Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Nakashima, T., Hayashi, M., Fukunaga, T., Kurata, K., Oh-hora, M., Feng, J. Q., Bonewald, L. F., Kodama, T., Wutz, A., Wagner, E. F., et al. (2011) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,778

The Diploid Genome Sequence of an Individual Human

Levy, S., Sutton, G., Ng, P. C., Feuk, L., Halpern, A. L., Walenz, B. P., Axelrod, N., Huang, J., Kirkness, E. F., Denisov, G., et al. (2007) · PLoS Biology

Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities

Cited by 1,778

Gut microbiota and IBD: causation or correlation?

Ni, J., Wu, G. D., Albenberg, L., & Tomov, V. T. (2017) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 1,778

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

Shimazu, T., Hirschey, M. D., Newman, J., He, W., Shirakawa, K., Le Moan, N., Grueter, C. A., Lim, H., Saunders, L. R., Stevens, R. D., et al. (2013) · Science

Histone Deacetylase Inhibitors ResearchSirtuins and Resveratrol in Medicine

Cited by 1,777

The cornified envelope: a model of cell death in the skin

Candi, E., Schmidt, R., & Melino, G. (2005) · Nature Reviews Molecular Cell Biology

Skin and Cellular Biology ResearchCell death mechanisms and regulation

Cited by 1,776

Metagenomic microbial community profiling using unique clade-specific marker genes

Segata, N., Waldron, L., Ballarini, A., Narasimhan, V., Jousson, O., & Huttenhower, C. (2012) · Nature Methods

Genomics and Phylogenetic StudiesGut microbiota and health

Cited by 1,776

A single-cell and spatially resolved atlas of human breast cancers

Wu, S. Z., Al-Eryani, G., Roden, D. L., Junankar, S., Harvey, K., Andersson, A., Thennavan, A., Wang, C., Torpy, J. R., Bartonicek, N., et al. (2021) · Nature Genetics

Single-cell and spatial transcriptomicsBreast Cancer Treatment Studies

Cited by 1,775

Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae

Lin, S.-J., Defossez, P.-A., & Guarente, L. (2000) · Science

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 1,775

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes

Harding, C., Heuser, J., & Stahl, P. (1983) · The Journal of Cell Biology

Cellular transport and secretionIron Metabolism and Disorders

Cited by 1,775

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

Hellström, M., Phng, L.-K., Hofmann, J. J., Wallgard, E., Coultas, L., Lindblom, P., Alva, J., Nilsson, A.-K., Karlsson, L., Gaiano, N., et al. (2007) · Nature

Angiogenesis and VEGF in CancerDevelopmental Biology and Gene Regulation

Cited by 1,775

Conserved cell types with divergent features in human versus mouse cortex

Hodge, R. D., Bakken, T. E., Miller, J. A., Smith, K. A., Barkan, E. R., Graybuck, L. T., Close, J. L., Long, B., Johansen, N., Penn, O., et al. (2019) · Nature

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 1,775

Why do we age?

Kirkwood, T. B. L., & Austad, S. N. (2000) · Nature

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 1,774

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

Tchkonia, T., Zhu, Y., van Deursen, J., Campisi, J., & Kirkland, J. L. (2013) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,774

Siderophore-Based Iron Acquisition and Pathogen Control

Miethke, M., & Marahiel, M. A. (2007) · Microbiology and Molecular Biology Reviews

Bacterial Genetics and BiotechnologyIron Metabolism and Disorders

Cited by 1,774

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

Gomes, M. D., Lecker, S. H., Jagoe, R. T., Navon, A., & Goldberg, A. L. (2001) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersUbiquitin and proteasome pathways

Cited by 1,774

Brownian motion in biological membranes

Saffman, P. G., & Delbrück, M. (1975) · Proceedings of the National Academy of Sciences

Lipid Membrane Structure and BehaviorDiffusion Coefficients in Liquids

Cited by 1,773

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

Straussman, R., Morikawa, T., Shee, K., Barzily-Rokni, M., Qian, Z. R., Du, J., Davis, A., Mongare, M. M., Gould, J., Frederick, D. T., et al. (2012) · Nature

Melanoma and MAPK PathwaysCancer Cells and Metastasis

Cited by 1,771

Interactome Networks and Human Disease

Vidal, M., Cusick, M. E., & Barabási, A.-L. (2011) · Cell

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,771

Digital PCR

Vogelstein, B., & Kinzler, K. W. (1999) · Proceedings of the National Academy of Sciences

Molecular Biology Techniques and ApplicationsCancer Genomics and Diagnostics

Cited by 1,770

Glutamine addiction: a new therapeutic target in cancer

Wise, D. R., & Thompson, C. B. (2010) · Trends in Biochemical Sciences

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1,770

High burden and pervasive positive selection of somatic mutations in normal human skin

Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., Wedge, D. C., Fullam, A., Alexandrov, L. B., Tubio, J. M., et al. (2015) · Science

Cancer Genomics and DiagnosticsNonmelanoma Skin Cancer Studies

Cited by 1,770

Single-cell chromatin state analysis with Signac

Stuart, T., Srivastava, A., Madad, S., Lareau, C. A., & Satija, R. (2021) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 1,769

Dysbiosis and the immune system

Levy, M., Kolodziejczyk, A. A., Thaiss, C. A., & Elinav, E. (2017) · Nature Reviews Immunology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 1,769

AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients

Batchelor, T. T., Sorensen, A. G., di Tomaso, E., Zhang, W.-T., Duda, D. G., Cohen, K. S., Kozak, K. R., Cahill, D. P., Chen, P.-J., Zhu, M., et al. (2007) · Cancer Cell

Angiogenesis and VEGF in CancerGlioma Diagnosis and Treatment

Cited by 1,769