Polyamines and gut microbiota
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The microbiota of gut is the community of microbes living in an individual's gastrointestinal tract. Several bacterial genera and species act in a concerted manner to establish metabolic interactions with the host (1). Although there is a general high interest in the study of metabolite flow across the microbe-host, at present, only some studies are targeting specific metabolites produced by intestinal microbiota such as polyamines (PAs)
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Polyamines exhibit numerous beneficial effects including increased longevity, recovery of injured mucosa, and favorable effects on cognitive function.
“Polyamines exhibit numerous beneficial effects including increased longevity, recovery of injured mucosa, as well as favorable effects on cognitive function.122, 123, 124”
From Regulation of Intestinal Barrier Function by Microbial Metabolites (2021) · cites this paper as [122]
Gut microbes such as E. coli, Bacteroides spp. and Fusobacterium spp. can synthesize polyamines.
“Gut microbes such as E. coli, Bacteroides spp. and Fusobacterium spp. can synthesize polyamines.122”
From Regulation of Intestinal Barrier Function by Microbial Metabolites (2021) · cites this paper as [122]
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- Authors
- Tofalo, R., Cocchi, S., & Suzzi, G.
- Affiliations
- University of Teramo (IT)
- Corresponding author
- Tofalo, Rosanna
- ORCID
- Tofalo, Rosanna
- Venue
- Frontiers in Nutrition
- Publisher
- Frontiers Media SA
- Published
- 2019-02-25
- Volume
- 6
- Pages
- 16-16
- ISSN
- 2296-861X (ISSN-L)
- PMC
- PMC6397830
- OpenAlex
- W2917494464
- Cited by
- 306
- References
- 58
- Citations by year
- 2026: 48 · 2025: 41 · 2024: 42 · 2023: 41 · 2022: 34 · 2021: 59 · 2020: 30 · 2019: 10 · 2018: 1
- FWCI
- 11.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Nutrition (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- UniTERAMO Research Catalog (University of Teramo) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Keywords
- polyamines, gut microbiota, host-microbe metabolic interactions, microbial metabolites, polyamine metabolism
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