Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Chromosomal Subunits in Active Genes Have an Altered Conformation: Globin genes are digested by deoxyribonuclease I in red blood cell nuclei but not in fibroblast nuclei.

Weintraub, H., & Groudine, M. (1976) · Science

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 1,809

Circular RNA: a new star of noncoding RNAs

Qu, S., Yang, X., Li, X., Wang, J., Gao, Y., Shang, R., Sun, W., Dou, K., & Li, H. (2015) · Cancer Letters

Circular RNAs in diseasesRNA Research and Splicing

Cited by 1,808

Dietary fiber and prebiotics and the gastrointestinal microbiota

Holscher, H. D. (2017) · Gut Microbes

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 1,808

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

Cosby, K., Partovi, K. S., Crawford, J. H., Patel, R. P., Reiter, C. D., Martyr, S., Yang, B. K., Waclawiw, M. A., Zalos, G., Xu, X., et al. (2003) · Nature Medicine

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 1,807

Single-cell RNA sequencing to explore immune cell heterogeneity

Papalexi, E., & Satija, R. (2018) · Nature Reviews Immunology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,806

Collagen reorganization at the tumor-stromal interface facilitates local invasion

Provenzano, P. P., Eliceiri, K. W., Campbell, J. M., Inman, D. R., White, J. G., & Keely, P. J. (2006) · BMC Medicine

Cellular Mechanics and InteractionsCancer Cells and Metastasis

Cited by 1,804

Mitochondrial form and function

Friedman, J. R., & Nunnari, J. (2014) · Nature

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,803

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

Thoreen, C. C., Kang, S. A., Chang, J. W., Liu, Q., Zhang, J., Gao, Y., Reichling, L. J., Sim, T., Sabatini, D. M., & Gray, N. S. (2009) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 1,803

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

Nott, T. J., Petsalaki, E., Farber, P., Jervis, D., Fussner, E., Plochowietz, A., Craggs, T. D., Bazett-Jones, D. P., Pawson, T., Forman-Kay, J. D., et al. (2015) · Molecular Cell

RNA Research and SplicingProtein Structure and Dynamics

Cited by 1,803

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

Schulze, K., Imbeaud, S., Letouzé, E., Alexandrov, L. B., Calderaro, J., Rebouissou, S., Couchy, G., Meiller, C., Shinde, J., Soysouvanh, F., et al. (2015) · Nature Genetics

Cancer Genomics and DiagnosticsHepatocellular Carcinoma Treatment and Prognosis

Cited by 1,803

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

EPIC- InterAct Consortium, Burgess, S., Scott, R. A., Timpson, N. J., Davey Smith, G., & Thompson, S. G. (2015) · European Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 1,803

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

Tenhunen, R., Marver, H. S., & Schmid, R. (1968) · Proceedings of the National Academy of Sciences

Heme Oxygenase-1 and Carbon MonoxideNeonatal Health and Biochemistry

Cited by 1,803

How clonal are bacteria?

Smith, J. M., Smith, N. H., O'Rourke, M., & Spratt, B. G. (1993) · Proceedings of the National Academy of Sciences

Genetic diversity and population structureEvolution and Genetic Dynamics

Cited by 1,802

Meta-Analysis of BRCA1 and BRCA2 Penetrance

Chen, S., & Parmigiani, G. (2007) · Journal of Clinical Oncology

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 1,802

How Shelterin Protects Mammalian Telomeres

Palm, W., & de Lange, T. (2008) · Annual Review of Genetics

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 1,802

Abiraterone for prostate cancer not previously treated with hormone therapy

James, N. D., de Bono, J. S., Spears, M. R., Clarke, N. W., Mason, M. D., Dearnaley, D. P., Ritchie, A. W. S., Amos, C. L., Gilson, C., Jones, R. J., et al. (2017) · New England Journal of Medicine

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 1,801

Chemokine signaling via the CXCR2 receptor reinforces senescence

Acosta, J. C., O'Loghlen, A., Banito, A., Guijarro, M. V., Augert, A., Raguz, S., Fumagalli, M., Da Costa, M., Brown, C., Popov, N., et al. (2008) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,801

Delivery materials for siRNA therapeutics

Kanasty, R., Dorkin, J. R., Vegas, A., & Anderson, D. (2013) · Nature Materials

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,800

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

Walsh, T., McClellan, J. M., McCarthy, S. E., Addington, A. M., Pierce, S. B., Cooper, G. M., Nord, A. S., Kusenda, M., Malhotra, D., Bhandari, A., et al. (2008) · Science

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 1,800

Sparse and Compositionally Robust Inference of Microbial Ecological Networks

Kurtz, Z. D., Müller, C. L., Miraldi, E. R., Littman, D. R., Blaser, M. J., & Bonneau, R. A. (2015) · PLOS Computational Biology

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,799

TERT Promoter Mutations in Familial and Sporadic Melanoma

Horn, S., Figl, A., Rachakonda, P. S., Fischer, C., Sucker, A., Gast, A., Kadel, S., Moll, I., Nagore, E., Hemminki, K., et al. (2013) · Science

Melanoma and MAPK PathwaysTelomeres, Telomerase, and Senescence

Cited by 1,799

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Hangauer, M. J., Viswanathan, V. S., Ryan, M. J., Bole, D., Eaton, J. K., Matov, A., Galeas, J., Dhruv, H. D., Berens, M. E., Schreiber, S. L., et al. (2017) · Nature

Ferroptosis and cancer prognosisCancer Cells and Metastasis

Cited by 1,799

ATR: an essential regulator of genome integrity

Cimprich, K. A., & Cortez, D. (2008) · Nature Reviews Molecular Cell Biology

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,798

Role of autophagy in cancer

Mathew, R., Karantza-Wadsworth, V., & White, E. (2007) · Nature Reviews Cancer

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,798