Most cited biochemistry, genetics and molecular biology papers
- Verified
Probabilistic harmonization and annotation of single‐cell transcriptomics data with deep generative models
Xu, C., Lopez, R., Mehlman, E., Regier, J., Jordan, M. I., & Yosef, N. (2021) · Molecular Systems Biology
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 691
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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism
Lito, P., Solomon, M., Li, L.-S., Hansen, R., & Rosen, N. (2016) · Science
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 691
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Postnatal neurodevelopmental disorders: meeting at the synapse?
Zoghbi, H. Y. (2003) · Science
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 691
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Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice
Lin, Z., Tian, H., Lam, K. S. L., Lin, S., Hoo, R. C. L., Konishi, M., Itoh, N., Wang, Y., Bornstein, S. R., Xu, A., et al. (2013) · Cell Metabolism
Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases
Cited by 691
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Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product
Anderson, K. V., Jürgens, G., & Nüsslein-Volhard, C. (1985) · Cell
Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics
Cited by 691
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Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health
Chambers, E. S., Preston, T., Frost, G., & Morrison, D. J. (2018) · Current Nutrition Reports
Gut microbiota and healthMicrobial Metabolites in Food Biotechnology
Cited by 691
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The contribution of the large intestine to energy supplies in man
N I, M. (1984) · The American Journal of Clinical Nutrition
Gut microbiota and healthRuminant Nutrition and Digestive Physiology
Cited by 691
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The metabolic roots of senescence: mechanisms and opportunities for intervention
Wiley, C. D., & Campisi, J. (2021) · Nature Metabolism
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 691
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TSH Is a Negative Regulator of Skeletal Remodeling
Abe, E., Marians, R. C., Yu, W., Wu, X.-B., Ando, T., Li, Y., Iqbal, J., Eldeiry, L., Rajendren, G., Blair, H. C., et al. (2003) · Cell
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 691
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Bone morphogenetic proteins: a critical review
Bragdon, B., Moseychuk, O., Saldanha, S., King, D., Julian, J., & Nohe, A. (2011) · Cellular Signalling
TGF-β signaling in diseasesDevelopmental Biology and Gene Regulation
Cited by 691
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Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits
Merrifield, C. J., Feldman, M. E., Wan, L., & Almers, W. (2002) · Nature Cell Biology
Cellular transport and secretionCaveolin-1 and cellular processes
Cited by 691
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Ras Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen Species
Lee, A. C., Fenster, B. E., Ito, H., Takeda, K., Bae, N. S., Hirai, T., Yu, Z.-X., Ferrans, V. J., Howard, B. H., & Finkel, T. (1999) · Journal of Biological Chemistry
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 691
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Missing Data, Incomplete Taxa, and Phylogenetic Accuracy
Wiens, J. J. (2003) · Systematic Biology
Genomics and Phylogenetic StudiesEvolution and Paleontology Studies
Cited by 691
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Eukaryotic DNA Polymerases
Hübscher, U., Maga, G., & Spadari, S. (2002) · Annual Review of Biochemistry
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 691
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Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
Iyer, S. S., Pulskens, W. P., Sadler, J. J., Butter, L. M., Teske, G. J., Ulland, T. K., Eisenbarth, S. C., Florquin, S., Flavell, R. A., Leemans, J. C., et al. (2009) · Proceedings of the National Academy of Sciences
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 691
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Human body epigenome maps reveal noncanonical DNA methylation variation
Schultz, M. D., He, Y., Whitaker, J. W., Hariharan, M., Mukamel, E. A., Leung, D., Rajagopal, N., Nery, J. R., Urich, M. A., Chen, H., et al. (2015) · Nature
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 690
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Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways
Benson, D. W., Silberbach, G. M., Kavanaugh-McHugh, A., Cottrill, C., Zhang, Y., Riggs, S., Smalls, O., Johnson, M. C., Watson, M. S., Seidman, J. G., et al. (1999) · Journal of Clinical Investigation
Congenital heart defects researchCardiac electrophysiology and arrhythmias
Cited by 690
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Epigenetics and aging: the targets and the marks
Fraga, M. F., & Esteller, M. (2007) · Trends in Genetics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 690
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Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids
Zheng, C. J., Yoo, J.-S., Lee, T.-G., Cho, H.-Y., Kim, Y.-H., & Kim, W.-G. (2005) · FEBS Letters
Lipid metabolism and biosynthesisCancer, Lipids, and Metabolism
Cited by 690
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The Genesis of Neural Crest and Epidermal Placodes: A Reinterpretation of Vertebrate Origins
Northcutt, R. G., & Gans, C. (1983) · The Quarterly Review of Biology
Developmental Biology and Gene RegulationPaleontology and Evolutionary Biology
Cited by 690
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Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
Um, S. H., D'Alessio, D., & Thomas, G. (2006) · Cell Metabolism
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 690
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Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
Rayner, K. J., Sheedy, F. J., Esau, C. C., Hussain, F. N., Temel, R. E., Parathath, S., van Gils, J. M., Rayner, A. J., Chang, A. N., Suarez, Y., et al. (2011) · Journal of Clinical Investigation
Cholesterol and Lipid MetabolismMicroRNA in disease regulation
Cited by 690
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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
Carvajal-Vergara, X., Sevilla, A., D’Souza, S. L., Ang, Y.-S., Schaniel, C., Lee, D.-F., Yang, L., Kaplan, A. D., Adler, E. D., Rozov, R., et al. (2010) · Nature
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 690
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Functional Redundancy-Induced Stability of Gut Microbiota Subjected to Disturbance
Moya, A., & Ferrer, M. (2016) · Trends in Microbiology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 690
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