Most cited biochemistry, genetics and molecular biology papers
- Verified
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
Yoon, J. C., Puigserver, P., Chen, G., Donovan, J., Wu, Z., Rhee, J., Adelmant, G., Stafford, J., Kahn, C. R., Granner, D. K., et al. (2001) · Nature
Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors
Cited by 1,821
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The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases
Cabral-Pacheco, G. A., Garza-Veloz, I., Castruita-De la Rosa, C., Ramirez-Acuña, J. M., Perez-Romero, B. A., Guerrero-Rodriguez, J. F., Martinez-Avila, N., & Martinez-Fierro, M. L. (2020) · International Journal of Molecular Sciences
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 1,820
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NRF2, a Transcription Factor for Stress Response and Beyond
He, F., Ru, X., & Wen, T. (2020) · International Journal of Molecular Sciences
Genomics, phytochemicals, and oxidative stressEndoplasmic Reticulum Stress and Disease
Cited by 1,820
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Hitchhiking Under Positive Darwinian Selection
Fay, J. C., & Wu, C.-I. (2000) · Genetics
Evolution and Genetic DynamicsGenetic diversity and population structure
Cited by 1,819
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Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
Galipeau, J., & Sensébé, L. (2018) · Cell Stem Cell
Mesenchymal stem cell researchPeriodontal Regeneration and Treatments
Cited by 1,819
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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
Chang, J., Wang, Y., Shao, L., Laberge, R.-M., Demaria, M., Campisi, J., Janakiraman, K., Sharpless, N. E., Ding, S., Feng, W., et al. (2016) · Nature Medicine
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,819
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HSP90 at the hub of protein homeostasis: emerging mechanistic insights
Taipale, M., Jarosz, D. F., & Lindquist, S. (2010) · Nature Reviews Molecular Cell Biology
Heat shock proteins researchUbiquitin and proteasome pathways
Cited by 1,818
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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
Mendoza, M. C., Er, E. E., & Blenis, J. (2011) · Trends in Biochemical Sciences
PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling
Cited by 1,817
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The PPARs: From Orphan Receptors to Drug Discovery
Willson, T. M., Brown, P. J., Sternbach, D. D., & Henke, B. R. (2000) · Journal of Medicinal Chemistry
Peroxisome Proliferator-Activated ReceptorsNuclear Receptors and Signaling
Cited by 1,816
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Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function
Chen, L., Willis, S. N., Wei, A., Smith, B. J., Fletcher, J. I., Hinds, M. G., Colman, P. M., Day, C. L., Adams, J. M., & Huang, D. C. S. (2005) · Molecular Cell
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 1,816
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Highly Recurrent TERT Promoter Mutations in Human Melanoma
Huang, F. W., Hodis, E., Xu, M. J., Kryukov, G. V., Chin, L., & Garraway, L. A. (2013) · Science
Telomeres, Telomerase, and SenescenceChromatin Remodeling and Cancer
Cited by 1,816
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Structural Variation of Chromosomes in Autism Spectrum Disorder
Marshall, C. R., Noor, A., Vincent, J. B., Lionel, A. C., Feuk, L., Skaug, J., Shago, M., Moessner, R., Pinto, D., Ren, Y., et al. (2008) · The American Journal of Human Genetics
Genomic variations and chromosomal abnormalitiesAutism Spectrum Disorder Research
Cited by 1,815
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Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
Boija, A., Klein, I. A., Sabari, B. R., Dall’Agnese, A., Coffey, E. L., Zamudio, A. V., Li, C. H., Shrinivas, K., Manteiga, J. C., Hannett, N. M., et al. (2018) · Cell
Genomics and Chromatin DynamicsRNA Research and Splicing
Cited by 1,815
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Histone acetylation and transcriptional regulatory mechanisms
Struhl, K. (1998) · Genes & Development
Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research
Cited by 1,815
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The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
Coutinho, A. E., & Chapman, K. E. (2011) · Molecular and Cellular Endocrinology
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 1,815
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Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery
Zufferey, R., Dull, T., Mandel, R. J., Bukovsky, A., Quiroz, D., Naldini, L., & Trono, D. (1998) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 1,815
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YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA
Shi, H., Wang, X., Lu, Z., Zhao, B. S., Ma, H., Hsu, P. J., Liu, C., & He, C. (2017) · Cell Research
RNA modifications and cancerRNA and protein synthesis mechanisms
Cited by 1,815
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Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews
Photodynamic Therapy Research StudiesNanoplatforms for cancer theranostics
Cited by 1,813
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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
Wu, S., Rhee, K.-J., Albesiano, E., Rabizadeh, S., Wu, X., Yen, H.-R., Huso, D. L., Brancati, F. L., Wick, E., McAllister, F., et al. (2009) · Nature Medicine
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 1,812
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RNA delivery by extracellular vesicles in mammalian cells and its applications
O’Brien, K., Breyne, K., Ughetto, S., Laurent, L. C., & Breakefield, X. O. (2020) · Nature Reviews Molecular Cell Biology
Extracellular vesicles in diseaseRNA Interference and Gene Delivery
Cited by 1,811
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Detecting Individual Sites Subject to Episodic Diversifying Selection
Murrell, B., Wertheim, J. O., Moola, S., Weighill, T., Scheffler, K., & Kosakovsky Pond, S. L. (2012) · PLoS Genetics
Evolution and Genetic DynamicsGenomics and Phylogenetic Studies
Cited by 1,811
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Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
van Oven, M., & Kayser, M. (2009) · Human Mutation
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 1,810
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Translation of CircRNAs
Pamudurti, N. R., Bartok, O., Jens, M., Ashwal-Fluss, R., Stottmeister, C., Ruhe, L., Hanan, M., Wyler, E., Perez-Hernandez, D., Ramberger, E., et al. (2017) · Molecular Cell
Circular RNAs in diseasesRNA and protein synthesis mechanisms
Cited by 1,810
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Nonfilamentous C. albicans Mutants Are Avirulent
Lo, H.-J., Köhler, J. R., DiDomenico, B., Loebenberg, D., Cacciapuoti, A., & Fink, G. R. (1997) · Cell
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 1,809
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