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Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing
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5xFAD mice display AD-like memory deficits at 12 months of age.
“Previously, it has been shown that 5xFAD mice display AD-like memory deficits at 12 months of age (43).”
From Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier (2015) · cites this paper as [43]
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“In addition, human presenilin-1 (PSEN-1) carrying the M146L/L286V mutations is expressed also under the control of the murine Thy-1 promoter (Oakley et al., 2006).”
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“5XFAD mice used in the current study were backcrossed for more than eight generations to C57Bl/6J wildtype mice (Jackson Laboratories, Bar Harbor, ME, USA) to obtain an incipient congenic line on a C57Bl/6J genetic background (Jawhar et al., 2010).”
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Self-citationNeuronal Clearance of Amyloid-β by Endocytic Receptor LRP1
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Replication of CLU, CR1, and PICALM Associations With Alzheimer Disease
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Self-citationKostylev, M. A., Kaufman, A. C., Nygaard, H. B., Patel, P., Haas, L. T., Gunther, E. C., Vortmeyer, A., & Strittmatter, S. M. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.643577 · Cited by 133
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Hüttenrauch, M., Brauß, A., Kurdakova, A., Borgers, H., Klinker, F., Liebetanz, D., Salinas-Riester, G., Wiltfang, J., Klafki, H. W., & Wirths, O. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.65 · Cited by 78
Self-citationPandey, R. S., Graham, L., Uyar, A., Preuss, C., Howell, G. R., & Carter, G. W. (2019) · Molecular Neurodegeneration · doi:10.1186/s13024-019-0351-3 · Cited by 37
Valencia-Olvera, A. C., Balu, D., Faulk, N., Amiridis, A., Wang, Y., Pham, C., Avila-Munoz, E., York, J. M., Thatcher, G. R. J., & LaDu, M. J. (2023) · Neurotherapeutics · doi:10.1007/s13311-023-01375-3 · Cited by 22
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Self-citation
Metadata
- Authors
- Bouter, Y., Kacprowski, T., Weissmann, R., Dietrich, K., Borgers, H., Brauß, A., Sperling, C., Wirths, O., Albrecht, M., Jensen, L. R., Kuss, A. W., & Bayer, T. A.
- Venue
- Frontiers in Aging Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2014-04-16
- Volume
- 6
- ISSN
- 1663-4365
- PMC
- PMC3997018
- Cited by
- 76
- References
- 20
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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