Cotman, Carl W.

β-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease

Cummings, B. J., Pike, C. J., Shankle, R., & Cotman, C. W. (1996) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 305

Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro

Pike, C. J., Overman, M. J., & Cotman, C. W. (1995) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 302

Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease

Berchtold, N. C., Coleman, P. D., Cribbs, D. H., Rogers, J., Gillen, D. L., & Cotman, C. W. (2013) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 298

The exercise-induced expression of BDNF within the hippocampus varies across life-span

Adlard, P. A., Perreau, V. M., & Cotman, C. W. (2005) · Neurobiology of Aging

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

Cited by 260

Brain-Derived Neurotrophic Factor-Dependent Synaptic Plasticity Is Suppressed by Interleukin-1β via p38 Mitogen-Activated Protein Kinase

Tong, L., Prieto, G. A., Kramár, E. A., Smith, E. D., Cribbs, D. H., Lynch, G., & Cotman, C. W. (2012) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 254

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J., Dombroski, B. A., Baker, M. C., Soto-Ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., et al. (2012) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 240

Caspase-3 activation as a bifurcation point between plasticity and cell death

Snigdha, S., Smith, E. D., Prieto, G. A., & Cotman, C. W. (2012) · Neuroscience Bulletin

Cell death mechanisms and regulationNeuroscience and Neuropharmacology Research

Cited by 227

Localization and Cell Association of C1q in Alzheimer's Disease Brain

Afagh, A., Cummings, B. J., Cribbs, D. H., Cotman, C. W., & Tenner, A. J. (1996) · Experimental Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 224

Interleukin-1β impairs brain derived neurotrophic factor-induced signal transduction

Tong, L., Balazs, R., Soiampornkul, R., Thangnipon, W., & Cotman, C. W. (2008) · Neurobiology of Aging

Nerve injury and regenerationNeuroinflammation and Neurodegeneration Mechanisms

Cited by 222

β-Amyloid Peptide at Sublethal Concentrations Downregulates Brain-Derived Neurotrophic Factor Functions in Cultured Cortical Neurons

Tong, L., Balazs, R., Thornton, P. L., & Cotman, C. W. (2004) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNerve injury and regeneration

Cited by 221

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

Astarita, G., Jung, K.-M., Berchtold, N. C., Nguyen, V. Q., Gillen, D. L., Head, E., Cotman, C. W., & Piomelli, D. (2010) · PLoS ONE

Fatty Acid Research and HealthAlzheimer's disease research and treatments

Cited by 218

Exercise improves cognition and hippocampal plasticity in APOE ɛ4 mice

Nichol, K., Deeny, S. P., Seif, J., Camaclang, K., & Cotman, C. W. (2009) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 213

β-Amyloid-(1–42) Impairs Activity-dependent cAMP-response Element-binding Protein Signaling in Neurons at Concentrations in Which Cell Survival Is Not Compromised

Tong, L., Thornton, P. L., Balazs, R., & Cotman, C. W. (2001) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 206

Inflammatory changes parallel the early stages of Alzheimer disease

Parachikova, A., Agadjanyan, M. G., Cribbs, D. H., Blurton-Jones, M., Perreau, V., Rogers, J., Beach, T. G., & Cotman, C. W. (2007) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 203

Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: Relevance to Alzheimer's disease

Opii, W. O., Joshi, G., Head, E., Milgram, N. W., Muggenburg, B. A., Klein, J. B., Pierce, W. M., Cotman, C. W., & Butterfield, D. A. (2008) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 202

Development of cholinergic innervation in the hippocampal formation of the rat

Matthews, D. A., Nadler, J. V., Lynch, G. S., & Cotman, C. W. (1974) · Developmental Biology

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 201

The Role of Caspase Cleavage of Tau in Alzheimer Disease Neuropathology

Cotman, C. W., Poon, W. W., Rissman, R. A., & Blurton-Jones, M. (2005) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 199

Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition

Parachikova, A., Nichol, K. E., & Cotman, C. W. (2008) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 193

Exercise and Sodium Butyrate Transform a Subthreshold Learning Event into Long-Term Memory via a Brain-Derived Neurotrophic factor-Dependent Mechanism

Intlekofer, K. A., Berchtold, N. C., Malvaez, M., Carlos, A. J., McQuown, S. C., Cunningham, M. J., Wood, M. A., & Cotman, C. W. (2013) · Neuropsychopharmacology

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 190

β-Amyloid Induces Local Neurite Degeneration in Cultured Hippocampal Neurons: Evidence for Neuritic Apoptosis

Ivins, K. J., Bui, E. T. N., & Cotman, C. W. (1998) · Neurobiology of Disease

Alzheimer's disease research and treatmentsCell death mechanisms and regulation

Cited by 164

Acrolein, a Toxicant in Cigarette Smoke, Causes Oxidative Damage and Mitochondrial Dysfunction in RPE Cells: Protection by (R)-α-Lipoic Acid

Jia, L., Liu, Z., Sun, L., Miller, S. S., Ames, B. N., Cotman, C. W., & Liu, J. (2007) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsAntioxidant Activity and Oxidative Stress

Cited by 164

Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer’s disease

Astarita, G., Jung, K.-M., Vasilevko, V., DiPatrizio, N. V., Martin, S. K., Cribbs, D. H., Head, E., Cotman, C. W., & Piomelli, D. (2011) · PLoS ONE

Alzheimer's disease research and treatmentsFatty Acid Research and Health

Cited by 146

β-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology

Pike, C. J., Cummings, B. J., & Cotman, C. W. (1992) · Neuroreport

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 131

Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus

Prieto, G. A., Snigdha, S., Baglietto-Vargas, D., Smith, E. D., Berchtold, N. C., Tong, L., Ajami, D., LaFerla, F. M., Rebek, J., & Cotman, C. W. (2015) · Proceedings of the National Academy of Sciences

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 126