Most cited biochemistry, genetics and molecular biology papers
- Verified
Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder
Chen, Q., Yan, M., Cao, Z., Li, X., Zhang, Y., Shi, J., Feng, G.-H., Peng, H., Zhang, X., Zhang, Y., et al. (2016) · Science
RNA modifications and cancerSperm and Testicular Function
Cited by 1,470
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Interdependence of Cell Growth and Gene Expression: Origins and Consequences
Scott, M., Gunderson, C. W., Mateescu, E. M., Zhang, Z., & Hwa, T. (2010) · Science
Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology
Cited by 1,470
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Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions
Burton, J. N., Adey, A., Patwardhan, R. P., Qiu, R., Kitzman, J. O., & Shendure, J. (2013) · Nature Biotechnology
Genomics and Phylogenetic StudiesGenomics and Chromatin Dynamics
Cited by 1,470
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Antibiotics, birth mode, and diet shape microbiome maturation during early life
Bokulich, N. A., Chung, J., Battaglia, T., Henderson, N., Jay, M., Li, H., D. Lieber, A., Wu, F., Perez-Perez, G. I., Chen, Y., et al. (2016) · Science Translational Medicine
Gut microbiota and healthInfant Nutrition and Health
Cited by 1,469
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Lysosomes as dynamic regulators of cell and organismal homeostasis
Ballabio, A., & Bonifacino, J. S. (2020) · Nature Reviews Molecular Cell Biology
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 1,469
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General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
Wang, G. L., & Semenza, G. L. (1993) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,468
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Real-Time Kinetics of Gene Activity in Individual Bacteria
Golding, I., Paulsson, J., Zawilski, S. M., & Cox, E. C. (2005) · Cell
Gene Regulatory Network AnalysisBacterial Genetics and Biotechnology
Cited by 1,468
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Comprehensive human genome amplification using multiple displacement amplification
Dean, F. B., Hosono, S., Fang, L., Wu, X., Faruqi, A. F., Bray-Ward, P., Sun, Z., Zong, Q., Du, Y., Du, J., et al. (2002) · Proceedings of the National Academy of Sciences
Molecular Biology Techniques and ApplicationsGenomics and Phylogenetic Studies
Cited by 1,467
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Ras oncogenes: split personalities
Karnoub, A. E., & Weinberg, R. A. (2008) · Nature Reviews Molecular Cell Biology
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 1,467
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Targeting the TGFβ signalling pathway in disease
Akhurst, R. J., & Hata, A. (2012) · Nature Reviews Drug Discovery
TGF-β signaling in diseasesConnective tissue disorders research
Cited by 1,466
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Large-scale analysis of the human and mouse transcriptomes
Su, A. I., Cooke, M. P., Ching, K. A., Hakak, Y., Walker, J. R., Wiltshire, T., Orth, A. P., Vega, R. G., Sapinoso, L. M., Moqrich, A., et al. (2002) · Proceedings of the National Academy of Sciences
Bioinformatics and Genomic NetworksGene expression and cancer classification
Cited by 1,466
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The human keratins: biology and pathology
Moll, R., Divo, M., & Langbein, L. (2008) · Histochemistry and Cell Biology
Skin and Cellular Biology ResearchNuclear Structure and Function
Cited by 1,465
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A Controlled Trial of Leuprolide with and without Flutamide in Prostatic Carcinoma
Crawford, E. D., Eisenberger, M. A., McLeod, D. G., Spaulding, J. T., Benson, R., Dorr, F. A., Blumenstein, B. A., Davis, M. A., & Goodman, P. J. (1989) · New England Journal of Medicine
Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment
Cited by 1,464
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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
Rushmore, T. H., Morton, M. R., & Pickett, C. B. (1991) · Journal of Biological Chemistry
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 1,464
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Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators
McKenna, N. J., & O'Malley, B. W. (2002) · Cell
Estrogen and related hormone effectsNuclear Receptors and Signaling
Cited by 1,463
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Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
Luo, W., Hu, H., Chang, R., Zhong, J., Knabel, M., O'Meally, R., Cole, R. N., Pandey, A., & Semenza, G. L. (2011) · Cell
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,463
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Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
Terwilliger, T. C., Grosse-Kunstleve, R. W., Afonine, P. V., Moriarty, N. W., Zwart, P. H., Hung, L.-W., Read, R. J., & Adams, P. D. (2008) · Acta Crystallographica Section D Biological Crystallography
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 1,462
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Proteogenomic characterization of human colon and rectal cancer
CPTAC, T. N., Zhang, B., Wang, J., Wang, X., Zhu, J., Liu, Q., Shi, Z., Chambers, M. C., Zimmerman, L. J., Shaddox, K. F., et al. (2014) · Nature
Cancer Genomics and DiagnosticsAdvanced Proteomics Techniques and Applications
Cited by 1,462
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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Ho, P.-C., Bihuniak, J. D., Macintyre, A. N., Staron, M., Liu, X., Amezquita, R., Tsui, Y.-C., Cui, G., Micevic, G., Perales, J. C., et al. (2015) · Cell
Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers
Cited by 1,462
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Mechanobiology of YAP and TAZ in physiology and disease
Panciera, T., Azzolin, L., Cordenonsi, M., & Piccolo, S. (2017) · Nature Reviews Molecular Cell Biology
Hippo pathway signaling and YAP/TAZCellular Mechanics and Interactions
Cited by 1,461
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Direct detection of DNA methylation during single-molecule, real-time sequencing
Flusberg, B. A., Webster, D. R., Lee, J. H., Travers, K. J., Olivares, E. C., Clark, T. A., Korlach, J., & Turner, S. W. (2010) · Nature Methods
Epigenetics and DNA MethylationDNA and Nucleic Acid Chemistry
Cited by 1,460
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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
Zuris, J. A., Thompson, D. B., Shu, Y., Guilinger, J. P., Bessen, J. L., Hu, J. H., Maeder, M. L., Joung, J. K., Chen, Z.-Y., & Liu, D. R. (2015) · Nature Biotechnology
RNA Interference and Gene DeliveryCRISPR and Genetic Engineering
Cited by 1,460
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Integrative single-cell analysis
Stuart, T., & Satija, R. (2019) · Nature Reviews Genetics
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 1,460
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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
Johannessen, C. M., Boehm, J. S., Kim, S. Y., Thomas, S. R., Wardwell, L., Johnson, L. A., Emery, C. M., Stransky, N., Cogdill, A. P., Barretina, J., et al. (2010) · Nature
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 1,460
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