Most cited biochemistry, genetics and molecular biology papers
- Verified
Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function
Kelly, C. J., Zheng, L., Campbell, E. L., Saeedi, B., Scholz, C. C., Bayless, A. J., Wilson, K. E., Glover, L. E., Kominsky, D. J., Magnuson, A., et al. (2015) · Cell Host & Microbe
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,716
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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
Finnin, M. S., Donigian, J. R., Cohen, A., Richon, V. M., Rifkind, R. A., Marks, P. A., Breslow, R., & Pavletich, N. P. (1999) · Nature
Histone Deacetylase Inhibitors ResearchEnzyme Structure and Function
Cited by 1,714
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Adult mouse cortical cell taxonomy revealed by single cell transcriptomics
Tasic, B., Menon, V., Nguyen, T. N., Kim, T. K., Jarsky, T., Yao, Z., Levi, B., Gray, L. T., Sorensen, S. A., Dolbeare, T., et al. (2016) · Nature Neuroscience
Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research
Cited by 1,714
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Cancer Susceptibility and the Functions of BRCA1 and BRCA2
Venkitaraman, A. R. (2002) · Cell
BRCA gene mutations in cancerDNA Repair Mechanisms
Cited by 1,713
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Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Yang, J., DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Ferreira, T., Morris, A. P., Medland, S. E., Madden, P. A. F., Heath, A. C., Martin, N. G., Montgomery, G. W., et al. (2012) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,712
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ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
Wiegand, K. C., Shah, S. P., Al-Agha, O. M., Zhao, Y., Tse, K., Zeng, T., Senz, J., McConechy, M. K., Anglesio, M. S., Kalloger, S. E., et al. (2010) · New England Journal of Medicine
Chromatin Remodeling and CancerOvarian cancer diagnosis and treatment
Cited by 1,712
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Identification of the haemoglobin scavenger receptor
Kristiansen, M., Graversen, J. H., Jacobsen, C., Sonne, O., Hoffman, H.-J., Law, S. K. A., & Moestrup, S. K. (2001) · Nature
Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide
Cited by 1,712
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Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
Semenza, G. L. (2010) · Oncogene
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 1,712
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The p66shc adaptor protein controls oxidative stress response and life span in mammals
Migliaccio, E., Giorgio, M., Mele, S., Pelicci, G., Reboldi, P., Pandolfi, P. P., Lanfrancone, L., & Pelicci, P. G. (1999) · Nature
Genetics, Aging, and Longevity in Model OrganismsCell death mechanisms and regulation
Cited by 1,712
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Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
Bardia, A., Hurvitz, S. A., Tolaney, S. M., Loirat, D., Punie, K., Oliveira, M., Brufsky, A., Sardesai, S. D., Kalinsky, K., Zelnak, A. B., et al. (2021) · New England Journal of Medicine
Breast Cancer Treatment StudiesCancer Treatment and Pharmacology
Cited by 1,711
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THE EVOLUTIONARY ADVANTAGE OF RECOMBINATION
Felsenstein, J. (1974) · Genetics
Evolution and Genetic DynamicsPhilosophy of Biology and Scientific Explanation
Cited by 1,711
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Men and mice: Relating their ages
Dutta, S., & Sengupta, P. (2016) · Life Sciences
Genetics, Aging, and Longevity in Model OrganismsAnimal testing and alternatives
Cited by 1,710
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Dysbiosis of the gut microbiota in disease
Carding, S., Verbeke, K., Vipond, D. T., Corfe, B. M., & Owen, L. J. (2015) · Microbial Ecology in Health & Disease
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,710
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Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization
Nora, E. P., Goloborodko, A., Valton, A.-L., Gibcus, J. H., Uebersohn, A., Abdennur, N., Dekker, J., Mirny, L. A., & Bruneau, B. G. (2017) · Cell
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,709
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TRF2 Protects Human Telomeres from End-to-End Fusions
van Steensel, B., Smogorzewska, A., & de Lange, T. (1998) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,709
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Reconstitution of I KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor
Inagaki, N., Gonoi, T., Clement, J. P., Namba, N., Inazawa, J., Gonzalez, G., Aguilar-Bryan, L., Seino, S., & Bryan, J. (1995) · Science
Ion channel regulation and functionPancreatic function and diabetes
Cited by 1,709
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A conditional knockout resource for the genome-wide study of mouse gene function
Skarnes, W. C., Rosen, B., West, A. P., Koutsourakis, M., Bushell, W., Iyer, V., Mujica, A. O., Thomas, M., Harrow, J., Cox, T., et al. (2011) · Nature
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 1,708
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Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH
Zhu, L., Baker, S. S., Gill, C., Liu, W., Alkhouri, R., Baker, R. D., & Gill, S. R. (2013) · Hepatology
Gut microbiota and healthLiver Disease Diagnosis and Treatment
Cited by 1,708
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Cellular senescence in cancer and aging.
Collado, M., Blasco, M. A., & Serrano, M. (2007) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,708
- Verified
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Denko, N. C. (2008) · Nature Reviews Cancer
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,707
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Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
Maines, M. D. (1988) · The FASEB Journal
Heme Oxygenase-1 and Carbon MonoxidePorphyrin Metabolism and Disorders
Cited by 1,707
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SUnSET, a nonradioactive method to monitor protein synthesis
Schmidt, E. K., Clavarino, G., Ceppi, M., & Pierre, P. (2009) · Nature Methods
RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 1,706
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The DNA Damage Response: Ten Years After
Harper, J. W., & Elledge, S. J. (2007) · Molecular Cell
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,705
- Verified
CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning
Chklovski, A., Parks, D. H., Woodcroft, B. J., & Tyson, G. W. (2023) · Nature Methods
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 1,705
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