Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

MANTOVANI, A., SOZZANI, S., LOCATI, M., ALLAVENA, P., & SICA, A. (2002) · Trends in Immunology · doi:10.1016/s1471-4906(02)02302-5 · Cited by 5,528 · see citing works

Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype

Munder, M., Eichmann, K., & Modolell, M. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.11.5347 · Cited by 647 · see citing works

Simultaneous Disruption of Interleukin (IL)-4 and IL-13 Defines Individual Roles in T Helper Cell Type 2–mediated Responses

McKenzie, G. J., Fallon, P. G., Emson, C. L., Grencis, R. K., & McKenzie, A. N. J. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.10.1565 · Cited by 354 · see citing works

Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity

Munder, M. (2005) · Blood · doi:10.1182/blood-2004-07-2521 · Cited by 335 · see citing works

IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype

Loke, P., Nair, M. G., Parkinson, J., Guiliano, D. B., Blaxter, M., & Allen, J. E. (2002) · BMC Immunology · doi:10.1186/1471-2172-3-7 · Cited by 322 · see citing works

Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation

Raes, G., Brys, L., Dahal, B. K., Brandt, J., Grooten, J., Brombacher, F., Vanham, G., Noël, W., Bogaert, P., Boonefaes, T., et al. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0304212 · Cited by 246 · see citing works

Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.

Mohrs, M., Ledermann, B., Köhler, G., Dorfmüller, A., Gessner, A., & Brombacher, F. (1999) · PubMed · Cited by 243 · see citing works

TH2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism

Welch, J. S., Escoubet‐Lozach, L., Sykes, D. B., Liddiard, K., Greaves, D. R., & Glass, C. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205873200 · Cited by 233 · see citing works

Differences Between IL-4- and IL-4 Receptor α-Deficient Mice in Chronic Leishmaniasis Reveal a Protective Role for IL-13 Receptor Signaling

Mohrs, M., Ledermann, B., Köhler, G., Dorfmüller, A., Gessner, A., & Brombacher, F. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.12.7302 · Cited by 221 · see citing works

Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-13

Scotton, C. J., Martínez, F. O., Smelt, M. J., Sironi, M., Locati, M., Mantovani, A., & Sozzani, S. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.2.834 · Cited by 138 · see citing works

Differential responses of human monocytes and macrophages to IL-4 and IL-13

Hart, P. H., Bonder, C. S., Balogh, J., Dickensheets, H. L., Donnelly, R. P., & Finlay‐Jones, J. J. (1999) · Journal of Leukocyte Biology · doi:10.1002/jlb.66.4.575 · Cited by 96 · see citing works

In Vitro Engagement of CD3 and CD28 Corrects T Cell Defects in Chronic Lymphocytic Leukemia

Bonyhadi, M. L., Frohlich, M. W., Rasmussen, A. L., Ferrand, C., Grosmaire, L. S., Robinet, É., Leis, J. F., Maziarz, R. T., Tiberghien, P., & BERENSON, R. J. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.4.2366 · Cited by 45 · see citing works

Progress and challenges in translating the biology of atherosclerosis

Libby, P., Ridker, P. M., & Hansson, G. K. (2011) · Nature · doi:10.1038/nature10146 · Cited by 4,010 · see citing works

Coordinated regulation of myeloid cells by tumours

Gabrilovich, D. I., Ostrand-Rosenberg, S., & Bronte, V. (2012) · Nature Reviews Immunology · doi:10.1038/nri3175 · Cited by 3,544 · see citing works

Macrophage activation and polarization

Martinez, F. O. (2008) · Frontiers in Bioscience · doi:10.2741/2692 · Cited by 3,160 · see citing works

Alternative Activation of Macrophages: An Immunologic Functional Perspective

Martinez, F. O., Helming, L., & Gordon, S. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132532 · Cited by 2,745 · see citing works

Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression

Martínez, F. O., Gordon, S., Locati, M., & Mantovani, A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.10.7303 · Cited by 2,336 · see citing works

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

Wang, N., Liang, H., & Zen, K. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00614 · Cited by 1,997 · see citing works

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

Rőszer, T. (2015) · Mediators of Inflammation · doi:10.1155/2015/816460 · Cited by 1,762 · see citing works

Neuroinflammation and M2 Microglia: The Good, the Bad, and the Inflamed

Cherry, J. D., Olschowka, J. A., & O’Banion, M. K. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-98 · Cited by 1,748 · see citing works

Repertoire of microglial and macrophage responses after spinal cord injury

David, S., & Kroner, A. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3053 · Cited by 1,437 · see citing works

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

Rath, M., ller, I. M. ⁄., Kropf, P., Closs, E. I., & Munder, M. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00532 · Cited by 1,271 · see citing works

Altered macrophage differentiation and immune dysfunction in tumor development

Sica, A., & Bronte, V. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31422 · Cited by 1,239 · see citing works

Macrophage Polarization in Inflammatory Diseases

Liu, Y., Zou, X., Chai, Y., & Yao, Y.-M. (2014) · International Journal of Biological Sciences · doi:10.7150/ijbs.8879 · Cited by 1,109 · see citing works

Metabolic Reprograming in Macrophage Polarization

Galván-Peña, S., & O’Neill, L. A. J. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00420 · Cited by 944 · see citing works

Microglia in the TBI brain: The good, the bad, and the dysregulated

Loane, D. J., & Kumar, A. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.08.018 · Cited by 816 · see citing works

Krüppel-like factor 4 regulates macrophage polarization

Liao, X., Sharma, N., Kapadia, F., Zhou, G., Lu, Y., Hong, H., Paruchuri, K., Mahabeleshwar, G. H., Dalmas, E., Venteclef, N., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45444 · Cited by 778 · see citing works

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

Dyken, S. J. V., & Locksley, R. M. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095906 · Cited by 714 · see citing works

Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans

Libby, P., Lichtman, A. H., & Hansson, G. K. (2013) · Immunity · doi:10.1016/j.immuni.2013.06.009 · Cited by 667 · see citing works

Macrophage phenotypes during tissue repair

Novak, M. L., & Koh, T. J. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.1012512 · Cited by 658 · see citing works

Alternatively activated microglia and macrophages in the central nervous system

Franco, R., & Fernández‐Suárez, D. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.05.003 · Cited by 650 · see citing works

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB

Porta, C., Rimoldi, M., Raes, G., Brys, L., Ghezzi, P., Di Liberto, D., Dieli, F., Ghisletti, S., Natoli, G., De Baetselier, P., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809784106 · Cited by 627 · see citing works

More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond Chemotaxis

Gschwandtner, M., Derler, R., & Midwood, K. S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02759 · Cited by 611 · see citing works

Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer

Yu, J., Du, W., Fang, Y., Wang, Y., Li, H., Cao, S., Yu, W., Shen, C., Liu, J., & Ren, X. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1201449 · Cited by 608 · see citing works

Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

Tarique, A. A., Logan, J., Thomas, E., Holt, P. G., Sly, P. D., & Fantino, E. (2015) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2015-0012oc · Cited by 583 · see citing works

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

Kadl, A., Meher, A. K., Sharma, P. R., Lee, M. Y., Doran, A. C., Johnstone, S. R., Elliott, M. R., Gruber, F., Han, J., Chen, W., et al. (2010) · Circulation Research · doi:10.1161/circresaha.109.215715 · Cited by 573 · see citing works

Obstacles and opportunities for understanding macrophage polarization

Murray, P. J., & Wynn, T. A. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0710409 · Cited by 558 · see citing works

Defining GM-CSF– and Macrophage-CSF–Dependent Macrophage Responses by In Vitro Models

Lacey, D. C., Achuthan, A. A., Fleetwood, A. J., Dinh, H., Roiniotis, J., Scholz, G. M., Chang, M. W., Beckman, S. K., Cook, A. D., & Hamilton, J. A. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103426 · Cited by 528 · see citing works

Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

Yurdagul, A., Subramanian, M., Wang, X., Crown, S. B., Ilkayeva, O. R., Darville, L., Kolluru, G. K., Rymond, C. C., Gerlach, B. D., Zheng, Z., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.01.001 · Cited by 525 · see citing works

Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin

Jaguin, M., Houlbert, N., Fardel, O., & Lecureur, V. (2013) · Cellular Immunology · doi:10.1016/j.cellimm.2013.01.010 · Cited by 520 · see citing works

Wound Macrophages as Key Regulators of Repair

Brancato, S. K., & Albina, J. E. (2011) · The American Journal of Pathology · doi:10.1016/j.ajpath.2010.08.003 · Cited by 508 · see citing works

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

Martínez, F. O., Helming, L., Milde, R., Varin, A., Melgert, B. N., Draijer, C., Thomas, B., Fabbri, M., Crawshaw, A., Ho, L., et al. (2013) · Blood · doi:10.1182/blood-2012-06-436212 · Cited by 495 · see citing works

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

Batista‐González, A., Vidal, R. M., Criollo, A., & Carreño, L. J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02993 · Cited by 435 · see citing works

Physical and mechanical regulation of macrophage phenotype and function

McWhorter, F. Y., Davis, C. T., & Liu, W. F. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1796-8 · Cited by 437 · see citing works

Myeloid Cell-Derived Arginase in Cancer Immune Response

Grzywa, T. M., Sosnowska, A., Matryba, P., Rydzyńska, Z., Jasiński, M., Nowis, D., & Gołąb, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00938 · Cited by 434 · see citing works

Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway

Dai, E., Han, L., Liu, J., Xie, Y., Zeh, H. J., Kang, R., Bai, L., & Tang, D. (2020) · Nature Communications · doi:10.1038/s41467-020-20154-8 · Cited by 428 · see citing works

Roles of microglia in brain development, tissue maintenance and repair

Michell‐Robinson, M. A., Touil, H., Healy, L. M., Owen, D. R., Durafourt, B. A., Bar‐Or, A., Antel, J. P., & Moore, C. S. (2015) · Brain · doi:10.1093/brain/awv066 · Cited by 421 · see citing works

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

Shaykhiev, R., Krause, A., Salit, J., Strulovici‐Barel, Y., Harvey, B., O’Connor, T. P., & Crystal, R. G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900473 · Cited by 402 · see citing works

Folate Receptor β Is Expressed by Tumor-Associated Macrophages and Constitutes a Marker for M2 Anti-inflammatory/Regulatory Macrophages

Puig‐Kröger, A., Sierra‐Filardi, E., Domínguez‐Soto, Á., Samaniego, R., Corcuera, M. T., Gómez, F., Ratnam, M., Sánchez‐Mateos, P., & Corbí, A. L. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2050 · Cited by 389 · see citing works

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

Bourlier, V., Zakaroff‐Girard, A., Miranville, A., Barros, S. D., Maumus, M., Sengenès, C., Galitzky, J., Lafontan, M., Karpe, F., Frayn, K. N., et al. (2008) · Circulation · doi:10.1161/circulationaha.107.724096 · Cited by 373 · see citing works

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies

Martin, K. E., & Garcı́a, A. J. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.03.038 · Cited by 375 · see citing works

Classical and alternative activation of mononuclear phagocytes: Picking the best of both worlds for tumor promotion

Ginderachter, J. A. V., Movahedi, K., Ghassabeh, G. H., Meerschaut, S., Beschin, A., Raes, G., & BAETSELIER, P. D. (2006) · Immunobiology · doi:10.1016/j.imbio.2006.06.002 · Cited by 370 · see citing works

Macrophage: A Potential Target on Cartilage Regeneration

Fernandes, T. L., Gomoll, A. H., Lattermann, C. M., Hernandez, A. J., Bueno, D. F., & Amano, M. T. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00111 · Cited by 354 · see citing works

Phenotypic Transitions of Macrophages Orchestrate Tissue Repair

Novak, M. L., & Koh, T. J. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.06.034 · Cited by 355 · see citing works

Immunomodulatory Biomaterials for Tissue Repair

Whitaker, R. C., Hernaez‐Estrada, B., Hernández, R. M., Santos‐Vizcaíno, E., & Spiller, K. L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00895 · Cited by 345 · see citing works

The Role of Macrophage Polarization in Infectious and Inflammatory Diseases

Labonte, A. C., Tosello‐Trampont, A., & Hahn, Y. S. (2014) · Molecules and Cells · doi:10.14348/molcells.2014.2374 · Cited by 335 · see citing works

In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

Hunter, M. M., Wang, A., Parhar, K. K. S., Johnston, M. J. G., van Rooijen, N., Beck, P. L., & McKay, D. M. (2010) · Gastroenterology · doi:10.1053/j.gastro.2009.12.041 · Cited by 310 · see citing works

Macrophage-based therapeutic strategies in regenerative medicine

Spiller, K. L., & Koh, T. J. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.05.010 · Cited by 308 · see citing works

Adipose tissue macrophages

Zeyda, M., & Stulnig, T. M. (2007) · Immunology Letters · doi:10.1016/j.imlet.2007.07.003 · Cited by 307 · see citing works

Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry

Huang, Y., Wang, M., Yu, S. Y., Costanzo, N. D., Mitchell, C., Achuthan, A. A., Hamilton, J. A., Busuttil, R. A., & Boussioutas, A. (2019) · Nature Communications · doi:10.1038/s41467-019-11788-4 · Cited by 301 · see citing works

Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases

Bussink, A. P., Speijer, D., Aerts, J., & Boot, R. (2007) · Genetics · doi:10.1534/genetics.107.075846 · Cited by 301 · see citing works

When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma

Roesch, S., Rapp, C., Dettling, S., & Herold‐Mende, C. C. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020436 · Cited by 293 · see citing works

Nanobody-Based Targeting of the Macrophage Mannose Receptor for Effective In Vivo Imaging of Tumor-Associated Macrophages

Movahedi, K., Schoonooghe, S., Laoui, D., Houbracken, I., Waelput, W., Breckpot, K., Bouwens, L., Lahoutte, T., BAETSELIER, P. D., Raes, G., et al. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-2994 · Cited by 292 · see citing works

Alternatively activated macrophages; a double-edged sword in allergic asthma

Abdelaziz, M. H., Abdelwahab, S. F., Wan, J., Cai, W., Wang, H., Cheng, J., Kesavan, D. K., Vasudevan, A., Sadek, A., Su, Z., et al. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02251-w · Cited by 283 · see citing works

Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1

Raggi, F., Pelassa, S., Pierobon, D., Penco, F., Gattorno, M., Novelli, F., Eva, A., Varesio, L., Giovarelli, M., & Bosco, M. C. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01097 · Cited by 282 · see citing works

Macrophages, Chronic Inflammation, and Insulin Resistance

He, L., Meng, Y., He, S., Tan, X., Zhang, Y., Zhang, X., Wang, L., & Zheng, W. (2022) · Cells · doi:10.3390/cells11193001 · Cited by 278 · see citing works

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

Sierra-Filardi, E., Puig-Kröger, A., Blanco, F. J., Nieto, C., Bragado, R., Palomero, M. I., Bernabéu, C., Vega, M. A., & Corbí, A. L. (2011) · Blood · doi:10.1182/blood-2010-09-306993 · Cited by 268 · see citing works

The Ischemic Environment Drives Microglia and Macrophage Function

Fumagalli, S., Perego, C., Pischiutta, F., Zanier, E. R., & Simoni, M. G. D. (2015) · Frontiers in Neurology · doi:10.3389/fneur.2015.00081 · Cited by 245 · see citing works

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

Pena, O. M., Pistolic, J., Raj, D., Fjell, C. D., & Hancock, R. E. W. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1001952 · Cited by 238 · see citing works

Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators

Suh, H.-S., Zhao, M.-L., Derico, L., Choi, N., & Lee, S. C. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-37 · Cited by 226 · see citing works

The role of tumor-associated macrophages in tumor immune evasion

Huang, R., Kang, T., & Chen, S. (2024) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-024-05777-4 · Cited by 228 · see citing works

Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization

Philipp, D., Suhr, L., Wahlers, T., Choi, Y.-H., & Paunel-Görgülü, A. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-1039-2 · Cited by 213 · see citing works

Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

Lee, C., Jeong, H., Bae, Y., Shin, K., Kang, S., Kim, H., Oh, J., & Bae, H. (2019) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-019-0610-4 · Cited by 211 · see citing works

Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release

Sierra‐Filardi, E., Vega, M. A., Sánchez‐Mateos, P., Corbí, A. L., & Puig‐Kröger, A. (2010) · Immunobiology · doi:10.1016/j.imbio.2010.05.020 · Cited by 204 · see citing works

Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds

Chanput, W. P., Mes, J. J., Savelkoul, H. F. J., & Wichers, H. J. (2012) · Food & Function · doi:10.1039/c2fo30156c · Cited by 190 · see citing works

Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue

Sinha, M., Sen, C. K., Singh, K., Das, A., Ghatak, S., Rhea, B., Blackstone, B. N., Powell, H. M., Khanna, S., & Roy, S. (2018) · Nature Communications · doi:10.1038/s41467-018-03208-w · Cited by 179 · see citing works

New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation

Ariel, A., & Serhan, C. N. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00004 · Cited by 184 · see citing works

Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages

Li, P., Hao, Z., Wu, J., Ma, C., Xu, Y., Li, J., Lan, R., Zhu, B., Ren, P., Fan, D., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.700009 · Cited by 177 · see citing works

Alternative activation of tumor-associated macrophages by IL-4

Wang, H., & Joyce, J. A. (2010) · Cell Cycle · doi:10.4161/cc.9.24.14322 · Cited by 177 · see citing works

Human Chitinases and Chitinase-Like Proteins as Indicators for Inflammation and Cancer

Kzhyshkowska, J. G., Gratchev, A. N., & Goerdt, S. (2007) · Biomarker Insights · doi:10.1177/117727190700200023 · Cited by 171 · see citing works

Peptide-Functionalized Gold Nanorods Increase Liver Injury in Hepatitis

Bartneck, M., Ritz, T., Keul, H. A., Wambach, M., Bornemann, J., Gbureck, U., Ehling, J., Lammers, T., Heymann, F., Gaßler, N., et al. (2012) · ACS Nano · doi:10.1021/nn302502u · Cited by 168 · see citing works

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

Burleigh, A., Chanalaris, A., Gardiner, M. D., Driscoll, C., Boruc, O., Saklatvala, J., & Vincent, T. L. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34420 · Cited by 161 · see citing works

Acute injury in the peripheral nervous system triggers an alternative macrophage response

Ydens, E., Cauwels, A., Asselbergh, B., Goethals, S., Peeraer, L., Lornet, G., Almeida-Souza, L., Ginderachter, J. A. V., Timmerman, V., & Janssens, S. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-176 · Cited by 163 · see citing works

Microglia activation states and cannabinoid system: Therapeutic implications

Mecha, M., Carrillo-Salinas, F. J., Feliú, A., Mestre, L., & Guaza, C. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.06.011 · Cited by 160 · see citing works

Human chitinases and chitinase-like proteins as indicators for inflammation and cancer.

Kzhyshkowska, J. G., Gratchev, A. N., & Goerdt, S. (2007) · PubMed Central · Cited by 154 · see citing works

Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease

Pothoven, K. L., Norton, J. E., Suh, L. A., Carter, R. G., Harris, K. E., Biyasheva, A., Welch, K. C., Smith, S. S., Conley, D. B., Liu, M. C., et al. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.10.039 · Cited by 153 · see citing works

Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation

Becerra-Díaz, M., Strickland, A. B., Keselman, A. M., & Heller, N. M. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800352 · Cited by 149 · see citing works

Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity

Junttila, I., Mizukami, K., Dickensheets, H. L., Meier‐Schellersheim, M., Yamane, H., Donnelly, R. P., & Paul, W. E. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20080452 · Cited by 148 · see citing works

M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer

Ohashi, T., Aoki, M., Tomita, H., Akazawa, T., Sato, K., Kuze, B., Mizuta, K., Hara, A., Nagaoka, H., Inoue, N., et al. (2017) · Cancer Science · doi:10.1111/cas.13244 · Cited by 142 · see citing works

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases

Bartneck, M., Scheyda, K. M., Warzecha, K. T., Rizzo, L. Y., Hittatiya, K., Luedde, T., Storm, G., Trautwein, C., Lammers, T., & Tacke, F. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.030 · Cited by 141 · see citing works

Effect of Cytokine Interplay on Macrophage Polarization during Chronic Pulmonary Infection with Cryptococcus neoformans

Arora, S., Olszewski, M. A., Tsang, T. M., McDonald, R. A., Toews, G. B., & Huffnagle, G. B. (2011) · Infection and Immunity · doi:10.1128/iai.01270-10 · Cited by 140 · see citing works

Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms

Balce, D. R., Li, B., Allan, E. R. O., Rybicka, J. M., Krohn, R. M., & Yates, R. M. (2011) · Blood · doi:10.1182/blood-2011-01-328906 · Cited by 131 · see citing works

Alternatively Activated Macrophages and Airway Disease

Byers, D. E., & Holtzman, M. J. (2011) · CHEST Journal · doi:10.1378/chest.10-2132 · Cited by 128 · see citing works

Macrophage functions in wound healing

Kloc, M., Ghobrial, R. M., Wosik, J., Lewicka, A., Lewicki, S., & Kubiak, J. Z. (2018) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2772 · Cited by 131 · see citing works

Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation

Milner, J. D., Orekov, T., Ward, J. M., Cheng, L., Torres-Velez, F. J., Junttila, I., Sun, G., Buller, M., Morris, S. C., Finkelman, F. D., et al. (2010) · Blood · doi:10.1182/blood-2009-11-255174 · Cited by 115 · see citing works

Functional Immune Anatomy of the Liver—As an Allograft

Demetris, A. J., Bellamy, C. O. C., Gandhi, C. R., Prost, S., Nakanuma, Y., & Stolz, D. B. (2016) · American Journal of Transplantation · doi:10.1111/ajt.13749 · Cited by 115 · see citing works

Morphologic, phenotypic, and transcriptomic characterization of classically and alternatively activated canine blood-derived macrophages in vitro

Heinrich, F., Lehmbecker, A., Raddatz, B. B., Kegler, K., Tipold, A., Stein, V. M., Kalkuhl, A., Deschl, U., Baumgärtner, W., Ulrich, R., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0183572 · Cited by 110 · see citing works

Porphyromonas gingivalis Lipopolysaccharide Weakly Activates M1 and M2 Polarized Mouse Macrophages but Induces Inflammatory Cytokines

Holden, J. A., Attard, T. J., Laughton, K. M., Mansell, A. S., O’brien-simpson, N. M., & Reynolds, E. C. (2014) · Infection and Immunity · doi:10.1128/iai.02325-14 · Cited by 107 · see citing works

Induction of Alternatively Activated Macrophages Enhances Pathogenesis during Severe Acute Respiratory Syndrome Coronavirus Infection

Page, C., Goicochea, L., Matthews, K. L., Zhang, Y., Klover, P. J., Holtzman, M. J., Hennighausen, L. G., & Frieman, M. B. (2012) · Journal of Virology · doi:10.1128/jvi.01689-12 · Cited by 102 · see citing works

Immunomodulatory Biomaterials: Tailoring Surface Properties to Mitigate Foreign Body Reaction and Enhance Tissue Regeneration

Amani, H., Alipour, M., Shahriari, E., & Taboas, J. M. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401253 · Cited by 107 · see citing works

Hepatic Localization of Macrophage Phenotypes during Fibrogenesis and Resolution of Fibrosis in Mice and Humans

Beljaars, L., Schippers, M., Reker‐Smit, C., Martínez, F. O., Helming, L., Poelstra, K., & Melgert, B. N. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00430 · Cited by 97 · see citing works

Anti-inflammatory and immunosuppressive activation of human monocytes by a bioactive dendrimer

Fruchon, S., Poupot, M., Martinet, L., Turrin, C., Majoral, J., Fournié, J., Caminade, A., & Poupot, R. (2008) · Journal of Leukocyte Biology · doi:10.1189/jlb.0608371 · Cited by 100 · see citing works

Diabetic and idiopathic gastroparesis is associated with loss of <scp>CD</scp>206‐positive macrophages in the gastric antrum

Grover, M., Bernard, C. E., Pasricha, P. J., Parkman, H. P., Gibbons, S. J., Tonascia, J., Koch, K. L., McCallum, R. W., Sarosiek, I., Hasler, W. L., et al. (2017) · Neurogastroenterology &amp; Motility · doi:10.1111/nmo.13018 · Cited by 98 · see citing works

Selective inhibition and augmentation of alternative macrophage activation by progesterone

Menzies, F. M., Henriquez, F., Alexander, J., & Roberts, C. W. (2011) · Immunology · doi:10.1111/j.1365-2567.2011.03488.x · Cited by 85 · see citing works

Mechano-Immunomodulation: Mechanoresponsive Changes in Macrophage Activity and Polarization

Adams, S., Wuescher, L. M., Worth, R., & Yildirim-Ayan, E. (2019) · Annals of Biomedical Engineering · doi:10.1007/s10439-019-02302-4 · Cited by 96 · see citing works

Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor Phenotype

Paolini, L., Adam, C., Beauvillain, C., Preisser, L., Blanchard, S., Pignon, P., Seegers, V., Chevalier, L.-M., Campone, M., Wernert, R., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0749 · Cited by 96 · see citing works

Alternatively Activated and Immunoregulatory Monocytes in Human Filarial Infections

Babu, S., Kumaraswami, V., & Nutman, T. B. (2009) · The Journal of Infectious Diseases · doi:10.1086/599090 · Cited by 95 · see citing works

The biology of the Gaucher cell: the cradle of human chitinases.

Bussink, A. P., van Eijk, M., Renkema, G., Aerts, J., & Boot, R. (2006) · International Review of Cytology · doi:10.1016/s0074-7696(06)52001-7 · Cited by 106 · see citing works

The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Attenuates Inflammation and Accelerates Epithelialization in Wounds of Diabetic ob/ob Mice

Schürmann, C., Linke, A., Engelmann-Pilger, K., Steinmetz, C., Mark, M., Pfeilschifter, J. M., Klein, T., & Frank, S. (2012) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.111.191098 · Cited by 90 · see citing works

M2 Polarization of Monocytes-Macrophages Is a Hallmark of Indian Post Kala-Azar Dermal Leishmaniasis

Mukhopadhyay, D., Mukherjee, S., Roy, S., Dalton, J. E., Kundu, S., Sarkar, A., Das, N. K., Kaye, P. M., & Chatterjee, M. (2015) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0004145 · Cited by 91 · see citing works

Sequential expression of macrophage anti-microbial/inflammatory and wound healing markers following innate, alternative and classical activation

Menzies, F. M., Henriquez, F. L., Alexander, J., & Roberts, C. W. (2010) · Clinical and Experimental Immunology · doi:10.1111/j.1365-2249.2009.04086.x · Cited by 90 · see citing works

Ex Vivo and In Vitro Effect of Serum Amyloid A in the Induction of Macrophage M2 Markers and Efferocytosis of Apoptotic Neutrophils

Sun, L., Zhou, H., Zhu, Z., Qian, Y., Wang, L., Liang, Q., & Ye, R. D. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402164 · Cited by 90 · see citing works

Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells - Response

Scotton, C. J., Locati, M., Mantovani, A., & Sozzani, S. (2005) · UCL Discovery (University College London)

Transcriptional Profiling Reveals Complex Regulation of the Monocyte IL-1β System by IL-13

Scotton, C. J., Martínez, F. O., Smelt, M. J., Sironi, M., Locati, M., Mantovani, A., & Sozzani, S. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.2.834 · Cited by 138 · see citing works

IL-13-Mediated Arginase I Induction in Macrophages:

Chang, C.-I., Zoghi, B., Liao, J. C., Kuo, L., Immunol, J., Chang, C.-I., Zoghi, B., Liao, J. C., & Kuo, L. (2013)

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

Bhattacharjee, A., Shukla, M., Yakubenko, V. P., Mulya, A., Kundu, S., & Cathcart, M. K. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.10.553 · Cited by 237 · see citing works

M-MDSC in vitro generation from mouse bone marrow with IL-3 reveals high expression and functional activity of arginase 1

Aintablian, A., Strozniak, S., Heuer, M., & Lutz, M. B. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1130600 · Cited by 9 · see citing works