Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Creation of human tumour cells with defined genetic elements

Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W., & Weinberg, R. A. (1999) · Nature

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 2,345

Mediators of endoplasmic reticulum stress-induced apoptosis

Szegezdi, E., Logue, S. E., Gorman, A. M., & Samali, A. (2006) · The EMBO Reports

Endoplasmic Reticulum Stress and DiseaseCell death mechanisms and regulation

Cited by 2,345

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

WISEMAN, H., & HALLIWELL, B. (1996) · Biochemical Journal

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,345

Structure and Regulation of Voltage-Gated Ca 2+ Channels

Catterall, W. A. (2000) · Annual Review of Cell and Developmental Biology

Ion channel regulation and functionCardiac electrophysiology and arrhythmias

Cited by 2,344

A microbial symbiosis factor prevents intestinal inflammatory disease

Mazmanian, S. K., Round, J. L., & Kasper, D. L. (2008) · Nature

Gut microbiota and healthInflammatory Bowel Disease

Cited by 2,340

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

Huntzinger, E., & Izaurralde, E. (2011) · Nature Reviews Genetics

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 2,339

Cas-OFFinder: A fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Bae, S., Park, J., & Kim, J.-S. (2014) · Bioinformatics

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,339

Predicting effects of noncoding variants with deep learning–based sequence model

Zhou, J., & Troyanskaya, O. G. (2015) · Nature Methods

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 2,338

Tumor cell metabolism: cancer's Achilles' heel

Kroemer, G., & Pouyssegur, J. (2008) · Cancer Cell

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 2,337

Scaffolding pre-assembled contigs using SSPACE.

Boetzer, M., Henkel, C. V., Jansen, H. J., Butler, D., & Pirovano, W. (2011) · Bioinformatics

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 2,337

The role of m6A modification in the biological functions and diseases

Jiang, X., Liu, B., Nie, Z., Duan, L., Xiong, Q., Jin, Z., Yang, C., & Chen, Y. (2021) · Signal Transduction and Targeted Therapy

RNA modifications and cancerRNA regulation and disease

Cited by 2,335

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

Magne, F., Gotteland, M., Gauthier, L., Zazueta, A., Pesoa, S., Navarrete, P., & Balamurugan, R. (2020) · Nutrients

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,335

Autophagy promotes ferroptosis by degradation of ferritin

Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., Kang, R., & Tang, D. (2016) · Autophagy

Ferroptosis and cancer prognosisAutophagy in Disease and Therapy

Cited by 2,332

Adipose-derived stem cells for regenerative medicine

Gimble, J. M., Katz, A. J., & Bunnell, B. A. (2007) · Circulation Research

Mesenchymal stem cell researchTissue Engineering and Regenerative Medicine

Cited by 2,332

Combinatorial patterns of histone acetylations and methylations in the human genome

Wang, Z., Zang, C., Rosenfeld, J. A., Schones, D. E., Barski, A., Cuddapah, S., Cui, K., Roh, T.-Y., Peng, W., Zhang, M. Q., et al. (2008) · Nature Genetics

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,331

Microbial degradation of complex carbohydrates in the gut

Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P., & Forano, E. (2012) · Gut Microbes

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 2,331

Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice

Komatsu, M., Waguri, S., Ueno, T., Iwata, J., Murata, S., Tanida, I., Ezaki, J., Mizushima, N., Ohsumi, Y., Uchiyama, Y., et al. (2005) · The Journal of Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,331

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena

Kruger, K., Grabowski, P. J., Zaug, A. J., Sands, J., Gottschling, D. E., & Cech, T. R. (1982) · Cell

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 2,331

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

Sayin, S. I., Wahlström, A., Felin, J., Jäntti, S., Marschall, H.-U., Bamberg, K., Angelin, B., Hyötyläinen, T., Orešič, M., & Bäckhed, F. (2013) · Cell Metabolism

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 2,331

ProtTrans: Toward Understanding the Language of Life Through Self-Supervised Learning

Elnaggar, A., Heinzinger, M., Dallago, C., Rehawi, G., Wang, Y., Jones, L., Gibbs, T., Feher, T., Angerer, C., Steinegger, M., et al. (2022) · IEEE Transactions on Pattern Analysis and Machine Intelligence

Machine Learning in BioinformaticsProtein Structure and Dynamics

Cited by 2,329

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Yang, W. S., Kim, K. J., Gaschler, M. M., Patel, M., Shchepinov, M. S., & Stockwell, B. R. (2016) · Proceedings of the National Academy of Sciences

Ferroptosis and cancer prognosisAntioxidant Activity and Oxidative Stress

Cited by 2,329

Local force and geometry sensing regulate cell functions

Vogel, V., & Sheetz, M. (2006) · Nature Reviews Molecular Cell Biology

Cellular Mechanics and InteractionsForce Microscopy Techniques and Applications

Cited by 2,328

The development of androgen-independent prostate cancer.

Feldman, B. J., & Feldman, D. (2001) · Nature reviews. Cancer

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 2,326

De novo design of protein structure and function with RFdiffusion

Watson, J. L., Juergens, D., Bennett, N. R., Trippe, B. L., Yim, J., Eisenach, H. E., Ahern, W., Borst, A. J., Ragotte, R. J., Milles, L. F., et al. (2023) · Nature

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 2,325