Most cited biochemistry, genetics and molecular biology papers
- Verified
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
Kondo, K., Klco, J., Nakamura, E., Lechpammer, M., & Kaelin, W. G. (2002) · Cancer Cell
Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment
Cited by 761
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Engineering adeno-associated viruses for clinical gene therapy
Kotterman, M. A., & Schaffer, D. V. (2014) · Nature Reviews Genetics
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 761
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Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells
Stauffer, T. P., Ahn, S., & Meyer, T. (1998) · Current Biology
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 761
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Genetic studies in intellectual disability and related disorders
Vissers, L. E. L. M., Gilissen, C., & Veltman, J. A. (2016) · Nature Reviews Genetics
Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases
Cited by 761
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Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
Ferrari, F. K., Samulski, T., Shenk, T., & Samulski, R. J. (1996) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 761
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Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
Takahashi, A., Okada, R., Nagao, K., Kawamata, Y., Hanyu, A., Yoshimoto, S., Takasugi, M., Watanabe, S., Kanemaki, M. T., Obuse, C., et al. (2017) · Nature Communications
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 761
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Oxidative Stress Resistance in Deinococcus radiodurans
Slade, D., & Radman, M. (2011) · Microbiology and Molecular Biology Reviews
Redox biology and oxidative stressEffects of Radiation Exposure
Cited by 761
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The actin cytoskeleton and actin-based motility
Svitkina, T. (2018) · Cold Spring Harbor Perspectives in Biology
Cellular Mechanics and InteractionsMicrotubule and mitosis dynamics
Cited by 761
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Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response
Vaupel, P., & Harrison, L. (2004) · The Oncologist
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 761
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Inflammasomes in neuroinflammatory and neurodegenerative diseases
Voet, S., Srinivasan, S., Lamkanfi, M., & van Loo, G. (2019) · EMBO Molecular Medicine
Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms
Cited by 761
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NAADP mobilizes calcium from acidic organelles through two-pore channels
Calcraft, P. J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K.-T., et al. (2009) · Nature
Calcium signaling and nucleotide metabolismIon Channels and Receptors
Cited by 760
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Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour
Desbonnet, L., Clarke, G., Traplin, A., O’Sullivan, O., Crispie, F., Moloney, R. D., Cotter, P. D., Dinan, T. G., & Cryan, J. F. (2015) · Brain Behavior and Immunity
Gut microbiota and healthTryptophan and brain disorders
Cited by 760
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Hot spots—A review of the protein–protein interface determinant amino‐acid residues
Moreira, I. S., Fernandes, P. A., & Ramos, M. J. (2007) · Proteins: Structure, Function, and Bioinformatics
Protein Structure and DynamicsProtein Interaction Studies and Fluorescence Analysis
Cited by 760
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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
Nuñez, J. K., Chen, J., Pommier, G. C., Cogan, J. Z., Replogle, J. M., Adriaens, C., Ramadoss, G. N., Shi, Q., Hung, K. L., Samelson, A. J., et al. (2021) · Cell
CRISPR and Genetic EngineeringEpigenetics and DNA Methylation
Cited by 760
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Small Molecule Modulators of Keap1‐ Nrf2‐ ARE Pathway as Potential Preventive and Therapeutic Agents
Magesh, S., Chen, Y., & Hu, L. (2012) · Medicinal Research Reviews
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 760
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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
Lagger, G., O'Carroll, D., Rembold, M., Khier, H., Tischler, J., Weitzer, G., Schuettengruber, B., Hauser, C., Brunmeir, R., Jenuwein, T., et al. (2002) · The EMBO Journal
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 760
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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A Phase 2 Trial of Intracoronary Gene Therapy of Sarcoplasmic Reticulum Ca 2+ -ATPase in Patients With Advanced Heart Failure
Jessup, M., Greenberg, B., Mancini, D., Cappola, T., Pauly, D. F., Jaski, B., Yaroshinsky, A., Zsebo, K. M., Dittrich, H., & Hajjar, R. J. (2011) · Circulation
Virus-based gene therapy researchHeart Failure Treatment and Management
Cited by 760
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Expression of Nrf2 in Neurodegenerative Diseases
Ramsey, C. P., Glass, C. A., Montgomery, M. B., Lindl, K. A., Ritson, G. P., Chia, L. A., Hamilton, R. L., Chu, C. T., & Jordan-Sciutto, K. L. (2007) · Journal of Neuropathology and Experimental Neurology
Genomics, phytochemicals, and oxidative stressAlzheimer's disease research and treatments
Cited by 760
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In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract
Arnaoutova, I., & Kleinman, H. K. (2010) · Nature Protocols
Angiogenesis and VEGF in CancerCell Adhesion Molecules Research
Cited by 760
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Identification of a candidate therapeutic autophagy-inducing peptide
Shoji-Kawata, S., Sumpter, R., Leveno, M., Campbell, G. R., Zou, Z., Kinch, L., Wilkins, A. D., Sun, Q., Pallauf, K., MacDuff, D., et al. (2013) · Nature
Autophagy in Disease and TherapyRNA Interference and Gene Delivery
Cited by 760
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Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity
Ioannou, M. S., Jackson, J., Sheu, S.-H., Chang, C.-L., Weigel, A. V., Liu, H., Pasolli, H. A., Xu, C. S., Pang, S., Matthies, D., et al. (2019) · Cell
Lipid metabolism and biosynthesisNeuroscience and Neuropharmacology Research
Cited by 760
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Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
Mashimo, T., Pichumani, K., Vemireddy, V., Hatanpaa, K. J., Singh, D. K., Sirasanagandla, S., Nannepaga, S., Piccirillo, S. G., Kovacs, Z., Foong, C., et al. (2014) · Cell
Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism
Cited by 760
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A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility
Cusanovich, D. A., Hill, A. J., Aghamirzaie, D., Daza, R. M., Pliner, H. A., Berletch, J. B., Filippova, G. N., Huang, X., Christiansen, L., DeWitt, W. S., et al. (2018) · Cell
Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics
Cited by 759
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SCF/β-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner
Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D., & Cuadrado, A. (2011) · Molecular and Cellular Biology
Genomics, phytochemicals, and oxidative stressUbiquitin and proteasome pathways
Cited by 759
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