Most cited biochemistry, genetics and molecular biology papers
- Verified
The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J., Deng, Y., Blennerhassett, P., Macri, J., McCoy, K. D., et al. (2011) · Gastroenterology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,748
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Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
Lian, X., Zhang, J., Azarin, S. M., Zhu, K., Hazeltine, L. B., Bao, X., Hsiao, C., Kamp, T. J., & Palecek, S. P. (2013) · Nature Protocols
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 1,748
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m6A RNA methylation promotes XIST-mediated transcriptional repression
Patil, D. P., Chen, C.-K., Pickering, B. F., Chow, A., Jackson, C., Guttman, M., & Jaffrey, S. R. (2016) · Nature
RNA modifications and cancerEpigenetics and DNA Methylation
Cited by 1,747
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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
Bell, A. C., & Felsenfeld, G. (2000) · Nature
Genetic Syndromes and ImprintingGenomics and Chromatin Dynamics
Cited by 1,746
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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
The Type 1 Diabetes Genetics Consortium, Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., et al. (2009) · Nature Genetics
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 1,746
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Shared and distinct transcriptomic cell types across neocortical areas
Tasic, B., Yao, Z., Graybuck, L. T., Smith, K. A., Nguyen, T. N., Bertagnolli, D., Goldy, J., Garren, E., Economo, M. N., Viswanathan, S., et al. (2018) · Nature
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 1,746
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Large recurrent microdeletions associated with schizophrenia.
GROUP, Stefansson, H., Rujescu, D., Cichon, S., Pietiläinen, O. P. H., Ingason, A., Steinberg, S., Fossdal, R., Sigurdsson, E., Sigmundsson, T., et al. (2008) · Nature
Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment
Cited by 1,745
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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., et al. (2018) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,744
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Conserved role of intragenic DNA methylation in regulating alternative promoters
Maunakea, A. K., Nagarajan, R. P., Bilenky, M., Ballinger, T. J., D’Souza, C., Fouse, S. D., Johnson, B. E., Hong, C., Nielsen, C., Zhao, Y., et al. (2010) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 1,743
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The biogenesis and emerging roles of circular RNAs
Chen, L.-L. (2016) · Nature Reviews Molecular Cell Biology
Circular RNAs in diseasesRNA Research and Splicing
Cited by 1,743
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Myotubes differentiate optimally on substrates with tissue-like stiffness
Engler, A. J., Griffin, M. A., Sen, S., Bönnemann, C. G., Sweeney, H. L., & Discher, D. E. (2004) · The Journal of Cell Biology
Cellular Mechanics and InteractionsMuscle Physiology and Disorders
Cited by 1,743
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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
Weinberg, F., Hamanaka, R., Wheaton, W. W., Weinberg, S., Joseph, J., Lopez, M., Kalyanaraman, B., Mutlu, G. M., Budinger, G. R. S., & Chandel, N. S. (2010) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology
Cited by 1,742
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Shedding microvesicles: artefacts no more
Cocucci, E., Racchetti, G., & Meldolesi, J. (2009) · Trends in Cell Biology
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 1,742
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Natural hybridization and evolution
Arnold, M. L. (1997) · Choice Reviews Online
Chromosomal and Genetic VariationsEvolution and Genetic Dynamics
Cited by 1,742
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The Protective Role of Melanin Against UV Damage in Human Skin †
Brenner, M., & Hearing, V. J. (2008) · Photochemistry and Photobiology
melanin and skin pigmentationSkin Protection and Aging
Cited by 1,741
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Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
Yan, L., Yang, M., Guo, H., Yang, L., Wu, J., Li, R., Liu, P., Lian, Y., Zheng, X., Yan, J., et al. (2013) · Nature Structural & Molecular Biology
Single-cell and spatial transcriptomicsPluripotent Stem Cells Research
Cited by 1,740
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Role of microorganisms in the evolution of animals and plants: the hologenome theory of evolution
Zilber-Rosenberg, I., & Rosenberg, E. (2008) · FEMS Microbiology Reviews
Evolution and Genetic DynamicsInsect symbiosis and bacterial influences
Cited by 1,739
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The Cytolytic P 2Z Receptor for Extracellular ATP Identified as a P 2X Receptor (P2X 7 )
Surprenant, A., Rassendren, F., Kawashima, E., North, R. A., & Buell, G. (1996) · Science
Adenosine and Purinergic SignalingCalcium signaling and nucleotide metabolism
Cited by 1,739
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Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly
Nakayama, J.-I., Rice, J. C., Strahl, B. D., Allis, C. D., & Grewal, S. I. S. (2001) · Science
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,739
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The mononuclear molybdenum enzymes
Hille, R., Hall, J., & Basu, P. (2014) · Chemical Reviews
Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms
Cited by 1,738
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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
Howie, B., Fuchsberger, C., Stephens, M., Marchini, J., & Abecasis, G. R. (2012) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,737
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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
Sottoriva, A., Spiteri, I., Piccirillo, S. G. M., Touloumis, A., Collins, V. P., Marioni, J. C., Curtis, C., Watts, C., & Tavaré, S. (2013) · Proceedings of the National Academy of Sciences
Cancer Genomics and DiagnosticsGlioma Diagnosis and Treatment
Cited by 1,737
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Stochastic mRNA Synthesis in Mammalian Cells
Raj, A., Peskin, C. S., Tranchina, D., Vargas, D. Y., & Tyagi, S. (2006) · PLoS Biology
Gene Regulatory Network Analysisstochastic dynamics and bifurcation
Cited by 1,737
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Oxidative Nucleobase Modifications Leading to Strand Scission
Burrows, C. J., & Muller, J. G. (1998) · Chemical Reviews
DNA and Nucleic Acid ChemistryDNA Repair Mechanisms
Cited by 1,736
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