Most cited biochemistry, genetics and molecular biology papers
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The spindle-assembly checkpoint in space and time
Musacchio, A., & Salmon, E. D. (2007) · Nature Reviews Molecular Cell Biology
Microtubule and mitosis dynamicsDNA Repair Mechanisms
Cited by 2,227
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Transcription factors: from enhancer binding to developmental control
Spitz, F., & Furlong, E. E. M. (2012) · Nature Reviews Genetics
Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation
Cited by 2,227
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METLIN—a metabolite mass spectral database
Smith, C. A., Maille, G. O., Want, E. J., Qin, C., Trauger, S. A., Brandon, T. R., Custodio, D. E., Abagyan, R., & Siuzdak, G. (2005) · Therapeutic Drug Monitoring
Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications
Cited by 2,226
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Effects of extracellular matrix viscoelasticity on cellular behaviour
Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature
Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications
Cited by 2,224
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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
Shibutani, S., Takeshita, M., & Grollman, A. P. (1991) · Nature
DNA Repair MechanismsDNA and Nucleic Acid Chemistry
Cited by 2,224
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Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
Kobayashi, A., Kang, M.-I., Okawa, H., Ohtsuji, M., Zenke, Y., Chiba, T., Igarashi, K., & Yamamoto, M. (2004) · Molecular and Cellular Biology
Genomics, phytochemicals, and oxidative stressUbiquitin and proteasome pathways
Cited by 2,224
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Molecular mechanism and physiological functions of clathrin-mediated endocytosis
McMahon, H. T., & Boucrot, E. (2011) · Nature Reviews Molecular Cell Biology
Cellular transport and secretionCaveolin-1 and cellular processes
Cited by 2,223
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Circular intronic long noncoding RNAs
Zhang, Y., Zhang, X.-O., Chen, T., Xiang, J.-F., Yin, Q.-F., Xing, Y.-H., Zhu, S., Yang, L., & Chen, L.-L. (2013) · Molecular Cell
RNA Research and SplicingCircular RNAs in diseases
Cited by 2,221
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An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Newman, A. M., Bratman, S. V., To, J., Wynne, J. F., Eclov, N. C. W., Modlin, L. A., Liu, C. L., Neal, J. W., Wakelee, H. A., Merritt, R. E., et al. (2014) · Nature Medicine
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 2,220
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Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., et al. (2013) · Nature
Gut microbiota and healthTelomeres, Telomerase, and Senescence
Cited by 2,219
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Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., et al. (2016) · Nature
Cancer Genomics and DiagnosticsBRCA gene mutations in cancer
Cited by 2,218
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Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
Braissant, O., Foufelle, F., Scotto, C., Dauça, M., & Wahli, W. (1996) · Endocrinology
Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism
Cited by 2,217
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ChIP–seq: advantages and challenges of a maturing technology
Park, P. J. (2009) · Nature Reviews Genetics
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 2,217
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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
Lai, R. C., Arslan, F., Lee, M. M., Sze, N. S. K., Choo, A., Chen, T. S., Salto-Tellez, M., Timmers, L., Lee, C. N., El Oakley, R. M., et al. (2010) · Stem Cell Research
Extracellular vesicles in diseaseMesenchymal stem cell research
Cited by 2,215
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A human retinoic acid receptor which belongs to the family of nuclear receptors
Petkovich, M., Brand, N. J., Krust, A., & Chambon, P. (1987) · Nature
Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors
Cited by 2,214
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Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
He, S., Wang, L., Miao, L., Wang, T., Du, F., Zhao, L., & Wang, X. (2009) · Cell
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 2,214
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BUSCO applications from quality assessments to gene prediction and phylogenomics
Waterhouse, R. M., Seppey, M., Simão, F. A., Manni, M., Ioannidis, P., Klioutchnikov, G., Kriventseva, E. V., & Zdobnov, E. M. (2018) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 2,214
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Electrochemical DNA sensors
Drummond, T. G., Hill, M. G., & Barton, J. K. (2003) · Nature Biotechnology
Advanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensors
Cited by 2,214
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
Taliun, D., Harris, D. N., Kessler, M. D., Carlson, J., Szpiech, Z. A., Torres, R., Taliun, S. A. G., Corvelo, A., Gogarten, S. M., Kang, H. M., et al. (2021) · Nature
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 2,213
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Safety and antitumor activity of recombinant soluble Apo2 ligand
Ashkenazi, A., Pai, R. C., Fong, S., Leung, S., Lawrence, D. A., Marsters, S. A., Blackie, C., Chang, L., McMurtrey, A. E., Hebert, A., et al. (1999) · Journal of Clinical Investigation
Cell death mechanisms and regulationToxin Mechanisms and Immunotoxins
Cited by 2,213
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Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
Zelko, I. N., Mariani, T. J., & Folz, R. J. (2002) · Free Radical Biology and Medicine
Glutathione Transferases and PolymorphismsRedox biology and oxidative stress
Cited by 2,212
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Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
Xie, Q. W., Kashiwabara, Y., & Nathan, C. (1994) · Journal of Biological Chemistry
NF-κB Signaling PathwaysImmune Response and Inflammation
Cited by 2,212
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THEORY OF PROTEIN FOLDING: The Energy Landscape Perspective
Onuchic, J. N., Luthey-Schulten, Z., & Wolynes, P. G. (1997) · Annual Review of Physical Chemistry
Protein Structure and DynamicsRNA and protein synthesis mechanisms
Cited by 2,210
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Liquid Biopsies: Genotyping Circulating Tumor DNA
Diaz, L. A., & Bardelli, A. (2014) · Journal of Clinical Oncology
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 2,210
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