Most cited biochemistry, genetics and molecular biology papers
- Verified
The microbiota in adaptive immune homeostasis and disease
Honda, K., & Littman, D. R. (2016) · Nature
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 1,846
- Verified
A new bioinformatics analysis tools framework at EMBL-EBI
Goujon, M., McWilliam, H., Li, W., Valentin, F., Squizzato, S., Paern, J., & Lopez, R. (2010) · Nucleic Acids Research
Genomics and Phylogenetic StudiesScientific Computing and Data Management
Cited by 1,846
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PI3K pathway alterations in cancer: variations on a theme
Yuan, T. L., & Cantley, L. C. (2008) · Oncogene
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,845
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Functions of RANKL/RANK/OPG in bone modeling and remodeling
Boyce, B. F., & Xing, L. (2008) · Archives of Biochemistry and Biophysics
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,844
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Automated design of synthetic ribosome binding sites to control protein expression
Salis, H. M., Mirsky, E. A., & Voigt, C. A. (2009) · Nature Biotechnology
RNA and protein synthesis mechanismsMicrobial Metabolic Engineering and Bioproduction
Cited by 1,844
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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.
Cheng, K. C., Cahill, D. S., Kasai, H., Nishimura, S., & Loeb, L. A. (1992) · Journal of Biological Chemistry
DNA Repair MechanismsCarcinogens and Genotoxicity Assessment
Cited by 1,844
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Photosynthetic energy conversion: natural and artificial
Barber, J. (2009) · Chem. Soc. Rev.
Photosynthetic Processes and MechanismsAdvanced Photocatalysis Techniques
Cited by 1,843
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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
Li, Y., Willer, C. J., Ding, J., Scheet, P., & Abecasis, G. R. (2010) · Genetic Epidemiology
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 1,843
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Geometric cues for directing the differentiation of mesenchymal stem cells
Kilian, K. A., Bugarija, B., Lahn, B. T., & Mrksich, M. (2010) · Proceedings of the National Academy of Sciences
Cellular Mechanics and InteractionsMesenchymal stem cell research
Cited by 1,841
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Accurate circular consensus long-read sequencing improves variant detection and assembly of a human genome
Wenger, A. M., Peluso, P., Rowell, W. J., Chang, P.-C., Hall, R. J., Concepcion, G. T., Ebler, J., Fungtammasan, A., Kolesnikov, A., Olson, N. D., et al. (2019) · Nature Biotechnology
Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities
Cited by 1,841
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Identification of hundreds of conserved and nonconserved human microRNAs
Bentwich, I., Avniel, A., Karov, Y., Aharonov, R., Gilad, S., Barad, O., Barzilai, A., Einat, P., Einav, U., Meiri, E., et al. (2005) · Nature Genetics
MicroRNA in disease regulationPlant Molecular Biology Research
Cited by 1,841
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A universal SNP and small-indel variant caller using deep neural networks
Poplin, R., Chang, P.-C., Alexander, D., Schwartz, S., Colthurst, T., Ku, A., Newburger, D., Dijamco, J., Nguyen, N., Afshar, P. T., et al. (2018) · Nature Biotechnology
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 1,840
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Genomic Selection in Plant Breeding: Methods, Models, and Perspectives
Crossa, J., Pérez-Rodríguez, P., Cuevas, J., Montesinos-López, O., Jarquín, D., de los Campos, G., Burgueño, J., González-Camacho, J. M., Pérez-Elizalde, S., Beyene, Y., et al. (2017) · Trends in Plant Science
Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals
Cited by 1,839
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Searching for genetic determinants in the new millennium
Risch, N. J. (2000) · Nature
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,839
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The complete genome of an individual by massively parallel DNA sequencing
Wheeler, D. A., Srinivasan, M., Egholm, M., Shen, Y., Chen, L., McGuire, A., He, W., Chen, Y.-J., Makhijani, V., Roth, G. T., et al. (2008) · Nature
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 1,838
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Predicting DNA duplex stability from the base sequence
Breslauer, K. J., Frank, R., Blöcker, H., & Marky, L. A. (1986) · Proceedings of the National Academy of Sciences
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 1,837
- Verified
GenABEL: an R library for genome-wide association analysis
Aulchenko, Y. S., Ripke, S., Isaacs, A., & van Duijn, C. M. (2007) · Bioinformatics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,836
- Verified
THE INTERACTION OF SELECTION AND LINKAGE. I. GENERAL CONSIDERATIONS; HETEROTIC MODELS
Lewontin, R. C. (1964) · Genetics
Evolution and Genetic DynamicsGenetic Associations and Epidemiology
Cited by 1,835
- Verified
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
Schellenberger, J., Que, R., Fleming, R. M. T., Thiele, I., Orth, J. D., Feist, A. M., Zielinski, D. C., Bordbar, A., Lewis, N. E., Rahmanian, S., et al. (2011) · Nature Protocols
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 1,835
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Concise review: MSC-derived exosomes for cell-free therapy
Phinney, D. G., & Pittenger, M. F. (2017) · Stem Cells
Extracellular vesicles in diseaseMesenchymal stem cell research
Cited by 1,834
- Verified
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Franchi, L., Eigenbrod, T., Muñoz-Planillo, R., & Nuñez, G. (2009) · Nature Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,834
- Verified
Twilight zone of protein sequence alignments
Rost, B. (1999) · Protein Engineering, Design and Selection
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 1,833
- Verified
Direct signaling between platelets and cancer cells induces an epithelial–mesenchymal-like transition and promotes metastasis
Labelle, M., Begum, S., & Hynes, R. O. (2011) · Cancer Cell
TGF-β signaling in diseasesCancer Cells and Metastasis
Cited by 1,833
- Verified
Requirement of bic/microRNA-155 for Normal Immune Function
Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., et al. (2007) · Science
MicroRNA in disease regulationT-cell and B-cell Immunology
Cited by 1,833
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