The cell biology of fat expansion

The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function

Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481 · see citing works

Increased oxidative stress in obesity and its impact on metabolic syndrome

Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508 · see citing works

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Wu, J., Boström, P., Sparks, L. M., Li, Y., Choi, J. H., Giang, A.-H., Khandekar, M. J., Virtanen, K. A., Nuutila, P., Schaart, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.05.016 · Cited by 3,299 · see citing works

Dynamics of fat cell turnover in humans

Spalding, K. L., Arner, E., Westermark, P. O., Bernard, S., Buchholz, B. A., Bergmann, O., Blomqvist, L., Hoffstedt, J., Näslund, E., Britton, T., et al. (2008) · Nature · doi:10.1038/nature06902 · Cited by 2,357 · see citing works

PRDM16 controls a brown fat/skeletal muscle switch

Seale, P., Bjork, B., Yang, W., Kajimura, S., Chin, S., Kuang, S., Scimè, A., Devarakonda, S., Conroe, H. M., Erdjument-Bromage, H., et al. (2008) · Nature · doi:10.1038/nature07182 · Cited by 2,347 · cited 2× · see citing works

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Koves, T. R., Ussher, J. R., Noland, R. C., Slentz, D., Mosedale, M., Ilkayeva, O., Bain, J., Stevens, R., Dyck, J. R. B., Newgard, C. B., et al. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.013 · Cited by 1,990 · see citing works

Adipose tissue remodeling and obesity

Sun, K., Kusminski, C. M., & Scherer, P. E. (2011) · Journal of Clinical Investigation · doi:10.1172/jci45887 · Cited by 1,941 · see citing works

Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease

Samuel, V. T., Liu, Z.-X., Qu, X., Elder, B. D., Bilz, S., Befroy, D., Romanelli, A. J., & Shulman, G. I. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313478200 · Cited by 1,322 · see citing works

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

Feldmann, H. M., Golozoubova, V., Cannon, B., & Nedergaard, J. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2008.12.014 · Cited by 1,318 · see citing works

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

Wang, Q. A., Tao, C., Gupta, R. K., & Scherer, P. E. (2013) · Nature Medicine · doi:10.1038/nm.3324 · Cited by 1,262 · see citing works

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Abel, E. D., Peroni, O. D., Kim, J. K., Kim, Y., Boss, O., Hadro, E., Minnemann, T., Shulman, G. I., & Kahn, B. B. (2001) · Nature · doi:10.1038/35055575 · Cited by 1,253 · see citing works

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Holland, W. L., Brozinick, J. T., Wang, L.-P., Hawkins, E. D., Sargent, K. M., Liu, Y., Narra, K., Hoehn, K. L., Knotts, T. A., Siesky, A., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.01.002 · Cited by 1,232 · see citing works

White Fat Progenitor Cells Reside in the Adipose Vasculature

Tang, W., Zeve, D., Suh, J. M., Bosnakovski, D., Kyba, M., Hammer, R. E., Tallquist, M. D., & Graff, J. M. (2008) · Science · doi:10.1126/science.1156232 · Cited by 1,113 · see citing works

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

Khan, T., Muise, E. S., Iyengar, P., Wang, Z. V., Chandalia, M., Abate, N., Zhang, B. B., Bonaldo, P., Chua, S., & Scherer, P. E. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01300-08 · Cited by 1,053 · see citing works

Fibrosis and adipose tissue dysfunction.

Sun, K., Tordjman, J., Clément, K., & Scherer, P. E. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.06.016 · Cited by 960 · see citing works

Identification of White Adipocyte Progenitor Cells In Vivo

Rodeheffer, M. S., Birsoy, K., & Friedman, J. M. (2008) · Cell · doi:10.1016/j.cell.2008.09.036 · Cited by 945 · see citing works

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Halberg, N., Khan, T., Trujillo, M. E., Wernstedt-Asterholm, I., Attie, A. D., Sherwani, S., Wang, Z. V., Landskroner-Eiger, S., Dineen, S., Magalang, U. J., et al. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00192-09 · Cited by 896 · see citing works

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

Holland, W. L., Miller, R. A., Wang, Z. V., Sun, K., Barth, B. M., Bui, H. H., Davis, K. E., Bikman, B. T., Halberg, N., Rutkowski, J. M., et al. (2011) · Nature Medicine · doi:10.1038/nm.2277 · Cited by 892 · see citing works

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of <i>ob</i> / <i>ob</i> and dietary obese mice

Ye, J., Gao, Z., Yin, J., & He, Q. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00435.2007 · Cited by 840 · see citing works

Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Blüher, M., Michael, M. D., Peroni, O. D., Ueki, K., Carter, N., Kahn, B. B., & Kahn, C. R. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00199-5 · Cited by 806 · see citing works

Proteomic Analysis of Proteins Associated with Lipid Droplets of Basal and Lipolytically Stimulated 3T3-L1 Adipocytes

Brasaemle, D., Dolios, G., Shapiro, L. S., & Wang, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m409340200 · Cited by 804 · see citing works

Reduced Adipose Tissue Oxygenation in Human Obesity

Pasarica, M., Sereda, O. R., Redman, L. M., Albarado, D. C., Hymel, D. T., Roan, L. E., Rood, J. C., Burk, D. H., & Smith, S. R. (2009) · Diabetes · doi:10.2337/db08-1098 · Cited by 786 · see citing works

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

Okada-Iwabu, M., Yamauchi, T., Iwabu, M., Honma, T., Hamagami, K.-I., Matsuda, K., Yamaguchi, M., Tanabe, H., Kimura-Someya, T., Shirouzu, M., et al. (2013) · Nature · doi:10.1038/nature12656 · Cited by 757 · see citing works

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

Tansey, J. T., Sztalryd, C., Gruia-Gray, J., Roush, D. L., Zee, J. V., Gavrilova, O., Reitman, M. L., Deng, C., Li, C., Kimmel, A. R., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.101042998 · Cited by 735 · see citing works

Defective Uptake and Utilization of Long Chain Fatty Acids in Muscle and Adipose Tissues of CD36 Knockout Mice

Coburn, C. T., Knapp, F. F., Febbraio, M., Beets, A. L., Silverstein, R. L., & Abumrad, N. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003826200 · Cited by 726 · see citing works

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

Holland, W. L., Bikman, B. T., Wang, L.-P., Yuguang, G., Sargent, K. M., Bulchand, S., Knotts, T. A., Shui, G., Clegg, D. J., Wenk, M. R., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci43378 · Cited by 705 · see citing works

Adipocytokines in Obesity and Metabolic Disease

Cao, H. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0339 · Cited by 705 · see citing works

Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

Turpin-Nolan, S. M., Nicholls, H. T., Willmes, D. M., Mourier, A., Brodesser, S., Wunderlich, C. M., Mauer, J., Xu, E., Hammerschmidt, P., Brönneke, H. S., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.08.002 · Cited by 693 · see citing works

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

Lee, Y., Petkova, A. P., Mottillo, E. P., & Granneman, J. G. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.03.009 · Cited by 676 · see citing works

Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling

Wernstedt Asterholm, I., Tao, C., Morley, T. S., Wang, Q. A., Delgado-Lopez, F., Wang, Z. V., & Scherer, P. E. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.05.005 · Cited by 668 · see citing works

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

Lass, A., Zimmermann, R., Oberer, M., & Zechner, R. (2010) · Progress in Lipid Research · doi:10.1016/j.plipres.2010.10.004 · Cited by 641 · see citing works

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone.

Wilson-Fritch, L., Nicoloro, S., Chouinard, M., Lazar, M. A., Chui, P. C., Leszyk, J., Straubhaar, J., Czech, M. P., & Corvera, S. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21752 · Cited by 616 · see citing works

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

Herman, M. A., Peroni, O. D., Villoria, J., Schön, M. R., Abumrad, N. A., Blüher, M., Klein, S., & Kahn, B. B. (2012) · Nature · doi:10.1038/nature10986 · Cited by 599 · see citing works

Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity

Lee, Y. S., Kim, J.-W., Osborne, O., Oh, D. Y., Sasik, R., Schenk, S., Chen, A., Chung, H., Murphy, A., Watkins, S. M., et al. (2014) · Cell · doi:10.1016/j.cell.2014.05.012 · Cited by 598 · see citing works

Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism

Holland, W. L., & Summers, S. A. (2008) · Endocrine Reviews · doi:10.1210/er.2007-0025 · Cited by 585 · see citing works

Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities

Razani, B., Combs, T. P., Wang, X., Frank, P. G., Park, D. S., Russell, R. G., Li, M., Tang, B., Jelicks, L. A., Scherer, P. E., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110970200 · Cited by 579 · see citing works

Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues

Waldén, T. B., Hansen, I. R., Timmons, J. A., Cannon, B., & Nedergaard, J. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00249.2011 · Cited by 565 · see citing works

Adipokines as novel biomarkers and regulators of the metabolic syndrome

Deng, Y., & Scherer, P. E. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05875.x · Cited by 558 · see citing works

Lipodystrophies: Genetic and Acquired Body Fat Disorders

Garg, A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1159 · Cited by 556 · see citing works

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

Holland, W., Adams, A., Brozinick, J., Bui, H., Miyauchi, Y., Kusminski, C., Bauer, S., Wade, M., Singhal, E., Cheng, C. C., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.019 · Cited by 525 · see citing works

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue.

Shepherd, P. R., Gnudi, L., Tozzo, E., Yang, H., Leach, F., & Kahn, B. B. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41516-5 · Cited by 520 · see citing works

The Browning of White Adipose Tissue: Some Burning Issues

Nedergaard, J., & Cannon, B. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.07.005 · Cited by 500 · see citing works

Regulation of Insulin-Stimulated Glucose Transporter GLUT4 Translocation and Akt Kinase Activity by Ceramide

Summers, S. A., Garza, L. A., Zhou, H., & Birnbaum, M. J. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.9.5457 · Cited by 475 · see citing works

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Henegar, C., Tordjman, J., Achard, V., Lacasa, D., Cremer, I., Guerre-Millo, M., Poitou, C., Basdevant, A., Stich, V., Viguerie, N., et al. (2008) · Genome Biology · doi:10.1186/gb-2008-9-1-r14 · Cited by 471 · see citing works

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

Kusminski, C. M., Holland, W. L., Sun, K., Park, J., Spurgin, S. B., Lin, Y., Askew, G. R., Simcox, J., McClain, D. A., Li, C., et al. (2012) · Nature Medicine · doi:10.1038/nm.2899 · Cited by 466 · see citing works

A Smooth Muscle-Like Origin for Beige Adipocytes

Long, J. Z., Svensson, K. J., Tsai, L. T.-Y., Zeng, X., Roh, H. C., Kong, X., Rao, R. R., Lou, J., Lokurkar, I. A., Baur, W. E., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.03.025 · Cited by 462 · see citing works

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

Ahmed, K., Tunaru, S., Tang, C., Müller, M., Gille, A., Sassmann, A., Hanson, J., & Offermanns, S. (2010) · Cell Metabolism · doi:10.1016/j.cmet.2010.02.012 · Cited by 443 · see citing works

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

Unger, R. H., & Scherer, P. E. (2010) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2010.01.009 · Cited by 436 · see citing works

A futile metabolic cycle activated in adipocytes by antidiabetic agents

Guan, H.-P., Li, Y., Jensen, M. V., Newgard, C. B., Steppan, C. M., & Lazar, M. A. (2002) · Nature Medicine · doi:10.1038/nm780 · Cited by 427 · see citing works

Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells

Gupta, R. K., Mepani, R. J., Kleiner, S., Lo, J. C., Khandekar, M. J., Cohen, P., Frontini, A., Bhowmick, D. C., Ye, L., Cinti, S., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.01.010 · Cited by 426 · see citing works

Dichotomous effects of VEGF-A on adipose tissue dysfunction

Sun, K., Asterholm, I. W., Kusminski, C. M., Bueno, A. C., Wang, Z. V., Pollard, J. W., Brekken, R. A., & Scherer, P. E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200447109 · Cited by 417 · see citing works

Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles.

Scherer, P. E., Lisanti, M. P., Baldini, G., Sargiacomo, M., Mastick, C. C., & Lodish, H. F. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.127.5.1233 · Cited by 412 · see citing works

Mitochondrial dysfunction in white adipose tissue

Kusminski, C. M., & Scherer, P. E. (2012) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2012.06.004 · Cited by 368 · see citing works

Mitochondria are impaired in the adipocytes of type 2 diabetic mice.

Choo, H.-J., Kim, J.-H., Kwon, O.-B., Lee, C. S., Mun, J. Y., Han, S. S., Yoon, Y.-S., Yoon, G., Choi, K.-M., & Ko, Y.-G. (2006) · Diabetologia · doi:10.1007/s00125-006-0170-2 · Cited by 365 · see citing works

PPARgamma induces the insulin-dependent glucose transporter GLUT4 in the absence of C/EBPalpha during the conversion of 3T3 fibroblasts into adipocytes.

Wu, Z., Xie, Y., Morrison, R. F., Bucher, N. L. R., & Farmer, S. R. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1244 · Cited by 356 · see citing works

Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue

Cohen, A. W., Razani, B., Wang, X., Combs, T. P., Williams, T. M., Scherer, P. E., & Lisanti, M. P. (2003) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00006.2003 · Cited by 351 · see citing works

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia and glucose intolerance

Liu, L.-B., Brown, D., Mckee, M., LeBrasseur, N., Yang, D., Albrecht, K. H., Ravid, K., & Pilch, P. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.07.008 · Cited by 350 · see citing works

Role of Caveolin-1 in the Modulation of Lipolysis and Lipid Droplet Formation

Cohen, A. W., Razani, B., Schubert, W., Williams, T. M., Wang, X., Iyengar, P., Brasaemle, D., Scherer, P. E., & Lisanti, M. P. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1261 · Cited by 320 · see citing works

Fat-specific Protein 27, a Novel Lipid Droplet Protein That Enhances Triglyceride Storage

Puri, V., Konda, S., Ranjit, S., Aouadi, M., Chawla, A., Chouinard, M., Chakladar, A., & Czech, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m707404200 · Cited by 316 · see citing works

Secretion of the Adipocyte-Specific Secretory Protein Adiponectin Critically Depends on Thiol-Mediated Protein Retention

Wang, Z. V., Schraw, T., Kim, J., Khan, T., Rajala, M. W., Follenzi, A., & Scherer, P. E. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00931-06 · Cited by 305 · see citing works

FATP1 Is an Insulin-Sensitive Fatty Acid Transporter Involved in Diet-Induced Obesity

Wu, Q., Ortegon, A. M., Tsang, B., Doege, H., Feingold, K. R., & Stahl, A. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.9.3455-3467.2006 · Cited by 296 · see citing works

The IRE1α-XBP1 Pathway of the Unfolded Protein Response Is Required for Adipogenesis

Sha, H., He, Y., Chen, H., Wang, C., Zenno, A., Shi, H., Yang, X., Zhang, X., & Qi, L. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.04.009 · Cited by 292 · see citing works

Development of insulin resistance in mice lacking PGC-1α in adipose tissues

Kleiner, S., Mepani, R. J., Laznik, D., Li, Y., Jurczak, M. J., Jornayvaz, F. R., Estall, J. L., Bhowmick, D. C., Shulman, G. I., & Spiegelman, B. M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1207287109 · Cited by 286 · see citing works

Hypoxia: A master regulator of microRNA biogenesis and activity

Nallamshetty, S., Chan, S. Y., & Loscalzo, J. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.05.022 · Cited by 281 · see citing works

The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis

Davis, K. E., D. Neinast, M., Sun, K., M. Skiles, W., D. Bills, J., A. Zehr, J., Zeve, D., D. Hahner, L., W. Cox, D., M. Gent, L., et al. (2013) · Molecular Metabolism · doi:10.1016/j.molmet.2013.05.006 · Cited by 278 · see citing works

GLUT4 exocytosis

Stöckli, J., Fazakerley, D. J., & James, D. E. (2011) · Journal of Cell Science · doi:10.1242/jcs.097063 · Cited by 276 · see citing works

Lipolysis: pathway under construction

Zechner, R., Bogner‐Strauß, J. G., Haemmerle, G., Lass, A., & Zimmermann, R. (2005) · Current Opinion in Lipidology · doi:10.1097/01.mol.0000169354.20395.1c · Cited by 274 · see citing works

Adipokines – removing road blocks to obesity and diabetes therapy

Blüher, M. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.01.005 · Cited by 273 · see citing works

UCP1 mRNA does not produce heat

Nedergaard, J., & Cannon, B. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.01.009 · Cited by 264 · see citing works

β3-Adrenergic Receptors on White and Brown Adipocytes Mediate β3-Selective Agonist-induced Effects on Energy Expenditure, Insulin Secretion, and Food Intake

Grujić, D., Susulic, V. S., Harper, M., Himms‐Hagen, J., Cunningham, B. A., Corkey, B. E., & Lowell, B. B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17686 · Cited by 255 · see citing works

Increased Fatty Acid Re-esterification by PEPCK Overexpression in Adipose Tissue Leads to Obesity Without Insulin Resistance

Franckhauser, S., MUÑOZ, S. A., Pujol, A., Casellas, A., Riu, E., Otaegui, P. J., Su, B., & Bosch, F. (2002) · Diabetes · doi:10.2337/diabetes.51.3.624 · Cited by 233 · see citing works

Selective Inhibition of Hypoxia-Inducible Factor 1α Ameliorates Adipose Tissue Dysfunction

Sun, K., Halberg, N., Khan, M., Magalang, U. J., & Scherer, P. E. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.00951-12 · Cited by 231 · see citing works

Adipose Tissue Expression of the Lipid Droplet–Associating Proteins S3-12 and Perilipin Is Controlled by Peroxisome Proliferator–Activated Receptor-γ

Dalen, K. T., Schoonjans, K., Ulven, S. M., Weedon-Fekjær, M. S., Bentzen, T. G., Koutníková, H., Auwerx, J. H., & Nebb, H. I. (2004) · Diabetes · doi:10.2337/diabetes.53.5.1243 · Cited by 212 · see citing works

Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway

Choi, S. M., Tucker, D. F., Gross, D. N., Easton, R., DiPilato, L. M., Dean, A. S., Monks, B. R., & Birnbaum, M. J. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00797-10 · Cited by 211 · see citing works

The Adipocyte as an Important Target Cell for Trypanosoma cruzi Infection

Combs, T. P., Nagajyothi, Mukherjee, S., de Almeida, C. J. G., Jelicks, L. A., Schubert, W., Lin, Y., Jayabalan, D. S., Zhao, D., Braunstein, V. L., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m412802200 · Cited by 209 · see citing works

Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes

Gao, C., Zhu, C., Zhao, Y., Chen, X.-H., Ji, C., Zhang, C., Zhu, J., Xia, Z., Tong, M., & Guo, X. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.01.039 · Cited by 203 · see citing works

Thiazolidinediones Block Fatty Acid Release by Inducing Glyceroneogenesis in Fat Cells

Tordjman, J., Chauvet, G., Quette, J., BEALE, E. G., Forest, C. D., & Antoine, B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m206999200 · Cited by 177 · see citing works

Regulation of MKL1 via actin cytoskeleton dynamics drives adipocyte differentiation

Nobusue, H., Onishi, N., Shimizu, T., Sugihara, E., Oki, Y., Sumikawa, Y., Chiyoda, T., Akashi, K., Saya, H., & Kano, K. (2014) · Nature Communications · doi:10.1038/ncomms4368 · Cited by 171 · see citing works

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

Nagajyothi, F., Machado, F. S., Burleigh, B. A., Jelicks, L. A., Scherer, P. E., Mukherjee, S., Lisanti, M. P., Weiss, L. M., Garg, N. J., & Tanowitz, H. B. (2012) · Cellular Microbiology · doi:10.1111/j.1462-5822.2012.01764.x · Cited by 168 · see citing works

Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways

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Caveolin-1 is required for fatty acid translocase (FAT/CD36) localization and function at the plasma membrane of mouse embryonic fibroblasts

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