Kunkel, Thomas A.

DNA Replication Fidelity

Kunkel, T. A., & Bebenek, K. (2000) · Annual Review of Biochemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 1,003

The accuracy of reverse transcriptase from HIV-1

Roberts, J. D., Bebenek, K., & Kunkel, T. A. (1988) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 997

DNA Replication Fidelity

Kunkel, T. A. (2004) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 754

Fidelity of DNA Synthesis

Loeb, L. A., & Kunkel, T. A. (1982) · Annual Review of Biochemistry

DNA Repair MechanismsHippo pathway signaling and YAP/TAZ

Cited by 511

Biochemical Basis of DNA Replication Fidelity

Goodman, M. F., Creighton, S., Bloom, L. B., Petruska, J., & Kunkel, T. A. (1993) · Critical Reviews in Biochemistry and Molecular Biology

DNA and Nucleic Acid ChemistryDNA Repair Mechanisms

Cited by 446

Low fidelity DNA synthesis by human DNA polymerase-η

Matsuda, T., Bebenek, K., Masutani, C., Hanaoka, F., & Kunkel, T. A. (2000) · Nature

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 372

RNase H2-Initiated Ribonucleotide Excision Repair

Sparks, J. L., Chon, H., Cerritelli, S. M., Kunkel, T. A., Johansson, E., Crouch, R. J., & Burgers, P. M. (2012) · Molecular Cell

DNA Repair MechanismsFungal and yeast genetics research

Cited by 339

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

Jirawatnotai, S., Hu, Y., Michowski, W., Elias, J. E., Becks, L., Bienvenu, F., Zagozdzon, A., Goswami, T., Wang, Y. E., Clark, A. B., et al. (2011) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 333

Misalignment-mediated DNA synthesis errors

Kunkel, T. A. (1990) · Biochemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 299

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

Kunkel, T. A., & Alexander, P. S. (1986) · Journal of Biological Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 299

Somatic mutation hotspots correlate with DNA polymerase η error spectrum

Rogozin, I. B., Pavlov, Y. I., Bebenek, K., Matsuda, T., & Kunkel, T. A. (2001) · Nature Immunology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 298

Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I

Kim, N., Huang, S.-Y. N., Williams, J. S., Li, Y. C., Clark, A. B., Cho, J.-E., Kunkel, T. A., Pommier, Y., & Jinks-Robertson, S. (2011) · Science

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 291

The Fidelity of Human DNA Polymerase γ with and without Exonucleolytic Proofreading and the p55 Accessory Subunit

Longley, M. J., Nguyen, D., Kunkel, T. A., & Copeland, W. C. (2001) · Journal of Biological Chemistry

DNA Repair MechanismsMitochondrial Function and Pathology

Cited by 270

Functions of DNA polymerases

Bebenek, K., & Kunkel, T. A. (2004) · Advances in Protein Chemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 258

Preferential cis–syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity

McCulloch, S. D., Kokoska, R. J., Masutani, C., Iwai, S., Hanaoka, F., & Kunkel, T. A. (2004) · Nature

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 246

Fidelity of Two Retroviral Reverse Transcriptases during DNA-Dependent DNA Synthesis In Vitro

Roberts, J. D., Preston, B. D., Johnston, L. A., Soni, A., Loeb, L. A., & Kunkel, T. A. (1989) · Molecular and Cellular Biology

Evolution and Genetic DynamicsDNA and Nucleic Acid Chemistry

Cited by 189

Processing ribonucleotides incorporated during eukaryotic DNA replication

Williams, J. S., Lujan, S. A., & Kunkel, T. A. (2016) · Nature Reviews Molecular Cell Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 188

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

Clausen, A. R., Lujan, S. A., Burkholder, A. B., Orebaugh, C. D., Williams, J. S., Clausen, M. F., Malc, E. P., Mieczkowski, P. A., Fargo, D. C., Smith, D. J., et al. (2015) · Nature Structural & Molecular Biology

DNA Repair MechanismsFungal and yeast genetics research

Cited by 188

Error rate and specificity of human and murine DNA polymerase η

Matsuda, T., Bebenek, K., Masutani, C., Rogozin, I. B., Hanaoka, F., & Kunkel, T. A. (2001) · Journal of Molecular Biology

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 170

Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA

Williams, J. S., Smith, D. J., Marjavaara, L., Lujan, S. A., Chabes, A., & Kunkel, T. A. (2013) · Molecular Cell

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 157

Active Site Mutation in DNA Polymerase γ Associated with Progressive External Ophthalmoplegia Causes Error-prone DNA Synthesis

Ponamarev, M. V., Longley, M. J., Nguyen, D., Kunkel, T. A., & Copeland, W. C. (2002) · Journal of Biological Chemistry

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 156

Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates

Boyer, J. C., Bebenek, K., & Kunkel, T. A. (1992) · Proceedings of the National Academy of Sciences

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 142

DNA replication fidelity with 8-oxodeoxyguanosine triphosphate

Pavlov, Y. I., Minnick, D. T., Izuta, S., & Kunkel, T. A. (1994) · Biochemistry

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 132

Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ

Clausen, A. R., Zhang, S., Burgers, P. M., Lee, M. Y., & Kunkel, T. A. (2013) · DNA Repair

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 130