Most cited biochemistry, genetics and molecular biology papers
- Verified
NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder
Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., & Tschopp, J. (2004) · Immunity
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,768
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Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases
Beurel, E., Grieco, S. F., & Jope, R. S. (2015) · Pharmacology & Therapeutics
Wnt/β-catenin signaling in development and cancerProtein Kinase Regulation and GTPase Signaling
Cited by 1,768
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A single–cell type transcriptomics map of human tissues
Karlsson, M., Zhang, C., Méar, L., Zhong, W., Digre, A., Katona, B., Sjöstedt, E., Butler, L., Odeberg, J., Dusart, P., et al. (2021) · Science Advances
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,768
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Human mesenchymal stem cells modulate B-cell functions
Corcione, A., Benvenuto, F., Ferretti, E., Giunti, D., Cappiello, V., Cazzanti, F., Risso, M., Gualandi, F., Mancardi, G. L., Pistoia, V., et al. (2006) · Blood
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 1,767
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Therapeutic Approaches to Bone Diseases
Rodan, G. A., & Martin, T. J. (2000) · Science
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,767
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The emerging mechanisms of isoform-specific PI3K signalling
Vanhaesebroeck, B., Guillermet-Guibert, J., Graupera, M., & Bilanges, B. (2010) · Nature Reviews Molecular Cell Biology
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,767
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Senescence in Health and Disease
He, S., & Sharpless, N. E. (2017) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,766
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The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
Altshuler, D., Hirschhorn, J. N., Klannemark, M., Lindgren, C. M., Vohl, M.-C., Nemesh, J., Lane, C. R., Schaffner, S. F., Bolk, S., Brewer, C., et al. (2000) · Nature Genetics
Peroxisome Proliferator-Activated ReceptorsGenetic Associations and Epidemiology
Cited by 1,766
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Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability
Peters, A. H. F. M., O'Carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., et al. (2001) · Cell
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,766
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X chromosome-linked muscular dystrophy (mdx) in the mouse
Bulfield, G., Siller, W. G., Wight, P. A., & Moore, K. J. (1984) · Proceedings of the National Academy of Sciences
Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research
Cited by 1,765
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Identifying differentially expressed genes using false discovery rate controlling procedures
Reiner, A., Yekutieli, D., & Benjamini, Y. (2003) · Bioinformatics
Gene expression and cancer classificationStatistical Methods in Clinical Trials
Cited by 1,765
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MicroRNA profiling: approaches and considerations
Pritchard, C. C., Cheng, H. H., & Tewari, M. (2012) · Nature Reviews Genetics
MicroRNA in disease regulationGene expression and cancer classification
Cited by 1,765
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Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations
Hyman, D. M., Puzanov, I., Subbiah, V., Faris, J. E., Chau, I., Blay, J.-Y., Wolf, J., Raje, N. S., Diamond, E. L., Hollebecque, A., et al. (2015) · New England Journal of Medicine
Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations
Cited by 1,764
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Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
Finley, D. (2009) · Annual Review of Biochemistry
Ubiquitin and proteasome pathwaysHeat shock proteins research
Cited by 1,764
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JASPAR 2020: update of the open-access database of transcription factor binding profiles
Fornes, O., Castro-Mondragon, J. A., Khan, A., van der Lee, R., Zhang, X., Richmond, P. A., Modi, B. P., Correard, S., Gheorghe, M., Baranašić, D., et al. (2019) · Nucleic Acids Research
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 1,763
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WNT and β-catenin signalling: diseases and therapies
Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics
Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies
Cited by 1,763
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A germline-specific class of small RNAs binds mammalian Piwi proteins
Girard, A., Sachidanandam, R., Hannon, G. J., & Carmell, M. A. (2006) · Nature
RNA Interference and Gene DeliveryChromosomal and Genetic Variations
Cited by 1,762
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MEGAN Community Edition - Interactive Exploration and Analysis of Large-Scale Microbiome Sequencing Data
Huson, D. H., Beier, S., Flade, I., Górska, A., El-Hadidi, M., Mitra, S., Ruscheweyh, H.-J., & Tappu, R. (2016) · PLOS Computational Biology
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 1,761
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Association between telomere length in blood and mortality in people aged 60 years or older
Cawthon, R. M., Smith, K. R., O'Brien, E., Sivatchenko, A., & Kerber, R. A. (2003) · The Lancet
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,761
- Verified
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
The MAGIC investigators, Voight, B. F., The GIANT Consortium, Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., et al. (2010) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,761
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Genesis: cluster analysis of microarray data
Sturn, A., Quackenbush, J., & Trajanoski, Z. (2002) · Bioinformatics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 1,761
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Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues
Baker, B. M., & Chen, C. S. (2012) · Journal of Cell Science
Cellular Mechanics and Interactions3D Printing in Biomedical Research
Cited by 1,760
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Phthalimide conjugation as a strategy for in vivo target protein degradation
Winter, G. E., Buckley, D. L., Paulk, J., Roberts, J. M., Souza, A., Dhe-Paganon, S., & Bradner, J. E. (2015) · Science
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 1,760
- Verified
Cooler: scalable storage for Hi-C data and other genomically labeled arrays
Abdennur, N., & Mirny, L. A. (2020) · Bioinformatics
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 1,759
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