Ilonen, Jorma

Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

Ziegler, A. G., Rewers, M., Simell, O., Simell, T., Lempainen, J., Steck, A., Winkler, C., Ilonen, J., Veijola, R., Knip, M., et al. (2013) · JAMA

Diabetes and associated disordersDiabetes Management and Research

Cited by 1,312

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

Vatanen, T., Kostic, A. D., d’Hennezel, E., Siljander, H., Franzosa, E. A., Yassour, M., Kolde, R., Vlamakis, H., Arthur, T. D., Hämäläinen, A.-M., et al. (2016) · Cell

Gut microbiota and healthImmune Response and Inflammation

Cited by 1,289

Toward defining the autoimmune microbiome for type 1 diabetes

Giongo, A., Gano, K. A., Crabb, D. B., Mukherjee, N., Novelo, L. L., Casella, G., Drew, J. C., Ilonen, J., Knip, M., Hyöty, H., et al. (2011) · The ISME Journal

Gut microbiota and healthDiabetes and associated disorders

Cited by 806

Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes

Brown, C. T., Davis-Richardson, A. G., Giongo, A., Gano, K. A., Crabb, D. B., Mukherjee, N., Casella, G., Drew, J. C., Ilonen, J., Knip, M., et al. (2011) · PLoS ONE

Gut microbiota and healthDiabetes and associated disorders

Cited by 778

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life

Yassour, M., Jason, E., Hogstrom, L. J., Arthur, T. D., Tripathi, S., Siljander, H., Selvenius, J., Oikarinen, S., Hyöty, H., Virtanen, S. M., et al. (2018) · Cell Host & Microbe

Gut microbiota and healthInfant Nutrition and Health

Cited by 455

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

Orešič, M., Simell, S., Sysi-Aho, M., Näntö-Salonen, K., Seppänen-Laakso, T., Parikka, V., Katajamaa, M., Hekkala, A., Mattila, I., Keskinen, P., et al. (2008) · The Journal of Experimental Medicine

Diabetes and associated disordersMetabolomics and Mass Spectrometry Studies

Cited by 449

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

the TEDDY Study Group, Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J.-X., Simell, O. G., et al. (2015) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 444

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

Näntö-Salonen, K., Kupila, A., Simell, S., Siljander, H., Salonsaari, T., Hekkala, A., Korhonen, S., Erkkola, R., Sipilä, J. I., Haavisto, L., et al. (2008) · The Lancet

Diabetes and associated disordersDiabetes Management and Research

Cited by 382

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

Vatanen, T., Kostic, A. D., d’Hennezel, E., Siljander, H., Franzosa, E. A., Yassour, M., Kolde, R., Vlamakis, H., Arthur, T. D., Hämäläinen, A.-M., et al. (2016) · Cell

Gut microbiota and healthImmune Response and Inflammation

Cited by 298

Dietary intervention in infancy and later signs of beta-cell autoimmunity

Knip, M., Virtanen, S. M., Seppä, K., Ilonen, J., Savilahti, E., Vaarala, O., Reunanen, A., Teramo, K., Hämäläinen, A.-M., Paronen, J., et al. (2010) · New England Journal of Medicine

Diabetes and associated disordersInfant Nutrition and Health

Cited by 281

The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants

Hagopian, W. A., Erlich, H., Lernmark, Å., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Vogt, R., Blair, A., Ilonen, J., et al. (2011) · Pediatric Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 260

Temporal changes in the frequencies of HLA genotypes in patients with type 1 diabetes–indication of an increased environmental pressure?

the FinnDiane Study Group, Hermann, R., Knip, M., Veijola, R., Simell, O., Laine, A.-P., Åkerblom, H. K., Groop, P.-H., Forsblom, C., Pettersson-Fernholm, K., et al. (2003) · Diabetologia

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 245

Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk

Parikka, V., Näntö-Salonen, K., Saarinen, M., Simell, T., Ilonen, J., Hyöty, H., Veijola, R., Knip, M., & Simell, O. (2012) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 235

Genetic, autoimmune, and clinical characteristics of childhood- and adult-onset type 1 diabetes.

Sabbah, E., Savola, K., Ebeling, T., Kulmala, P., Vähäsalo, P., Ilonen, J., Salmela, P. I., & Knip, M. (2000) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 219

Cow's milk formula feeding induces primary immunization to insulin in infants at genetic risk for type 1 diabetes

Vaarala, O., Knip, M., Paronen, J., Hämäläinen, A. M., Muona, P., Väätäinen, M., Ilonen, J., Simell, O., & Akerblom, H. K. (1999) · Diabetes

Diabetes and associated disordersInfant Nutrition and Health

Cited by 182

Recombination in circulating enteroviruses

Lukashev, A. N., Lashkevich, V. A., Ivanova, O. E., Koroleva, G. A., Hinkkanen, A. E., & Ilonen, J. (2003) · Journal of Virology

Evolution and Genetic DynamicsViral Infections and Immunology Research

Cited by 170

Timing of infant feeding in relation to childhood asthma and allergic diseases

Nwaru, B. I., Takkinen, H.-M., Niemelä, O., Kaila, M., Erkkola, M., Ahonen, S., Haapala, A.-M., Kenward, M. G., Pekkanen, J., Lahesmaa, R., et al. (2013) · Journal of Allergy and Clinical Immunology

Asthma and respiratory diseasesFood Allergy and Anaphylaxis Research

Cited by 151

Natural History of β-Cell Autoimmunity in Young Children with Increased Genetic Susceptibility to Type 1 Diabetes Recruited from the General Population

Kimpimäki, T., Kulmala, P., Savola, K., Kupila, A., Korhonen, S., Simell, T., Ilonen, J., Simell, O., & Knip, M. (2002) · The Journal of Clinical Endocrinology & Metabolism

Diabetes and associated disordersDiabetes Management and Research

Cited by 146

Removal of Bovine Insulin From Cow's Milk Formula and Early Initiation of Beta-Cell Autoimmunity in the FINDIA Pilot Study

Vaarala, O., Ilonen, J., Ruohtula, T., Pesola, J., Virtanen, S. M., Härkönen, T., Koski, M., Kallioinen, H., Tossavainen, O., Poussa, T., et al. (2012) · Archives of Pediatrics & Adolescent Medicine

Diabetes and associated disordersInfant Nutrition and Health

Cited by 127

Dynamics of Diabetes-Associated Autoantibodies in Young Children with Human Leukocyte Antigen-Conferred Risk of Type 1 Diabetes Recruited from the General Population

Kukko, M., Kimpimäki, T., Korhonen, S., Kupila, A., Simell, S., Veijola, R., Simell, T., Ilonen, J., Simell, O., & Knip, M. (2005) · The Journal of Clinical Endocrinology & Metabolism

Diabetes and associated disordersDiabetes Management and Research

Cited by 116

Hierarchical order of distinct autoantibody spreading and progression to type 1 diabetes in the TEDDY study

Vehik, K., Bonifacio, E., Lernmark, Å., Yu, L., Williams, A., Schatz, D., Rewers, M., She, J.-X., Toppari, J., Hagopian, W., et al. (2020) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 87

Islet autoimmunity and HLA markers of presymptomatic and clinical type 1 diabetes: joint analyses of prospective cohort studies in Finland, Germany, Sweden, and the U.S

Anand, V., Li, Y., Liu, B., Ghalwash, M., Koski, E., Ng, K., Dunne, J. L., Jönsson, J., Winkler, C., Knip, M., et al. (2021) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 83

Early exposure to cats, dogs and farm animals and the risk of childhood asthma and allergy

Ojwang, V., Nwaru, B. I., Takkinen, H., Kaila, M., Niemelä, O., Haapala, A., Ilonen, J., Toppari, J., Hyöty, H., Veijola, R., et al. (2020) · Pediatric Allergy and Immunology

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 63

Human parechoviruses are frequently detected in stool of healthy Finnish children

Kolehmainen, P., Oikarinen, S., Koskiniemi, M., Simell, O., Ilonen, J., Knip, M., Hyöty, H., & Tauriainen, S. (2012) · Journal of Clinical Virology

Viral Infections and Immunology ResearchViral gastroenteritis research and epidemiology

Cited by 62