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Cited by 519Antioxidant Activity and Oxidative StressPhytochemicals and Antioxidant ActivitiesExercise and Physiological Responses

Carotenoids and Chlorophylls as Antioxidants

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Pérez-Gálvez, Antonio, Viera, Isabel, Roca, María·2020·Antioxidants
DOI 10.3390/antiox9060505PMC PMC7346216
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Abstract

Chlorophylls and carotenoids are natural pigments that are present in our daily diet, especially with the increasing tendency towards more natural and healthy behaviors among consumers. As disturbed antioxidant homeostasis capacities seem to be implicated in the progress of different pathologies, the antioxidant properties of both groups of lipophilic compounds have been studied. The objective of this review was to analyze the state-of-the-art advances in this field. We conducted a systematic bibliographic search (Web of Science™ and Scopus®), followed by a comprehensive and critical description of the results, with special emphasis on highly cited and more recently published research. In addition to an evaluative description of the methodologies, this review discussed different approaches used to obtain a physiological perspective, from in vitro studies to in vivo assays using oxidative biomarkers. From a chemical viewpoint, many studies have demonstrated how a pigment’s structure influences its antioxidant response and the underlying mechanisms. The major outcome is that this knowledge is essential for interpreting new data in a metabolic networks context in the search for more direct applications to health. A promising era is coming where the term “antioxidant” is understood in terms of its broadest significance.

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Cited by

Sorted by citations

Authors
Pérez-Gálvez, A., Viera, I., & Roca, M.
Affiliations
  • Food Phytochemistry Department, Instituto de la Grasa (CSIC), University Campus, Building 46, 41013 Sevilla, Spain
  • Consejo Superior de Investigaciones Científicas (ES)
Corresponding author
Roca, María
ORCID
Venue
Antioxidants
Publisher
MDPI AG
Published
2020-06-09
Volume
9
Issue
6
Pages
505
ISSN
2076-3921 (ISSN-L)
DOI
10.3390/antiox9060505
PMC
PMC7346216
OpenAlex
W3034813253
Cited by
519
References
8
Citations by year
2026: 88 · 2025: 125 · 2024: 95 · 2023: 76 · 2022: 84 · 2021: 46 · 2020: 5
FWCI
4.61
Type
journal article
Language
en
Open access
Licence
Locations
  • Antioxidants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Ministerio de Ciencia, Investigación y Universidades (RTI2018-095415-B-I00, AGL2017-87884-R)
Topics
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
carotenoids, chlorophyll, antioxidant activity, natural pigments, dietary antioxidants, oxidative stress, oxidative stress biomarkers, structure-activity relationship, lipid peroxidation, health-promoting compounds

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