Most cited biochemistry, genetics and molecular biology papers
- Verified
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
Lyden, D., Hattori, K., Dias, S., Costa, C., Blaikie, P., Butros, L., Chadburn, A., Heissig, B., Marks, W., Witte, L., et al. (2001) · Nature Medicine
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 1,860
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Kinesin superfamily motor proteins and intracellular transport
Hirokawa, N., Noda, Y., Tanaka, Y., & Niwa, S. (2009) · Nature Reviews Molecular Cell Biology
Microtubule and mitosis dynamicsCellular transport and secretion
Cited by 1,859
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Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences
Cox, L. M., Yamanishi, S., Sohn, J., Alekseyenko, A. V., Leung, J. M., Cho, I., Kim, S. G., Li, H., Gao, Z., Mahana, D., et al. (2014) · Cell
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 1,859
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The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions
Oughtred, R., Rust, J., Chang, C., Breitkreutz, B., Stark, C., Willems, A., Boucher, L., Leung, G., Kolas, N., Zhang, F., et al. (2021) · Protein Science
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 1,858
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Persister cells
Lewis, K. (2010) · Annual Review of Microbiology
Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing
Cited by 1,858
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Estrogen receptors: how do they signal and what are their targets
Heldring, N., Pike, A., Andersson, S., Matthews, J., Cheng, G., Hartman, J., Tujague, M., Ström, A., Treuter, E., Warner, M., et al. (2007) · Physiological Reviews
Estrogen and related hormone effectsBreast Cancer Treatment Studies
Cited by 1,857
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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
Kim, S., Kim, D., Cho, S. W., Kim, J., & Kim, J.-S. (2014) · Genome Research
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,856
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Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.
Kong, Y.-Y., Feige, U., Sarosi, I., Bolon, B., Tafuri, A., Morony, S., Capparelli, C., Li, J., Elliott, R., McCabe, S., et al. (1999) · Nature
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 1,856
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Extensive translation of circular RNAs driven by N6-methyladenosine
Yang, Y., Fan, X., Mao, M., Song, X., Wu, P., Zhang, Y., Jin, Y., Yang, Y., Chen, L.-L., Wang, Y., et al. (2017) · Cell Research
Circular RNAs in diseasesRNA modifications and cancer
Cited by 1,855
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A genomic and functional inventory of deubiquitinating enzymes.
Nijman, S. M. B., Luna-Vargas, M. P. A., Velds, A., Brummelkamp, T. R., Dirac, A. M. G., Sixma, T. K., & Bernards, R. (2005) · Cell
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 1,854
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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
Hacein-Bey-Abina, S., Garrigue, A., Wang, G. P., Soulier, J., Lim, A., Morillon, E., Clappier, E., Caccavelli, L., Delabesse, E., Beldjord, K., et al. (2008) · Journal of Clinical Investigation
Virus-based gene therapy researchCAR-T cell therapy research
Cited by 1,854
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Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
Patterson, C. C., Dahlquist, G. G., Gyürüs, E., Green, A., & Soltész, G. (2009) · The Lancet
Diabetes and associated disordersDiabetes Management and Research
Cited by 1,854
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Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
Yakes, F. M., & Van Houten, B. (1997) · Proceedings of the National Academy of Sciences
Mitochondrial Function and PathologyDNA Repair Mechanisms
Cited by 1,854
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Defining the role of common variation in the genomic and biological architecture of adult human height
The Electronic Medical Records and Genomics (eMERGE) Consortium, Wood, A. R., The MIGen Consortium, The PAGE Consortium, Study, T. L. C., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., et al. (2014) · Nature Genetics
Genetic Associations and EpidemiologyGenetics and Physical Performance
Cited by 1,853
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Scater: Pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R
McCarthy, D. J., Campbell, K. R., Lun, A. T. L., & Wills, Q. F. (2017) · Bioinformatics
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,852
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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., & Plasterk, R. H. A. (2001) · Genes & Development
RNA Interference and Gene DeliveryPlant Molecular Biology Research
Cited by 1,852
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RNA-guided genetic silencing systems in bacteria and archaea
Wiedenheft, B., Sternberg, S. H., & Doudna, J. A. (2012) · Nature
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 1,851
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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
Study, P. A. R. I. S., Jamain, S., Quach, H., Betancur, C., Råstam, M., Colineaux, C., Gillberg, I. C., Soderstrom, H., Giros, B., Leboyer, M., et al. (2003) · Nature Genetics
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 1,851
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An Oncogene-Induced DNA Damage Model for Cancer Development
Halazonetis, T. D., Gorgoulis, V. G., & Bartek, J. (2008) · Science
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,851
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A linear complexity phasing method for thousands of genomes
Delaneau, O., Marchini, J., & Zagury, J.-F. (2012) · Nature Methods
Genetic Associations and EpidemiologyGenomics and Phylogenetic Studies
Cited by 1,850
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Risks of cancer in BRCA1-mutation carriers
FORD, D. (1994) · The Lancet
BRCA gene mutations in cancerMultiple and Secondary Primary Cancers
Cited by 1,850
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Genome-wide association studies
Uffelmann, E., Huang, Q. Q., Munung, N. S., de Vries, J., Okada, Y., Martin, A. R., Martin, H. C., Lappalainen, T., & Posthuma, D. (2021) · Nature Reviews Methods Primers
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,849
- Verified
Mechanisms involved in the side effects of glucocorticoids
SCHACKE, H. (2002) · Pharmacology & Therapeutics
Estrogen and related hormone effectsAdrenal Hormones and Disorders
Cited by 1,847
- Verified
Microenvironmental regulation of tumour angiogenesis
De Palma, M., Biziato, D., & Petrova, T. V. (2017) · Nature Reviews Cancer
Angiogenesis and VEGF in CancerCancer Cells and Metastasis
Cited by 1,847
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