Emphasis on the hippocampal system

Martı́nez, A., & Soriano, E. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.02.001 · Cited by 110 · see citing works

Genetics of Alzheimer disease in the pre- and post-GWAS era

Ertekin‐Taner, N. (2010) · Alzheimer s Research & Therapy · doi:10.1186/alzrt26 · Cited by 107 · see citing works

Clusterin in cerebrospinal fluid: analysis of carbohydrates and quantification of native and glycosylated forms

Nilselid, A.-M., Davidsson, P., Nägga, K., Andreasen, N., Fredman, P., & Blennow, K. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2005.12.005 · Cited by 104 · see citing works

Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation

Rossor, M. N., Fox, N. C., Beck, J. A., Campbell, T., & Collinge, J. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90715-1 · Cited by 96 · see citing works

Genome screen of late‐onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis

Poduslo, S. E., Huang, R., Huang, J., & Smith, S. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30767 · Cited by 80 · see citing works

Alzheimer dementia caused by a novel mutation located in the APP C-terminal intracytosolic fragment

Theuns, J., Marjaux, E., Vandenbulcke, M., Laere, K. V., Kumar‐Singh, S., Bormans, G. M., Brouwers, N., den Broeck, M. V., Vennekens, K. M., Corsmit, E., et al. (2006) · Human Mutation · doi:10.1002/humu.20402 · Cited by 78 · see citing works

Functional MAPT haplotypes: Bridging the gap between genotype and neuropathology

Caffrey, T. M., & Wade‐Martins, R. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.04.006 · Cited by 78 · see citing works

Clinical and pathological features of an Alzheimer's disease patient with the MAPT ΔK280 mutation

Momeni, P., Pittman, A. M., Lashley, T., Vandrovcová, J., Malzer, E., Luk, C. Y., Hulette, C., Lees, A. J., Révész, T., Hardy, J., et al. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.07.013 · Cited by 66 · see citing works

Mutational analysis of TARDBP in neurodegenerative diseases

Ticozzi, N., LeClerc, A. L., van Blitterswijk, M., Keagle, P. J., McKenna-Yasek, D. M., Sapp, P. C., Silani, V., Wills, A.-M. A., Brown, R. H., & Landers, J. E. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.11.018 · Cited by 62 · see citing works

Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.

Miklossy, J., Taddei, K., Suvà, D., Verdile, G., Fonte, J., Fisher, C. M., Gnjec, A., Ghika, J., Suard, F., Mehta, P., et al. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00192-6 · Cited by 60 · see citing works

The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)

Meunier, B., Quaranta, M., Daviet, L., Hatzoglou, A., & Leprince, C. (2008) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2008.08.006 · Cited by 59 · see citing works

Identification of Novel Candidate Genes for Alzheimer's Disease by Autozygosity Mapping using Genome Wide SNP Data

Sherva, R., Baldwin, C. T., Inzelberg, R., Vardarajan, B. N., Cupples, L. A., Lunetta, K. L., Bowirrat, A., Naj, A. C., Pericak‐Vance, M. A., Friedland, R. P., et al. (2011) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100714 · Cited by 56 · see citing works

Evidence Linking Genetics, Environment, and Epigenetics to Impaired DNA Repair in Alzheimer's Disease

Coppedè, F., & Migliore, L. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1415 · Cited by 53 · see citing works

Familial Early-Onset Dementia With Tau Intron 10 + 16 Mutation With Clinical Features Similar to Those of Alzheimer Disease

Doran, M., du Plessis, D., Ghadiali, E. J., Mann, D. M. A., Pickering-Brown, S. M., & Larner, A. J. (2007) · Archives of Neurology · doi:10.1001/archneur.64.10.1535 · Cited by 39 · see citing works

Pathological and clinical heterogeneity of presenilin 1 gene mutations

Menéndez‐González, M. (2004) · Journal of Alzheimer s Disease · doi:10.3233/jad-2004-6503 · Cited by 29 · see citing works

Monogenic determinants of familial Alzheimer's disease: presenilin-2 mutations

Renbaum, P., & Levy‐Lahad, E. (1998) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050220 · Cited by 24 · see citing works

Contribution of TARDBP to Alzheimer's Disease Genetic Etiology

Brouwers, N., Bettens, K., Gijselinck, I., Engelborghs, S., Pickut, B. A., Miegroet, H. V., Montoya, A. G., Mattheijssens, M., Peeters, K., Deyn, P. P. D., et al. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100198 · Cited by 23 · see citing works

Mutation Negative “Early-onset Familial Alzheimer Disease”: Consider Screening for Tau Gene Mutations

Larner, A. J. (2008) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e3181664ea4 · Cited by 20 · see citing works

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases

Chin-Chan, M., Navarro-Yepes, J., & Quintanilla‐Vega, B. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00124 · Cited by 712 · see citing works

Pathogenesis, diagnostics, and therapeutics for Alzheimer's disease: Breaking the memory barrier

Tryphena, K. P., Shukla, R., Khatri, D. K., & Vora, L. K. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102481 · Cited by 418 · see citing works

The Role of NADPH Oxidases and Oxidative Stress in Neurodegenerative Disorders

Tarafdar, A., & Pula, G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123824 · Cited by 373 · see citing works

Alzheimer’s disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs

Monteiro, A. R., Barbosa, D. J., Remião, F., & Silva, R. V. D. S. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115522 · Cited by 358 · see citing works

Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

Liu, S., Fan, M., Xu, J.-X., Yang, L.-J., Qi, C.-C., Xia, Q.-R., & Ge, J.-F. (2022) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02393-2 · Cited by 296 · see citing works

A study on the association between infectious burden and A lzheimer's disease

Bu, X., Yao, X., Jiao, S. ‐., Zeng, F., Liu, Y. ‐., Xiang, Y., Liang, C. ‐., Wang, Q. ‐., Wang, X., Cao, H., et al. (2014) · European Journal of Neurology · doi:10.1111/ene.12477 · Cited by 273 · see citing works

Impact of HMGB1, RAGE, and TLR4 in Alzheimer’s Disease (AD): From Risk Factors to Therapeutic Targeting

Paudel, Y. N., Angelopoulou, E., Piperi, C., Othman, I., Aamir, K., & Shaikh, M. F. (2020) · Cells · doi:10.3390/cells9020383 · Cited by 257 · see citing works

Neuroprotective effects of resveratrol in Alzheimer disease pathology

Rege, S. D., Geetha, T., Griffin, G. D., Broderick, T. L., & Babu, J. R. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00218 · Cited by 243 · see citing works

Calcium Dyshomeostasis in Alzheimer’s Disease Pathogenesis

Cascella, R., & Cecchi, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094914 · Cited by 189 · see citing works

Neural oscillations and brain stimulation in Alzheimer’s disease

Jafari, Z., Kolb, B. E., & Mohajerani, M. H. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101878 · Cited by 176 · see citing works

Exosomes in Alzheimer's disease

Malm, T., Loppi, S. H., & Kanninen, K. M. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.04.011 · Cited by 152 · see citing works

Metals and Neuronal Metal Binding Proteins Implicated in Alzheimer’s Disease

Cristóvão, J. S., Santos, R., & Gomes, C. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/9812178 · Cited by 146 · see citing works

β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View

Penke, B., Bogár, F., & Fülöp, L. (2017) · Molecules · doi:10.3390/molecules22101692 · Cited by 135 · see citing works

Healthy Aging and Dementia: Two Roads Diverging in Midlife?

Irwin, K. E., Sexton, C. E., Daniel, T., LAWLOR, B. A., & Naçi, L. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00275 · Cited by 118 · see citing works

The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review

Wen, K., Milić, J., El‐Khodor, B. F., Dhana, K., Nano, J., Pulido, T., Kraja, B., Začiragić, A., Bramer, W. M., Troup, J., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167201 · Cited by 122 · see citing works

Emerging risk of environmental factors: insight mechanisms of Alzheimer’s diseases.

Rahman, M. A., Rahman, M. S., Uddin, M. J., Mamum-Or-Rashid, A. N. M., Pang, M.-G., & Rhim, H. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08243-z · Cited by 115 · see citing works

Role of miRNAs in Alzheimer’s Disease and Possible Fields of Application

Silvestro, S., Bramanti, P., & Mazzon, E. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163979 · Cited by 112 · see citing works

Direct Visualization of Fungal Infection in Brains from Patients with Alzheimer's Disease

Pisa, D., Alonso, R., Juarranz, Á., Rábano, A., & Carrasco, L. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-141386 · Cited by 111 · see citing works

Amyloid Beta and MicroRNAs in Alzheimer’s Disease

Amakiri, N., Kubosumi, A., Tran, J., & Reddy, P. H. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00430 · Cited by 107 · see citing works

Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum

Ríos, J. A., Cisternas, P., Arrese, M. A., Salesa Barja, Y., & Inestrosa, N. C. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.07.004 · Cited by 104 · see citing works

Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis

Fedele, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914499 · Cited by 102 · see citing works

Translation of Pre-Clinical Studies into Successful Clinical Trials for Alzheimer’s Disease: What are the Roadblocks and How Can They Be Overcome?

Banik, A., Brown, R. E., Bamburg, J., Lahiri, D. K., Khurana, D., Friedland, R. P., Chen, W., Ding, Y., Mudher, A., Padjen, A. L., et al. (2015) · Journal of Alzheimer’s Disease · doi:10.3233/jad-150136 · Cited by 102 · see citing works

Synaptic plasticity in Alzheimer’s disease and healthy aging

Torres, D. M. C., & Cárdenas, F. P. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2019-0058 · Cited by 98 · see citing works

Anti-Viral Properties of Amyloid-β Peptides

Bourgade, K., Dupuis, G., Frost, E. H., & Fülöp, T. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-160517 · Cited by 96 · see citing works

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

Walker, D. G., Whetzel, A. M., Serrano, G., Sue, L. I., Beach, T. G., & Lue, L.-F. (2015) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.09.023 · Cited by 93 · see citing works

Noise exposure accelerates the risk of cognitive impairment and Alzheimer’s disease: Adulthood, gestational, and prenatal mechanistic evidence from animal studies

Jafari, Z., Kolb, B. E., & Mohajerani, M. H. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.04.001 · Cited by 91 · see citing works

A monomeric polysaccharide from Polygonatum sibiricum improves cognitive functions in a model of Alzheimer's disease by reshaping the gut microbiota

Luo, S., Zhang, X., Huang, S. Q., Feng, X., Zhang, X., & Xiang, D.-X. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.05.185 · Cited by 92 · see citing works

Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling

Wan, W., Cao, L., Kalionis, B., Murthi, P., Xia, S., & Guan, Y. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00607 · Cited by 84 · see citing works

Alzheimer’s Disease: Pathogenesis and Therapeutic Interventions

Ogbodo, J. O., Agbo, C. P., Njoku, U. O., Ogugofor, M. O., Egba, S. I., Ihim, S. A., Echezona, A. C., Brendan, K. C., Upaganlawar, A. B., & Upasani, C. D. (2021) · Current Aging Science · doi:10.2174/1874609814666210302085232 · Cited by 84 · see citing works

The Application of Artificial Intelligence in the Genetic Study of Alzheimer’s Disease

Mishra, R., & Li, B. (2020) · Aging and Disease · doi:10.14336/ad.2020.0312 · Cited by 81 · see citing works

Epigenetics, a key for unlocking complex CNS disorders? Therapeutic implications

Szyf, M. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2014.01.009 · Cited by 76 · see citing works

Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory

Kasza, Á., Penke, B., Frank, Z., Bozsó, Z., Szegedi, V., Hunya, Á. G., Németh, K., Kozma, G., & Fülöp, L. (2017) · Molecules · doi:10.3390/molecules22112007 · Cited by 75 · see citing works

O-GlcNAcylation as a Therapeutic Target for Alzheimer’s Disease

Park, J., Lai, M. K. P., Arumugam, T. V., & Jo, D. (2020) · NeuroMolecular Medicine · doi:10.1007/s12017-019-08584-0 · Cited by 75 · see citing works

Dimethyl fumarate attenuates intracerebroventricular streptozotocin-induced spatial memory impairment and hippocampal neurodegeneration in rats

Majkutewicz, I., Kurowska, E., Podlacha, M., Myślińska, D., Grembecka, B., Ruciński, J., Plucińska, K., Jerzemowska, G., & Wrona, D. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.04.012 · Cited by 75 · see citing works

Insulin resistance, neuroinflammation, and Alzheimer’s disease

Najem, D., Bamji‐Mirza, M., Chang, N., Liu, Q. Y., & Zhang, W. (2014) · Reviews in the Neurosciences · doi:10.1515/revneuro-2013-0050 · Cited by 75 · see citing works

MicroRNAs as diagnostic and therapeutic tools for Alzheimer’s disease: advances and limitations

Peplow, P., & Martinez, B. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.244784 · Cited by 72 · see citing works

The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation

Paris, D., Ait-Ghezala, G., Bachmeier, C., Laco, G., Beaulieu-Abdelahad, D., Lin, Y., Jin, C., Crawford, F., & Mullan, M. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.608091 · Cited by 73 · see citing works

Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer’s tau pathology

Huang, S., Zhang, Z., Cao, J., Yu, Y., & Pei, G. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01006-x · Cited by 72 · see citing works

Effects of vanillic acid on Aβ1-40-induced oxidative stress and learning and memory deficit in male rats

Ahmadi, N., Safari, S., Mirazi, N., Karimi, S. A., & Komaki‬, A. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.02.024 · Cited by 71 · see citing works

Utility and validity of DISC1 mouse models in biological psychiatry

Tomoda, T., Sumitomo, A., Jaaro-Peled, H., & Sawa, A. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.061 · Cited by 68 · see citing works

Amyloid accumulation is a late event in sporadic Alzheimer's disease-like pathology in nontransgenic rats

Stefanova, N. A., Muraleva, N. A., Korbolina, E. E., Владимировна, К. Е., Maksimova, K. Y., & Kolosova, N. G. (2014) · Oncotarget · doi:10.18632/oncotarget.2751 · Cited by 66 · see citing works

Progranulin polymorphism rs5848 is associated with increased risk of Alzheimer's disease

Sheng, J., Su, L., Xu, Z., & Chen, G. (2014) · Gene · doi:10.1016/j.gene.2014.03.041 · Cited by 64 · see citing works

Inhibition of Aquaporin 4 Decreases Amyloid Aβ40 Drainage Around Cerebral Vessels

Roşu, G. C., Cătălin, B., Bălşeanu, T. A., Mogoantă, L., Mărgăritescu, C., Kumar‐Singh, S., & Pirici, D. N. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02044-8 · Cited by 65 · see citing works

Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s Disease

Janota, C. S., Lemere, C. A., & Brito, M. A. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9319-7 · Cited by 65 · see citing works

Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions

Toh, W. H., & Gleeson, P. A. (2016) · Biochemical Journal · doi:10.1042/bcj20160147 · Cited by 62 · see citing works

NK Cells are Activated in Amnestic Mild Cognitive Impairment but not in Mild Alzheimer’s Disease Patients

Page, A. Y. L., Bourgade, K., Lamoureux, J., Frost, E. H., Pawelec, G., Larbi, A., Witkowski, J. M., Dupuis, G., & Fülöp, T. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-143054 · Cited by 63 · see citing works

Functional and Phenotypic Diversity of Microglia: Implication for Microglia-Based Therapies for Alzheimer’s Disease

Xu, Y., Au, N. P. B., & Ma, C. H. E. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.896852 · Cited by 63 · see citing works

Liposome-Derived Nanosystems for the Treatment of Behavioral and Neurodegenerative Diseases: The Promise of Niosomes, Transfersomes, and Ethosomes for Increased Brain Drug Bioavailability

Pires, P. C., Paiva‐Santos, A. C., & Veiga, F. (2023) · Pharmaceuticals · doi:10.3390/ph16101424 · Cited by 59 · see citing works

Upregulation of AMPK Ameliorates Alzheimer’s Disease-Like Tau Pathology and Memory Impairment

Wang, L., Li, N., Shi, F.-X., Xu, W., Cao, Y., Lei, Y., Wang, J., Tian, Q., & Zhou, X. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-01955-w · Cited by 57 · see citing works

Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2

Galla, L., Redolfi, N., Pozzan, T., Pizzo, P., & Greotti, E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030770 · Cited by 57 · see citing works

JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer’s disease

Scopa, C., Barnada, S. M., Cicardi, M. E., Singer, M., Trotti, D., & Trizzino, M. (2023) · Nature Communications · doi:10.1038/s41467-023-43728-8 · Cited by 58 · see citing works

Long-term effects of amyloid-beta deposits in human iPSC-derived astrocytes

Konstantinidis, E., Dakhel, A., Beretta, C., & Erlandsson, A. (2023) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2023.103839 · Cited by 55 · see citing works

Genetic Phenotypes of Alzheimer’s Disease: Mechanisms and Potential Therapy

Quan, M., Cao, S., Wang, Q., Wang, S., & Jia, J. (2023) · Phenomics · doi:10.1007/s43657-023-00098-x · Cited by 60 · see citing works

Clinical and Preclinical Studies of Fermented Foods and Their Effects on Alzheimer’s Disease

Kumar, M. R., Azizi, N. F., Yeap, S. K., Abdullah, J. O., Khalid, M., Omar, A. R., Osman, M. A., Leow, T. C., Mortadza, S. A. S., & Alitheen, N. B. (2022) · Antioxidants · doi:10.3390/antiox11050883 · Cited by 53 · see citing works

Grape seed proanthocyanidins ameliorate neuronal oxidative damage by inhibiting GSK-3β-dependent mitochondrial permeability transition pore opening in an experimental model of sporadic Alzheimer’s disease

Sun, Q., Jia, N., Li, X., Yang, J., & Chen, G. (2019) · Aging · doi:10.18632/aging.102041 · Cited by 53 · see citing works

Redox signaling and metabolism in Alzheimer's disease

Holubiec, M. I., Gellert, M., & Hanschmann, E.-M. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1003721 · Cited by 52 · see citing works

Lipidomics of Alzheimer’s Disease

Touboul, D., & Gaudin, M. (2014) · Bioanalysis · doi:10.4155/bio.13.346 · Cited by 52 · see citing works

Bilateral intracerebroventricular injection of streptozotocin induces AD-like behavioral impairments and neuropathological features in mice: Involved with the fundamental role of neuroinflammation

Fan, M., Liu, S., Sun, H.-M., Ma, M.-D., Gao, Y.-J., Qi, C.-C., Xia, Q.-R., & Ge, J.-F. (2022) · Biomedicine &amp; Pharmacotherapy · doi:10.1016/j.biopha.2022.113375 · Cited by 50 · see citing works

Brain aging: A Ianus‐faced player between health and neurodegeneration

Vanni, S., Baldeschi, A. C., Zattoni, M., & Legname, G. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24379 · Cited by 45 · see citing works

Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease

Perez, S. E., Nadeem, M., He, B., Miguel, J. C., Malek‐Ahmadi, M. H., Chen, K., & Mufson, E. J. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.02.012 · Cited by 49 · see citing works

The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer’s disease

Fronza, M. G., Alves, D. A. C., Praticò, D., & Savegnago, L. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102033 · Cited by 47 · see citing works

Aluminum chloride and D-galactose induced a zebrafish model of Alzheimer's disease with cognitive deficits and aging

Luo, L., Yan, T., Yang, L., & Zhao, M. (2024) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2024.05.036 · Cited by 55 · see citing works

The Effects of Gene-Environment Interactions Between Cadmium Exposure and Apolipoprotein E4 on Memory in a Mouse Model of Alzheimer’s Disease

Zhang, L., Wang, H., Abel, G. M., Storm, D. R., & Xia, Z. (2019) · Toxicological Sciences · doi:10.1093/toxsci/kfz218 · Cited by 48 · see citing works

The Brilliance of the Zebrafish Model: Perception on Behavior and Alzheimer’s Disease

Shenoy, A., Banerjee, M., Upadhya, A., Bagwe‐Parab, S., & Kaur, G. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.861155 · Cited by 47 · see citing works

Potential Role of Glucagon-like Peptide-1 Receptor Agonists in the Treatment of Cognitive Decline and Dementia in Diabetes Mellitus

Pelle, M. C., Zaffina, I., Giofrè, F., Pujia, R., & Arturi, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411301 · Cited by 49 · see citing works

Selenium-containing compounds: a new hope for innovative treatments in Alzheimer’s disease and Parkinson’s disease

Pyka, P., Garbo, S., Fioravanti, R., Jacob, C., Hittinger, M., Handzlik, J., Zwergel, C., & Battistelli, C. (2024) · Drug Discovery Today · doi:10.1016/j.drudis.2024.104062 · Cited by 46 · see citing works

Molecular Targets in Alzheimer’s Disease

Bjørklund, G., Aaseth, J., Dadar, M., & Chirumbolo, S. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1563-9 · Cited by 46 · see citing works

Prepulse inhibition of the acoustic startle reflex and P50 gating in aging and alzheimer’s disease

Jafari, Z., Kolb, B. E., & Mohajerani, M. H. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101028 · Cited by 42 · see citing works

Whole‐exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer's disease

Patel, T., Brookes, K. J., Turton, J. C., Chaudhury, S., Guetta‐Baranes, T., Guerreiro, R. J., Brás, J., Hernandez, D. G., Singleton, A., Francis, P. T., et al. (2017) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12452 · Cited by 46 · see citing works

5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

Klein, C., Roussel, G., Brun, S., Rusu, C., Patte‐Mensah, C., Maître, M., & Mensah‐Nyagan, A. G. (2018) · Acta Neuropathologica Communications · doi:10.1186/s40478-018-0640-z · Cited by 44 · see citing works

Morphological and Molecular Profiling of Amyloid-β Species in Alzheimer’s Pathogenesis

Almeida, Z. L., Vaz, D. C., & Brito, R. M. M. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04543-4 · Cited by 45 · see citing works

KCa3.1 constitutes a pharmacological target for astrogliosis associated with Alzheimer's disease

Yi, M., Yu, P., Lu, Q., Geller, H. M., Yu, Z., & Chen, H. (2016) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2016.08.008 · Cited by 43 · see citing works

Deep Learning-Based Eye-Tracking Analysis for Diagnosis of Alzheimer's Disease Using 3D Comprehensive Visual Stimuli

Zuo, F., Jing, P., Sun, J., Duan, J., Ji, Y., & Liu, Y. (2024) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2024.3365172 · Cited by 42 · see citing works

Imaging markers of structural and functional brain changes that precede cognitive symptoms in risk for Alzheimer’s disease

Burggren, A. C., & Brown, J. A. (2013) · Brain Imaging and Behavior · doi:10.1007/s11682-013-9278-4 · Cited by 42 · see citing works

Impacts of oxidants and antioxidants on the emergence and progression of Alzheimer's disease

Goshtasbi, H., Pakchin, P. S., Movafeghi, A., Barar, J., Castejon, A. M., Omidian, H., & Omidi, Y. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105268 · Cited by 43 · see citing works

A New Fluorogenic Small-Molecule Labeling Tool for Surface Diffusion Analysis and Advanced Fluorescence Imaging of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Based on Silicone Rhodamine: SiR-BACE1

Karch, S., Broichhagen, J., Schneider, J., Böning, D., Hartmann, S., Schmid, B., Tripal, P., Palmisano, R., Alzheimer, C., Johnsson, K., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00387 · Cited by 39 · see citing works

The Potential Role of Herpes Simplex Virus Type 1 and Neuroinflammation in the Pathogenesis of Alzheimer's Disease

Laval, K., & Enquist, L. W. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.658695 · Cited by 40 · see citing works

Epigenetic Modifications in Alzheimer's Disease: Cause or Effect?

Piaceri, I., Raspanti, B., Tedde, A., Bagnoli, S., Sorbi, S., & Nacmias, B. (2014) · Journal of Alzheimer s Disease · doi:10.3233/jad-141452 · Cited by 39 · see citing works

Hearing Loss in Neurological Disorders

Li, S., Cheng, C., Lü, L., Ma, X., Zhang, X., Li, A., Chen, J., Qian, X., & Gao, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.716300 · Cited by 39 · see citing works

Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer’s disease

Ramezani, M., Fernando, M. G., Eslick, S., Asih, P. R., Shadfar, S., Bandara, E. M. S., Hillebrandt, H., Meghwar, S., Shahriari, M., Chatterjee, P., et al. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1297984 · Cited by 38 · see citing works

Strategies for modeling aging and age-related diseases

Jothi, D., & Kulka, L. A. M. (2024) · npj Aging · doi:10.1038/s41514-024-00161-5 · Cited by 36 · see citing works

Aducanumab and Its Effects on Tau Pathology: Is This the Turning Point of Amyloid Hypothesis?

Silvestro, S., Valeri, A., & Mazzon, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042011 · Cited by 35 · see citing works

Types of memory, dementia, Alzheimer’s disease, and their various pathological cascades as targets for potential pharmacological drugs

Akhtar, A., Singh, S., Kaushik, R., Awasthi, R., & Behl, T. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102289 · Cited by 37 · see citing works

SMPD3 deficiency perturbs neuronal proteostasis and causes progressive cognitive impairment

Stoffel, W., Jenke, B., Schmidt‐Soltau, I., Binczek, E., Brodesser, S., & Hammels, I. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0560-7 · Cited by 34 · see citing works

Elevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease

Xu, C., Liu, G., Ji, H., Chen, W., Dai, D., Chen, Z., Zhou, D., Xu, L., Hu, H., Cui, W., et al. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9424 · Cited by 34 · see citing works

Multifaceted Alzheimer’s Disease: Building a Roadmap for Advancement of Novel Therapies

Kaur, D., Behl, T., Sehgal, A., Singh, S., Sharma, N., & BUNGAU, S. G. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03415-w · Cited by 34 · see citing works

MicroRNAs and MAPKs: Evidence of These Molecular Interactions in Alzheimer’s Disease

Raffaele, I., Silvestro, S., & Mazzon, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24054736 · Cited by 33 · see citing works

AMPK Ameliorates Tau Acetylation and Memory Impairment Through Sirt1

Wang, L., Shi, F.-X., Li, N., Cao, Y., Lei, Y., Wang, J., Tian, Q., & Zhou, X. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02079-x · Cited by 33 · see citing works

Examination of the Effect of Rare Variants in <i>TREM2</i> , <i>ABI3</i> , and <i>PLCG2</i> in LOAD Through Multiple Phenotypes

Olive, C., Ibanez, L., Farias, F. H. G., Wang, F., Budde, J. P., Norton, J. B., Gentsch, J., Morris, J. C., Li, Z., Dube, U., et al. (2020) · Journal of Alzheimer’s Disease · doi:10.3233/jad-200019 · Cited by 32 · see citing works

Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Perspectives

Anwar, S., Alharbi, H., Babiker, A., & Rahmani, A. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062681 · Cited by 35 · see citing works

Cholesterol and Dementia: A Long and Complicated Relationship

McFarlane, O., & Kędziora–Kornatowska, K. (2019) · Current Aging Science · doi:10.2174/1874609812666190917155400 · Cited by 31 · see citing works

BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer’s disease models

Nishioka, H., Tooi, N., Isobe, T., Nakatsuji, N., & Aiba, K. (2016) · Scientific Reports · doi:10.1038/srep33427 · Cited by 31 · see citing works

Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model

Li, W., Li, K., Gao, J. Q., & Yang, Z. R. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-017-0756-2 · Cited by 30 · see citing works

Novel fluid biomarkers to differentiate frontotemporal dementia and dementia with Lewy bodies from Alzheimer's disease: A systematic review

Chaudhry, A., Houlden, H., & Rizig, M. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.116886 · Cited by 30 · see citing works

Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments

Coronas‐Samano, G., Baker, K. L., Tan, W. J. T., Ivanova, A. V., & Verhagen, J. V. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00268 · Cited by 29 · see citing works

Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC‐derived models of Alzheimer's disease

Salcedo, C., Garcia, V. P., García‐Adán, B., Ameen, A. O., Gegelashvili, G., Waagepetersen, H. S., Freude, K., & Aldana, B. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.16014 · Cited by 28 · see citing works

Alzheimer's Disease: A Review of Pathology, Current Treatments, and the Potential Therapeutic Effect of Decreasing Oxidative Stress by Combined Vitamin D and l -Cysteine Supplementation

Jain, S. K., Stevens, C. M., Margret, J. J., & Levine, S. N. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0245 · Cited by 27 · see citing works

A Rat Model of Alzheimer’s Disease Based on Abeta42 and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems

Petrásek, T., Škurlová, M., Malenínská, K., Vojtěchová, I., Krištofíková, Z., Matušková, H., Šírová, J., Valeš, K., Řı́pová, D., & Stuchlı́k, A. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00083 · Cited by 27 · see citing works

Into the Fourth Dimension: Dysregulation of Genome Architecture in Aging and Alzheimer’s Disease

Winick‐Ng, W., & Rylett, R. J. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00060 · Cited by 25 · see citing works

Genetic risk factors of Alzheimer's disease

Foltýnová, A. (2018) · Digital Repository (National Repository of Grey Literature)

Molecular genetics of Alzheimer's disease: An update

Brouwers, N., Sleegers, K., & Broeckhoven, C. V. (2008) · Annals of Medicine · doi:10.1080/07853890802186905 · Cited by 208 · see citing works

Molecular genetics of Alzheimer's disease.

Am, G. (1997) · PubMed · Cited by 16 · see citing works

Alzheimer’s Disease: An Updated Overview of Its Genetics

Andrade-Guerrero, J., Santiago-Balmaseda, A., Jeronimo-Aguilar, P., Vargas-Rodríguez, I., Cadena-Suárez, A. R., Sánchez-Garibay, C., Pozo-Molina, G., Méndez-Catalá, C. F., Cardenas-Aguayo, M.-D.-C., Diaz-Cintra, S., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043754 · Cited by 336 · see citing works

Causative and susceptibility genes for Alzheimer’s disease: a review

Rocchi, A., Pellegrini, S., Siciliano, G., & Murri, L. (2003) · Brain Research Bulletin · doi:10.1016/s0361-9230(03)00067-4 · Cited by 319 · see citing works