The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.
Application of Nanotechnology in Cancer Diagnosis and Therapy - A Mini-Review
Open accessAbstract
Cancer is a leading cause of death and poor quality of life globally. Even though several strategies are devised to reduce deaths, reduce chronic pain and improve the quality of life, there remains a shortfall in the adequacies of these cancer therapies. Among the cardinal steps towards ensuring optimal cancer treatment are early detection of cancer cells and drug application with high specificity to reduce toxicities. Due to increased systemic toxicities and refractoriness with conventional cancer diagnostic and therapeutic tools, other strategies including nanotechnology are being employed to improve diagnosis and mitigate disease severity. Over the years, immunotherapeutic agents based on nanotechnology have been used for several cancer types to reduce the invasiveness of cancerous cells while sparing healthy cells at the target site. Nanomaterials including carbon nanotubes, polymeric micelles and liposomes have been used in cancer drug design where they have shown considerable pharmacokinetic and pharmacodynamic benefits in cancer diagnosis and treatment. In this review, we outline the commonly used nanomaterials which are employed in cancer diagnosis and therapy. We have highlighted the suitability of these nanomaterials for cancer management based on their physicochemical and biological properties. We further reviewed the challenges that are associated with the various nanomaterials which limit their uses and hamper their translatability into the clinical setting in certain cancer types.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21492 · Cited by 84,109
Proceedings of the National Academy of Sciences of the United States of America
Dowling, J. E., & Wald, G. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1981.tb06752.x · Cited by 17,893
Quantum dot bioconjugates for imaging, labelling and sensing
Medintz, I. L., Uyeda, H. T., Goldman, E. R., & Mattoussi, H. (2005) · Nature Materials · doi:10.1038/nmat1390 · Cited by 6,229
Liposomal drug delivery systems: From concept to clinical applications
Allen, T. M., & Cullis, P. R. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.037 · Cited by 4,839
In vivo cancer targeting and imaging with semiconductor quantum dots
Gao, X., Cui, Y., Levenson, R. M., Chung, L. W. K., & Nie, S. (2004) · Nature Biotechnology · doi:10.1038/nbt994 · Cited by 4,772
Nanoparticle therapeutics: an emerging treatment modality for cancer
Davis, M. E., Chen, Z., & Shin, D. M. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2614 · Cited by 4,233
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Hirsch, L. R., Stafford, R. J., Bankson, J. A., Sershen, S. R., Rivera, B., Price, R. E., Hazle, J. D., Halas, N. J., & West, J. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2232479100 · Cited by 3,955
A New Class of Polymers: Starburst-Dendritic Macromolecules
Tomalia, D. A., Baker, H., Dewald, J., Hall, M., Kallos, G., Martin, S., Roeck, J., Ryder, J., & Smith, P. (1985) · Polymer Journal · doi:10.1295/polymj.17.117 · Cited by 3,904
The dawning era of polymer therapeutics
Duncan, R. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1088 · Cited by 3,269
In Vivo Imaging of Quantum Dots Encapsulated in Phospholipid Micelles
Dubertret, B., Skourides, P., Norris, D. J., Noireaux, V., Brivanlou, A. H., & Libchaber, A. (2002) · Science · doi:10.1126/science.1077194 · Cited by 3,019
International Journal of Nanomedicine
(2020) · International Journal of Nanomedicine · doi:10.2147/ijn · Cited by 2,747
International Journal of Pharmaceutics
He, W., Yang, K., Fan, L., Lv, Y., Zhu, J., Zhu, S., Qin, C., Wang, Y., & Yin, L. (2015) · Cited by 2,639
Kam, N. W. S., O'Connell, M., Wisdom, J. A., & Dai, H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502680102 · Cited by 2,307
Liposomes as nanomedical devices
Bozzuto, G., & Molinari, A. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s68861 · Cited by 2,261
Applications of Carbon Nanotubes in Drug Delivery
Kaur, J., Gill, G. S., & Jeet, K. (2019) · Characterization and Biology of Nanomaterials for Drug Delivery · doi:10.1016/b978-0-12-814031-4.00005-2 · Cited by 2,019
New-Concept Chemotherapy by Nanoparticles of Biodegradable Polymers: Where Are We Now?
Feng, S.-S. (2006) · Nanomedicine · doi:10.2217/17435889.1.3.297 · Cited by 1,951
Dendrimers in biomedical applications—reflections on the field
SVENSON, S., & TOMALIA, D. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.09.018 · Cited by 1,919
Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer
Malam, Y., Loizidou, M., & Seifalian, A. M. (2009) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2009.08.004 · Cited by 1,318
Polymeric micelles—A new generation of colloidal drug carriers
Jones, M.-C., & Leroux, J.-C. (1999) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(99)00039-9 · Cited by 1,256
Nanoshell-Enabled Photonics-Based Imaging and Therapy of Cancer
Loo, C., Lin, A., Hirsch, L., Lee, M.-H., Barton, J., Halas, N., West, J., & Drezek, R. (2004) · Technology in Cancer Research & Treatment · doi:10.1177/153303460400300104 · Cited by 1,160
Micellar Nanocontainers Distribute to Defined Cytoplasmic Organelles
Savić, R., Luo, L., Eisenberg, A., & Maysinger, D. (2003) · Science · doi:10.1126/science.1078192 · Cited by 1,113
Lancet, J. E., Uy, G. L., Cortes, J. E., Newell, L. F., Lin, T. L., Ritchie, E. K., Stuart, R. K., Strickland, S. A., Hogge, D., Solomon, S. R., et al. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2017.77.6112 · Cited by 1,025
Beg, M. S., Brenner, A. J., Sachdev, J., Borad, M., Kang, Y.-K., Stoudemire, J., Smith, S., Bader, A. G., Kim, S., & Hong, D. S. (2017) · Investigational New Drugs · doi:10.1007/s10637-016-0407-y · Cited by 897
Cancer nanomedicine: A review of recent success in drug delivery
Tran, S., DeGiovanni, P., Piel, B., & Rai, P. (2017) · Clinical and Translational Medicine · doi:10.1186/s40169-017-0175-0 · Cited by 879
Dendritic macromolecules: synthesis of starburst dendrimers
Tomalia, D. A., Baker, H., Dewald, J., Hall, M., Kallos, G., Martin, S., Roeck, J., Ryder, J., & Smith, P. (1986) · Macromolecules · doi:10.1021/ma00163a029 · Cited by 876
Kim, D., Jeong, Y. Y., & Jon, S. (2010) · ACS Nano · doi:10.1021/nn901877h · Cited by 726
Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy
Palmerston Mendes, L., Pan, J., & Torchilin, V. (2017) · Molecules · doi:10.3390/molecules22091401 · Cited by 701
Quintana, A., Raczka, E., Piehler, L., Lee, I., Myc, A., Majoros, I., Patri, A. K., Thomas, T., Mulé, J., & Baker, J. R. (2002) · Pharmaceutical Research · doi:10.1023/a:1020398624602 · Cited by 663
Nanoparticles for drug delivery to the lungs
Sung, J. C., Pulliam, B. L., & Edwards, D. A. (2007) · Trends in Biotechnology · doi:10.1016/j.tibtech.2007.09.005 · Cited by 643
Development of the polymer micelle carrier system for doxorubicin
Nakanishi, T., Fukushima, S., Okamoto, K., Suzuki, M., Matsumura, Y., Yokoyama, M., Okano, T., Sakurai, Y., & Kataoka, K. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00341-8 · Cited by 570
Annual Review of Biomedical Engineering
(2017) · Annual Review of Biomedical Engineering · doi:10.1146/bioeng.685 · Cited by 553
Quantum Size Effect in Three-Dimensional Microscopic Semiconductor Crystals
Ekimov, A. I., & Onushchenko, A. A. (2023) · JETP Letters · doi:10.1134/s0021364023130040 · Cited by 516
Polymeric micelles for nano-scale drug delivery
Miyata, K., Christie, R. J., & Kataoka, K. (2011) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2010.10.009 · Cited by 478
Cancer Nanotechnology: A New Revolution for Cancer Diagnosis and Therapy
Chaturvedi, V. K., Singh, A., Singh, V. K., & Singh, M. P. (2019) · Current Drug Metabolism · doi:10.2174/1389200219666180918111528 · Cited by 418
Critical Reviews in Therapeutic Drug Carrier Systems
Sachdeva, M. S., & Zucolotto, V. (2020) · Cited by 396
On the Cyto‐Toxicity Caused by Quantum Dots
Shiohara, A., Hoshino, A., Hanaki, K., Suzuki, K., & Yamamoto, K. (2004) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2004.tb03478.x · Cited by 385 · cited 1×
“With the improvement of multiplexing capability, QDs conjugation greatly exceeds the monochromatic experiment in both time and cost-effectiveness[90].”
BackgroundRecent advances in dendrimer-based nanovectors for tumor-targeted drug and gene delivery
Kesharwani, P., & Iyer, A. K. (2015) · Drug Discovery Today · doi:10.1016/j.drudis.2014.12.012 · Cited by 380
Dendrimers: A versatile nanocarrier for drug delivery and targeting
Sherje, A. P., Jadhav, M., Dravyakar, B. R., & Kadam, D. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.07.030 · Cited by 373
Chemical Exchange Saturation Transfer Contrast Agents for Magnetic Resonance Imaging
Sherry, A. D., & Woods, M. (2008) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.151929 · Cited by 356
Nanoparticle therapeutics: an emerging treatment modality for cancer
Davis, M. E., Chen, Z. (., & Shin, D. M. (2009) · Nanoscience and Technology · doi:10.1142/9789814287005_0025 · Cited by 321
An investigation into the human serum “interactome”
Zhou, M., Lucas, D. A., Chan, K. C., Issaq, H. J., Petricoin, E. F., Liotta, L. A., Veenstra, T. D., & Conrads, T. P. (2004) · ELECTROPHORESIS · doi:10.1002/elps.200405866 · Cited by 313
Early Detection of Ovarian Cancer
Badgwell, D., & Bast, R. C. (2007) · Disease Markers · doi:10.1155/2007/309382 · Cited by 294
Jokerst, J. V., Raamanathan, A., Christodoulides, N., Floriano, P. N., Pollard, A. A., Simmons, G. W., Wong, J., Gage, C., Furmaga, W. B., Redding, S. W., et al. (2009) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2009.05.026 · Cited by 253
Fenske, D. B., & Cullis, P. R. (2008) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.5.1.25 · Cited by 253
Bharali, D. J., & Mousa, S. A. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.07.007 · Cited by 251
Berry, G., Billingham, M., Alderman, E., Richardson, P., Torti, F., Lum, B., Patek, A., & Martin, F. J. (1998) · Annals of Oncology · doi:10.1023/a:1008216430806 · Cited by 241
Targeting Dendrimer-Chelates to Tumors and Tumor Cells Expressing the High-Affinity Folate Receptor
WIENER, E. C., KONDA, S., SHADRON, A., BRECHBIEL, M., & GANSOW, O. (1997) · INVESTIGATIVE RADIOLOGY · doi:10.1097/00004424-199712000-00005 · Cited by 214
Design of Dendritic Macromolecules Containing Folate or Methotrexate Residues
Kono, K., Liu, M., & Fréchet, J. M. J. (1999) · Bioconjugate Chemistry · doi:10.1021/bc990082k · Cited by 207
Nanoparticles for Tumor Targeted Therapies and Their Pharmacokinetics
Wang, J., Sui, M., & Fan, W. (2010) · Current Drug Metabolism · doi:10.2174/138920010791110827 · Cited by 205
Yu, X., Gao, D., Gao, L., Lai, J., Zhang, C., Zhao, Y., Zhong, L., Jia, B., Wang, F., Chen, X., et al. (2017) · ACS Nano · doi:10.1021/acsnano.7b04736 · Cited by 192
Chen, C., Peng, J., Xia, H.-S., Yang, G.-F., Wu, Q.-S., Chen, L.-D., Zeng, L.-B., Zhang, Z.-L., Pang, D.-W., & Li, Y. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.010 · Cited by 177
Cardiac safety of liposomal anthracyclines
Ewer, M. S., Martin, F. J., Henderson, I. C., Shapiro, C. L., Benjamin, R. S., & Gabizon, A. A. (2004) · Seminars in Oncology · doi:10.1053/j.seminoncol.2004.08.006 · Cited by 160
Hu, J., Huang, S., Zhu, L., Huang, W., Zhao, Y., Jin, K., & ZhuGe, Q. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b09423 · Cited by 159
Self-citationSung, S., Su, Y., Cheng, W., Hu, P.-F., Chiang, C., Chen, W., & Hu, S. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b03249 · Cited by 154
Nanomedicines as Cancer Therapeutics: Current Status
Akhter, S., Ahmad, I., Ahmad, M. Z., Ramazani, F., Singh, A., Rahman, Z., Ahmad, F. J., Storm, G., & Kok, R. J. (2013) · Current Cancer Drug Targets · doi:10.2174/1568009611313040002 · Cited by 149
β-Lapachone Micellar Nanotherapeutics for Non–Small Cell Lung Cancer Therapy
Blanco, E., Bey, E. A., Khemtong, C., Yang, S.-G., Guthi, J. S., Chen, H., Kessinger, C. W., Carnevale, K. A., Bornmann, W. G., Boothman, D. A., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-3995 · Cited by 147
Fujiwara, Y., Mukai, H., Saeki, T., Ro, J., Lin, Y.-C., Nagai, S. E., Lee, K. S., Watanabe, J., Ohtani, S., Kim, S. B., et al. (2019) · British Journal of Cancer · doi:10.1038/s41416-019-0391-z · Cited by 147
Greil, R., Greil‐Ressler, S., Weiß, L., Schönlieb, C., Magnes, T., Radl, B., Bolger, G. T., Vcelar, B. A., & Sordillo, P. P. (2018) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-018-3654-0 · Cited by 143
Mining the Ovarian Cancer Ascites Proteome for Potential Ovarian Cancer Biomarkers
Kuk, C., Kulasingam, V., Gunawardana, C. G., Smith, C. R., Batruch, I., & Diamandis, E. P. (2008) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m800313-mcp200 · Cited by 132
Advances in nanotechnology for cancer biomarkers
Ye, F., Zhao, Y. H., El-Sayed, R., Muhammed, M. A., & Hassan, M. (2018) · Nano Today · doi:10.1016/j.nantod.2017.12.008 · Cited by 129
Gargett, T., Abbas, M. N., Rolan, P. E., Price, J. D., Gosling, K. M., Ferrante, A., Ruszkiewicz, A. R., Atmosukarto, I. I., Altin, J. G., Parish, C. R., et al. (2018) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-018-2207-z · Cited by 116
Zhang, Y., Yang, H., An, X., Wang, Z., Yang, X., Yu, M., Zhang, R., Sun, Z., & Wang, Q. (2020) · Small · doi:10.1002/smll.202001003 · Cited by 116
Polyalkylcyanoacrylates as colloidal drug carriers.
Couvreur, P. (1988) · PubMed · Cited by 110
Liposomes as targeted drug delivery systems in the treatment of breast cancer
Sharma, G., Anabousi, S., Ehrhardt, C., & Kumar, M. N. V. R. (2006) · Journal of drug targeting · doi:10.1080/10611860600809112 · Cited by 107
Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors
Garrigue, P., Tang, J., Ding, L., Bouhlel, A., Tintaru, A., Laurini, E., Huang, Y., Lyu, Z., Zhang, M., Fernandez-Sauze, S., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1812938115 · Cited by 103
Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers
Longo, C., Patanarut, A., George, T., Bishop, B., Zhou, W., Fredolini, C., Ross, M. M., Espina, V. A., Pellacani, G., Petricoin, E. F., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004763 · Cited by 101
Lee, S., Kim, Y., Cho, C., Kim, Y. T., Kim, S. M., Hur, S. Y., Kim, J., Kim, B., Kim, S. C., Ryu, H., et al. (2017) · Cancer Research and Treatment · doi:10.4143/crt.2016.376 · Cited by 100
Karnati, K. R., & Wang, Y. (2018) · Physical Chemistry Chemical Physics · doi:10.1039/c8cp00124c · Cited by 98
Terracciano, R., Gaspari, M., Testa, F., Pasqua, L., Tagliaferri, P., Cheng, M. M., Nijdam, A. J., Petricoin, E. F., Liotta, L. A., Cuda, G., et al. (2006) · PROTEOMICS · doi:10.1002/pmic.200500614 · Cited by 96
Stocke, N. A., Meenach, S. A., Arnold, S. M., Mansour, H. M., & Hilt, J. Z. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.12.050 · Cited by 91
Mukai, H., Kogawa, T., Matsubara, N., Naito, Y., Sasaki, M., & Hosono, A. (2017) · Investigational New Drugs · doi:10.1007/s10637-016-0422-z · Cited by 90
Qian, Z., Wang, X., Song, Z., Zhang, H., Zhou, S., Zhao, J., & Wang, H. (2015) · BioMed Research International · doi:10.1155/2015/809714 · Cited by 88
Cornely, O. A., Leguay, T., Maertens, J. A., Vehreschild, M. J. G. T., Anagnostopoulos, Α., Castagnola, C., Verga, L., Rieger, C. T., Kondakci, M., Härter, G., et al. (2017) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkx133 · Cited by 86
Shah, N. N., Merchant, M. S., Cole, D. E., Jayaprakash, N., Bernstein, D. B., Delbrook, C., Richards, K., Widemann, B. C., & Wayne, A. S. (2016) · Pediatric Blood & Cancer · doi:10.1002/pbc.25937 · Cited by 81
The amplified peptidome: the new treasure chest of candidate biomarkers
Geho, D. H., Liotta, L. A., Petricoin, E. F., ZHAO, W., & Araujo, R. P. (2006) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2006.01.008 · Cited by 79
Nanoporous Surfaces as Harvesting Agents for Mass Spectrometric Analysis of Peptides in Human Plasma
Gaspari, M., Cheng, M. M., Terracciano, R., Liu, X., Nijdam, A. J., Vaccari, L., Fabrizio, E. M. D., Petricoin, E. F., Liotta, L. A., Cuda, G., et al. (2006) · Journal of Proteome Research · doi:10.1021/pr050417+ · Cited by 75
Kim, H. S., Oh, S. Y., Joo, H. J., Son, K.-R., Song, I. C., & Moon, W. K. (2010) · NMR in Biomedicine · doi:10.1002/nbm.1487 · Cited by 70
Mahner, S., Meier, W., du Bois, A., Brown, C., Lorusso, D., Dell’Anna, T., Cretin, J., Havsteen, H., Bessette, P., Zeimet, A. G., et al. (2015) · European Journal of Cancer · doi:10.1016/j.ejca.2014.11.017 · Cited by 70
Jafari, A., Salouti, M., Shayesteh, S. F., Heidari, Z., Bitarafan‐Rajabi, A., Boustani, K., & Nahardani, A. (2015) · Nanotechnology · doi:10.1088/0957-4484/26/7/075101 · Cited by 70
Nanotechnology based therapeutic application in cancer diagnosis and therapy
Singh, R. (2019) · 3 Biotech · doi:10.1007/s13205-019-1940-0 · Cited by 70
Hu, J., Huang, W., Huang, S., Zhuge, Q., Jin, K., & Zhao, Y. (2016) · Nano Research · doi:10.1007/s12274-016-1152-4 · Cited by 69
Self-citationNanoparticles: potential biomarker harvesters
Geho, D. H., Jones, C. D., Petricoin, E. F., & Liotta, L. A. (2006) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2006.01.003 · Cited by 67
Nanomaterial applications for neurological diseases and central nervous system injury
Huang, L., Hu, J., Huang, S., Wang, B. Z., Siaw-Debrah, F., Nyanzu, M. K., Zhang, Y., & Zhuge, Q. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.07.003 · Cited by 66
Self-citationHaq, M. N. U., Rainer, M., Szabó, Z., Vallant, R. M., Huck, C. W., & Bonn, G. K. (2006) · Journal of Biochemical and Biophysical Methods · doi:10.1016/j.jbbm.2006.11.004 · Cited by 65
Ohanian, M. N., Ashizawa, A. T., Garcia‐Manero, G., Pemmaraju, N., Kadia, T. M., Jabbour, E. J., Ravandi, F., Borthakur, G. M., Andreeff, M., Konopleva, M. Y., et al. (2018) · The Lancet Haematology · doi:10.1016/s2352-3026(18)30021-8 · Cited by 63
Ji, T., Zhao, Y., Wang, J., Zheng, X., Tian, Y., Zhao, Y., & Nie, G. (2013) · Small · doi:10.1002/smll.201300600 · Cited by 62
Fredolini, C., Meani, F., Luchini, A., Zhou, W., Russo, P. S., Ross, M. M., Patanarut, A., Tamburro, D., Gambara, G., Ornstein, D. K., et al. (2010) · The AAPS Journal · doi:10.1208/s12248-010-9211-3 · Cited by 62
Golan, T., Grenader, T., Ohana, P., Amitay, Y., Shmeeda, H., La-Beck, N. M., Tahover, E., Berger, R., & Gabizón, A. (2015) · Cancer Medicine · doi:10.1002/cam4.491 · Cited by 61
Nanoparticle Technology: Addressing the Fundamental Roadblocks to Protein Biomarker Discovery
Luchini, A., Fredolini, C., Espina, B., Meani, F., Reeder, A., Rucker, S., Petricoin, E. F., & Liotta, L. A. (2010) · Current Molecular Medicine · doi:10.2174/156652410790963268 · Cited by 59
A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma
Clarke, J. L., Molinaro, A. M., Cabrera, J. R., DeSilva, A. A., Rabbitt, J. E., Prey, J. D., Drummond, D. C., Kim, J., Noble, C. O., Fitzgerald, J. B., et al. (2017) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-017-3247-3 · Cited by 58
Fu, N., Hu, Y., Shi, S., Ren, S., Liu, W., Su, S., Zhao, B., Weng, L., & Wang, L. (2018) · The Analyst · doi:10.1039/c8an00105g · Cited by 55
Michele, M. D., Marcone, S., Cicchillitti, L., Corte, A. D., Ferlini, C., Scambia, G., Donati, M. B., & Rotilio, D. (2009) · Journal of Proteomics · doi:10.1016/j.jprot.2009.11.012 · Cited by 50
Wan, X., Song, Y., Song, N., Li, J., Yang, L., Li, Y., & Tan, H. Q. (2015) · Carbohydrate Research · doi:10.1016/j.carres.2015.11.003 · Cited by 48
Nunes, T., Pons, T., Hou, X., et al. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1305-x · Cited by 47
Krivak, T. C., Smith, A. L., Zorn, K. K., Sukumvanich, P., Olawaiye, A. B., Kelley, J. L., & Berger, J. L. (2014) · OncoTargets and Therapy · doi:10.2147/ott.s62881 · Cited by 42
Chiang, N., Chao, T.-Y., Hsieh, R., Wang, C., Wang, Y.-W., Yeh, C. G., & Chen, L. (2016) · BMC Cancer · doi:10.1186/s12885-016-2933-6 · Cited by 41
A tale of the two PEGylated liposomal doxorubicins
Liu, H., Chou, H., & Lin, H. (2015) · OncoTargets and Therapy · doi:10.2147/ott.s79089 · Cited by 36
Schiller, G. J., Damon, L. E., Coutre, S. E., et al. (2018) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2018.0041 · Cited by 35
van Eijkelenburg, N. K. A., Rasche, M., Ghazaly, E. A., Dworzak, M. N., Klingebiel, T. E., Rössig, C., Leverger, G., Starý, J., de Bont, E. S. J. M., Chitu, D. A., et al. (2018) · Haematologica · doi:10.3324/haematol.2017.187153 · Cited by 33
Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery
Luchini, A., Longo, C., Espina, V. A., Petricoin, E. F., & Liotta, L. A. (2009) · Journal of Materials Chemistry · doi:10.1039/b822264a · Cited by 26
Levinsen, M., Harila‐Saari, A. H., Grell, K., Jónsson, Ó. G., Taskinen, M. H., Abrahamsson, J., Vettenranta, K. K., Åsberg, A. E., Risteli, J., Heldrup, J., et al. (2016) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0000000000000642 · Cited by 26
Recent Advances in Tissue plasminogen activator-based nanothrombolysis for ischemic stroke
Huang, D., Wu, K., Zhang, Y., Ni, Z., Zhu, X., Zhu, C., Yang, J., Zhuge, Q., & Hu, J. (2019) · REVIEWS ON ADVANCED MATERIALS SCIENCE · doi:10.1515/rams-2019-0024 · Cited by 24
Self-citationXiang, Q., Wang, L., Yuan, J., Chen, J., Yang, F., & Li, Y. (2015) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2015.06.013 · Cited by 20
Clinical Application of Proteomics in Ovarian Cancer Prevention and Treatment
Meani, F., Pecorelli, S. L., Liotta, L. A., & Petricoin, E. F. (2009) · Molecular Diagnosis & Therapy · doi:10.1007/bf03256335 · Cited by 20
Cited by
Recent updates on innovative approaches to overcome drug resistance for better outcomes in cancer
Sharma, M., Bakshi, A. K., Mittapelly, N., Gautam, S., Marwaha, D., Rai, N., Singh, N., Tiwari, P., Agarwal, N., Kumar, A., et al. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.04.007 · Cited by 84
Metadata
- Authors
- Jin, C., Wang, K., Oppong-Gyebi, A., & Hu, J.
- Venue
- International Journal of Medical Sciences
- Publisher
- Ivyspring International Publisher
- Published
- 2020
- Volume
- 17
- Issue
- 18
- Pages
- 2964-2973
- ISSN
- 1449-1907 (ISSN-L)
- OpenAlex
- W3095000040
- Cited by
- 353
- References
- 104
- FWCI
- 2.21
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
