Cited by 3,475Functional Brain Connectivity StudiesAdvanced MRI Techniques and ApplicationsAdvanced Neuroimaging Techniques and Applications

DPARSF: a MATLAB toolbox for “pipeline” data analysis of resting-state fMRI

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Yan·2010·Frontiers in System Neuroscience

Abstract

Resting-state functional magnetic resonance imaging (fMRI) has attracted more and more attention because of its effectiveness, simplicity and non-invasiveness in exploration of the intrinsic functional architecture of the human brain. However, user-friendly toolbox for "pipeline" data analysis of resting-state fMRI is still lacking. Based on some functions in Statistical Parametric Mapping (SPM) and Resting-State fMRI Data Analysis Toolkit (REST), we have developed a MATLAB toolbox called Data Processing Assistant for Resting-State fMRI (DPARSF) for "pipeline" data analysis of resting-state fMRI. After the user arranges the Digital Imaging and Communications in Medicine (DICOM) files and click a few buttons to set parameters, DPARSF will then give all the preprocessed (slice timing, realign, normalize, smooth) data and results for functional connectivity, regional homogeneity, amplitude of low-frequency fluctuation (ALFF), and fractional ALFF. DPARSF can also create a report for excluding subjects with excessive head motion and generate a set of pictures for easily checking the effect of normalization. In addition, users can also use DPARSF to extract time courses from regions of interest.

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Authors
Yan
Venue
Frontiers in System Neuroscience
Published
2010
Volume
4
Pages
13-13
ISSN
1662-5137 (ISSN-L)
OpenAlex
W2057550180
Cited by
3,475
References
51
Citations by year
2026: 78 · 2025: 227 · 2024: 250 · 2023: 268 · 2022: 333 · 2021: 300 · 2020: 296 · 2019: 289 · 2018: 269 · 2017: 320 · 2016: 277 · 2015: 256 · 2014: 151 · 2013: 86 · 2012: 50
FWCI
30.02
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Systems Neuroscience (publishedVersion, cc-by)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Natural Science Foundation of China (30621130074, 30770594)
  • Beijing Normal University
  • Program for Changjiang Scholars and Innovative Research Team in University
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
Keywords
resting-state fMRI, MATLAB toolbox, functional connectivity, regional homogeneity, amplitude of low-frequency fluctuation, fractional ALFF, image preprocessing, SPM

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