Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

Nicklin, P., Bergman, P., Zhang, B., Triantafellow, E., Wang, H., Nyfeler, B., Yang, H., Hild, M., Kung, C., Wilson, C., et al. (2009) · Cell

Amino Acid Enzymes and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 1,798

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Shaw, R. J., Kosmatka, M., Bardeesy, N., Hurley, R. L., Witters, L. A., DePinho, R. A., & Cantley, L. C. (2004) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 1,797

Genetics of diabetes mellitus and diabetes complications

Cole, J. B., & Florez, J. C. (2020) · Nature Reviews Nephrology

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 1,797

Sarcopenia: Aging-Related Loss of Muscle Mass and Function

Larsson, L., Degens, H., Li, M., Salviati, L., Lee, Y. I., Thompson, W., Kirkland, J. L., & Sandri, M. (2019) · Physiological Reviews

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 1,797

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

Banin, S., Moyal, L., Shieh, S.-Y., Taya, Y., Anderson, C. W., Chessa, L., Smorodinsky, N. I., Prives, C., Reiss, Y., Shiloh, Y., et al. (1998) · Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,797

PCNA, the Maestro of the Replication Fork

Moldovan, G.-L., Pfander, B., & Jentsch, S. (2007) · Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 1,796

Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Elefant, N., Paul, F., Zaretsky, I., Mildner, A., Cohen, N., Jung, S., Tanay, A., et al. (2014) · Science

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,795

A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer

Goss, P. E., Ingle, J. N., Martino, S., Robert, N. J., Muss, H. B., Piccart, M. J., Castiglione, M., Tu, D., Shepherd, L. E., Pritchard, K. I., et al. (2003) · New England Journal of Medicine

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 1,795

Nrf2 signaling pathway: pivotal roles in inflammation

Ahmed, S. M. U., Luo, L., Namani, A., Wang, X. J., & Tang, X. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways

Cited by 1,794

Programmed Cell Death Induced by Ceramide

Obeid, L. M., Linardic, C. M., Karolak, L. A., & Hannun, Y. A. (1993) · Science

Sphingolipid Metabolism and SignalingCell death mechanisms and regulation

Cited by 1,794

Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome

Habashi, J. P., Judge, D. P., Holm, T. M., Cohn, R. D., Loeys, B. L., Cooper, T. K., Myers, L., Klein, E. C., Liu, G., Calvi, C., et al. (2006) · Science

Connective tissue disorders researchAortic aneurysm repair treatments

Cited by 1,794

Chromatin accessibility and the regulatory epigenome

Klemm, S. L., Shipony, Z., & Greenleaf, W. J. (2019) · Nature Reviews Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,793

PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

Wang, K., Li, M., Hadley, D., Liu, R., Glessner, J., Grant, S. F. A., Hakonarson, H., & Bucan, M. (2007) · Genome Research

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 1,792

You are what you eat: Diet, health and the gut microbiota

Zmora, N., Suez, J., & Elinav, E. (2019) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthNutritional Studies and Diet

Cited by 1,792

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Kamata, H., Honda, S.-I., Maeda, S., Chang, L., Hirata, H., & Karin, M. (2005) · Cell

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 1,792

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

Metallo, C. M., Gameiro, P. A., Bell, E. L., Mattaini, K. R., Yang, J., Hiller, K., Jewell, C. M., Johnson, Z. R., Irvine, D. J., Guarente, L., et al. (2012) · Nature

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 1,791

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*

Pratt, W. B., & Toft, D. O. (1997) · Endocrine Reviews

Heat shock proteins researchEstrogen and related hormone effects

Cited by 1,791

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

Chi, S. W., Zang, J. B., Mele, A., & Darnell, R. B. (2009) · Nature

MicroRNA in disease regulationRNA Research and Splicing

Cited by 1,791

CAFE: a computational tool for the study of gene family evolution

De Bie, T., Cristianini, N., Demuth, J. P., & Hahn, M. W. (2006) · Bioinformatics

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 1,790

The keystone-pathogen hypothesis

Hajishengallis, G., Darveau, R. P., & Curtis, M. A. (2012) · Nature Reviews Microbiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,790

Preoperative Chemotherapy: Updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27

Rastogi, P., Anderson, S. J., Bear, H. D., Geyer, C. E., Kahlenberg, M. S., Robidoux, A., Margolese, R. G., Hoehn, J. L., Vogel, V. G., Dakhil, S. R., et al. (2008) · Journal of Clinical Oncology

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 1,789

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

Yoshida, H., Hayashi, S.-I., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T., Shultz, L. D., & Nishikawa, S.-I. (1990) · Nature

Bone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research

Cited by 1,789

A protocol for generating a high-quality genome-scale metabolic reconstruction

Thiele, I., & Palsson, B. Ø. (2010) · Nature Protocols

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 1,789

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

Kostic, A. D., Xavier, R. J., & Gevers, D. (2014) · Gastroenterology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 1,789