Alzheimer’s disease and hippocampal adult neurogenesis; exploring shared mechanisms

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The Neuroendocrinology of Stress: A Never Ending Story

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The ageing systemic milieu negatively regulates neurogenesis and cognitive function

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Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

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Wnt signalling regulates adult hippocampal neurogenesis

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Neurogenesis in the adult hippocampus

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Increased hippocampal neurogenesis in Alzheimer's disease

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Neurogenesis in the striatum of the adult human brain

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The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

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Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

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Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain

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VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

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Age-related memory deficits linked to circuit-specific disruptions in the hippocampus

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When neurogenesis encounters aging and disease

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Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease

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Presenilin: Running with Scissors in the Membrane

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A Critical Function for β-Amyloid Precursor Protein in Neuronal Migration Revealed by <i>In Utero</i> RNA Interference

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Notch in the Vertebrate Nervous System: An Old Dog with New Tricks

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Discovery of a Proneurogenic, Neuroprotective Chemical

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Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults

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GABA-cAMP Response Element-Binding Protein Signaling Regulates Maturation and Survival of Newly Generated Neurons in the Adult Hippocampus

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Neurogenesis and Alzheimer's disease: At the crossroads

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Impaired neurogenesis is an early event in the etiology of familial Alzheimer’s disease in transgenic mice

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Hippocampal neurogenesis: Learning to remember

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A new perspective on the role of the CREB family of transcription factors in memory consolidation via adult hippocampal neurogenesis

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Associative Learning Elicits the Formation of Multiple-Synapse Boutons

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Presenilin-1 Knockin Mice Reveal Loss-of-Function Mechanism for Familial Alzheimer’s Disease

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Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis

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Stabilized β-Catenin Functions through TCF/LEF Proteins and the Notch/RBP-Jκ Complex To Promote Proliferation and Suppress Differentiation of Neural Precursor Cells

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Testing the white matter retrogenesis hypothesis of cognitive aging

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CREB in adult neurogenesis – master and partner in the development of adult‐born neurons?

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Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum

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Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging

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Small-molecule activation of neuronal cell fate

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Perturbed Neurogenesis in the Adult Hippocampus Associated with Presenilin-1 A246E Mutation

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Signaling in adult neurogenesis: from stem cell niche to neuronal networks

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Molecular Mechanisms of Environmental Enrichment: Impairments in Akt/GSK3β, Neurotrophin-3 and CREB Signaling

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Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease

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Evidence of Aβ‐ and transgene‐dependent defects in ERK‐CREB signaling in Alzheimer’s models

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Functional γ-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and γ-secretase substrates

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DMH1, a Highly Selective Small Molecule BMP Inhibitor Promotes Neurogenesis of hiPSCs: Comparison of PAX6 and SOX1 Expression during Neural Induction

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Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin

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Small molecule GSK-3 inhibitors increase neurogenesis of human neural progenitor cells

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Essential role of tau phosphorylation in adult hippocampal neurogenesis

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CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis

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Neurogenesis in mouse models of Alzheimer's disease

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Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

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A small molecule p75NTR ligand protects neurogenesis after traumatic brain injury

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Tau Protein and Adult Hippocampal Neurogenesis

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All in the Family: How the APPs Regulate Neurogenesis

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High-throughput Screening in Embryonic Stem Cell-derived Neurons Identifies Potentiators of α-Amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type Glutamate Receptors

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Genetic Activation of ERK5 MAP Kinase Enhances Adult Neurogenesis and Extends Hippocampus-Dependent Long-Term Memory

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Of mice and men: neurogenesis, cognition and Alzheimer’s disease

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Magnesium Elevation Promotes Neuronal Differentiation While Suppressing Glial Differentiation of Primary Cultured Adult Mouse Neural Progenitor Cells through ERK/CREB Activation

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Hippocampal expression of cell‐adhesion glycoprotein neuroplastin is altered in Alzheimer's disease

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Alterations of hippocampal neurogenesis during development of Alzheimer's disease-like pathology in OXYS rats

Rudnitskaya, E. A., Kozlova, T. A., Burnyasheva, A. O., Kolosova, N. G., & Stefanova, N. A. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.11.008 · Cited by 26 · see citing works

GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice

Liu, F., Tian, N., Zhang, H., Li, S., Zhou, Q., Yang, Y., Zheng, J., & Wang, J. (2020) · Theranostics · doi:10.7150/thno.43829 · Cited by 26 · see citing works

Alzheimer's Disease and Its Potential Alternative Therapeutics.

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A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study

Vauzour, D., Scholey, A. B., White, D., Cohen, N. J., Cassidy, A., Gillings, R., Irvine, M. A., Kay, C. D., Kim, M. G., King, R., et al. (2023) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2023.06.008 · Cited by 24 · see citing works

Therapeutic Strategies Aimed at Improving Neuroplasticity in Alzheimer Disease

Colavitta, M. F., & Barrantes, F. J. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15082052 · Cited by 25 · see citing works

Exercising New Neurons to Vanquish Alzheimer Disease

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Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain

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Histamine H3 Receptor Antagonist Enhances Neurogenesis and Improves Chronic Cerebral Hypoperfusion-Induced Cognitive Impairments

Wang, N., Ma, J., Liu, J., Wang, J., Liu, C., Wang, H., Liu, Y. U., Yan, H., & Jiang, S. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01583 · Cited by 23 · see citing works

Neuroplasticity, limbic neuroblastosis and neuro-regenerative disorders

Kandasamy, M., & Aigner, L. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.235214 · Cited by 23 · see citing works

Notch Signalling in the Hippocampus of Patients With Motor Neuron Disease

Gómez‐Pinedo, U., Galán, L., Matías‐Guiu, J. A., et al. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00302 · Cited by 23 · see citing works

Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanisms

Kakkar, A., Singh, H., Singh, B. K., Kumar, A., Mishra, A. K., & Chopra, H. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251374353 · Cited by 23 · see citing works

Endurance exercise-induced expression of autophagy-related protein coincides with anabolic expression and neurogenesis in the hippocampus of the mouse brain

Jang, Y. (2020) · Neuroreport · doi:10.1097/wnr.0000000000001431 · Cited by 22 · see citing works

Epigenetic Regulation of Neural Stem Cells: The Emerging Role of Nucleoporins

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Structure–activity relationships of sulfonamides derived from carvacrol and their potential for the treatment of Alzheimer's disease

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Untold New Beginnings: Adult Hippocampal Neurogenesis and Alzheimer’s Disease

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Deep brain stimulation and cognition: Translational aspects

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Chlorzoxazone exhibits neuroprotection against Alzheimer’s disease by attenuating neuroinflammation and neurodegeneration in vitro and in vivo

Bai, Y., & Ma, X. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106790 · Cited by 21 · see citing works

Multiple Roles for Cholinergic Signaling from the Perspective of Stem Cell Function

Takahashi, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020666 · Cited by 19 · see citing works

Selective vulnerabilities and biomarkers in neurocognitive aging

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Memory-related process in physiological status and alzheimer’s disease

Fotuhi, S. N., Khalaj‐Kondori, M., Feizi, M. A. H., & Talebi, M. (2020) · Molecular Biology Reports · doi:10.1007/s11033-020-05438-y · Cited by 18 · see citing works

“Till Death Do Us Part”: A Potential Irreversible Link Between Aberrant Cell Cycle Control and Neurodegeneration in the Adult Olfactory Bulb

Omais, S., Jaafar, C., & Ghanem, N. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00144 · Cited by 19 · see citing works

Effects of Cyperus rotundus Extract on Spatial Memory Impairment and Neuronal Differentiation in Rat Model of Alzheimer's Disease

Shakerin, Z., Esfandiari, E., Razavi, S., Alaei, H., Ghanadian, M., & Dashti, G. (2020) · Advanced Biomedical Research · doi:10.4103/abr.abr_173_19 · Cited by 19 · see citing works

Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9 transgenic mice: Effect of long-term treatment with paroxetine

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Thyroid hormone treatment alleviates the impairments of neurogenesis, mitochondrial biogenesis and memory performance induced by methamphetamine

Tamijani, S. M. S., Beirami, E., Ahmadiani, A., & Dargahi, L. (2019) · NeuroToxicology · doi:10.1016/j.neuro.2019.05.003 · Cited by 17 · see citing works

Hippocampal Subfield Volumes in Middle-Aged Adults at Risk of Dementia

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High-content analysis and Kinetic Image Cytometry identify toxicity and epigenetic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells

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Effects of Aerobic Training on Brain Plasticity in Patients with Mild Cognitive Impairment: A Systematic Review of Randomized Controlled Trials

Farhani, F., Shahrbanian, S., Auais, M. A., Hekmatikar, A. H. A., & Suzuki, K. (2022) · Brain Sciences · doi:10.3390/brainsci12060732 · Cited by 17 · see citing works

Neural Stem Cell Dysfunction in Human Brain Disorders

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Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model

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Restoration of mitochondrial homeostasis by Wnt3a/β-catenin/c-Myc alleviates cadmium-induced neural stem cell senescence and cognitive impairment in mouse hippocampus

Zhang, Y., Gu, Q., Li, Y., Li, J., Han, Y., Feng, L., Qin, X., Zhang, J., Zhou, Z., & Chang, X. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.138972 · Cited by 14 · see citing works

Naproxen as a potential candidate for promoting rivastigmine anti-Alzheimer activity against aluminum chloride-prompted Alzheimer's-like disease in rats; neurogenesis and apoptosis modulation as a possible underlying mechanism

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The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease

Früholz, I., & Meyer‐Luehmann, M. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1456253 · Cited by 15 · see citing works

Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway

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From Light to Sound: Photoacoustic and Ultrasound Imaging in Fundamental Research of Alzheimer’s Disease

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Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis

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Differential neurogenesis in the adult rat dentate gyrus: an identifiable zone that consistently lacks neurogenesis

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190. Neurogenesis Inhibits Stress-Responsive Cells in the Ventral Dentate Gyrus

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Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice

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A combination of running and memantine increases neurogenesis and reduces activation of developmentally-born dentate granule neurons in rats

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