The Epidemiology of Chronic Major Depressive Disorder and Dysthymic Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

Blanco, Carlos; Okuda, Mayumi; Markowitz, John C.; Liu, Shang-Min; Grant, Bridget F.; Hasin, Deborah S.

doi:10.4088/jcp.09m05663gry

Cited by 144Mental Health Treatment and AccessTreatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The Epidemiology of Chronic Major Depressive Disorder and Dysthymic Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

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Blanco, Carlos, Okuda, Mayumi, Markowitz, John C., Liu, Shang-Min, Grant, Bridget F., Hasin, Deborah S.·2010·The Journal of Clinical Psychiatry

DOI 10.4088/jcp.09m05663gryPMC PMC3202750

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Article AbstractObjective: To examine the prevalence of chronic major depressive disorder (CMDD) and dysthymic disorder, their sociodemographic correlates, patterns of 12-month and lifetime psychiatric comorbidity, lifetime risk factors, psychosocial functioning, and mental health service utilization. Method: Face-to-face interviews were conducted in the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (n = 43,093). Results: The 12-month and lifetime prevalences were greater for CMDD (1.5% and 3.1%, respectively) than for dysthymic disorder (0.5% and 0.9%, respectively). Individuals with CMDD and dysthymic disorder shared most sociodemographic correlates and lifetime risk factors for major depressive disorder. Individuals with CMDD and dysthymic disorder had almost identically high rates of Axis I and Axis II comorbid disorders. However, individuals with CMDD received higher rates of all treatment modalities than individuals with dysthymic disorder. Conclusions: Individuals with CMDD and dysthymic disorder share many sociodemographic correlates, comorbidity patterns, risk factors, and course. Individuals with chronic depressive disorders, especially those with dysthymic disorder, continue to face substantial unmet treatment needs.J Clin Psychiatry 2010;71(12):1645-1656Submitted: September 2, 2009; accepted November 10, 2009 (doi:10.4088/JCP.09m05663gry). Corresponding author: Bridget F. Grant, PhD, PhD, Laboratory of Epidemiology and Biometry, Room 3077, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, MS 9304, 5635 Fishers Lane, Bethesda, MD 20892-9304 (bgrant@willco.niaaa.nih.gov)

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Major Depressive Disorder (MDD) is prevalent, often chronic, and requires ongoing monitoring of symptoms to track response to treatment and identify early indicators of relapse.
“Major Depressive Disorder (MDD) is prevalent, often chronic, and requires ongoing monitoring of symptoms to track response to treatment and identify early indicators of relapse.”
From Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): recruitment, retention, and data availability in a longitudinal remote measurement study (2022) · cites this paper as [7]

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Authors: Blanco, C., Okuda, M., Markowitz, J. C., Liu, S.-M., Grant, B. F., & Hasin, D. S.
Affiliations: New York State Psychiatric Institute (US)
Cornell University (US)
National Institutes of Health (US)
Corresponding author: Grant, Bridget F.
ORCID: Blanco, Carlos
Okuda, Mayumi
Markowitz, John C.
Hasin, Deborah S.
Venue: The Journal of Clinical Psychiatry
Publisher: Physicians Postgraduate Press, Inc
Published: 2010-12-15
Volume: 71
Issue: 12
Pages: 1645-1656
ISSN: 0160-6689 (ISSN-L)
DOI: 10.4088/jcp.09m05663gry
PMC: PMC3202750
OpenAlex: W2023962999
Cited by: 144
References: 72
Citations by year: 2026: 4 · 2025: 7 · 2024: 6 · 2023: 14 · 2022: 13 · 2021: 3 · 2020: 5 · 2019: 6 · 2018: 13 · 2017: 8 · 2016: 15 · 2015: 10 · 2014: 5 · 2013: 13 · 2012: 11
FWCI: 13.99
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: The Journal of Clinical Psychiatry (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Institute on Alcohol Abuse and Alcoholism (Z01AA000449, AA014223-03, K05AA014223)
National Institute of Mental Health (MH076051, R01MH076051, R01MH079078, MH-079078)
National Institute on Drug Abuse (R01DA020783, DA019606, R01DA023973, DA020783, DA023200, R01DA019606, DA023973, K02DA023200)
Topics: Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: dysthymia, prevalence, sociodemographic correlates, psychiatric comorbidity, psychosocial functioning, mental health service utilization, unmet treatment needs, NESARC
MeSH terms: Adult, Aged, Aged, 80 and over, Chronic Disease, Depressive Disorder, Major, Major Depressive Disorder, Female, Health Services Needs and Demand, Health Surveys, Humans, Male, Mental Health Services, Middle Aged, Psychiatric Status Rating Scales, Risk Factors, Sampling Studies, Social Class, United States, Comorbidity, Prevalence, Dysthymic Disorder, Diagnostic and Statistical Manual of Mental Disorders

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The Epidemiology of Chronic Major Depressive Disorder and Dysthymic Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

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