Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

A Randomized Trial of Exemestane after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer

Coombes, R. C., Hall, E., Gibson, L. J., Paridaens, R., Jassem, J., Delozier, T., Jones, S. E., Alvarez, I., Bertelli, G., Ortmann, O., et al. (2004) · New England Journal of Medicine

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 1,759

Skeletal muscle: A brief review of structure and function

Frontera, W. R., & Ochala, J. (2015) · Calcified Tissue International

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 1,758

Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

Phiel, C. J., Zhang, F., Huang, E. Y., Guenther, M. G., Lazar, M. A., & Klein, P. S. (2001) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchPharmacological Effects and Toxicity Studies

Cited by 1,758

Non-homologous DNA end joining and alternative pathways to double-strand break repair

Chang, H. H. Y., Pannunzio, N. R., Adachi, N., & Lieber, M. R. (2017) · Nature Reviews Molecular Cell Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,757

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

Davydov, E. V., Goode, D. L., Sirota, M., Cooper, G. M., Sidow, A., & Batzoglou, S. (2010) · PLoS Computational Biology

Genomics and Phylogenetic StudiesGenomics and Chromatin Dynamics

Cited by 1,757

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR

Haeussler, M., Schönig, K., Eckert, H., Eschstruth, A., Mianné, J., Renaud, J.-B., Schneider-Maunoury, S., Shkumatava, A., Teboul, L., Kent, J., et al. (2016) · Genome biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,756

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

Chen, G., Deng, C., & Li, Y.-P. (2012) · International Journal of Biological Sciences

Bone Metabolism and DiseasesTGF-β signaling in diseases

Cited by 1,756

IAP proteins: blocking the road to death's door

Salvesen, G. S., & Duckett, C. S. (2002) · Nature Reviews Molecular Cell Biology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,756

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

Frank, S., Gaume, B., Bergmann-Leitner, E. S., Leitner, W. W., Robert, E. G., Catez, F., Smith, C. L., & Youle, R. J. (2001) · Developmental Cell

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 1,755

The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

Mariat, D., Firmesse, O., Levenez, F., Guimarăes, V., Sokol, H., Doré, J., Corthier, G., & Furet, J.-P. (2009) · BMC Microbiology

Gut microbiota and healthInfant Nutrition and Health

Cited by 1,755

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH

Eng, C.-H. L., Lawson, M., Zhu, Q., Dries, R., Koulena, N., Takei, Y., Yun, J., Cronin, C., Karp, C., Yuan, G.-C., et al. (2019) · Nature

Single-cell and spatial transcriptomicsAdvanced Fluorescence Microscopy Techniques

Cited by 1,754

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

Gold, L., Ayers, D., Bertino, J., Bock, C., Bock, A., Brody, E. N., Carter, J., Dalby, A. B., Eaton, B. E., Fitzwater, T., et al. (2010) · PLoS ONE

Advanced biosensing and bioanalysis techniquesAdvanced Biosensing Techniques and Applications

Cited by 1,754

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

Yu, Q., & Stamenkovic, I. (2000) · Genes & Development

Protease and Inhibitor MechanismsTGF-β signaling in diseases

Cited by 1,754

Composition, variability, and temporal stability of the intestinal microbiota of the elderly

Claesson, M. J., Cusack, S., O'Sullivan, O., Greene-Diniz, R., de Weerd, H., Flannery, E., Marchesi, J. R., Falush, D., Dinan, T., Fitzgerald, G., et al. (2011) · Proceedings of the National Academy of Sciences

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,754

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

Weinstein, R. S., Jilka, R. L., Parfitt, A. M., & Manolagas, S. C. (1998) · Journal of Clinical Investigation

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,753

A Phase Separation Model for Transcriptional Control

Hnisz, D., Shrinivas, K., Young, R. A., Chakraborty, A. K., & Sharp, P. A. (2017) · Cell

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 1,753

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Mali, P., Aach, J., Stranges, P. B., Esvelt, K. M., Moosburner, M., Kosuri, S., Yang, L., & Church, G. M. (2013) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,752

Estimating cumulative point prevalence of rare diseases: analysis of the Orphanet database

Nguengang Wakap, S., Lambert, D. M., Olry, A., Rodwell, C., Gueydan, C., Lanneau, V., Murphy, D., Le Cam, Y., & Rath, A. (2020) · European Journal of Human Genetics

Genomics and Rare DiseasesConnective tissue disorders research

Cited by 1,752

Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1

Semenza, G. L., Jiang, B.-H., Leung, S. W., Passantino, R., Concordet, J.-P., Maire, P., & Giallongo, A. (1996) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 1,752

Reactome: a database of reactions, pathways and biological processes

Croft, D., O'Kelly, G., Wu, G., Haw, R., Gillespie, M., Matthews, L., Caudy, M., Garapati, P., Gopinath, G., Jassal, B., et al. (2011) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 1,751

The mechanisms of Hedgehog signalling and its roles in development and disease

Briscoe, J., & Thérond, P. P. (2013) · Nature Reviews Molecular Cell Biology

Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases

Cited by 1,751

Calculating statistical power in Mendelian randomization studies.

Brion, M.-J. A., Shakhbazov, K., & Visscher, P. M. (2013) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 1,751

A single-cell survey of the small intestinal epithelium

Haber, A. L., Biton, M., Rogel, N., Herbst, R. H., Shekhar, K., Smillie, C., Burgin, G., Delorey, T. M., Howitt, M. R., Katz, Y., et al. (2017) · Nature

Single-cell and spatial transcriptomicsIL-33, ST2, and ILC Pathways

Cited by 1,750

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database

Rawlings, N. D., Barrett, A. J., Thomas, P. D., Huang, X., Bateman, A., & Finn, R. D. (2018) · Nucleic Acids Research

Protease and Inhibitor MechanismsGenomics and Phylogenetic Studies

Cited by 1,749