Most cited biochemistry, genetics and molecular biology papers
- Verified
Orthologs, Paralogs, and Evolutionary Genomics
Koonin, E. V. (2005) · Annual Review of Genetics
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 1,323
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PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Chen, Y., & Dorn, G. W. (2013) · Science
Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments
Cited by 1,323
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Neural mechanisms of ageing and cognitive decline
Bishop, N. A., Lu, T., & Yankner, B. A. (2010) · Nature
Genetics, Aging, and Longevity in Model OrganismsDementia and Cognitive Impairment Research
Cited by 1,323
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Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications
Zhang, Y., Bi, J., Huang, J., Tang, Y., Du, S., & Li, P. (2020) · International Journal of Nanomedicine
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 1,323
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NFAT Signaling
Crabtree, G. R., & Olson, E. N. (2002) · Cell
Signaling Pathways in DiseaseNuclear Receptors and Signaling
Cited by 1,323
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mTOR and cancer: insights into a complex relationship
Sabatini, D. M. (2006) · Nature Reviews Cancer
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,322
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Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
Cai, Z., Jitkaew, S., Zhao, J., Chiang, H.-C., Choksi, S., Liu, J., Ward, Y., Wu, L.-G., & Liu, Z.-G. (2014) · Nature Cell Biology
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 1,322
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Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction
Thevaranjan, N., Puchta, A., Schulz, C., Naidoo, A., Szamosi, J. C., Verschoor, C. P., Loukov, D., Schenck, L. P., Jury, J., Foley, K. P., et al. (2017) · Cell Host & Microbe
Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms
Cited by 1,322
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Base Excision Repair
Krokan, H. E., & Bjoras, M. (2013) · Cold Spring Harbor Perspectives in Biology
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 1,322
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RNA regulons: coordination of post-transcriptional events
Keene, J. D. (2007) · Nature Reviews Genetics
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 1,321
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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
Stambolic, V., Ruel, L., & Woodgett, J. R. (1996) · Current Biology
Wnt/β-catenin signaling in development and cancerProtein Kinase Regulation and GTPase Signaling
Cited by 1,321
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TGF-β and the TGF-β family: context-dependent roles in cell and tissue physiology
Morikawa, M., Derynck, R., & Miyazono, K. (2016) · Cold Spring Harbor Perspectives in Biology
TGF-β signaling in diseasesLiver physiology and pathology
Cited by 1,321
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Quantitative real-time RT-PCR – a perspective
Bustin, S. A., Benes, V, Nolan, T., & Pfaffl, M. W. (2005) · Journal of Molecular Endocrinology
Molecular Biology Techniques and ApplicationsRNA Research and Splicing
Cited by 1,321
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Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1
Bohmann, D., Bos, T. J., Admon, A., Nishimura, T., Vogt, P. K., & Tjian, R. (1987) · Science
Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling
Cited by 1,321
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Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
Thaker, P. H., Han, L. Y., Kamat, A. A., Arevalo, J. M., Takahashi, R., Lu, C., Jennings, N. B., Armaiz-Pena, G., Bankson, J. A., Ravoori, M., et al. (2006) · Nature Medicine
Cancer, Stress, Anesthesia, and Immune ResponseAngiogenesis and VEGF in Cancer
Cited by 1,320
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Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine
Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Pich, E. M., Fuxe, K., & Changeux, J.-P. (1998) · Nature
Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation
Cited by 1,320
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The microbiology of butyrate formation in the human colon
Pryde, S. E., Duncan, S. H., Hold, G. L., Stewart, C. S., & Flint, H. J. (2002) · FEMS Microbiology Letters
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 1,320
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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25
Sanchez, Y., Wong, C., Thoma, R. S., Richman, R., Wu, Z., Piwnica-Worms, H., & Elledge, S. J. (1997) · Science
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,320
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Extracellular vesicles for drug delivery.
Vader, P., Mol, E. A., Pasterkamp, G., & Schiffelers, R. M. (2016) · Advanced Drug Delivery Reviews
Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery
Cited by 1,319
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Telomere dysfunction induces metabolic and mitochondrial compromise
Sahin, E., Colla, S., Liesa, M., Moslehi, J., Müller, F. L., Guo, M., Cooper, M., Kotton, D., Fabian, A. J., Walkey, C., et al. (2011) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,319
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PIWI-interacting small RNAs: the vanguard of genome defence
Siomi, M. C., Sato, K., Pezic, D., & Aravin, A. A. (2011) · Nature Reviews Molecular Cell Biology
Chromosomal and Genetic VariationsRNA Interference and Gene Delivery
Cited by 1,319
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Diseases of the mitochondrial DNA
Wallace, D. C. (1992) · Annual Review of Biochemistry
Mitochondrial Function and PathologyMetabolism and Genetic Disorders
Cited by 1,319
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A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
Deeb, S. S., Fajas, L., Nemoto, M., Pihlajamäki, J., Mykkänen, L., Kuusisto, J., Laakso, M., Fujimoto, W., & Auwerx, J. (1998) · Nature Genetics
Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases
Cited by 1,319
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Data quality control in genetic case-control association studies
Anderson, C. A., Pettersson, F. H., Clarke, G. M., Cardon, L. R., Morris, A. P., & Zondervan, K. T. (2010) · Nature Protocols
Genetic Associations and EpidemiologyGenetic diversity and population structure
Cited by 1,318
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