Most cited biochemistry, genetics and molecular biology papers
- Verified
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease
Khera, A. V., Emdin, C. A., Drake, I., Natarajan, P., Bick, A. G., Cook, N. R., Chasman, D. I., Baber, U., Mehran, R., Rader, D. J., et al. (2016) · New England Journal of Medicine
Genetic Associations and EpidemiologyNutrition, Genetics, and Disease
Cited by 1,460
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Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells
Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., & Livingston, D. M. (1997) · Cell
DNA Repair MechanismsBRCA gene mutations in cancer
Cited by 1,459
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p53 mutant mice that display early ageing-associated phenotypes
Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X., Soron, G., Cooper, B., Brayton, C., et al. (2002) · Nature
Genetics, Aging, and Longevity in Model OrganismsCancer-related Molecular Pathways
Cited by 1,459
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The next generation of CRISPR–Cas technologies and applications
Pickar-Oliver, A., & Gersbach, C. A. (2019) · Nature Reviews Molecular Cell Biology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,459
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Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
Li, J., & Ji, L. (2005) · Heredity
Genetic Associations and EpidemiologyStatistical Methods in Clinical Trials
Cited by 1,458
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Coding-Sequence Determinants of Gene Expression in Escherichia coli
Kudla, G., Murray, A. W., Tollervey, D., & Plotkin, J. B. (2009) · Science
RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology
Cited by 1,458
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Modification of Enhancer Chromatin: What, How, and Why?
Calo, E., & Wysocka, J. (2013) · Molecular Cell
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 1,457
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Chromosomal rearrangements and speciation
Rieseberg, L. H. (2001) · Trends in Ecology & Evolution
Chromosomal and Genetic VariationsEvolution and Genetic Dynamics
Cited by 1,457
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Reversal of human cellular senescence: roles of the p53 and p16 pathways
Beauséjour, C. M., Krtolica, A., Galimi, F., Narita, M., Lowe, S. W., Yaswen, P., & Campisi, J. (2003) · The EMBO Journal
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 1,457
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Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
Foust, K. D., Nurre, E., Montgomery, C. L., Hernandez, A., Chan, C. M., & Kaspar, B. K. (2009) · Nature Biotechnology
Virus-based gene therapy researchBarrier Structure and Function Studies
Cited by 1,456
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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
Finland, G. O. T. 1. D. I., Todd, J. A., the Wellcome Trust Case Control Consortium, Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., et al. (2007) · Nature Genetics
Diabetes and associated disordersGenetic Associations and Epidemiology
Cited by 1,456
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Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis
Gregoretti, I., Lee, Y.-M., & Goodson, H. V. (2004) · Journal of Molecular Biology
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 1,456
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
Poulikakos, P. I., Persaud, Y., Janakiraman, M., Kong, X., Ng, C., Moriceau, G., Shi, H., Atefi, M., Titz, B., Gabay, M. T., et al. (2011) · Nature
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 1,454
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Akt Stimulates Aerobic Glycolysis in Cancer Cells
Elstrom, R. L., Bauer, D. E., Buzzai, M., Karnauskas, R., Harris, M. H., Plas, D. R., Zhuang, H., Cinalli, R. M., Alavi, A., Rudin, C. M., et al. (2004) · Cancer Research
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,454
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Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
Robertson, G., Hirst, M., Bainbridge, M., Bilenky, M., Zhao, Y., Zeng, T., Euskirchen, G., Bernier, B., Varhol, R., Delaney, A., et al. (2007) · Nature Methods
Genomics and Chromatin Dynamicsinterferon and immune responses
Cited by 1,454
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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Baar, M. P., Brandt, R. M. C., Putavet, D. A., Klein, J. D. D., Derks, K. W. J., Bourgeois, B. R. M., Stryeck, S., Rijksen, Y., van Willigenburg, H., Feijtel, D. A., et al. (2017) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,454
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Lactate metabolism in human health and disease
Li, X., Yang, Y., Zhang, B., Lin, X., Fu, X., An, Y., Zou, Y., Wang, J.-X., Wang, Z., & Yu, T. (2022) · Signal Transduction and Targeted Therapy
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,454
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Engineering cell shape and function
Singhvi, R., Kumar, A., Lopez, G. P., Stephanopoulos, G. N., Wang, D. I. C., Whitesides, G. M., & Ingber, D. E. (1994) · Science
Cellular Mechanics and InteractionsNanofabrication and Lithography Techniques
Cited by 1,453
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Autophagic cell death: the story of a misnomer
Kroemer, G., & Levine, B. (2008) · Nature Reviews Molecular Cell Biology
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 1,453
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Endogenous DNA damage as a source of genomic instability in cancer
Tubbs, A., & Nussenzweig, A. (2017) · Cell
DNA Repair MechanismsCancer Genomics and Diagnostics
Cited by 1,452
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The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses
Gaboriau-Routhiau, V., Rakotobe, S., Lécuyer, E., Mulder, I., Lan, A., Bridonneau, C., Rochet, V., Pisi, A., De Paepe, M., Brandi, G., et al. (2009) · Immunity
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 1,452
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Genetic Mapping in Human Disease
Altshuler, D., Daly, M. J., & Lander, E. S. (2008) · Science
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,452
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Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications
Wang, Y., Chen, X., Cao, W., & Shi, Y. (2014) · Nature Immunology
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 1,452
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Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner
Blanchette, M., Kent, W. J., Riemer, C., Elnitski, L., Smit, A. F. A., Roskin, K. M., Baertsch, R., Rosenbloom, K., Clawson, H., Green, E. D., et al. (2004) · Genome Research
Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms
Cited by 1,452
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