The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens

Long-Term Potentiation--A Decade of Progress?

Malenka, R. C., & Nicoll, A. R. A. (1999) · Science · doi:10.1126/science.285.5435.1870 · Cited by 2,729 · see citing works

Structural basis of long-term potentiation in single dendritic spines

Matsuzaki, M., Honkura, N., Ellis-Davies, G. C. R., & Kasai, H. (2004) · Nature · doi:10.1038/nature02617 · Cited by 2,500 · see citing works

Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex

Ikemoto, S. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.05.004 · Cited by 1,477 · see citing works

The many faces of CREB

Carlezon, W. A., Duman, R. S., & Nestler, E. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.06.005 · Cited by 1,351 · see citing works

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

Sheng, M., Cummings, J., Roldan, L. A., Jan, Y. N., & Jan, L. Y. (1994) · Nature · doi:10.1038/368144a0 · Cited by 1,170 · see citing works

A translational profiling approach for the molecular characterization of CNS cell types

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.028 · Cited by 1,134 · see citing works

Transient and persistent dendritic spines in the neocortex in vivo

Holtmaat, A. J. G. D., Trachtenberg, J. T., Wilbrecht, L., Shepherd, G. M., Zhang, X., Knott, G. W., & Svoboda, K. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.003 · Cited by 1,131 · see citing works

Molecular mechanisms of drug addiction

Nestler, E. J. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.031 · Cited by 1,108 · see citing works

Structural plasticity associated with exposure to drugs of abuse

Robinson, T. E., & Kolb, B. E. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.06.025 · Cited by 1,104 · see citing works

Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]

Harris, K. M., Jensen, F. E., & Tsao, B. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-07-02685.1992 · Cited by 990 · see citing works

Plasticity of reward neurocircuitry and the ‘dark side’ of drug addiction

Koob, G. F., & Le Moal, M. (2005) · Nature Neuroscience · doi:10.1038/nn1105-1442 · Cited by 963 · see citing works

Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity

Okamoto, K.-I., Nagai, T., Miyawaki, A., & Hayashi, Y. (2004) · Nature Neuroscience · doi:10.1038/nn1311 · Cited by 854 · see citing works

Do thin spines learn to be mushroom spines that remember?

Bourne, J., & Harris, K. M. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.04.009 · Cited by 843 · see citing works

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T. S., Goodman, R. H., & Impey, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508448102 · Cited by 799 · see citing works

Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving

Conrad, K. L., Tseng, K. Y., Uejima, J. L., Reimers, J. M., Heng, L.-J., Shaham, Y., Marinelli, M., & Wolf, M. E. (2008) · Nature · doi:10.1038/nature06995 · Cited by 790 · see citing works

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

Machesky, L. M., Mullins, R. D., Higgs, H. N., Kaiser, D. A., Blanchoin, L., May, R. C., Hall, M. E., & Pollard, T. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3739 · Cited by 773 · see citing works

Chromatin Remodeling Is a Key Mechanism Underlying Cocaine-Induced Plasticity in Striatum

Kumar, A., Choi, K.-H., Renthal, W., Tsankova, N. M., Theobald, D. E. H., Truong, H.-T., Russo, S. J., LaPlant, Q., Sasaki, T. S., Whistler, K. N., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.023 · Cited by 764 · see citing works

Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine

Robinson, T. E., & Kolb, B. E. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00576.x · Cited by 726 · see citing works

WAVE, a novel WASP‐family protein involved in actin reorganization induced by Rac

Miki, H., Suetsugu, S., & Takenawa, T. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6932 · Cited by 709 · see citing works

Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine

Robinson, T. E., & Kolb, B. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08491.1997 · Cited by 704 · see citing works

Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum

Belin, D., & Everitt, B. J. (2008) · Neuron · doi:10.1016/j.neuron.2007.12.019 · Cited by 697 · see citing works

Development of long-term dendritic spine stability in diverse regions of cerebral cortex

Zuo, Y., Lin, A., Chang, P., & Gan, W.-B. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.001 · Cited by 684 · see citing works

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

Maze, I., Covington, H. E., Dietz, D. M., LaPlant, Q., Renthal, W., Russo, S. J., Mechanic, M., Mouzon, E., Neve, R. L., Haggarty, S. J., et al. (2010) · Science · doi:10.1126/science.1179438 · Cited by 665 · see citing works

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

Miki, H., Sasaki, T., Takai, Y., & Takenawa, T. (1998) · Nature · doi:10.1038/34208 · Cited by 644 · see citing works

Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine

Thomas, M. J., Beurrier, C., Bonci, A., & Malenka, R. C. (2001) · Nature Neuroscience · doi:10.1038/nn757 · Cited by 629 · see citing works

Regulation of gene expression and cocaine reward by CREB and ΔFosB

McClung, C. A., & Nestler, E. J. (2003) · Nature Neuroscience · doi:10.1038/nn1143 · Cited by 625 · see citing works

Molecular mechanisms of dendritic spine morphogenesis

Tada, T., & Sheng, M. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.12.001 · Cited by 615 · see citing works

Bidirectional Activity-Dependent Morphological Plasticity in Hippocampal Neurons

Nägerl, U. V., Eberhorn, N., Cambridge, S. B., & Bonhoeffer, T. (2004) · Neuron · doi:10.1016/j.neuron.2004.11.016 · Cited by 602 · see citing works

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments

Hope, B. T., Nye, H. E., Kelz, M. B., Self, D. W., Iadarola, M. J., Nakabeppu, Y., Duman, R. S., & Nestler, E. J. (1994) · Neuron · doi:10.1016/0896-6273(94)90061-2 · Cited by 563 · see citing works

Behavioral Sensitization to Cocaine Is Associated with Increased AMPA Receptor Surface Expression in the Nucleus Accumbens

Boudreau, A. C., & Wolf, M. E. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2252-05.2005 · Cited by 481 · see citing works

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5

Bibb, J. A., Chen, J., Taylor, J. R., Svenningsson, P., Nishi, A., Snyder, G. L., Yan, Z., Sagawa, Z. K., Ouimet, C. C., Nairn, A. C., et al. (2001) · Nature · doi:10.1038/35066591 · Cited by 480 · see citing works

Rapid Induction of Dendritic Spine Morphogenesis by trans-Synaptic EphrinB-EphB Receptor Activation of the Rho-GEF Kalirin

Penzes, P., Beeser, A., Chernoff, J., Schiller, M. R., Eipper, B. A., Mains, R. E., & Huganir, R. L. (2003) · Neuron · doi:10.1016/s0896-6273(02)01168-6 · Cited by 466 · see citing works

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF

Farnsworth, C. L., Freshney, N. W., Rosen, L. B., Ghosh, A., Greenberg, M. E., & Feig, L. A. (1995) · Nature · doi:10.1038/376524a0 · Cited by 434 · see citing works

The NMDA Receptor Is Coupled to the ERK Pathway by a Direct Interaction between NR2B and RasGRF1

Krapivinsky, G. B., Krapivinsky, L., Manasian, Y., Ivanov, A., Tyzio, R., Pellegrino, C., Ben‐Ari, Y., Clapham, D. E., & Medina, I. (2003) · Neuron · doi:10.1016/s0896-6273(03)00645-7 · Cited by 431 · see citing works

Cocaine Experience Controls Bidirectional Synaptic Plasticity in the Nucleus Accumbens

Kourrich, S., Rothwell, P. E., Klug, J. R., & Thomas, M. J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1859-07.2007 · Cited by 429 · see citing works

Molecular mechanisms of drug addiction [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]

Nestler, E. J. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-07-02439.1992 · Cited by 420 · see citing works

Transforming Growth Factor-β–induced Mobilization of Actin Cytoskeleton Requires Signaling by Small GTPases Cdc42 and RhoA

Edlund, S., Landström, M., Heldin, C., & Aspenström, P. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-08-0398 · Cited by 418 · see citing works

Genome-wide Analysis of Chromatin Regulation by Cocaine Reveals a Role for Sirtuins

Renthal, W., Kumar, A., Xiao, G., Wilkinson, M., Covington, H. E., Maze, I., Sikder, D., Robison, A. J., LaPlant, Q., Dietz, D. M., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.03.026 · Cited by 409 · see citing works

Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse

Graham, D. L., Edwards, S., Bachtell, R. K., Dileone, R., Rios, M., & Self, D. W. (2007) · Nature Neuroscience · doi:10.1038/nn1929 · Cited by 401 · see citing works

Transcriptional mechanisms of addiction: role of ΔFosB

Nestler, E. J. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0067 · Cited by 392 · see citing works

Identification of PSD-95 as a Regulator of Dopamine-Mediated Synaptic and Behavioral Plasticity

Yao, W., Gainetdinov, R. R., Arbuckle, M. I., Sotnikova, T. D., Cyr, M., Beaulieu, J., Torres, G. E., Grant, S. G. N., & Caron, M. G. (2004) · Neuron · doi:10.1016/s0896-6273(04)00048-0 · Cited by 380 · see citing works

The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines

Tolias, K. F., Bikoff, J. B., Burette, A., Paradis, S., Harrar, D., Tavazoie, S., Weinberg, R. J., & Greenberg, M. E. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.024 · Cited by 365 · see citing works

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

Bateup, H. S., Santini, E., Shen, W., Birnbaum, S. G., Valjent, E., Surmeier, D., Fisone, G., Nestler, E. J., & Greengard, P. (2010) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1009874107 · Cited by 361 · see citing works

Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens

Lee, K.-W., Kim, Y. D., Kim, A. M., Helmin, K. A., Nairn, A. C., & Greengard, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511244103 · Cited by 354 · see citing works

Spine architecture and synaptic plasticity

Carlisle, H. J., & Kennedy, M. B. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.01.008 · Cited by 351 · see citing works

Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology

Kim, Y., Sung, J. Y., Ceglia, I., Lee, K.-W., Ahn, J.-H., Halford, J. M., Kim, A. M., Kwak, S. P., Park, J. B., Ho Ryu, S., et al. (2006) · Nature · doi:10.1038/nature04976 · Cited by 307 · see citing works

Signalling and crosstalk of Rho GTPases in mediating axon guidance

Yuan, X., Jin, M., Xu, X., Song, Y., Wu, C.-P., Poo, M., & Duan, S. (2002) · Nature Cell Biology · doi:10.1038/ncb895 · Cited by 302 · see citing works

CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking

Anderson, S. M., Famous, K. R., Sadri-Vakili, G., Kumaresan, V., Schmidt, H. D., Bass, C. E., Terwilliger, E. F., Cha, J.-H. J., & Pierce, R. C. (2008) · Nature Neuroscience · doi:10.1038/nn2054 · Cited by 295 · see citing works

Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein

Murphy, D. D., & Segal, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1482 · Cited by 292 · see citing works

In Vivo Cocaine Experience Generates Silent Synapses

Huang, Y. H., Lin, Y., Mu, P., Lee, B. R., Brown, T. E., Wayman, G. A., Marie, H., Liu, W., Yan, Z., Sorg, B. A., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.06.007 · Cited by 290 · see citing works

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

Pulipparacharuvil, S., Renthal, W., Hale, C. F., Taniguchi, M., Xiao, G., Kumar, A., Russo, S. J., Sikder, D., Dewey, C. M., Davis, M. M., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.020 · Cited by 281 · see citing works

Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons.

Sklair‐Tavron, L., Shi, W. X., Lane, S. B., Harris, H. W., Bunney, B. S., & Nestler, E. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.11202 · Cited by 278 · see citing works

Cell Surface AMPA Receptors in the Rat Nucleus Accumbens Increase during Cocaine Withdrawal But Internalize after Cocaine Challenge in Association with Altered Activation of Mitogen-Activated Protein Kinases

Boudreau, A. C., Reimers, J. M., Milovanovic, M., & Wolf, M. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2163-07.2007 · Cited by 277 · see citing works

Neurotrophic factors and structural plasticity in addiction

Russo, S. J., Mazei‐Robison, M. S., Ables, J. L., & Nestler, E. J. (2008) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.06.059 · Cited by 271 · see citing works

An essential role for ΔFosB in the nucleus accumbens in morphine action

Zachariou, V., Bolaños, C. A., Selley, D. E., Theobald, D. E. H., Cassidy, M. P., Kelz, M. B., Shaw-Lutchman, T., Berton, O., Sim‐Selley, L. J., Dileone, R., et al. (2006) · Nature Neuroscience · doi:10.1038/nn1636 · Cited by 266 · see citing works

Vav2 Is an Activator of Cdc42, Rac1, and RhoA

Abe, K., Rossman, K. L., Liu, B., Ritola, K., Chiang, D. Y., Campbell, S. L., Burridge, K., & Der, C. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.14.10141 · Cited by 262 · see citing works

Destabilization of the Postsynaptic Density by PSD-95 Serine 73 Phosphorylation Inhibits Spine Growth and Synaptic Plasticity

Steiner, P., Higley, M. J., Xu, W., Czervionke, B. L., Malenka, R. C., & Sabatini, B. L. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.014 · Cited by 259 · see citing works

Nuclear Factor κB Signaling Regulates Neuronal Morphology and Cocaine Reward

Russo, S. J., Wilkinson, M. B., Mazei‐Robison, M. S., Dietz, D., Maze, I. S., Krishnan, V., Renthal, W. R., Graham, A., Birnbaum, S. G., Green, T. A., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.6173-08.2009 · Cited by 248 · see citing works

The sequence of events that underlie quantal transmission at central glutamatergic synapses

Lisman, J. E., Raghavachari, S., & Tsien, R. W. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2191 · Cited by 244 · see citing works

Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5

Norrholm, S. D., Bibb, J. A., Nestler, E. J., Ouimet, C. C., Taylor, J. R., & Greengard, P. (2003) · Neuroscience · doi:10.1016/s0306-4522(02)00560-2 · Cited by 238 · see citing works

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

Bateup, H. S., Svenningsson, P., Kuroiwa, M., Gong, S., Nishi, A., Heintz, N., & Greengard, P. (2008) · Nature Neuroscience · doi:10.1038/nn.2153 · Cited by 233 · see citing works

Widespread but regionally specific effects of experimenter‐ versus self‐administered morphine on dendritic spines in the nucleus accumbens, hippocampus, and neocortex of adult rats

Robinson, T. E., Gorny, G., Savage, V. R., & Kolb, B. E. (2002) · Synapse · doi:10.1002/syn.10146 · Cited by 224 · see citing works

Differential trafficking of AMPA and NMDA receptors by SAP102 and PSD-95 underlies synapse development

Elias, G. M., Elias, L. A. B., Apostolides, P. F., Kriegstein, A. R., & Nicoll, R. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811025106 · Cited by 223 · see citing works

Generation of Silent Synapses by Acute In Vivo Expression of CaMKIV and CREB

Marie, H., Morishita, W., Yu, X., Calakos, N., & Malenka, R. C. (2005) · Neuron · doi:10.1016/j.neuron.2005.01.039 · Cited by 219 · see citing works

IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates

Russo, S. J., Bolaños, C. A., Theobald, D. E. H., DeCarolis, N. A., Renthal, W. R., Kumar, A., Winstanley, C. A., Renthal, N. E., Wiley, M. D., Self, D. W., et al. (2006) · Nature Neuroscience · doi:10.1038/nn1812 · Cited by 215 · see citing works

Altered Dendritic Spine Plasticity in Cocaine-Withdrawn Rats

Shen, H., Toda, S., Moussawi, K., Bouknight, A., Zahm, D. S., & Kalivas, P. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5638-08.2009 · Cited by 213 · see citing works

Distinct patterns of ΔFosB induction in brain by drugs of abuse

Perrotti, L. I., Weaver, R. R., Robison, B., Renthal, W. R., Maze, I. S., Yazdani, S., Elmore, R. G., Knapp, D. J., Selley, D. E., Martin, B. R., et al. (2008) · Synapse · doi:10.1002/syn.20500 · Cited by 213 · see citing works

Regional and Cellular Mapping of cAMP Response Element-Mediated Transcription during Naltrexone-Precipitated Morphine Withdrawal

Shaw-Lutchman, T. Z., Barrot, M., Wallace, T. L., Gilden, L., Zachariou, V., Impey, S., Duman, R. S., Storm, D. R., & Nestler, E. J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03663.2002 · Cited by 205 · see citing works

Induction of Spine Growth and Synapse Formation by Regulation of the Spine Actin Cytoskeleton

Zito, K., Knott, G. W., Shepherd, G. M., Shenolikar, S., & Svoboda, K. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.022 · Cited by 192 · see citing works

Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking

Ambroggi, F., Turiault, M., Milet, A., Deroche‐Gamonet, V., Parnaudeau, S., Balado, É., Barik, J., van der Veen, R., Maroteaux, G., Lemberger, T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2282 · Cited by 182 · see citing works

The induction of behavioural sensitization is associated with cocaine‐induced structural plasticity in the core (but not shell) of the nucleus accumbens

Li, Y., Acerbo, M. J., & Robinson, T. E. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03612.x · Cited by 180 · see citing works

Cocaine Increases Actin Cycling: Effects in the Reinstatement Model of Drug Seeking

Toda, S., Shen, H., Peters, J., Cagle, S., & Kalivas, P. W. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4132-05.2006 · Cited by 147 · see citing works

Two-color, two-photon uncaging of glutamate and GABA

Kantevari, S., Matsuzaki, M., Kanemoto, Y., Kasai, H., & Ellis‐Davies, G. C. R. (2009) · Nature Methods · doi:10.1038/nmeth.1413 · Cited by 139 · see citing works

BDNF-dependent synaptic sensitization in midbrain dopamine neurons after cocaine withdrawal

Pu, L., Liu, Q.-S., & Poo, M. (2006) · Nature Neuroscience · doi:10.1038/nn1687 · Cited by 133 · see citing works

A Single Intra-PFC Infusion of BDNF Prevents Cocaine-Induced Alterations in Extracellular Glutamate within the Nucleus Accumbens

Berglind, W. J., Whitfield, T. W., LaLumiere, R. T., Kalivas, P. W., & McGinty, J. F. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5457-08.2009 · Cited by 131 · see citing works

Distinct Behavioral Responses to Ethanol Are Regulated by Alternate RhoGAP18B Isoforms

Rothenfluh, A., Threlkeld, R. J., Bainton, R. J., Tsai, L. T.-Y., Lasek, A. W., & Heberlein, U. (2006) · Cell · doi:10.1016/j.cell.2006.09.010 · Cited by 121 · see citing works

Methylphenidate-induced dendritic spine formation and ΔFosB expression in nucleus accumbens

Kim, Y. D., Teylan, M., Baron, M. L., Sands, A., Nairn, A. C., & Greengard, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813179106 · Cited by 120 · see citing works

WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines

Sung, J. Y., Engmann, O., Teylan, M. A., Nairn, A. C., Greengard, P., & Kim, Y. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712180105 · Cited by 117 · see citing works

Glutamate Signaling to Ras-MAPK in Striatal Neurons: Mechanisms for Inducible Gene Expression and Plasticity

Wang, J. Q., Tang, Q., Parelkar, N. K., Liu, Z., Samdani, S., Choe, E. S., Yang, L., & Mao, L. (2004) · Molecular Neurobiology · doi:10.1385/mn:29:1:01 · Cited by 112 · see citing works

Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine

Fasano, S., D'Antoni, A., Orban, P. C., Valjent, E., Putignano, E., Vara, H., Pizzorusso, T., Giustetto, M., Yoon, B.-J., Soloway, P. D., et al. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.03.014 · Cited by 107 · see citing works

Postnatal binge‐like alcohol exposure decreases dendritic complexity while increasing the density of mature spines in mPFC Layer II/III pyramidal neurons

Hamilton, G. F., Whitcher, L. T., & Klintsova, A. Y. (2009) · Synapse · doi:10.1002/syn.20711 · Cited by 98 · see citing works

Cdk5 Modulates Cocaine Reward, Motivation, and Striatal Neuron Excitability

Benavides, D. R., Quinn, J. J., Zhong, P., Hawasli, A. H., Dileone, R., Kansy, J. W., Olausson, P., Yan, Z., Taylor, J. R., & Bibb, J. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4061-07.2007 · Cited by 97 · see citing works

Acute cocaine exposure alters spine density and long‐term potentiation in the ventral tegmental area

Sarti, F., Borgland, S. L., Kharazia, V., & Bonci, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05689.x · Cited by 93 · see citing works

Regulation of CRE‐mediated transcription in mouse brain by amphetamine

Shaw‐Lutchman, T. Z., Impey, S., Storm, D. R., & Nestler, E. J. (2003) · Synapse · doi:10.1002/syn.10172 · Cited by 92 · see citing works

Homer Isoforms Differentially Regulate Cocaine-Induced Neuroplasticity

Szumlinski, K. K., Abernathy, K., Oleson, E. B., Klugmann, M., Lominac, K. D., He, D., Dorit Ron, A., During, M. J., & Kalivas, P. W. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300890 · Cited by 86 · see citing works

Regulation of fosB and ΔfosB mRNA expression: In vivo and in vitro studies

Alibhai, I. N., Green, T. A., Potashkin, J. A., & Nestler, E. J. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.069 · Cited by 80 · see citing works

Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine‐seeking behavior

Bachtell, R. K., Choi, K., Simmons, D. L., Falcón, E., Monteggia, L. M., Neve, R. L., & Self, D. W. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06199.x · Cited by 77 · see citing works

Molecular Mechanisms of Psychostimulant-induced Structural Plasticity

Dietz, D., Dietz, K. C., Nestler, E. J., & Russo, S. J. (2009) · Pharmacopsychiatry · doi:10.1055/s-0029-1202847 · Cited by 76 · see citing works

Morphine exposure and abstinence define specific stages of gene expression in the rat nucleus accumbens

Spijker, S., Houtzager, S. W. J., de Gunst, M. C. M., de Boer, W. P. H., Schoffelmeer, A. N. M., & Smit, A. B. (2004) · The FASEB Journal · doi:10.1096/fj.03-0612fje · Cited by 72 · see citing works

Cocaine-evoked synaptic plasticity: a key to addiction?

Lüscher, C., & Bellone, C. (2008) · Nature Neuroscience · doi:10.1038/nn0708-737 · Cited by 45 · see citing works

Cocaine regulates ezrin–radixin–moesin proteins and RhoA signaling in the nucleus accumbens

Kim, W. Y., Shin, S., Kim, S., Jeon, S., & Kim, J. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.06.067 · Cited by 34 · see citing works

Opposing functions of CREB and MKK1 synergistically regulate the geometry of dendritic spines in visual cortex

Suzuki, S., Zhou, H., Neumaier, J. F., & Pham, T. A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21424 · Cited by 21 · see citing works

The expanding role of PSD-95: a new link to addiction

Roche, K. W. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.09.002 · Cited by 18 · see citing works

Addition of a 5-HT receptor agonist to methylphenidate potentiates the reduction of [123I]FP-CIT binding to dopamine transporters in rat frontal cortex and hippocampus

Reneman, L., de Bruin, K. M., Lavalaye, J., Gunning, W. B., & Booij, J. (2001) · Synapse · doi:10.1002/1098-2396(20010301)39:3 · Cited by 16 · see citing works

The brain on drugs: from reward to addiction

Volkow, N. D., & Morales, M. (2015) · Cell · doi:10.1016/j.cell.2015.07.046 · Cited by 1,306 · see citing works

Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling

Lüscher, C., & Malenka, R. C. (2011) · Neuron · doi:10.1016/j.neuron.2011.01.017 · Cited by 1,105 · see citing works

Transcriptional and epigenetic mechanisms of addiction

Robison, A. J., & Nestler, E. J. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3111 · Cited by 993 · see citing works

Social influences on neuroplasticity: stress and interventions to promote well-being

Davidson, R. J., & McEwen, B. S. (2012) · Nature Neuroscience · doi:10.1038/nn.3093 · Cited by 892 · see citing works

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

LaPlant, Q., Vialou, V., Covington, H. E., Dumitriu, D., Feng, J., Warren, B. L., Maze, I., Dietz, D. M., Watts, E. L., Iñiguez, S. D., et al. (2010) · Nature Neuroscience · doi:10.1038/nn.2619 · Cited by 612 · see citing works

The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis

Scofield, M. D., Heinsbroek, J. A., Gipson, C. D., Kupchik, Y. M., Spencer, S., Smith, A. C. W., Roberts-Wolfe, D., & Kalivas, P. W. (2016) · Pharmacological Reviews · doi:10.1124/pr.116.012484 · Cited by 598 · see citing works

Basal Ganglia Disorders Associated with Imbalances in the Striatal Striosome and Matrix Compartments

Crittenden, J. R., & Graybiel, A. M. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00059 · Cited by 470 · see citing works

Opiate versus psychostimulant addiction: the differences do matter

Badiani, A., Belin, D., Epstein, D. H., Calu, D. J., & Shaham, Y. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3104 · Cited by 466 · see citing works

Epigenetic mechanisms of drug addiction

Nestler, E. J. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.004 · Cited by 458 · see citing works

The dark side of emotion: the addiction perspective

Koob, G. F. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.11.044 · Cited by 433 · see citing works

The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons

Lobo, M. K., & Nestler, E. J. (2011) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2011.00041 · Cited by 371 · see citing works

Nuclear calcium signalling in the regulation of brain function

Bading, H. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3531 · Cited by 374 · see citing works

Psychedelics reopen the social reward learning critical period

Nardou, R., Sawyer, E., Song, Y. J., Wilkinson, M., Padovan-Hernandez, Y., de Deus, J. L., Wright, N., Lama, C., Faltin, S., Goff, L. A., et al. (2023) · Nature · doi:10.1038/s41586-023-06204-3 · Cited by 358 · see citing works

One Is Not Enough: Understanding and Modeling Polysubstance Use

Crummy, E. A., O’Neal, T. J., Baskin, B. M., & Ferguson, S. M. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00569 · Cited by 351 · see citing works

New medications for drug addiction hiding in glutamatergic neuroplasticity

Kalivas, P. W., & Volkow, N. D. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.46 · Cited by 342 · see citing works

Natural rewards, neuroplasticity, and non-drug addictions

Olsen, C. M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.03.010 · Cited by 339 · see citing works

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

Calipari, E. S., Bagot, R. C., Purushothaman, I., Davidson, T. J., Yorgason, J. T., Peña, C. J., Walker, D. M., Pirpinias, S. T., Guise, K. G., Ramakrishnan, C., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521238113 · Cited by 317 · see citing works

Structural and synaptic plasticity in stress-related disorders

Christoffel, D. J., Golden, S. A., & Russo, S. J. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.044 · Cited by 334 · see citing works

Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories – indications for novel treatments of addiction

Everitt, B. J. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12644 · Cited by 318 · see citing works

Addiction and Stress: An Allostatic View

Koob, G. F., & Schulkin, J. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.008 · Cited by 315 · see citing works

The neurobiology of food intake in an obesogenic environment

Berthoud, H. (2012) · Proceedings of The Nutrition Society · doi:10.1017/s0029665112000602 · Cited by 305 · see citing works

Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings

Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299 · see citing works

Striatal Circuits as a Common Node for Autism Pathophysiology

Fuccillo, M. V. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00027 · Cited by 269 · see citing works

Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

Lee, B. R., Ma, Y., Huang, Y. H., Wang, X., Otaka, M., Ishikawa, M., Neumann, P. A., Graziane, N., Brown, T. E., Beroun, A., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3533 · Cited by 297 · see citing works

The hippocampal-striatal axis in learning, prediction and goal-directed behavior

Pennartz, C. M. A., Ito, R., Verschure, P. F. M. J., Battaglia, F. P., & Robbins, T. W. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.08.001 · Cited by 287 · see citing works

Synaptic circuit remodelling by matrix metalloproteinases in health and disease

Huntley, G. W. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3320 · Cited by 282 · see citing works

Stress, anxiety, and dendritic spines: What are the connections?

Leuner, B., & Shors, T. J. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2012.04.021 · Cited by 284 · see citing works

Food reward, hyperphagia, and obesity

Berthoud, H.-R., Lenard, N. R., & Shin, A. C. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00028.2011 · Cited by 275 · see citing works

Neural mechanisms of aggression across species

Lischinsky, J. E., & Lin, D. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00715-2 · Cited by 267 · see citing works

IκB Kinase Regulates Social Defeat Stress-Induced Synaptic and Behavioral Plasticity

Christoffel, D. J., Golden, S. A., Dumitriu, D., Robison, A. J., Janssen, W. G., Ahn, H. F., Krishnan, V., Reyes, C. M., Han, M.-H., Ables, J. L., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4763-10.2011 · Cited by 267 · see citing works

Reward Circuitry in Addiction

Cooper, S., Robison, A. J., & Mazei‐Robison, M. S. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0525-z · Cited by 264 · see citing works

Cellular basis of memory for addiction

Nestler, E. J. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/enestler · Cited by 259 · see citing works

Reward and aversion

Hu, H. (2016) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070815-014106 · Cited by 253 · see citing works

The dopamine hypothesis of drug addiction and its potential therapeutic value

Diana, M. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00064 · Cited by 251 · see citing works

New technologies for examining the role of neuronal ensembles in drug addiction and fear

Cruz, F. C., Koya, E., Guez‐Barber, D., Bossert, J. M., Lupica, C. R., Shaham, Y., & Hope, B. T. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3597 · Cited by 241 · see citing works

The neurobiology of addiction

Uhl, G. R., Koob, G. F., & Cable, J. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13989 · Cited by 259 · see citing works

The Bermuda Triangle of cocaine-induced neuroadaptations

Wolf, M. E. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.06.003 · Cited by 228 · see citing works

A multistep general theory of transition to addiction

Piazza, P. V., & Deroche-Gamonet, V. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3224-4 · Cited by 227 · see citing works

Chapter 1. Neurocircuitry of Addiction

Koob, G. F., & Volkow, N. D. (2021) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615373970.kb01 · Cited by 236 · see citing works

Deep brain stimulation in addiction: a review of potential brain targets

Luigjes, J., van den Brink, W., Feenstra, M. G. P., van den Munckhof, P., Schuurman, P. R., Schippers, R., Mazaheri, A., Vries, T. J. D., & Denys, D. A. J. P. (2011) · Molecular Psychiatry · doi:10.1038/mp.2011.114 · Cited by 222 · see citing works

Food addiction: a valid concept?

Fletcher, P. C., & Kenny, P. J. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0203-9 · Cited by 224 · see citing works

Improving translation of animal models of addiction and relapse by reverse translation

Venniro, M., Banks, M. L., Heilig, M., Epstein, D. H., & Shaham, Y. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0378-z · Cited by 212 · see citing works

Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why?

Wolf, M. E., & Tseng, K. Y. (2012) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2012.00072 · Cited by 199 · see citing works

FosB differentially modulates nucleus accumbens direct and indirect pathway function

Grueter, B. A., Robison, A. J., Neve, R. L., Nestler, E. J., & Malenka, R. C. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1221742110 · Cited by 191 · see citing works

Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity

Kreple, C. J., Lü, Y., Taugher, R. J., Gutman, A. L., Du, J., Stump, M., Wang, Y., Ghobbeh, A., Fan, R., Cosme, C. V., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3750 · Cited by 195 · see citing works

Up-Regulation of MicroRNAs in Brain of Human Alcoholics

Lewohl, J. M., Núnez, Y. O., Dodd, P. R., Tiwari, G. R., Harris, R. A., & Mayfield, R. D. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01544.x · Cited by 192 · see citing works

Structural and functional plasticity of dendritic spines – root or result of behavior?

Gipson, C. D., & Olive, M. F. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12324 · Cited by 192 · see citing works

Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell

Robison, A. J., Vialou, V., Mazei-Robison, M., Feng, J., Kourrich, S., Collins, M., Wee, S., Koob, G., Turecki, G., Neve, R., et al. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.5192-12.2013 · Cited by 190 · see citing works

BDNF is a negative modulator of morphine action

Koo, J. W., Mazei-Robison, M. S., Chaudhury, D., Juarez, B., LaPlant, Q., Ferguson, D., Feng, J., Sun, H., Scobie, K. N., Damez-Werno, D., et al. (2012) · Science · doi:10.1126/science.1222265 · Cited by 189 · see citing works

A pivotal role of GSK-3 in synaptic plasticity

Bradley, C. A., Peineau, S., Taghibiglou, C., Nicolas, C. S., Whitcomb, D. J., Bortolotto, Z. A., Kaang, B., Cho, K., Wang, Y. T., & Collingridge, G. L. (2012) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2012.00013 · Cited by 189 · see citing works

Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons

Dietz, D., Sun, H., Lobo, M. K., Cahill, M. E., Chadwick, B. J., Gao, V., Koo, J. W., Mazei‐Robison, M. S., Dias, C., Maze, I. S., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3094 · Cited by 181 · see citing works

Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products

England, L. J., Aagaard, K., Bloch, M., Conway, K., Cosgrove, K., Grana, R., Gould, T. J., Hatsukami, D., Jensen, F., Kandel, D., et al. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.11.013 · Cited by 181 · see citing works

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms

Fuccillo, M. V., Földy, C., Gökçe, Ö., Rothwell, P. E., Sun, G. L., Malenka, R. C., & Südhof, T. C. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.028 · Cited by 173 · see citing works

Hippocampus, amygdala, and stress: interacting systems that affect susceptibility to addiction

Belujon, P., & Grace, A. A. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05896.x · Cited by 171 · see citing works

Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction

Cruz, F. C., Rubio, F. J., & Hope, B. T. (2014) · Brain Research · doi:10.1016/j.brainres.2014.11.005 · Cited by 162 · see citing works

Nucleus Accumbens Modulation in Reward and Aversion

Klawonn, A. M., & Malenka, R. C. (2018) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2018.83.037457 · Cited by 163 · see citing works

The neural rejuvenation hypothesis of cocaine addiction

Dong, Y., & Nestler, E. J. (2014) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2014.05.005 · Cited by 163 · see citing works

Cocaine exposure reorganizes cell type– and input-specific connectivity in the nucleus accumbens

MacAskill, A. F., Cassel, J. M., & Carter, A. G. (2014) · Nature Neuroscience · doi:10.1038/nn.3783 · Cited by 155 · see citing works

Deep Brain Stimulation for Psychiatric Disease: Contributions and Validity of Animal Models

Hamani, C., & Temel, Y. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003722 · Cited by 157 · see citing works

Transcriptional Mechanisms of Drug Addiction

Nestler, E. J. (2012) · Clinical Psychopharmacology and Neuroscience · doi:10.9758/cpn.2012.10.3.136 · Cited by 156 · see citing works

Cell-Type-Specific Afferent Innervation of the Nucleus Accumbens Core and Shell

Li, Z., Chen, Z., Fan, G., Li, A., Yuan, J., & Xu, T. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00084 · Cited by 155 · see citing works

High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy

Dumitriu, D., Rodriguez, A., & Morrison, J. H. (2011) · Nature Protocols · doi:10.1038/nprot.2011.389 · Cited by 153 · see citing works

Dopamine and addiction: what have we learned from 40 years of research

Solinas, M., Belujon, P., Fernagut, P., Jaber, M., & Thiriet, N. (2018) · Journal of Neural Transmission · doi:10.1007/s00702-018-1957-2 · Cited by 155 · see citing works

The evolving role of dendritic spines and memory: Interaction(s) with estradiol

Frankfurt, M., & Luine, V. N. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.05.004 · Cited by 148 · see citing works

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works

Rapid, transient synaptic plasticity in addiction

Gipson, C. D., Kupchik, Y. M., & Kalivas, P. W. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.032 · Cited by 145 · see citing works

Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology

Lippi, G., Steinert, J. R., Marczylo, E. L., D’Oro, S., Fiore, R., Forsythe, I. D., Schratt, G. M., Zoli, M., Nicotera, P., & Young, K. W. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201103006 · Cited by 145 · see citing works

Stress during development alters dendritic morphology in the nucleus accumbens and prefrontal cortex

Muhammad, A., Carroll, C., & Kolb, B. E. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.04.041 · Cited by 146 · see citing works

Neuronal Correlates of Depression

Chaudhury, D., Liu, H., & Han, M.-H. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2044-6 · Cited by 139 · see citing works

Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems

Rutherford, H. J. V., Williams, S. K., Moy, S., Mayes, L. C., & Johns, J. M. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00037 · Cited by 140 · see citing works

Integrating synaptic plasticity and striatal circuit function in addiction

Grueter, B. A., Rothwell, P. E., & Malenka, R. C. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.09.009 · Cited by 139 · see citing works

Essential Role of SIRT1 Signaling in the Nucleus Accumbens in Cocaine and Morphine Action

Ferguson, D., Koo, J. W., Feng, J., Heller, E. A., Rabkin, J., Heshmati, M., Renthal, W. R., Neve, R. L., Liu, X., Shao, N., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.1284-13.2013 · Cited by 139 · see citing works

Cell Type-Specific Alterations in the Nucleus Accumbens by Repeated Exposures to Cocaine

Kim, J., Park, B.-H., Lee, J. H., Park, S. K., & Kim, J. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.01.013 · Cited by 134 · see citing works

Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

Miller, M. L., Chadwick, B., Dickstein, D. L., Purushothaman, I., Egervari, G., Rahman, T., Tessereau, C., Hof, P. R., Roussos, P., Shen, L., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-018-0243-x · Cited by 134 · see citing works

Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases

Smith, A. C. W., Kupchik, Y. M., Scofield, M. D., Gipson, C. D., Wiggins, A., Thomas, C. A., & Kalivas, P. W. (2014) · Nature Neuroscience · doi:10.1038/nn.3846 · Cited by 133 · see citing works

Opposing Role for Egr3 in Nucleus Accumbens Cell Subtypes in Cocaine Action

Chandra, R., Francis, T. C., Konkalmatt, P. R., Amgalan, A., Gancarz, A. M., Dietz, D., & Lobo, M. K. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0548-15.2015 · Cited by 124 · see citing works

From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms

Kabir, Z. D., Martínez-Rivera, A., & Rajadhyaksha, A. M. (2017) · Neurotherapeutics · doi:10.1007/s13311-017-0532-0 · Cited by 125 · see citing works

Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior

Stefanik, M. T., Kupchik, Y. M., & Kalivas, P. W. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-0997-8 · Cited by 123 · see citing works

mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse

Neasta, J., Barak, S., Hamida, S. B., & Ron, D. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12725 · Cited by 114 · see citing works

Born to learn: The inspiration, progress, and future of evolved plastic artificial neural networks

Soltoggio, A., Stanley, K. O., & Risi, S. (2018) · Neural Networks · doi:10.1016/j.neunet.2018.07.013 · Cited by 124 · see citing works

How Preclinical Models Evolved to Resemble the Diagnostic Criteria of Drug Addiction

Belin‐Rauscent, A., Fouyssac, M., Bonci, A., & Belin, D. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.01.004 · Cited by 118 · see citing works

Animal models for medications development targeting alcohol abuse using selectively bred rat lines: Neurobiological and pharmacological validity

Bell, R. L., Sable, H. J. K., Colombo, G., Hyytiä, P., Rodd, Z. A., & Lumeng, L. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.07.007 · Cited by 119 · see citing works

Opiate-Induced Molecular and Cellular Plasticity of Ventral Tegmental Area and Locus Coeruleus Catecholamine NeuronsPreprint

Mazei‐Robison, M. S., & Nestler, E. J. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a012070 · Cited by 113 · see citing works

Alcohol Elicits Functional and Structural Plasticity Selectively in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum

Wang, J., Cheng, Y., Wang, X., Roltsch, E. A., Ma, T., Gil, H., Hamida, S. B., & Dorit Ron, A. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0003-15.2015 · Cited by 112 · see citing works

The role of stress in drug addiction. An integrative review

Ruisoto, P., & Contador, I. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.01.022 · Cited by 119 · see citing works

Visualizing an emotional valence map in the limbic forebrain by TAI-FISH

Xiu, J., Zhang, Q., Zhou, T., Zhou, T.-T., Chen, Y., & Hu, H. (2014) · Nature Neuroscience · doi:10.1038/nn.3813 · Cited by 112 · see citing works

Levodopa-induced plasticity: a double-edged sword in Parkinson's disease?

Calabresi, P., Ghiglieri, V., Mazzocchetti, P., Corbelli, I., & Picconi, B. (2015) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0184 · Cited by 114 · see citing works

Estradiol mediates dendritic spine plasticity in the nucleus accumbens core through activation of mGluR5

Peterson, B. M., Mermelstein, P. G., & Meisel, R. L. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0794-9 · Cited by 108 · see citing works

Oxytocin in learning and addiction: From early discoveries to the present

Sarnyai, Z., & Kovács, G. L. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.11.019 · Cited by 106 · see citing works

Subregional, Dendritic Compartment, and Spine Subtype Specificity in Cocaine Regulation of Dendritic Spines in the Nucleus Accumbens

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Cui, C. (2006) · Zhongguo yaowu yilaixing zazhi

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www.elsevier.com/locate/neuropharm Structural plasticity associatedwith exposure to drugs of abuse

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