Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Quantification of mRNA using real-time RT-PCR

Nolan, T., Hands, R. E., & Bustin, S. A. (2006) · Nature Protocols

Molecular Biology Techniques and ApplicationsRNA Research and Splicing

Cited by 2,247

Histone methylation: a dynamic mark in health, disease and inheritance

Greer, E. L., & Shi, Y. (2012) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,241

Hypoxia in cancer: significance and impact on clinical outcome

Vaupel, P., & Mayer, A. (2007) · Cancer and Metastasis Reviews

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 2,240

DNA damage, aging, and Cancer

Hoeijmakers, J. H. J. (2009) · New England Journal of Medicine

DNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 2,239

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

Zhang, S. H., Reddick, R. L., Piedrahita, J. A., & Maeda, N. (1992) · Science

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 2,237

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Anzalone, A. V., Koblan, L. W., & Liu, D. R. (2020) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,237

Microbial tryptophan catabolites in health and disease

Roager, H. M., & Licht, T. R. (2018) · Nature Communications

Gut microbiota and healthTryptophan and brain disorders

Cited by 2,236

22q11.2 deletion syndrome

McDonald-McGinn, D. M., Sullivan, K. E., Marino, B., Philip, N., Swillen, A., Vorstman, J. A. S., Zackai, E. H., Emanuel, B. S., Vermeesch, J. R., Morrow, B. E., et al. (2015) · Nature Reviews Disease Primers

Genomic variations and chromosomal abnormalitiesImmunodeficiency and Autoimmune Disorders

Cited by 2,236

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

Merico, D., Isserlin, R., Stueker, O., Emili, A., & Bader, G. D. (2010) · PLoS ONE

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 2,235

Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jäger, S., Handschin, C., Zheng, K., Lin, J., Yang, W., et al. (2006) · Cell

Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments

Cited by 2,233

A unique chromatin signature uncovers early developmental enhancers in humans

Rada-Iglesias, A., Bajpai, R., Swigut, T., Brugmann, S. A., Flynn, R. A., & Wysocka, J. (2011) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,233

The human cell atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P., Carninci, P., Clatworthy, M., et al. (2017) · eLife

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 2,232

Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

Evans, J. L., Goldfine, I. D., Maddux, B. A., & Grodsky, G. M. (2002) · Endocrine Reviews

Advanced Glycation End Products researchNitric Oxide and Endothelin Effects

Cited by 2,232

Factors influencing the composition of the intestinal microbiota in early infancy

Penders, J., Thijs, C., Vink, C., Stelma, F. F., Snijders, B., Kummeling, I., van den Brandt, P. A., & Stobberingh, E. E. (2006) · PEDIATRICS

Gut microbiota and healthInfant Nutrition and Health

Cited by 2,232

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

Rodier, F., Coppé, J.-P., Patil, C. K., Hoeijmakers, W. A. M., Muñoz, D. P., Raza, S. R., Freund, A., Campeau, E., Davalos, A. R., & Campisi, J. (2009) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 2,232

The InterPro protein families and domains database: 20 years on

Blum, M., Chang, H.-Y., Chuguransky, S., Grego, T., Kandasaamy, S., Mitchell, A., Nuka, G., Paysan-Lafosse, T., Qureshi, M., Raj, S., et al. (2021) · Nucleic Acids Research

Genomics and Phylogenetic StudiesMachine Learning in Bioinformatics

Cited by 2,231

Current best practices in single-cell RNA-seq analysis: a tutorial

Luecken, M. D., & Theis, F. J. (2019) · Molecular Systems Biology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 2,231

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Inflammasomes in health and disease

Strowig, T., Henao-Mejia, J., Elinav, E., & Flavell, R. (2012) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,230

The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

Shtutman, M., Zhurinsky, J., Simcha, I., Albanese, C., D’Amico, M., Pestell, R., & Ben-Ze’ev, A. (1999) · Proceedings of the National Academy of Sciences

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 2,230

Mendelian randomization

Sanderson, E., Glymour, M. M., Holmes, M. V., Kang, H., Morrison, J., Munafò, M. R., Palmer, T., Schooling, C. M., Wallace, C., Zhao, Q., et al. (2022) · Nature Reviews Methods Primers

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 2,229

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

Ward, L. D., & Kellis, M. (2012) · Nucleic Acids Research

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 2,229

Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2

King, M.-C., Marks, J. H., & Mandell, J. B. (2003) · Science

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 2,229

The RNA Component of Human Telomerase

Feng, J., Funk, W. D., Wang, S.-S., Weinrich, S. L., Avilion, A. A., Chiu, C.-P., Adams, R. R., Chang, E., Allsopp, R. C., Yu, J., et al. (1995) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,227