Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,166

Ultrafast one‐pass FASTQ data preprocessing, quality control, and deduplication using fastp

Chen, S. (2023) · iMeta

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 2,166

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

Kujoth, G. C., Hiona, A., Pugh, T. D., Someya, S., Panzer, K., Wohlgemuth, S. E., Hofer, T., Seo, A. Y., Sullivan, R., Jobling, W. A., et al. (2005) · Science

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 2,165

Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

Koren, O., Goodrich, J. K., Cullender, T. C., Spor, A., Laitinen, K., Kling Bäckhed, H., Gonzalez, A., Werner, J. J., Angenent, L. T., Knight, R., et al. (2012) · Cell

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,165

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., et al. (1997) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health

Cited by 2,164

An integrated catalog of reference genes in the human gut microbiome

MetaHIT Consortium, Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., et al. (2014) · Nature Biotechnology

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 2,164

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Manno, C. S., Pierce, G. F., Arruda, V. R., Glader, B., Ragni, M., Rasko, J. J. E., Ozelo, M. C., Hoots, K., Blatt, P., Konkle, B., et al. (2006) · Nature Medicine

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 2,163

Accurate proteome-wide missense variant effect prediction with AlphaMissense

Cheng, J., Novati, G., Pan, J., Bycroft, C., Žemgulytė, A., Applebaum, T., Pritzel, A., Wong, L. H., Zielinski, M., Sargeant, T., et al. (2023) · Science

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 2,163

The Genetic Landscape of a Cell

Costanzo, M., Baryshnikova, A., Bellay, J., Kim, Y., Spear, E. D., Sevier, C. S., Ding, H., Koh, J. L. Y., Toufighi, K., Mostafavi, S., et al. (2010) · Science

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 2,162

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

MacArthur, J., Bowler, E., Cerezo, M., Gil, L., Hall, P., Hastings, E., Junkins, H., McMahon, A., Milano, A., Morales, J., et al. (2017) · Nucleic Acids Research

Genetic Associations and EpidemiologyResearch Data Management Practices

Cited by 2,161

H 2 O 2 , a Necessary Evil for Cell Signaling

Rhee, S. G. (2006) · Science

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 2,160

BRAFE600-associated senescence-like cell cycle arrest of human naevi

Michaloglou, C., Vredeveld, L. C. W., Soengas, M. S., Denoyelle, C., Kuilman, T., van der Horst, C. M. A. M., Majoor, D. M., Shay, J. W., Mooi, W. J., & Peeper, D. S. (2005) · Nature

Telomeres, Telomerase, and SenescenceMelanoma and MAPK Pathways

Cited by 2,160

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Frampton, G. M., Fichtenholtz, A., Otto, G. A., Wang, K., Downing, S. R., He, J., Schnall-Levin, M., White, J., Sanford, E. M., An, P., et al. (2013) · Nature Biotechnology

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 2,157

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

OWEN, M. R., DORAN, E., & HALESTRAP, A. P. (2000) · Biochemical Journal

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 2,157

Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy

Denkert, C., von Minckwitz, G., Darb-Esfahani, S., Lederer, B., Heppner, B. I., Weber, K. E., Budczies, J., Huober, J., Klauschen, F., Furlanetto, J., et al. (2018) · The Lancet Oncology

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 2,157

Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

Sosman, J. A., Kim, K. B., Schuchter, L., Gonzalez, R., Pavlick, A. C., Weber, J. S., McArthur, G. A., Hutson, T. E., Moschos, S. J., Flaherty, K. T., et al. (2012) · New England Journal of Medicine

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 2,156

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

Kusumbe, A. P., Ramasamy, S. K., & Adams, R. H. (2014) · Nature

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 2,155

The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms

Ceri, H., Olson, M. E., Stremick, C., Read, R. R., Morck, D., & Buret, A. (1999) · Journal of Clinical Microbiology

Bacterial biofilms and quorum sensingAntifungal resistance and susceptibility

Cited by 2,155

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A., & McMahon, A. P. (1993) · Cell

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene Regulation

Cited by 2,154

Protein S-nitrosylation: Purview and parameters

Hess, D. T., Matsumoto, A., Kim, S.-O., Marshall, H. E., & Stamler, J. S. (2005) · Nature Reviews Molecular Cell Biology

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 2,153

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

Otterbein, L. E., Bach, F. H., Alam, J., Soares, M., Tao Lu, H., Wysk, M., Davis, R. J., Flavell, R. A., & Choi, A. M. K. (2000) · Nature Medicine

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 2,153

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

Kamei, Y., Xu, L., Heinzel, T., Torchia, J., Kurokawa, R., Gloss, B., Lin, S.-C., Heyman, R. A., Rose, D. W., Glass, C. K., et al. (1996) · Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 2,150

The gut microbiota–brain axis in behaviour and brain disorders

Morais, L. H., Schreiber, H. L., & Mazmanian, S. K. (2021) · Nature Reviews Microbiology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 2,149

Aggresomes: A Cellular Response to Misfolded Proteins

Johnston, J. A., Ward, C. L., & Kopito, R. R. (1998) · The Journal of Cell Biology

Ubiquitin and proteasome pathwaysHeat shock proteins research

Cited by 2,148