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Preparation and In Vitro Analysis of Microcapsule Thalidomide Formulation for Targeted Suppression of TNF-α

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The alkyl side chain of PACA nanoparticles dictates the impact on cellular stress responses and the mode of particle-induced cell deathPreprint

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Polyphenols and Their Impact on the Prevention of Neurodegenerative Diseases and Development

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The Hitchhiker’s Guide to Human Therapeutic Nanoparticle Development

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Gold Nanoparticles in Neurological Diseases: A Review of Neuroprotection

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The blood–brain barrier: a help and a hindrance

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Brain drug delivery and neurodegenerative diseases: Polymeric PLGA-based nanoparticles as a forefront platform

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Role of pro-inflammatory cytokines in Alzheimer’s disease and neuroprotective effects of pegylated self-assembled nanoscaffolds

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Dense poly(ethylene glycol) coatings maximize nanoparticle transport across lymphatic endothelial cells and accumulate in the skindraining lymph nodes

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Emerging strategies to fabricate polymeric nanocarriers for enhanced drug delivery across blood-brain barrier: An overview

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Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery

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Development of ionic liquid-coated PLGA nanoparticles for applications in intravenous drug delivery

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PLGA-Based Curcumin Delivery System: An Interesting Therapeutic Approach in the Treatment of Alzheimer's Disease

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PLGA/PEG Nanoparticles Loaded with Cyclodextrin-Peganum harmala Alkaloid Complex and Ascorbic Acid with Promising Antimicrobial Activities

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Synthesis, characterization, and biological evaluation of some novel Schiff bases as potential metabolic enzyme inhibitors

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Surface Bio‐engineered Polymeric Nanoparticles

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Brain-targeted Tet-1 peptide-PLGA nanoparticles for berberine delivery against STZ-induced Alzheimer’s disease in a rat model: Alleviation of hippocampal synaptic dysfunction, Tau pathology, and amyloidogenesis

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Ferulic acid-loaded polymeric nanoparticles prepared from nano-emulsion templates facilitate internalisation across the blood–brain barrier in model membranes

Garcia, L., Palma-Florez, S., Espinosa, V., Rokni, F. S., Lagunas, A., Mir, M., García, M. J. N., Samitier, J., Rodríguez‐Abreu, C., & Grijalvo, S. (2023) · Nanoscale · doi:10.1039/d2nr07256d · Cited by 41 · see citing works

Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model

Madani, F., Morovvati, H., Webster, T. J., Asaadi, S. N., Rezayat, S. M., Hadjighassem, M., Khosravani, M., & Adabi, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-69888-1 · Cited by 38 · see citing works

Paclitaxel Delivery to the Brain for Glioblastoma Treatment

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Nanomedicine in Clinical Photodynamic Therapy for the Treatment of Brain Tumors

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Multifunctional Nanocarriers for Alzheimer’s Disease: Befriending the Barriers

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Revamping Parkinson’s disease therapy using PLGA-based drug delivery systems

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Nanomedicine in the treatment of Alzheimer’s disease: bypassing the blood-brain barrier with cutting-edge nanotechnology

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Harnessing nanomedicine for modulating microglial states in the central nervous system disorders: Challenges and opportunities

Li, H., Guan, M., Zhang, N.-N., Wang, Y., Liang, T., Wu, H., Wang, C., Sun, T., & Liu, S. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117011 · Cited by 16 · see citing works

Surface-functionalized nanoparticles for targeted drug delivery across the blood-brain barrier: advances and challenges in neurodegenerative disease therapy

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Advancements in nose-to-brain drug targeting for Alzheimer’s disease: a review of nanocarriers and clinical insights

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The nanocarrier strategy for crossing the blood-brain barrier in glioma therapy

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Aurothioglucose encapsulated nanoparticles fostered neuroprotection in streptozotocin-induced Alzheimer’s disease

Kushawaha, S. K., Ashawat, M. S., Soni, D., Kumar, P., Rimpi, & Baldi, A. (2024) · Brain Research · doi:10.1016/j.brainres.2024.148906 · Cited by 11 · see citing works

Functionalized Nanoparticles: A Promising Approach for Effective Management of Alzheimer’s Disease

Bogadi, S., Bhaskaran, M., Ravichandran, V., Nesamony, J., Selvam, C., Kuppusamy, G., Prakash, G., Karri, V. V. S. R., Mallick, S., Farahim, F., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04917-2 · Cited by 10 · see citing works

Nanomedicine strategies for central nervous system (CNS) diseases

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Epigenetic Alterations in Alzheimer’s Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems

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Biochemical investigation and in silico analysis of the therapeutic efficacy of Ipriflavone through Tet-1 Surface-Modified-PLGA nanoparticles in Streptozotocin-Induced Alzheimer’s like Disease: Reduced oxidative damage and etiological Descriptors

Saleh, S. R., Khamiss, S. E., Madhy, S. A., Khattab, S. N., Sheta, E., Elnozahy, F. Y., Thabet, E. H., Ghareeb, D. A., Awad, D., & El-Bessoumy, A. A. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.125021 · Cited by 8 · see citing works

Improved cognition and memory via PLGA nanoparticle-mediated delivery of curcumin and piperine in an in vivo Alzheimer’s disease model

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New insights of miRNA molecular mechanisms in breast cancer brain metastasis and therapeutic targets

Hussen, B. M., Abdullah, K. H., Abdullah, S. R., majeed, N. M., Mohamadtahr, S., Rasul, M. F., Dong, P., Taheri, M. N., & Samsami, M. (2023) · Non-coding RNA Research · doi:10.1016/j.ncrna.2023.09.003 · Cited by 8 · see citing works

Biodegradable nanoplatforms for antigen delivery: part I – state of the art review of polymeric nanoparticles for cancer immunotherapy

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Advances in alginate-based nanoformulations: Innovative and effective strategies for targeting and treating brain disorders

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PLGA mediated drug delivery for Alzheimer's disease

Pandya, T., Kulkarni, M., Acharya, S. P., & Prajapati, B. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13205-6.00024-8 · Cited by 5 · see citing works

Nanoparticle Formulations for the Improvement of Symptomatic Treatments of Neurodegenerative Disorders

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Emerging Roles of polymeric nanoparticles in cancer Therapy: Design, Targeting, and clinical integration

Sheykholeslami, S. E., Halimi, S., Ahangari, F., Mohammadgholi, A., Mansouri, A., Dehaghi, H. M., Eynakchi, M. K., Hosseini, S., Tahouri, S. K. S., Shahbazi, Z., et al. (2025) · European Polymer Journal · doi:10.1016/j.eurpolymj.2025.114447 · Cited by 4 · see citing works

Overcoming the blood–brain barrier in Alzheimer's disease: translational perspectives on advanced drug delivery platforms

Roamcharern, N., & Yubolphan, R. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1810486 · Cited by 4 · see citing works

Fabrication of epidermal growth factor functionalized polymeric poly(lactic-co-glycolic acid) nanoparticles loaded SN-38 and perfluorocarbon for treatment and care: investigation of antiproliferative effects and apoptosis in cervical cancer cells

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Nano-formulated curcumin uptake and biodistribution in the fetal growth restricted newborn piglet brain

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Synthesis and characterization of chemical engineered PLGA nanosphere: Triggering mechanism of Catechol-O-methyltransferase inhibition on in vivo neurodegeneration

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Rivastigmine Loaded PEG-PLGA Nanoparticles for Enhanced Delivery to the Brain: In-Vitro and In-Vivo Studies for Alzheimer’s diseasePreprint

Prakash, J., Prakash, P., Prasad, V. V., Pushpanathan, A. C. S., Somasundaram, & ShanmugaRajan (2022) · Research Square · doi:10.21203/rs.3.rs-1433109/v1 · Cited by 3 · see citing works

Advances in Strategies to Transport Nanoparticles Across the Blood–Brain Barrier for Drug Delivery into the Brain for the Treatment of Alzheimer’s Disease

Silva, R., Monteiro, J., Ramalho, M. J., Andrade, S., Loureiro, J. A., & Pereira, M. C. (2026) · Pharmaceuticals · doi:10.3390/ph19050685 · Cited by 2 · see citing works

Surface engineered nano architectonics: An evolving paradigm for tackling Alzheimer's disease

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Engineering Polymers: From Biodegradable Platforms to Intelligent Drug Carriers

Kaur, M. J., Aher, V. D., Bujji, S., Chaudhari, H. C., Mohammed, I. A., Bhise, M. R., Tiwari, G., & Sharma, P. (2025) · Polymer-Plastics Technology and Materials · doi:10.1080/25740881.2025.2487888 · Cited by 2 · see citing works

Evaluation of the neuroprotective potential of optimized intranasal polydopamine nanoparticles in a lipopolysaccharide-induced rat model for Alzheimer’s disease management

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Possibilities and challenges of next-generation therapeutics: solid lipid nanoparticles revolutionizing metabolic disorder treatment

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POLYMERIC SILVER NANOCARRIERS: INNOVATIVE DRUG DELIVERY STRATEGIES FOR ALZHEIMER’S DISEASE AND NEURODEGENERATIVE DISORDERS

KINKAR, H., DHARPURE, D., & Tumme, D. M. (2026) · International Journal of Current Pharmaceutical Research · doi:10.22159/ijcpr.2026v18i2.8049 · Cited by 1 · see citing works

Neuropeptides in the Management of Alzheimer’s Disease: From Pathophysiology to Therapeutic Opportunities

Tiwari, S., Yadav, S. K., Kumari, M., Dhakal, T., & Puranik, N. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27073206 · Cited by 1 · see citing works

Formulation and characterization of CMPI nanoparticles for enhanced targeting of brain nicotinic receptors by positive allosteric modulator

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Recent Trends in Nano-Drug Delivery Systems in the Treatment for Alzheimer ’s Disease

Mejias, S., Sneed, K. B., & Pathak, Y. V. (2025) · Nanotechnology & Applications · doi:10.33425/2639-9466.1037 · Cited by 1 · see citing works

Nanobiomaterials Revolutionizing Biomedical Science: Special Issue—“Nanotechnology for Biomedical Applications”

Sardo, C. (2023) · Applied Sciences · doi:10.3390/app13106123 · Cited by 1 · see citing works

Biofate and cellular interactions of PLGA nanoparticles

Macedo, L. B., Codevilla, C. F., Mathes, D., Maia-do-Amaral, B. C., Rolim, C. M. B., & Nogueira-Librelotto, D. R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91215-0.00003-0

Advancements in the diagnosis of Alzheimer’s disease (AD) through biomarker detection

Jogdand, A. H., Rice, O., & Chen, Y. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95439-6.00017-x

Polymeric Nanomaterials for Drug Delivery to the Brain

Jogdeo, C. M., Islam, F. S., Siddhanta, K., & Oupický, D. (2024) · Springer eBooks · doi:10.1007/978-3-031-68237-7_48

Introductory Chapter: Redefining the Therapeutic Landscape of the Smart Drug Delivery System

Shukla, R., & Saraf, S. A. (2025) · Pharmaceutical science. · doi:10.5772/intechopen.1009965

Mechanisms in Crossing the Blood-brain Barrier Using PLGA Nanoparticles

Kavandal, P., Lilova, K. I., & Kethar, J. (2024) · Journal of Student Research · doi:10.47611/jsrhs.v13i3.7411

Functionalized silica nanocarriers for brain-targeted delivery

Mathure, D. M., Salunke, M. R., Phadtare, P., & Walle, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24802-3.00015-9

Natural Product Assembly in Nanoformulation: Importance in Neurodegenerative Diseases

Verma, K., Singh, R., Jain, S., & Sharma, S. (2026) · Springer eBooks · doi:10.1007/978-981-95-5088-3_6

Breaking the Blood-Brain Barrier: Nanotechnology's Role in Treating Neurodegenerative Diseases

Sowmyasree, C. D., Joshi, V., & Sunkanna, V. K. (2026) · Micro and Nanosystems · doi:10.2174/0118764029359991251204222805

Molecular dynamics simulation of 2-aminothiazoline-4-carboxylic acid, a biomarker for cyanide, linked to ionotropic glutamate receptors to reveal neurotoxicity pathwaysPreprint

Khan, H. M. A., Yusof, N. A., Ahmad, S. A. A., Yu, C. Y., Rahman, S. F. A., Raston, N. H. A., & Tejo, B. A. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6404005

Nanocarriers in Alzheimer’s Therapy: A Comprehensive Review on Nanoparticulate Drug Delivery Systems

Parashar, A. K., Saraogi, G. K., Sethi, V. A., & Yasin, H. K. A. (2026) · Current Neurovascular Research · doi:10.2174/0115672026435071260129105648

Nanotechnology-enabled targeting strategies for neurodegenerative disorders: role of functionalized nanoparticles

Vishwakarma, H., Chauhan, A., Kaur, L., & Awasthi, A. (2026) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgag060

Bridging the Gap: Harnessing Phytochemical-Loaded Nanocarriers for Enhanced Epilepsy Treatment

Kazemi, M., Arab, F., Nasiri, A., Besharatiyan, F., & Jahani, R. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06147-6

Fungal Metabolites as Multi-Target Modulators of Alzheimer’s Disease: An Integrated In Silico Docking and Molecular Dynamics Approach

Vijayan, D., Siva, K., Ramachandran, J., & Saravanan, D. (2026) · Malaysian Applied Biology · doi:10.55230/mabjournal.v55i3.3751

From gut microbiome to aging brain: Butyrate as a neurogeroscience effector

Mitrea, L., Calinoiu, L.-F., Martau, G.-A., Teleky, B.-E., Cocean, A.-M., Odocheanu, R., Stefanescu, B.-E., & Vodnar, D.-C. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.107037

PLGA mediated drug delivery for Alzheimer's disease

Pandya, T., Kulkarni, M., Acharya, S. P., & Prajapati, B. G. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13205-6.00024-8 · Cited by 5 · see citing works

Targeted nanoparticles for drug delivery through the blood–brain barrier for Alzheimer's disease

Roney, C. A., Kulkarni, P. V., Arora, V., Antich, P. P., Bonte, F. J., Wu, A., Mallikarjuana, N. N., Manohar, S. K., Liang, H., Kulkarni, A. R., et al. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.07.024 · Cited by 408 · see citing works

Nanoparticles as a vehicle for a novel neuroprotective drug to fight Alzheimer´s disease

Pasa, M. (2023) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/xa8p-g662

Recent Advances in Nanoparticle-Based Drug Delivery Strategies to Cross the Blood–Brain Barrier in Targeted Treatment of Alzheimer’s Disease

Le, H. T. N., Giang, V. T. T., Abioye, A. O., & Adejare, A. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18020192 · Cited by 8 · see citing works

Overcoming the blood–brain barrier in Alzheimer's disease: translational perspectives on advanced drug delivery platforms

Roamcharern, N., & Yubolphan, R. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1810486 · Cited by 4 · see citing works