Most cited biochemistry, genetics and molecular biology papers
- Verified
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
Berghe, T. V., Linkermann, A., Jouan-Lanhouet, S., Walczak, H., & Vandenabeele, P. (2014) · Nature Reviews Molecular Cell Biology
Cell death mechanisms and regulationFerroptosis and cancer prognosis
Cited by 1,735
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Mitochondria and cancer
Vyas, S., Zaganjor, E., & Haigis, M. C. (2016) · Cell
Mitochondrial Function and PathologyCancer, Hypoxia, and Metabolism
Cited by 1,735
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Leptin Regulates Bone Formation via the Sympathetic Nervous System
Takeda, S., Elefteriou, F., Levasseur, R., Liu, X., Zhao, L., Parker, K. L., Armstrong, D., Ducy, P., & Karsenty, G. (2002) · Cell
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,735
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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
Collinge, J., Sidle, K. C. L., Meads, J., Ironside, J., & Hill, A. F. (1996) · Nature
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 1,735
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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
Gomes, L. C., Benedetto, G. D., & Scorrano, L. (2011) · Nature Cell Biology
Autophagy in Disease and TherapyMitochondrial Function and Pathology
Cited by 1,735
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Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Sies, H., Belousov, V. V., Chandel, N. S., Davies, M. J., Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M., & Winterbourn, C. (2022) · Nature Reviews Molecular Cell Biology
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,735
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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
Jiang, J., & Struhl, G. (1998) · Nature
Hedgehog Signaling Pathway StudiesWnt/β-catenin signaling in development and cancer
Cited by 1,735
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Glutathione and its role in cellular functions
Sies, H. (1999) · Free Radical Biology and Medicine
Sulfur Compounds in BiologyRedox biology and oxidative stress
Cited by 1,735
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Empirical Bayes analysis of a microarray experiment
Efron, B., Tibshirani, R., Storey, J. D., & Tusher, V. (2001) · Journal of the American Statistical Association
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 1,733
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Ultraconserved Elements in the Human Genome
Bejerano, G., Pheasant, M., Makunin, I., Stephen, S., Kent, W. J., Mattick, J. S., & Haussler, D. (2004) · Science
Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies
Cited by 1,732
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Structure and ligand of a histone acetyltransferase bromodomain
Dhalluin, C., Carlson, J. E., Zeng, L., He, C., Aggarwal, A. K., Zhou, M.-M., & Zhou, M.-M. (1999) · Nature
Genomics and Chromatin DynamicsProtein Degradation and Inhibitors
Cited by 1,732
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Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella
Kovatcheva-Datchary, P., Nilsson, A., Akrami, R., Lee, Y. S., De Vadder, F., Arora, T., Hallen, A., Martens, E., Björck, I., & Bäckhed, F. (2015) · Cell Metabolism
Gut microbiota and healthFood composition and properties
Cited by 1,731
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Intrinsic Disorder and Protein Function
Dunker, A. K., Brown, C. J., Lawson, J. D., Iakoucheva, L. M., & Obradović, Z. (2002) · Biochemistry
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 1,731
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Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander, O. P. B., Nordin, J. Z., O'Loughlin, A., Gustafsson, Y., Corso, G., Mäger, I., Vader, P., Lee, Y., Sork, H., Seow, Y., et al. (2015) · Journal of Extracellular Vesicles
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 1,730
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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
Sanborn, A. L., Rao, S. S. P., Huang, S.-C., Durand, N. C., Huntley, M. H., Jewett, A. I., Bochkov, I. D., Chinnappan, D., Cutkosky, A., Li, J., et al. (2015) · Proceedings of the National Academy of Sciences
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,730
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High frequency of BRAF mutations in nevi
Pollock, P. M., Harper, U. L., Hansen, K. S., Yudt, L. M., Stark, M., Robbins, C. M., Moses, T. Y., Hostetter, G., Wagner, U., Kakareka, J., et al. (2003) · Nature Genetics
Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management
Cited by 1,730
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Diet-induced extinctions in the gut microbiota compound over generations
Sonnenburg, E. D., Smits, S. A., Tikhonov, M., Higginbottom, S. K., Wingreen, N. S., & Sonnenburg, J. L. (2016) · Nature
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,730
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Efficient differentiation of human embryonic stem cells to definitive endoderm
D'Amour, K. A., Agulnick, A. D., Eliazer, S., Kelly, O. G., Kroon, E., & Baetge, E. E. (2005) · Nature Biotechnology
Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation
Cited by 1,730
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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
Krtolica, A., Parrinello, S., Lockett, S., Desprez, P.-Y., & Campisi, J. (2001) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,730
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Bacteria and archaea on Earth and their abundance in biofilms
Flemming, H.-C., & Wuertz, S. (2019) · Nature Reviews Microbiology
Bacterial biofilms and quorum sensingMicrobial Community Ecology and Physiology
Cited by 1,729
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Cells of the adult human heart
Litviňuková, M., Talavera-López, C., Maatz, H., Reichart, D., Worth, C. L., Lindberg, E. L., Kanda, M., Polanski, K., Heinig, M., Lee, M., et al. (2020) · Nature
Single-cell and spatial transcriptomicsCongenital heart defects research
Cited by 1,729
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Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
Tournier, C., Hess, P., Yang, D. D., Xu, J., Turner, T. K., Nimnual, A., Bar-Sagi, D., Jones, S. N., Flavell, R. A., & Davis, R. J. (2000) · Science
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,728
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Predicting Changes in the Stability of Proteins and Protein Complexes: A Study of More Than 1000 Mutations
Guerois, R., Nielsen, J. E., & Serrano, L. (2002) · Journal of Molecular Biology
Protein Structure and DynamicsRNA and protein synthesis mechanisms
Cited by 1,728
- Verified
A genomic mutational constraint map using variation in 76,156 human genomes
Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., et al. (2024) · Nature
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 1,727
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